Clinical trials: Dysphoric Mood
Gender Dysphoria
Gender Dysphoria and Transition
Persons with gender dysphoria present the difficulties of access to health care. Little time is devoted to education of health professionals about the care of transgender persons.
- Trial name
- DyGePeT (NCT04265885)
- Testing
- collection of testimonies from transgender people
- Volunteers
- 10 people
- Sponsor
- Central Hospital, Nancy, France
Contraception, Premenstrual Syndrome
Regulatory Post Marketing Surveillance Study on YAZ
The objective of this Post Marketing Surveillance (PMS) is to gain information about safety and efficacy in real practice.
- Conditions
- Contraception, Premenstrual Syndrome, Acne
- Trial name
- NCT00998257
- Testing
- EE20/DRSP (YAZ, BAY86-5300)
- Where
- South Korea
- Volunteers
- 770 people
- Sponsor
- Bayer
Stigma, Social, Gays
An LGBT-Competency Program for Mental Health Professionals in Romania
Lesbian, gay, bisexual and transgender individuals (LGBTI) present increased morbidity compared to the general population, which is attributed to healthcare discrimination and lack of LGBT-specific expertise, especially in…
- Conditions
- Stigma, Social, Gays, Lesbians, Bisexuals
- Trial name
- NCT03602222
- Testing
- Mobile web training LGBT mental health, In-person training LGBT mental health
- Where
- Romania
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Premenstrual Dysphoric Disorder (PMDD)
Occupational Physicians Facing Premenstrual Dysphoric Disorder: Knowledge, Perceptions and Practices in Occupational Health
This study aims to assess the knowledge, perceptions and practices of occupational physicians regarding premenstrual dysphoric disorder (PMDD), a condition with significant occupational impact that remains insufficiently explored…
- Trial name
- TDPM (NCT07864285)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Strasbourg, France
Dysphoric Mood
Components of Placebo Effects in Sadness
Research has shown that placebo effects contribute substantially to clinical outcomes. Recent evidence suggests that placebos remain effective even if they are openly described as placebos (so-called Open-Label Placebos).
- Trial name
- COPES (NCT03507959)
- Testing
- OLP scientifically-objective, OLP personally-affective, DP scientifically-objective
- Where
- Germany
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Premenstrual Dysphoric Disorder ( PMDD), PMDD
MLS101 Study in PMDD
The goal of this clinical trial is to learn if MLS101 (psilocybin) is a possible treatment for women with Premenstrual Dysphoric Disorder (PMDD).
- Trial name
- NCT07818720
- Testing
- MLS101 psilocybin
- Volunteers
- 32 people
- Sponsor
- MycoMedica Life Sciences PBC
Gender Dysphoria, Gender Identity Disorder
i2TransHealth: Interdisciplinary, Internet-based Trans Health Care
i2TransHealth is a randomized controlled trial that investigates the outcomes of an internet-based health care approach for transgender and gender diverse (TGD) people.
- Conditions
- Gender Dysphoria, Gender Identity Disorder, Transsexualism, Gender Identity
- Trial name
- NCT04290286
- Testing
- i2TransHealth
- Where
- Germany
- Volunteers
- 186 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Premenstrual Dysphoric Disorder
Alternative Treatments for Premenstrual Dysphoric Disorder
The primary aim of this study is to examine the effects of co-administered wake therapy followed by light treatment on mood, and secondarily on circadian rhythms, to test the hypothesis that critically-timed chronotherapy…
- Trial name
- NCT01799733
- Testing
- LWT+AM BWL, EWT+PM BWL
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of California, San Diego
Gender Dysphoria
Acoustic and Perceptual Effects of Intonation Training in Gender Diverse People
The aim of this project is to investigate the short- and the longer-term effect of intonation training on vocal characteristics, listener perceptions and patient related outcome measures (PROMS) in gender diverse people using a…
- Trial name
- B6702021001262 (NCT05204732)
- Testing
- Intonation training
- Where
- Belgium
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University Ghent
Gender Dysphoria
Development of Effective, Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients Undergoing Gender Affirming Surgeries
This study will compare the current standard-of-care pain treatment regimen options that are available to patients who undergo gender-affirming surgery.
- Trial name
- NCT04979338
- Testing
- Ultrasound guided Continuous Infraclavicular Brachial Plexus Block, Ultrasound guided Continuous Femoral Nerve Block, Ultrasound guided Pudendal Nerve Block
- Where
- United States
- Volunteers
- 640 people
- Sponsor
- Cedars-Sinai Medical Center
Premenstrual Syndrome, PMS
Treatment of Menstrually Related Disorders With Continuous v. Interrupted Oral Contraceptives
This study will determine whether uninterrupted treatment with birth control pills over several menstrual cycles prevents severe premenstrual syndrome (PMDD).
- Conditions
- Premenstrual Syndrome, PMS, Premenstrual Dysphoric Disorder, PMDD
- Trial name
- NCT00089414
- Testing
- Ethinyl Estradiol/Drospirenone, CDB 2914
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Mental Health (NIMH)
Gender Dysphoria
Demographic Characteristics and Psychosocial Health of Transgender People
To study demographic characteristics of subjects referred to endocrine care for gender dysphoria and their psychosocial health
- Trial name
- DyGeDem (NCT04554849)
- Testing
- Gender dysphoria psychosocial health
- Where
- France
- Volunteers
- 320 people
- Sponsor
- Central Hospital, Nancy, France
Vaginoplasty, Gender Dysphoria, Adult
Can 3D Modeling Enhance Patient Understanding, Education, and Surgical Outcomes in Gender Affirming Peritoneal Vaginoplasty?
The project aims to address both clinical and relational gaps in transgender surgical care by improving understanding, communication, and outcomes through this novel integration of personalized 3D technology.
- Trial name
- 3D Modeling (NCT07412509)
- Testing
- Use 3D printed patient specific models for patient education
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Surgery, Larynx
Voice Outcome of Glottoplasty, Cricothyroid Approximation, Thyroplasty, and Chondrolaryngoplasty
The purpose of this study is to measure the short- and long-term voice outcome and outcome predictors of glottoplasty, cricothyroid approximation, thyroplasty, and chondrolaryngoplasty using a prospective non-randomized…
- Conditions
- Surgery, Larynx, Transgenderism, Gender Dysphoria
- Trial name
- NCT06439290
- Testing
- Phonosurgery, Mastectomy/breast augmentation
- Where
- 2 sites in Belgium
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University Ghent
PMDD, Stress
Stress & Premenstrual Symptoms Study
This study that aims to evaluate the psychophysiology of premenstrual mood disorders (PMDs) at baseline and after treatment with sertraline. Participants will include women with PMDs and healthy female controls.
- Conditions
- PMDD, Stress, Mood
- Trial name
- NCT02777372
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Gender Dysphoria
Patient Reported Outcome on Genital Sensitivity and Sexual Function After Genital Gender Affirming Surgery
For genital gender affirming surgery, it remains unclear to what extent genital sensitivity might be expected and what the impact of this might be on sexual functioning.
- Trial name
- PROGAS (NCT04993469)
- Testing
- Semmes-Weinstein monofilament testing and questionnaires
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Ghent
Premenstrual Dysphoric Disorder
Combined Effect of Tryptophan Rich Diet and Acupuncture on Depression Related to Premenstrual Dysphoric Disorder
Premenstrual Dysphoric Disorder (PMDD) is a severe form of premenstrual syndrome (PMS) affecting up to 8% of reproductive age women.
- Trial name
- NCT05813366
- Testing
- Acupuncture, Tryptophan-Rich Diet, Vitamin B6 Supplementation
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gender Dysphoria
Effects of Gender-affirming Hormone Therapy on Transgender People
This prospective cohort study aims to assess the impact of gender-affirming hormone therapy (GAHT) on transgender individuals' physical, psychological, social, and quality of life aspects.
- Trial name
- NCT06022562
- Where
- Taiwan
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- National Taiwan University
Transsexualism
GEnder Dysphoria Treatment in Sweden
Gender dysphoria (DSM-5) or transsexualism (ICD10) is a condition in which a person's feeling of gender identity is not congruent with the physical body.
- Trial name
- GETS (NCT02518009)
- Testing
- Genetic men treated with estrogen, Genetic women treated with androgen
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Hypogonadism, Gender Identity Dysphoria
The Effect of Sex Steroid Replacement Therapy in the Hypogonadism and Transgender Active-Duty Population
It has been known that both estrogen and testosterone are the major sex steroids regulating bone metabolism and other physiological changes in both male and female, respectively.
- Trial name
- NCT06247267
- Testing
- Fortesta, Estradiol
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center