Clinical trials: Dyspnea During Mechanical Ventilation
Acute Respiratory Failure
High Flow During Weaning From Mechanical Ventilation
Detection and relief of dyspnea in mechanically ventilated patients is a priority. Optimization of mechanical ventilation settings is unfortunately often insufficient to relieve dyspnea in patients entering the weaning process.
- Trial name
- FLOWEAN (NCT05577221)
- Testing
- High Flow Nasal Air
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity, Obesity With Complications
Prevalence, Determinants and Consequences of Dyspnea During Weaning in Critically Ill Obese Patients
ICU patients encounter numerous discomforts, with dyspnea (the sensation of breathlessness) being among the most distressing and impactful.
- Conditions
- Obesity, Obesity With Complications, Weaning From Mechanical Ventilation in Care Unit, Dyspnea
- Trial name
- WEAN OBESE (NCT06867354)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Respiratory Failure, Respiratory Insufficiency
HERMES: Quality and Safety of Advanced Respiratory Support During Patient Transport
The HERMES Phase III study is an international, multicenter, prospective observational investigation designed to characterize the quality and safety of patient transport during advanced respiratory support.
- Conditions
- Acute Respiratory Failure, Respiratory Insufficiency, Respiratory Distress, Critical Illness
- Trial name
- HERMES (NCT07805603)
- Testing
- Advanced Respiratory Support During Patient Transport
- Where
- 4 sites in Colombia, Egypt and 2 more
- Volunteers
- 565 people
- Sponsor
- Medipol University
Dyspnea During Mechanical Ventilation
Automatic Detection of Dyspnea in Mechanically Ventilated, Critically Ill Patients
The investigators will conduct a prospective, observational, two-center ICU study of 60 subjects on mechanical ventilation with respiratory failure of any cause.
- Trial name
- NCT07205952
- Where
- Argentina
- Volunteers
- 60 people
- Sponsor
- Hospital de Clinicas José de San Martín
Relationship Between Dyspnea and Ventilatory Variability
Respiratory Variability and Dyspnea During Spontaneous Breathing Trial
In intensive care unit, dyspnea, the distressing and fearful awareness of breathing, is frequent and harmful. To be treated, dyspnea must be detected and quantified, which is impossible in approximately 50% of patients receiving…
- Trial name
- DYSREVA (NCT05762614)
- Testing
- Dyspnea assessment
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dyspnea During Mechanical Ventilation, Inspiratory Effort
Association of Inspiratory Effort With Dyspnea During Assisted Mechanical Ventilation in Critically Ill Patients
During assisted mechanical ventilation, breathing results from the interaction between the patient and the ventilator. Optimal titration of pressure support is essential to maintain a balance between over-assistance and…
- Conditions
- Dyspnea During Mechanical Ventilation, Inspiratory Effort, Mechanical Ventilation
- Trial name
- NCT07877350
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- University of Crete
Hypoxic Respiratory Failure, Ventilators, Mechanical
Two Modes of Mechanical Ventilation for Intensive Care Patients With Low Blood Oxygen Due to Breathing Difficulties
The study examines individuals admitted to the intensive care unit due to breathing difficulties resulting in not getting enough oxygen into their bodies.
- Trial name
- NCT06140056
- Testing
- Airway pressure release ventilation, Volumen controlled mechanical ventilation
- Where
- 2 sites in Denmark
- Volunteers
- 45 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Dyspnea Invasive Mechanical Ventilation-associated
Dyspnea Facial Recognition During Weaning
Critically ill patients are exposed to many sources of discomfort and traumatic experiences, especially if they require invasive mechanical ventilation (IMV).
- Trial name
- DYS-FEREA (NCT05163275)
- Testing
- Video recording and EMG
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Failure, Dyspnea During Mechanical Ventilation
Mechanical Ventilator Adjustments and Patient Dyspnea
In the past 5 years, there are increasing data suggesting that patients treated with mechanical ventilation experience shortness of breath, despite appropriate sedation.
- Conditions
- Respiratory Failure, Dyspnea During Mechanical Ventilation, Mechanical Ventilation
- Trial name
- NCT07701850
- Testing
- Change to VC/AC, Change in Tidal Volume, Change in inspiratory flow
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Beth Israel Deaconess Medical Center
Dyspnea
Dyspnea and Cerebral Cortex Activation Measured by fNIRS During Spontaneous Breathing Trial
Background: In Intensive Care Unit (ICU) patients, dyspnea is frequent, severe and exerts unfavorable effects on the short, medium and long term. Detection and quantification rely on the patient's self-reporting abilities.
- Trial name
- WEANIRS (NCT06211738)
- Testing
- no intervention
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bronchiolitis, Respiratory Distress
Interest of Non Invasive Ventilation Versus Oxygen During the Intial Managment of Infant With Bronchiolitis
The purpose of the study is to evaluate, in a prospective way, the clinical, the manometric an gazometric benefit of non-invasive ventilation (VNI), (INFANTFLOW [EME, Brighton, England]) during bronchiolitis of the infant…
- Trial name
- NCT00513890
- Testing
- Infantflow [EME, Brighton, England]
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Montpellier