Clinical trials: Dyspnoea
COPD, Dyspnea
Hypnosis for the Management of Anxiety and Breathlessness During a Pulmonary Rehabilitation Program
Patients with chronic obstructive pulmonary disease (COPD) are prone to breathlessness, chest tightness and other anxiety-inducing symptoms.
- Conditions
- COPD, Dyspnea, Anxiety
- Trial name
- NCT04868357
- Testing
- Hypnosis, Relaxation
- Where
- France
- Volunteers
- 133 people
- Sponsor
- Centre Hospitalier de Bligny
Dyspnea
Feasibility and Accuracy of an Ultrasound Algorithm for Acute Dyspnea Diagnosis in the Emergency Department
The management of chest pain has revolutionized its prognosis, primarily by improving urgent diagnosis of myocardial infarction.
- Trial name
- EMERALD-US (NCT03691857)
- Testing
- Ultrasound algorithm (EMERALD-US)
- Where
- 7 sites in France
- Volunteers
- 225 people
- Sponsor
- CHOUIHED Tahar
Prematurity, Oxidative Injury
Comparison of Different Oxygen Delivery Strategies During Resuscitation of Babies
Preterm infants are born with immature lungs and often require help with breathing shortly after birth. This currently involves administering 100% oxygen.
- Conditions
- Prematurity, Oxidative Injury, Respiratory Distress
- Trial name
- NCT00356902
- Testing
- titration of oxygen during resuscitation
- Where
- Canada
- Volunteers
- 215 people
- Sponsor
- University of Calgary
Dyspnea
Clinician Assessment of Patient Dyspnea
Background: Dyspnea, like pain, is subjective and challenging to assess despite the large number of patients that report shortness of breath.
- Trial name
- NCT05319379
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Rush University Medical Center
Pneumonia
Validation of Thermal Imaging to Detect Pneumonia
The investigators are proposing a two-stage, prospective, cohort study of 138 subjects > 28 days old and < 18 years old with respiratory distress, already getting a chest x-ray as part of their routine clinical care, who will get…
- Trial name
- NCT03261479
- Testing
- Thermal image
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Massachusetts General Hospital
Chronic Obstructive Pulmonary Disease
Sensitivity of New Exercise Tests in Chronic Obstructive Pulmonary Disease (COPD)
This study was designed to test the following hypothesis: The 3-min constant rate step test and the 3-min constant rate shuttle walk test will be sensitive to detect improvement in exertional dyspnea following acute…
- Trial name
- NCT00807534
- Testing
- ipratropium bromide, constant rate step test, constant rate shuttle walk test
- Where
- 2 sites in Canada
- Volunteers
- 44 people
- Sponsor
- Laval University
Respiratory Distress, Pain
Management of Pain Respiratory Distress at the End of Life in Newborn Palliative Care in the Delivery Room
The newborn feels pain and the newborn at the end of life, in the delivery room, is potentially exposed to pain and respiratory distress.
- Trial name
- PALLI-ACC (NCT05220644)
- Testing
- Protocols for the management of end-of-life symptoms
- Where
- 4 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Asthma
Prevalence and Reversibility of Lung Hyperinflation in Asthma
The aim of this observational study is to evaluate the pulmonary hyperinflation and its immediate reversibility to a short acting beta2 agonist test in uncontrolled persistent asthmatic patients with dyspnea.
- Trial name
- Dist'air2 (NCT01573364)
- Where
- France
- Volunteers
- 450 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Smoking
Functional Capacity, Subjective Dyspnea and Fatigue in Smokers
Smoking remains a significant public health problem among the young adult population. Epidemiological studies in Turkey show a steadily decreasing age of smoking initiation and a remarkably high rate of smoking among…
- Trial name
- NCT07520981
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Istinye University
Dyspnea
Patient Dyspnea Under Veno-arterial Extracorporeal Circulation
Rationale: Patients with severe heart failure increasingly benefit from extracorporeal circulatory assistance (Extracorporeal Membrane Oxygenation - ECMO) that completely replaces the function of the heart and is in addition to…
- Trial name
- DYSCO2 (NCT04815330)
- Testing
- increment sweep gas flow, non-invasive ventilation
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Stroke
Robot-Assisted Rehabilitation in Individuals With Stroke
Stroke has a high rate of morbidity and mortality worldwide. This disease is the third leading cause of death after ischemic heart disease and cancer. Stroke is also the leading cause of disability in adults.
- Trial name
- NCT05550311
- Testing
- Robot-assisted rehabilitation, Conventional rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Biruni University
Cancer, Dyspnea, Paroxysmal
Fentanyl Buccal Tablet for the Relief of Episodic Breathlessness in Cancer Patients
"Episodic breathlessness (or dyspnea) is one form of chronic refractory breathlessness characterized by a severe worsening of breathlessness intensity or unpleasantness beyond usual fluctuations in the patient's perception.
- Trial name
- EFFENDYS (NCT04635852)
- Testing
- Fentanyl, Immediate release morphine
- Where
- 3 sites in Germany
- Volunteers
- 10 people
- Sponsor
- University of Cologne
Pulmonary Complications, Quality of Life
Theophylline in Treating Cancer Patients With Shortness of Breath
RATIONALE: Theophylline may help to relieve shortness of breath in patients who have cancer. It is not yet known whether theophylline is more effective than no further treatment for shortness of breath.
- Conditions
- Pulmonary Complications, Quality of Life, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00003684
- Testing
- theophylline, quality-of-life assessment
- Where
- 4 sites in Canada
- Volunteers
- 3 people
- Sponsor
- NCIC Clinical Trials Group
Percutaneous CORONARY INTERVENTION
Cardiac Rehabilitation With and Without Delorme Technique of Progressive Resisted Exercises in Patients of Post PCI.
To find the effect of cardiac rehabilitation program with and without progressive resisted exercises on patients after acute stage of PCI with at least 8 weeks history.
- Trial name
- NCT06460571
- Testing
- Standard Cardiac rehabilitation with Delorme technique, standard cardiac rehabilitation
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Dyspnea; Cardiac
Contribution and Reproducibility of Lung Ultrasound in the Diagnosis of Acute Heart Failure in the ED
Discrimination between cardiac and non-cardiac causes of dyspnea can be challenging, causing excessive delay before adequate therapy.
- Trial name
- NCT03660592
- Volunteers
- 1,024 people, healthy volunteers welcome
- Sponsor
- University of Monastir
COPD, Shortness of Breath
Comparison of Jacobson Relaxation Technique and Pranayama Technique in Patients With COPD
Comparison of Jacobson Relaxation Technique and Pranayama Technique in patients with COPD
- Conditions
- COPD, Shortness of Breath, Quality of Life, Cough
- Trial name
- NCT06463288
- Testing
- Jacobsons Breathing Technique, Pranayama Technique
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
COPD
Bronchodilators and Lung Mechanics During Exercise in COPD
Bronchodilators are medications that open the bronchi to help patients with COPD to breathe better. It is still not known exactly how this effect improves shortness of breath in people with COPD.
- Trial name
- SOUND (NCT06825013)
- Testing
- Bronchodilators inhalation
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Dr. J. Alberto Neder
Asthma, Heart Failure
The General Breathing Record Study
This study will test the use of a new handheld device (called the N-Tidal C), that measures a person's tidal breath carbon dioxide, in diagnosing the cause of someone's breathlessness.
- Conditions
- Asthma, Heart Failure, Pneumonia, Motor Neuron Disease
- Trial name
- GBRS (NCT03356288)
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TidalSense
Lung; Disease, Cystic Fibrosis
Evaluating Sensations of Breathlessness in Patients With Cystic Fibrosis
Shortness of breath (dyspnea) during exercise is a major source of distress and is a commonly reported symptom in patients with cystic fibrosis (CF).
- Conditions
- Lung; Disease, Cystic Fibrosis, Healthy
- Trial name
- CF_Dyspnea (NCT01799642)
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Asthma
Triple vs High Dose Inhaled CORticosteroids
Increase in inhaled corticosteroid dose vs triple therapy in T2-high asthma patients who remain uncontrolled with medium dose inhaled corticosteroids/long-acting β2 adrenergic combination: a real-life study.
- Trial name
- TRICORDA (NCT05919394)
- Testing
- To compare in both treatment arms the percentage of patients controlled at week 52.
- Where
- 17 sites in Spain
- Sponsor
- Galaxia Empírica
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