Clinical trials: Dyspnoea
Heart Failure
Pathophysiological Mechanisms of Activity-Related Dyspnea in Heart Failure: A Pilot Study
Dyspnea (breathlessness) on exertion is the most prevalent and distressing symptom of heart failure (HF). Nevertheless, the mechanisms of dyspnea in HF remain poorly understood.
- Trial name
- NCT02007486
- Testing
- Cardiopulmonary Exercise Testing
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- McGill University
Respiration Disorders
Impact of Positive End Maximum Voluntary Ventilation and Dyspnea Index in Patients After Valvular Heart Surgery
Pulmonary mechanics are further disturbed after cardiothoracic surgery that manifests like restrictive pathology, which may persist for weeks to months postoperatively.
- Trial name
- NCT05267067
- Testing
- respiratory exercises
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Postoperative Period, Lung Cancer (Diagnosis)
Investigation of the Effects of Tele-Yoga Training in Individuals With Lung Cancer Undergoing Lung Resection Surgery
This randomized controlled clinical trial aims to evaluate the effects of an 8-week tele-yoga intervention in individuals with lung cancer who have undergone lung resection surgery.
- Trial name
- NCT07001670
- Testing
- Tele-Yoga Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Dyspnea, Respiratory Distress Syndrome
LUng and Cardiac Ultrasound for REspiratory Distress in ElDerly
Prospective trial to evaluate the impact on the initial therapeutic inadequacy of a management strategy for acute dyspnea in the elderly based on the use of lung and cardiac ultrasonography.
- Trial name
- LUCREED (NCT06807983)
- Testing
- diagnostic strategy based on lung and cardiac ultrasonography
- Where
- France
- Volunteers
- 504 people
- Sponsor
- University Hospital, Toulouse
Dyspnea; Cardiac, Acute Disease
PAthwAy of Dyspneic patIent in Emergency (PArADIsE)
This is an observational retrospective single-center study (CHRU of Nancy) in patients cared for acute dyspnea by a medical team of the emergencies of the CHRU of Nancy.
- Trial name
- PArADIsE (NCT02800122)
- Where
- France
- Volunteers
- 24,000 people
- Sponsor
- CHOUIHED Tahar
Acute Respiratory Infections, Critical Illness in Children
Serum Vitamin D Status in Critically Ill Children With Acute Respiratory Infections
Acute respiratory infections (ARIs) are among the leading causes of hospitalization, morbidity, and mortality in children worldwide, particularly among critically ill patients admitted to pediatric intensive care units (PICUs).
- Conditions
- Acute Respiratory Infections, Critical Illness in Children, Vitamin D Deficiency, Pediatric Respiratory Infections
- Trial name
- VITD-ARI (NCT06547749)
- Testing
- Serum 25-Hydroxyvitamin D Assessment
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Assiut University
Post Covid-19 Respiratory, Dyspnea
The Effects of a Music Therapy Respiratory Protocol on Post-Covid-19 Respiratory Symptoms
The effects of a tested and published music therapy respiratory protocol shown to be efficacious with pediatric asthma and adult COPD is being studied with individuals living with post-Covid-19 respiratory symptoms.
- Conditions
- Post Covid-19 Respiratory, Dyspnea, SARS-CoV 2
- Trial name
- NCT05231512
- Testing
- Respiratory Music Therapy Protocol
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
COVID-19, Hyperventilation Syndrome
Relationship Between Hyperventilation Syndrome and SARS-CoV-2 Infection
Following an acute COVID-19 infection, many patients suffer from long lasting physical symptoms that may greatly impair quality of life.
- Trial name
- Hypercovid (NCT05224830)
- Testing
- Nijmegen questionnaire score
- Where
- France
- Volunteers
- 2,846 people
- Sponsor
- Central Hospital, Nancy, France
Dyspnea, Quality of Life
Gastric Sleeve-Induced Weight Loss on Shortness of Breath in Obesity
Most research to date on bariatric surgery outcomes has been about metabolic syndrome, a disorder very effectively treated by bariatric surgery.
- Trial name
- NCT05812183
- Testing
- Bariatric surgery, Medical weight loss
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Asthma, COPD
Exhaled Breath Metabolomic Biomarkers in the Acutely Breathless Patient
An acute study carried out across three acute admissions units within Leicestershire. The study is aimed at discovery and validation of volatile organic compounds (VOCs) in exhaled breath.
- Conditions
- Asthma, COPD, Heart Failure, Community-acquired Pneumonia
- Trial name
- EMBER (NCT03672994)
- Where
- United Kingdom
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Chronic Obstructive Pulmonary Disease
Tolerance of Surgical Masks in Chronic Respiratory Diseases
The study is conducted in the context of the COVID-19 pandemic in general, and more specifically in the context of the evaluation of the use of protective masks as a barrier to the spread of the virus.
- Trial name
- TOLMASK (NCT05454631)
- Testing
- surgical mask (5 different types)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Obstructive Pulmonary Disease
Combinaison of Virtual Reality and Rehabilitation to Improve Muscle Function, Exercise Tolerance, Exertional Symptoms and Dyspnea in Patients With Chronic Respiratory Disease: a Randomized Cross-over Trial
Chronic respiratory diseases, such as Chronic Obstructive Pulmonary Disease (COPD), are a leading cause of death globally. These diseases not only contribute significantly to mortality but also lead to a decline in physical…
- Trial name
- OVERMUSCLED (NCT06811402)
- Testing
- virtual reality
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Chronic Obstructive Pulmonary Disease
Effects of PEP on IC During IT in Patients With COPD
This study will investigate the effects of positive expiratory pressure (PEP) on hyperinflation in patients with chronic obstructive pulmonary disease (COPD). Inspiratory capacity (IC) is the primary outcome
- Trial name
- NCT03657082
- Testing
- PEP-10, PEP-1
- Where
- Belgium
- Volunteers
- 1 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Inhalation Therapy; Complications
The Effect of Stress Ball Utilisation on Treatment Duration, Dyspnea Severity and Anxiety Level in Nebuliser Therapy
Nebul Therapy is very effective in quickly improving the symptoms of respiratory system diseases. While applying this treatment, patients are expected to complete a sufficient period of time.
- Trial name
- NCT06297356
- Testing
- Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Respiratory Distress
The Smell of Breast Milk and Therapeutic Positions in Comfort
Before starting the data collection process, a pilot study was conducted with 10 preterm newborns, five in the safe swaddling group and five in the control group, to evaluate the comprehensibility of the questionnaire form and…
- Trial name
- NCT06826053
- Testing
- Therapeutic position, Therapeutic position + smell breast milk
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Karamanoğlu Mehmetbey University
Asthma, Dyspnea
SU JOK THERAPY TO IMPROVE DYSPNEA AND INSOMNIA IN ASTHMA
Asthma is a long-term lung disease that can make breathing difficult and can also affect sleep. Even with regular medical treatment, many people with asthma continue to experience shortness of breath and insomnia.
- Conditions
- Asthma, Dyspnea, Insomnia
- Trial name
- SUJOK-ASTHMA (NCT07746570)
- Testing
- su jok therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Dyspnea, Congestive Heart Failure
Comparison Between Lung Ultrasound and Chest Radiography for Acute Dyspnea
For patients presenting to the Emergency Department with acute dyspnea, emergency physicians will be asked to categorize the diagnosis as acute decompensated heart failure or non-cardiogenic shortness of breath a) after the…
- Trial name
- NCT02105207
- Testing
- Lung Ultrasound, Chest Radiography
- Where
- 2 sites in Italy
- Volunteers
- 530 people
- Sponsor
- University of Turin, Italy
Dyspnea, Respiratory Insufficiency
Cognitive and Behavioral Intervention for the Management of Episodic Breathlessness in Patients With Advanced Disease
Episodic breathlessness is a common and distressing symptom in patients with advanced disease such as cancer, chronic obstructive pulmonary disease (COPD) and chronic heart failure.
- Conditions
- Dyspnea, Respiratory Insufficiency, Neoplasms, Pulmonary Disease, Chronic Obstructive
- Trial name
- CoBeMEB (NCT04630743)
- Testing
- Cognitive and Behavioral intervention for the Management of Episodic Breathlessness
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- University of Cologne
Chronic Heart Failure, Heart Decompensation
Early-start Exercise Training in Subacute Heart Failure
The purpose of this study is to evaluate the feasibility and the short-term effects of an early-start aerobic exercise training program on functional capacity, symptoms and neurohormonal activation in chronic heart failure…
- Trial name
- RE-START (NCT02051985)
- Testing
- Aerobic exercise training, Standard physical therapy
- Where
- 9 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Salvatore Maugeri
Dyspnea, Chronic Obstructive Pulmonary Disease
Menthol for Dyspnea Relief in Health and COPD
Menthol inhalation (MI) is a novel and promising treatment option for acute relief of dyspnea, however, the underlying ventilatory and/or neural related mechanisms for this relief in symptoms remain unknown.
- Trial name
- MENTHODYSC (NCT05785026)
- Testing
- Menthol inhalation, Strawberry scent, Menthol inhalation and facial airflow
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- KU Leuven
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