Clinical trials: Dyspnoea
COPD, Obesity
Effects of Obesity on COPD
The purpose of this study is to investigate whether obese COPD patients experience more or less discomfort in daily life. Furthermore the investigators will evaluate if body composition or body fat distribution has effects on…
- Conditions
- COPD, Obesity, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT06474858
- Where
- Netherlands
- Volunteers
- 166 people
- Sponsor
- Rijnstate Hospital
Pneumonia, Dyspnea
The Effects of Wintergreen Essential Oil Inhalation on Alleviating Dyspnea Among Patients With Pneumonia
Pneumonia is a major public health concern globally and domestically. Dyspnea experienced by hospitalized pneumonia patients often induces anxiety and psychological distress.
- Trial name
- NCT07894835
- Testing
- Sunflower oil inhalation, 1% Linalool inhalation, Wintergreen essential oil inhalation
- Where
- Taiwan
- Volunteers
- 84 people
- Sponsor
- Far Eastern Memorial Hospital
MINOCA, Shortness of Breath
Determinants of Cardiorespiratory Fitness and Effects of HIIT in Patients With ANOCA Obstructive Coronary Artery Disease(ANOCA)
The main goal is to understand what causes reduced fitness in ANOCA and whether targeted exercise can help improve it. This study aims to better understand why patients with Angina and No Obstructive Coronary Artery Disease…
- Conditions
- MINOCA, Shortness of Breath, Atherosclerotic Heart Disease of Native Coronary Artery
- Trial name
- NCT07182955
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Virginia
COPD
Breathing Control in Patients With Chronic Obstructive Pulmonary Disease (COPD)
There is a demand for explorative and comparative studies on various non-pharmaceutical efforts in treating and helping chronic obstructive pulmonary disease patients. This study has been developed in light of this need.
- Trial name
- NCT01512043
- Testing
- Breathing control
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Lovisenberg Diakonale Hospital
Bronchiolectasis
PEP Breathing Versus Incentive Spirometry on Dyspnea and Sputum Profile in Bronchiolectasis Patients
Bronchiolectasis is the manifestation of chronic bronchitis characterized by saccular dilatation of the terminal bronchioles \& bronchiectasis refers to abnormal dilatation of the bronchi.
- Trial name
- NCT05719597
- Testing
- PEP (Positive Expiratory Pressure), IS (Incentive spirometry)
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease, Dyspnea
A Wearable In-phase Chest Wall Vibration Device for Relief of Dyspnoea in COPD: a First-in-human Exploratory Study
The goal of this exploratory clinical trial is to evaluate the initial clinical safety and performance of a prototype wearable chest wall vibration (CWV) device intended to relieve exertional dyspnea in adults with Chronic…
- Trial name
- ResWave (NCT06432920)
- Testing
- ResWave
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- Elevre Medical Ltd.
Vascular Filling, Newborn
Impact of Prepartum Intravenous Fluid Intake on Newborn Weight Loss in the First Days of Life
At birth, the infant's weight was measured daily to assess the adequacy of nutritional intake. This indicator can be influenced by various factors related to the mother, her pregnancy, as well as medical interventions during the…
- Conditions
- Vascular Filling, Newborn, Weight Loss, Jaundice
- Trial name
- PERLE (NCT07243054)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Shortness of Breath, Asthma in Children
The Effect of Nebulized Epinephrine in Asthma Exacerbation in Pediatric Age Group With the Standard Treatment Compared to Standard Treatment Using Improvement PRAM Score as a Primary Outcome
Our study aiming to look in improvement of Pediatric Respiratory Assessment Measure (PRAM) score as a primary outcome. The secondary outcomes involving the need for second step management, need for admission and possible side…
- Conditions
- Shortness of Breath, Asthma in Children, Epinephrine Causing Adverse Effects in Therapeutic Use, Salbutamol Adverse Reaction
- Trial name
- NCT05667727
- Testing
- nebulized epinephrine, Salbutamol
- Where
- Oman
- Volunteers
- 30 people
- Sponsor
- Oman Medical Speciality Board
Chronic Obstructive Pulmonary Disease
Basic Body Awareness Therapy (BBAT) for Patients With Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a burden to health care and economic systems globally, to manage this preventable and treatable disease, different pharmacological and non-pharmacological interventions were shown…
- Trial name
- NCT05506202
- Testing
- Individual basic body awareness therapy, Respiratory physiotherapy interventions
- Where
- Hong Kong
- Volunteers
- 25 people
- Sponsor
- North District Hospital
COPD Exacerbation, Dyspnea
Palliation of Dyspnea With Mouth Piece Ventilation in AECOPD
An uncontrolled feasibility study on using mouth piece ventilation in palliation of dyspnea in subjects with acute exacerbation of COPD without acute hypercapnic respiratory failure.
- Trial name
- NCT03025425
- Testing
- Trilogy 100 ® (Philips Respironics)
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Tampere University Hospital
Tachycardia, Dyspnea
Post-Acute Sequelae of Coronavirus-19 (COVID-19) With Dyspnea on Exertion And Associated TaChycardia TrEatment Study
Most patients with acute COVID-19 (Coronavirus 19) recover within weeks, however a significant number of individuals will develop the post-acute COVID 19 syndrome (PASC).
- Conditions
- Tachycardia, Dyspnea, COVID-19
- Trial name
- PEACE (NCT05096884)
- Testing
- Metoprolol Succinate
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Hackensack Meridian Health
Dyspnea
Pilot Randomized Controlled Trial of a Breathlessness Intervention Service for Chronic Obstructive Pulmonary Disease
The aim of this study is to test the feasibility of conducting a pragmatic fast track Randomized Controlled Trial (RCT) of the Breathlessness Intervention Service (BIS) versus standard care for patients with COPD and their…
- Trial name
- BIS-PhIInm (NCT00711438)
- Testing
- Breathlessness Intervention Service (BIS), Best supportive care (Standard care)
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Allergy, Respiratory Distress
Primary Allergy and Its Impact on the Occurrence of Respiratory Distress in Infants at 12 Months of Age
The number of people with allergies has been steadily increasing over the years. Symptoms in infants, such as bronchiolitis, gastroesophageal reflux, eczema, or atopic dermatitis, can be early warning signs of allergies in…
- Conditions
- Allergy, Respiratory Distress, Atopic Manifestations, Immediate Postnatal Parameters
- Trial name
- AIRE (NCT07832643)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 508 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Post COVID-19 Condition (PCC), Dysfunctional Breathing
Dysfunctional Breathing in Post COVID-19 Condition.
The goal of this observational study with a cross-sectional design is to investigate what signs, symptoms and assessment which can describe and explain dysfunctional breathing in patients with post COVID-19 condition.
- Conditions
- Post COVID-19 Condition (PCC), Dysfunctional Breathing, Breathing Pattern Disorder, Post-Acute COVID-19 Syndrome
- Trial name
- DB-PCC (NCT06776263)
- Where
- 2 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Lung Cancer
Reducing Lung Cancer-Related Anxiety (RELAX)
The purpose of this research study is to compare the effects of music and different levels of device-guided breathing on anxiety and shortness of breath in lung cancer survivors.
- Trial name
- RELAX (NCT02063828)
- Testing
- Group A - Device guided breathing low dose, Group B - Device guided breathing high dose, Group C - Usual Breathing Control Group
- Where
- 11 sites in United States
- Volunteers
- 46 people
- Sponsor
- Wake Forest University Health Sciences
Advanced Cancers, Hematologic Disorder
Dexamethasone Dyspnea Study
The goal of this clinical research study is to learn if dexamethasone can help reduce shortness of breath in cancer patients. Researchers also want to learn if it can help to improve lung function and quality of life.
- Conditions
- Advanced Cancers, Hematologic Disorder, Solid Tumors
- Trial name
- NCT01670097
- Testing
- Dexamethasone, Questionnaires, Spirometer
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- M.D. Anderson Cancer Center
Dyspnea
Dyspnea and Cerebral Cortex Activation Measured by fNIRS During Spontaneous Breathing Trial
Background: In Intensive Care Unit (ICU) patients, dyspnea is frequent, severe and exerts unfavorable effects on the short, medium and long term. Detection and quantification rely on the patient's self-reporting abilities.
- Trial name
- WEANIRS (NCT06211738)
- Testing
- no intervention
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COPD, Interstitial Lung Disease
Anxiety Management in Breathlessness.
The goal of this mixed methods study is to learn about cranial electrotherapy stimulation (CES) using Alpha-Stim AID in anxiety related to breathlessness in advanced lung diseases.
- Trial name
- NCT06066658
- Testing
- cranial electrotherapy stimulation (Alpha-Stim AID)
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Leicester
COPD, Hypoxia
Automated Oxygen Administration -Rethinking Interventions Alleviating Dyspnea in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is associated with high morbidity and mortality. The Danish Lung Association estimates that 320,000 Danes live with COPD, of which approximately 50,000 with severe COPD.
- Conditions
- COPD, Hypoxia, Closed-Loop Communication, Dyspnea
- Trial name
- NCT04370990
- Testing
- O2matic
- Where
- 5 sites in Denmark
- Volunteers
- 157 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Bronchodilators in Mild Chronic Obstructive Pulmonary Disease (COPD)
In people with mild COPD, the ability to exhale air from the lungs is partly limited because of narrowing and collapse of the airways.
- Trial name
- NCT00202176
- Testing
- Ipratropium Bromide
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Queen's University
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