Clinical trials: Dyspnoea
Cancer (With or Without Metastasis), Interstitial Lung Disease (ILD)
Hypnosis on Breathlessness Mastery in Patients With Persistent Dyspnea
Persistent dyspnea is a debilitating symptom, that is common and difficult to treat. This symptom is found in many different diseases including chronic obstructive pulmonary disease (COPD), interstitial lung disease (ILD)…
- Conditions
- Cancer (With or Without Metastasis), Interstitial Lung Disease (ILD), Chronic Heart Failure (CHF), COPD
- Trial name
- HYPNEA (NCT07173348)
- Testing
- Hypnosis
- Where
- Switzerland
- Volunteers
- 82 people
- Sponsor
- University Hospital, Geneva
Chronic Obstructive Pulmonary Disease
Nurse Managed Sequential Strength Training and Bicycle Training in Chronic Obstructive Pulmonary Disease (COPD)
This is a 16 week exercise training program for people with severe to very severe chronic obstructive pulmonary disease (COPD). The purpose of this study is to find out if performing strength training prior to initiating exercise…
- Trial name
- NCT01058213
- Testing
- Resistance training, Aerobic training
- Where
- United States
- Volunteers
- 354 people
- Sponsor
- University of Illinois Chicago
Respiratory Failure
Photoplethysmographic Scaling of Dyspnoea
Timely prediction of impending respiratory failure is vital, yet relies on subjective clinical assessment of the patient's respiratory status.
- Trial name
- DYSPO (NCT04582838)
- Testing
- Pulse oximeter, ECG
- Where
- 2 sites in Romania
- Volunteers
- 60 people
- Sponsor
- Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu
COVID-19 Pandemic, Diabetes
Study on the Effect of Incentive Spirometer-based Respiratory Training on the Long COVID-19
The COVID-19 pandemic has emerged as the most significant public health crisis of the 21st century. As of the end of January 2023, global confirmed cases have exceeded 670 million, with a domestic cumulative total of 10.24…
- Conditions
- COVID-19 Pandemic, Diabetes, Hypertension, Cardiac Disease
- Trial name
- NCT06231225
- Testing
- Incentive Spirometer respiratory training
- Volunteers
- 100 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Bronchiectasis
Effects of Energy Conservation Techniques With Pursed Lip Breathing on Quality of Life in Bronchiectasis
Bronchiectasis is the abnormal dilatation of the bronchi. Due to airway dilatation patient is unable to clear the mucus and risk of infection is increased.
- Trial name
- NCT06995989
- Testing
- energy conservation techniques with pursed lip breathing, pursed lip breathing
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Pulmonary Disease, Chronic Obstructive (COPD)
Additional Effects of Box Breathing Technique With Short Term Pulmonary Rehabilitation on Dyspnea and Functional Capacity in Patients With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease is progressive and irreversible respiratory condition characterized by persistent airflow limitation leading to dyspnea and reduced functional capacity.
- Trial name
- NCT07518472
- Testing
- Short term Pulmonary Rehabilitation, Box breathing with short term pulmonary rehabilitation
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Lung; Disease, Cystic Fibrosis
Evaluating Sensations of Breathlessness in Patients With Cystic Fibrosis
Shortness of breath (dyspnea) during exercise is a major source of distress and is a commonly reported symptom in patients with cystic fibrosis (CF).
- Conditions
- Lung; Disease, Cystic Fibrosis, Healthy
- Trial name
- CF_Dyspnea (NCT01799642)
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Post-Acute COVID-19, Post-Acute COVID-19 Syndrome
Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program for PASC Program to Improve Functioning of Persons Suffering From Post-COVID-19 Syndrome: A Randomized Controlled Trial
About 10-20% of persons who contract SARS CoV-2 will experience persistent post-acute sequelae of SARSCoV-2 infection (referred here as PASC).
- Conditions
- Post-Acute COVID-19, Post-Acute COVID-19 Syndrome, Post-Acute COVID-19 Infection, Long COVID
- Trial name
- NCT06156202
- Testing
- Comprehensive Rehabilitation, Augmented Usual Care
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Pennsylvania
Dyspnea, Quality of Life
STRETCH OF RESPIRATORY MUSCLES IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
THE AIM OF THIS STUDY IS TO TEST IF THE STRETCHING OF THE RESPIRATORY ACCESSORY MUSCLE PROVIDE SOME BENEFIT ON THORACOABDOMINAL MECHANICS, FUNCTIONAL CAPACITY, PSYCHOLOGICAL AND SOCIAL ASPECTS IN PATIENTS WITH CHRONIC OBSTRUCTIVE…
- Conditions
- Dyspnea, Quality of Life, Respiratory Symptoms
- Trial name
- NCT02036762
- Testing
- Stretching Exercises
- Where
- 3 sites in Brazil
- Volunteers
- 24 people
- Sponsor
- University of Sao Paulo
Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis)
Music Therapy Protocol to Support Bulbar and Respiratory Functions in ALS
This study evaluates potential of music therapy treatment to support breathing, speech, swallow and cough of persons with amyotrophic lateral sclerosis (ALS).
- Conditions
- Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis), Dysarthria, Flaccid, Dysarthria, Spastic
- Trial name
- NCT03604822
- Testing
- Music therapy
- Where
- 2 sites in Russia, United Kingdom
- Volunteers
- 8 people
- Sponsor
- Alisa Apreleva
Dyspnea, Respiratory Rate
Evaluating the Effectiveness of Incentive Spirometry
Post-operative pulmonary complications (PPCs) have a major impact on patients and healthcare expenses. The goal of perioperative respiratory therapy is to improve airway clearance, increase lung volume, and mitigate atelectasis.
- Conditions
- Dyspnea, Respiratory Rate, Oxygen Saturation, Oxygen Requirements
- Trial name
- NCT02952027
- Testing
- Use-recording, patient-reminder alarm for incentive spirometry
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Lifespan
Acute Dyspnea
PAthwAy of Dyspneic patIent in Emergency in France
This observational retrospective multi-center study focuses on patients treated for acute dyspnea by emergency medical teams. The primary objective is to identify factors associated with the risk of mortality and…
- Trial name
- Fr-PArADIse (NCT06509854)
- Where
- 4 sites in France
- Volunteers
- 89,700 people
- Sponsor
- Pr. Nicolas GIRERD
Chronic Obstructive Pulmonary Disease (COPD)
129-Xe MRI Study of Single Triple Therapy Inhaler Effects in COPD Patients With Moderate-severe Dyspnea and/or Poor Health Status With High or Low Risk of Exacerbation
The goal of this study is to study how 12-weeks daily (and optional 48-weeks) single inhaler triple therapy (fluticasone furoate (FF)-an inhaled corticosteroid; umeclidinium (UMEC)-a long-acting muscarinic antagonist; vilanterol…
- Trial name
- MUST (NCT07192016)
- Testing
- fluticasone furoate(FF)/umeclidinium (UMEC)/vilanterol(VI) (100/62.5/25) mcg
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Western University, Canada
Asthma
Effects of Liuzijue Exercise Versus Tai Chi Chuan Exercise in Asthma
To analyze either Liuzijue exercise or Tai Chi Chuan exercise is effective in improving dyspnea index and pulmonary function in patients with asthma.
- Trial name
- NCT06426849
- Testing
- Liuzijue Exercise, Tai Chi Chuan Exercise
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease
Icing and Airflow Stimulation in Obstructive Lung Diseases
A randomized controlled trial in which icing and airflow stimulation for reduction of dyspnea in patients of obstructive lung disease was done which is characterized as condition of infection described by constant improvement of…
- Trial name
- NCT03887364
- Testing
- Group A-Diaphragmatic breathing, Group B-Icing and Airflow Stimulation
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Riphah International University
Lung Cancer
The Effect of Mindfulness-Based Breathing Exercises on Dyspnea, Symptom Control, and Quality of Life in Lung Cancer Patients Undergoing Chemotherapy
This research is designed to determine the effect of mindfulness-based breathing exercises on dyspnea, symptom control, and quality of life in lung cancer patients undergoing chemotherapy.
- Trial name
- NCT07520799
- Testing
- Mindfulness-Based Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Firat University
Idiopathic Pulmonary Fibrosis
Dose-Escalation Study of Artesunate Patients With IPF
Idiopathic Pulmonary Fibrosis (IPF) is a chronic progressive fibrotic lung disease resulting in increasing shortness of breath, cough, and low oxygen levels as a result of lung tissue scarring .
- Trial name
- SAFE-IPF (NCT05988463)
- Testing
- Artesuante
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Joseph C. Wu
Chronic Obstructive Pulmonary Disease
The Role of Substance P on Perception of Breathlessness During Resistive Load Breathing
Substance P is released from sensory nerves and transmits pain information into the central nervous system. As pain and dyspnea share many characteristics, including similar neurological pathways, it is possible that substance P…
- Trial name
- SP-RLB (NCT01580423)
- Testing
- aprepitant
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Hypoxia, Respiratory Distress
Advancement of Modified Bubble CPAP
This study proposes that modifying the current form of bCPAP by adjusting the nasal prongs to fit older children, will create a safe form of respiratory support that may help to decrease respiratory distress and thus mortality…
- Trial name
- NCT02208323
- Testing
- Bubble CPAP
- Where
- Uganda
- Volunteers
- 87 people
- Sponsor
- University of Minnesota
Lung Cancer
Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer
This research study is evaluating a behavioral intervention designed to help people with advanced lung cancer manage dyspnea (i.e., breathlessness or shortness-of-breath).
- Trial name
- NCT03089125
- Testing
- Dyspnea Intervention, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 247 people
- Sponsor
- Massachusetts General Hospital
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