Clinical trials: Dyspnoea
Chronic Obstructive Pulmonary Disease
Muscle Energy Techniques in COPD Patients
Patients diagnosed with COPD as a result of hyperinflation adapt to the increased workload through shortening and overactivation of other muscles because of their dual function as muscles of the upper limb and neck motion which…
- Trial name
- NCT04773860
- Testing
- Muscle Energy Techniques
- Volunteers
- 110 people
- Sponsor
- University of Malta
Acute Dyspnoea
Comparison of CXR and MnDCT
A comparison of chest x-ray (CXR) and Minimum dose CT (MnDCT) in the acutely ill patient. The hypothesis is that MnDCT is more sensitive than CXR in the detection of acute findings in the acutely ill patient.
- Trial name
- NCT00188435
- Testing
- Minimum Dose CT
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Acute Respiratory Distress Syndrome
Effect of PEEP Titration on the EELV Measured by the Nitrogen Dilution Technique in ARDS
Mechanical ventilation of the patient with acute respiratory distress syndrome is one of the first therapies.
- Trial name
- TIPEX-VOLTEX (NCT04352725)
- Testing
- End-expiratory lung volume measurement and incremental PEEP titration
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Intercommunal Aix-Pertuis
Dyspnea, Heart Failure
Registry of Patients With Acute Dyspnea in the Emergency Department
This is a prospective registry of patients presenting with acute dyspnea to the emergency department of the city hospital in Nuremberg.
- Conditions
- Dyspnea, Heart Failure, COPD
- Trial name
- NCT01910233
- Where
- Germany
- Volunteers
- 947 people
- Sponsor
- Klinikum Nürnberg
Thoracic Discopathy, Back Pain
Physiotherapy in Thoracic Discopathy
Background and Objective: Information regarding the effects of physiotherapy on quality of life and alterations in pulmonary function tests among patients with thoracic discopathy is notably limited in the literature.
- Conditions
- Thoracic Discopathy, Back Pain, Respiratory Dysfunction
- Trial name
- NCT07749248
- Testing
- Traditional Physiotherapy, Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Breathlessness, Quality of Life
Structured Exercise Training Programme in Idiopathic Pulmonary Fibrosis
In this single centre non-randomised pilot cohort study we wish to quantify the effect of a twice weekly, 8 week, structured responsive exercise training programme on exercise tolerance, symptoms and health related quality of…
- Conditions
- Breathlessness, Quality of Life, Idiopathic Pulmonary Fibrosis
- Trial name
- Rehab-IPF (NCT03222648)
- Testing
- Structured Responsive Exercise Training, Usual Care
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Work of Breathing
The Role of Breathing Perception in Respiratory Control
Warfighters are frequently exposed to environments and life-support systems that increase breathing resistance and the work of breathing (WOB), such as aircraft on-board oxygen generation systems and underwater breathing…
- Trial name
- NCT07470099
- Testing
- Ambient Noise, Increased Auditory Feedback, Noise Distraction
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Indiana University
Hypertension, Diabete Mellitus
Assessing the Effectiveness of Large Language Model (LLM)-Enabled Nurse Treatment Planning in 2 Indian Districts
The goal of this clinical trial is to learn whether AI-enabled, nurse-led treatment planning can improve the quality of clinical reasoning and management compared with standard physician-led care in adult primary care patients…
- Conditions
- Hypertension, Diabete Mellitus, Breathlessness, Fever
- Trial name
- NCT07432893
- Testing
- AI-enabled clinical decision support tool (software) used by nurses, Physician consultation
- Where
- 2 sites in India
- Volunteers
- 736 people
- Sponsor
- Sarah Nabia
Covid19, Dyspnea
Understanding Exertional Dyspnea and Exercise Intolerance in COVID-19
A novel corona virus emerged in 2019 causing Corona Virus Disease 2019 (covid-19). In one year more than 80 000 000 cases worldwide were documented.
- Trial name
- NCT04732663
- Testing
- No Intervention
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Acute Respiratory Failure
High Flow During Weaning From Mechanical Ventilation
Detection and relief of dyspnea in mechanically ventilated patients is a priority. Optimization of mechanical ventilation settings is unfortunately often insufficient to relieve dyspnea in patients entering the weaning process.
- Trial name
- FLOWEAN (NCT05577221)
- Testing
- High Flow Nasal Air
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alpha 1-antitrypsin Deficiency (AATD)
Screening for Alpha-1 Antitrypsin Deficiency in Patients With Airway Obstruction
Brief Summary: This study aims to find out if a genetic condition called Alpha-1 Antitrypsin Deficiency (AATD) is more common in people who have shortness of breath and signs of airway obstruction on their breathing tests.
- Trial name
- AATD-SAO (NCT07152834)
- Testing
- Blood Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 734 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
COPD, Chronic Obstructive Pulmonary Disease
Melodica Orchestra for Dyspnea: Safety and Feasibility Pilot
This project seeks to pilot-test the feasibility of using a melodica training program to teach pursed lip breathing for Veterans with chronic obstructive pulmonary disease (COPD) with moderate to severe dyspnea (shortness of…
- Conditions
- COPD, Chronic Obstructive Pulmonary Disease, Dyspnea, Breathlessness
- Trial name
- MELODY (NCT03653104)
- Testing
- Melodica Intervention, Pulmonary Health Education
- Where
- United States
- Sponsor
- VA Quality Enhancement Research Intiative
Bronchiectasis Adult, Yoga
Effects of an Online Yoga Program on Exercise Capacity and Quality of Life in Bronchiectasis Patients
Bronchiectasis is a chronic lung disease characterized by persistent cough, sputum production, shortness of breath, and recurrent infections, which can reduce physical capacity and quality of life.
- Trial name
- YOGA-BR (NCT07540936)
- Testing
- Yoga Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul Medipol University Hospital
Acute Disease, Sepsis
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care.
- Conditions
- Acute Disease, Sepsis, Pneumonia, Frailty
- Trial name
- Acutelines (NCT04615065)
- Where
- Netherlands
- Volunteers
- 35,000 people
- Sponsor
- University Medical Center Groningen
Post-Acute COVID19 Syndrome, Long COVID
Exercise Intervention Using mHealth in Patients With Post-Acute COVID-19 Syndrome: a Randomized Clinical Trial
Post-Acute Syndrome COVID-19 is a disease resulting from infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Conditions
- Post-Acute COVID19 Syndrome, Long COVID, Post COVID-19 Condition
- Trial name
- COVIDReApp (NCT05725538)
- Testing
- COVIDReApp Group, Control Group
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Cadiz
Chronic Obstructive Pulmonary Disease
The Effectiveness of an Innovative Inhalation Training Device in Improving Medication Accuracy, Dyspnea, and Quality of Life in Elderly Patients With Chronic Obstructive Pulmonary Disease
This study aims to evaluate the effectiveness of an innovative inhaler training device, "Golden Rhino" (pMDI Practice Tool), in improving inhalation technique accuracy, dyspnea severity, and quality of life among elderly patients…
- Trial name
- pMDII (NCT07305649)
- Testing
- Innovative Inhaler Training Device (金犀利), Standard pMDI Inhaler Education
- Where
- Taiwan
- Volunteers
- 82 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Acute Respiratory Distress Syndrome, Corona Virus Infection
Knowledge, Attitude and Practice of Dental Students About COVID-19
Coronavirus disease 2019 (abbreviated "COVID- 19") is a pandemic respiratory disease that is caused by a novel coronavirus and was first detected in December 2019 in Wuhan, China.
- Conditions
- Acute Respiratory Distress Syndrome, Corona Virus Infection, Acute Lung Injury, Fever
- Trial name
- NCT04449081
- Testing
- Knowledge, Attitude, Practice, Awareness, Preference
- Where
- Malaysia
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Interstitial Lung Disease
Nebulized Fentanyl in Patients With Mild to Moderate Interstitial Lung Disease and Chronic Dyspnea
Patients with interstitial lung disease (ILD) experience distressing activity-related respiratory discomfort which is challenging to manage therapeutically.
- Trial name
- NCT03018756
- Testing
- Fentanyl Citrate
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Dr. Denis O'Donnell
COVID-19
Effectiveness of Exercise and Physical Activity in Individuals.
The effects of breathing exercises and physical activity counseling applied for 4 weeks on the number of daily steps, dyspnea, pain, fatigue, mood and quality of life in individuals who have just had COVID-19 are not yet known.
- Trial name
- NCT07000331
- Testing
- Thoracic expansion exercises, Physical activity counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Gulsah Bargi
Dyspnea
Feasibility and Accuracy of an Ultrasound Algorithm for Acute Dyspnea Diagnosis in the Emergency Department
The management of chest pain has revolutionized its prognosis, primarily by improving urgent diagnosis of myocardial infarction.
- Trial name
- EMERALD-US (NCT03691857)
- Testing
- Ultrasound algorithm (EMERALD-US)
- Where
- 7 sites in France
- Volunteers
- 225 people
- Sponsor
- CHOUIHED Tahar
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