Clinical trials: Dysthymic Disorder
Depression, Dysthymia
Cognitive Behavioral Therapy (REBT/CBT) Evaluation for Dysthymia in the Practice of Clinical Social Work at Primary Care
Introduction: Minor psychiatric disorders are important in primary care, because of its high prevalence and consumption of healthcare resources generated.
- Conditions
- Depression, Dysthymia, Ambulatory Health Services
- Trial name
- NCT02112708
- Testing
- Rational-Emotive-Behavioral Therapy, Control Group usual care
- Where
- Spain
- Volunteers
- 129 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Depression, End Stage Renal Disease
A Trial of Sertraline vs. CBT for End-stage Renal Disease Patients With Depression {ASCEND}
Patients whose kidneys fail generally require dialysis treatments to sustain life. The ability of patients to make major adjustments in their lives for dialysis is hampered by depression that affects almost one-quarter of such…
- Trial name
- ASCEND (NCT02358343)
- Testing
- Engagement Interview, Cognitive Behavioral Therapy, Antidepressant Drug Therapy
- Where
- 3 sites in United States
- Volunteers
- 184 people
- Sponsor
- University of Washington
Depression, Mild Cognitive Impairment
Combination Treatment Study for Memory Impairment and Depression
Patients presenting with depression (DEP) and cognitive impairment (CI), represent a unique, understudied population that is difficult to diagnose, treat and estimate prognosis.
- Trial name
- DEP-CI (NCT01658228)
- Testing
- Donepezil, Citalopram, Venlafaxine
- Where
- 2 sites in United States
- Volunteers
- 86 people
- Sponsor
- New York State Psychiatric Institute
Major Depressive Disorder, Dysthymia
Dichotic Listening as a Predictor of Medication Response in Depression
This study will recruit 100 depressed patients to test whether the previous finding of an association between treatment response (with treatment groups including placebo, imipramine, and fluoxetine) and preferences of hemispheric…
- Trial name
- NCT00404755
- Testing
- escitalopram, bupropion, imipramine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- New York State Psychiatric Institute
Major Depressive Disorder, Dysthymic Disorder
Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older Adults
The goal of this open-administration treatment study of citalopram (or duloxetine) is to evaluate the effect of antidepressant medication on treating the syndrome of "frailty" in older adults with depressive symptoms.
- Conditions
- Major Depressive Disorder, Dysthymic Disorder, Depressive Disorder, NOS
- Trial name
- NCT01973283
- Testing
- Antidepressant Medication
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- New York State Psychiatric Institute
Dysthymic Disorder
Wellbutrin XL for Dysthymic Disorder
This is a ten-week, double-blind study of Wellbutrin XL in outpatients with dysthymic disorder, a form of low-grade chronic depression.
- Trial name
- NCT00225251
- Testing
- bupropion XL
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Depression, Bipolar, Depression, Unipolar
Pramipexole to Target "Anhedonic Depression"
The heterogeneity of depression suggests that different neurocircuits and pathophysiological mechanisms are involved. Anhedonia - the inability to experience pleasure from, or the lack of motivation to carry out, usually…
- Conditions
- Depression, Bipolar, Depression, Unipolar, Dysthymia, Anhedonia
- Trial name
- PILOT-PRAXOL (NCT04121091)
- Testing
- Pramipexole Pill
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Region Skane
Major Depressive Disorder, Dysthymic Disorder
Cognitive Therapy for Unipolar Depression: Efficacy of a Dilemma-Focused Intervention
The purpose of this study is to determine the efficacy of a brief psychological intervention focused on the personal dilemmas identified for each depressive patient.
- Trial name
- NCT01542957
- Testing
- Combined Cognitive Behavioral and Dilemma-Focused Therapy, Cognitive Behavioral Therapy for Depression
- Where
- 4 sites in Spain
- Volunteers
- 128 people
- Sponsor
- University of Barcelona
Depression, Major Depressive Disorder
eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk
This pilot randomized controlled trial seeks: (1) to determine the preliminary efficacy of our modernized collaborative care intervention for depression in improving the diabetes risk markers of hemoglobin A1c and insulin…
- Conditions
- Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms
- Trial name
- NCT04437485
- Testing
- Good Days Ahead (GDA), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Indiana University
Major Depressive Disorder, Dysthymia
Project to Improve Symptoms and Mood in People With Spinal Cord Injury
Depression is likely the most prevalent and disabling psychological complication associated with spinal cord injury (SCI). Yet no controlled depression treatment trials have been performed in this population.
- Conditions
- Major Depressive Disorder, Dysthymia, Spinal Cord Injuries
- Trial name
- PRISMS (NCT00592384)
- Testing
- venlafaxine XR
- Where
- 6 sites in United States
- Volunteers
- 133 people
- Sponsor
- University of Washington
Major Depressive Disorder
Safety and Tolerability of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder
The purpose of this study is to determine the long-term efficacy and safety of vortioxetine, once daily (QD), in adults with major depressive disorder.
- Trial name
- NCT00707980
- Testing
- Vortioxetine
- Where
- 92 sites in United States, Australia and 15 more
- Volunteers
- 836 people
- Sponsor
- Takeda
Dysthymic Disorder, Dysthymia
Desvenlafaxine vs. Placebo Treatment of Chronic Depression
The investigators are studying a new antidepressant medicine, desvenlafaxine, for the treatment of people with chronic depression.
- Conditions
- Dysthymic Disorder, Dysthymia, Chronic Depressive Disorder
- Trial name
- NCT01537068
- Testing
- Desvenlafaxine
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- New York State Psychiatric Institute
Depression, Major Depressive Disorder
eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed Patients
The objective of this randomized controlled trial is to evaluate whether the investigators modernized IMPACT intervention for depression (eIMPACT), delivered before the onset of cardiovascular disease (CVD), reduces the risk of…
- Conditions
- Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms
- Trial name
- NCT02458690
- Testing
- Beating the Blues (BtB), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- Indiana University
Major Depressive Disorder, Dysthymia Disorder
Oxytocin Add-on for Stable Depressed Patients
The objective of the study is to compare the efficacy of intranasal oxytocin versus intranasal placebo to improve depression symptoms in patients with Major Depressive Disorder (MDD) or Dysthymia Disorder.
- Trial name
- NCT01211756
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- David Feifel
Major Depressive Disorder, Dysthymia
A Study of L-DOPA for Depression and Slowing in Older Adults
Individuals with Late Life Depression (LLD) often have cognitive problems, particularly problems with memory, attention, and problem solving, all of which contribute to antidepressant non-response.
- Conditions
- Major Depressive Disorder, Dysthymia, Depression Not Otherwise Specified, Decreased Processing Speed
- Trial name
- NCT02744391
- Testing
- Levodopa
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- New York State Psychiatric Institute
Depression, Dysthymic Disorder
Duloxetine Treatment in Elderly With Dysthymia
Dysthymic disorder (DD) denotes chronic depression with fewer symptoms than major depressive disorder (MDD), and it affects ~ 2-4 % of adults with a similar prevalence in the elderly.
- Trial name
- NCT01852383
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York State Psychiatric Institute
Major Depressive Disorder, Dysthymia
L-DOPA vs. Placebo for Depression and Psychomotor Slowing in Older Adults
Individuals with Late Life Depression (LLD) often have cognitive problems, particularly problems with memory, attention, and problem solving, all of which contribute to antidepressant non-response.
- Conditions
- Major Depressive Disorder, Dysthymia, Depression
- Trial name
- NCT03761030
- Testing
- L-DOPA
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- New York State Psychiatric Institute
Major Depression, Dysthymia
Dichotic Listening as a Predictor of Medication Response in Depression
Depressed patients will have hearing tests and then be treated with up to three treatments (i.e., Fluoxetine, Imipramine) until remitted, to see whether test results predict specific outcomes.
- Conditions
- Major Depression, Dysthymia, Depressive Disorder Not Otherwise Specified
- Trial name
- NCT00296725
- Testing
- Fluoxetine, Imipramine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- New York State Psychiatric Institute
Persistent Depressive Disorder
Behavioral Activation (BA) for Medication-responsive Chronically Depressed Patients With Impaired Social Functioning
The investigators aimed to assess the ability of a modified version of Behavioral Activation for occupational and social improvement to produce change in: 1. social adjustment, 2. work functioning, 3. avoidance behavior and 4.
- Trial name
- NCT01783080
- Testing
- Behavioral Activation for return to work
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- New York State Psychiatric Institute
Major Depressive Disorder, Dysthymia
Safety and Efficacy Study of Citalopram and Lithium for the Treatment of Depressive Mood Disorder Symptoms
The investigators hypothesize that patients receiving citalopram in combination with lithium will have a greater reduction in depressive symptoms than patients receiving citalopram in combination with placebo.
- Conditions
- Major Depressive Disorder, Dysthymia, Depression Not Otherwise Specified, Borderline Personality Disorder
- Trial name
- NCT01189812
- Testing
- Lithium Carbonate, Citalopram
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Columbia Northwest Pharmaceuticals