Clinical trials: Dystonic Cramp
Dry Eye Syndromes, Meige Syndrome
Wumeiwan Jiawei Fang Use in Patients With Blepharospasm
To evaluate the efficacy and safety of Jing Fang Wu Mei Wan Jiawei Fang in the treatment of idiopathic blepharospasm using a clinical randomized controlled trial method.
- Conditions
- Dry Eye Syndromes, Meige Syndrome, Blepharospasm, Hyperactivity
- Trial name
- NCT05618470
- Testing
- Wumeiwan Jiawei Fang, botulinum toxin A
- Where
- China
- Volunteers
- 80 people
- Sponsor
- China Academy of Chinese Medical Sciences
Writer's Cramp
Sensorimotor Mapping in Patients With Writer's Cramp
Writer's cramp (WC) is a form of focal dystonia, a movement disorder characterized by sustained or intermittent muscle contractions causing abnormal, often repetitive movements, postures, or both.
- Trial name
- IWCToxin (NCT03085745)
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Writer's Cramp
Video-supervised Motor and Awareness Training in Writer's Cramp
Writer's cramp is the most common task-specific dystonia. It is characterized by involuntary co-contraction of antagonistic muscles during writing. This disabling condition may force patients to give up their occupation.
- Trial name
- NCT04611009
- Testing
- motor training, mindfulness exercises
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- University Hospital Schleswig-Holstein
Occupational; Cramp(s)
Study of Arm and Putter Movement in Golfers With Golfer's Cramp
The investigators will investigate golfers with visual evidence of an involuntary movement while putting before and after treatment with a low dose of propranolol.
- Trial name
- NCT02032758
- Testing
- Propranolol, Opal Device, Science and Motion PuttLab (SAM)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dystonic Disorder, Focal Dystonia
Characterization of Manual Dexterity by Finger Force Manipuladum (FFM) in Patients With Writer's Cramp and in Control Subjects
Writer's cramp is a focal dystonia characterized by abnormal movements and postures during writing. Limited finger independence during writing manifests as difficulty suppressing unwanted activations of neighbouring non…
- Conditions
- Dystonic Disorder, Focal Dystonia, Writer's Cramp
- Trial name
- FFM_CT (NCT03797638)
- Testing
- Finger Force Manipuladum (FFM)
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Writer's Cramp, Healthy Volunteers
Propensity to Develop Plasticity in the Parieto-Motor Networks in Dystonia From the Perspective of Abnormal High-Order Motor Processing
Background: People with dystonia have muscle contractions they can t control. These cause slow, repeated motions or abnormal postures. People with dystonia have abnormalities in certain parts of the brain.
- Conditions
- Writer's Cramp, Healthy Volunteers, Cervical Dystonia
- Trial name
- NCT02504905
- Testing
- TMS
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dystonic Disorders
Transcranial Magnetic Stimulation and Electrical Stimulation of Nerves to Study Focal Dystonia
This study will use transcranial magnetic stimulation (TMS) and electrical stimulation of nerves to examine how the brain controls muscle movement in focal hand dystonia (writer's cramp).
- Trial name
- NCT00050024
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Focal Dystonia
Motor Training to Treat Hand Dystonia
This study will evaluate the effect of motor training on focal hand dystonia in people with writer's cramp and will examine whether this training affects excitability of the motor cortex of the brain.
- Trial name
- NCT00021853
- Testing
- constraint-induced movement therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Primary Dystonia, Hemifacial Spasm
Movement Disorder Survey in East China
Movement disorder involve recurring or constant muscle contractions causing squeezing or twisting movement, such as hemifacial spasm, blepharospasm, cervical dystonias etc.
- Trial name
- MDS (NCT01168388)
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- Sir Run Run Shaw Hospital
Focal Hand Dystonia
Long-Term Motor Learning in Focal Hand Dystonia
This study will examine the effects of long-term practice of repeated finger movements in people with focal hand dystonia, as compared with healthy volunteers.
- Trial name
- NCT00325091
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Blepharospasm, Dystonia
Mexiletine for the Treatment of Focal Dystonia
Dystonia refers to a condition characterized by involuntary muscle contractions that may cause pain, abnormal posture, or abnormal movements.
- Conditions
- Blepharospasm, Dystonia, Spasm
- Trial name
- NCT00001784
- Testing
- Mexiletine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Focal Dystonia
Neurophysiology of Task-Specificity of Focal Hand Dystonia
This study will examine how the brain coordinates movement in patients with focal hand dystonia. Patients with dystonia have muscle spasms that cause uncontrolled twisting and repetitive movement or abnormal postures.
- Trial name
- NCT00309010
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Focal Dystonia
Amlodipine Plus Botulinum Toxin for Focal Dystonia
Objective: To determine if the calcium channel blockers, amlodipine can augment the effect of botulinum toxin injections in the treatment of focal dystonia.
- Trial name
- NCT00015457
- Testing
- Amlodipine plus Botulinum toxin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dystonic Disorders
Finger Individuation Training With a Training Device Versus Conventional Rehabilitation for Writer's Cramp
Writer's cramp (WC) is a focal dystonia characterized by abnormal movements and postures during writing. Limited finger independence during writing manifests as difficulty suppressing unwanted activations of neighbouring non…
- Trial name
- FIDEX (NCT02882334)
- Testing
- Finger Force Manipulandum, Conventional physiotherapy
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Dystonia
Validating a New Writer s Cramp Scale
Background: People with writer s cramp develop tightness in arm muscles and abnormal hand posture when writing, which makes writing difficult or impossible.
- Trial name
- NCT01579266
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Focal Dystonia
Survey of Sensory and Motor Tricks in Focal Dystonia
This study will collect information on (tricks) patients with focal dystonia use to relieve their symptoms. Dystonia is a movement disorder caused by sustained muscle contractions often causing twisting and abnormal posturing.
- Trial name
- NCT00054652
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dystonia, Focal, Task-specific
Repetitive Transcranial Magnetic Stimulation for the Treatment of Focal Hand Dystonia
This study investigated the short term effects of repeated administrations of repetitive-transcranial magnetic stimulation (rTMS) on clinical changes and investigate neurophysiologic responses to rTMS of the activated motor…
- Trial name
- NCT01884064
- Testing
- rTMS
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Minnesota
Writer's Cramp, Dystonias
VTS Sensorimotor Neuromodulation in WC
Writer's cramps (WC) is a focal task-specific upper limb dystonia that significantly impairs handwriting and other manual skills, affecting functionality.
- Trial name
- VTS in WC (NCT07894198)
- Testing
- Vibro-tactile stimulation
- Volunteers
- 10 people
- Sponsor
- Ottawa Hospital Research Institute
Focal Dystonia
fMRI Studies of Task Specificity in Focal Hand Dystonia
This study will examine how the brain makes involuntary spasms and contractions in patients with focal hand dystonia (FHD). Patients with dystonia have muscle spasms that cause uncontrolled twisting and repetitive movement or…
- Trial name
- NCT00310414
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Focal Hand Dystonia
Muscle Contraction in Patients With Focal Hand Dystonia
This study will examine and compare brain activity in people with focal hand dystonia (FHD) and healthy volunteers to obtain further knowledge about the underlying cause of FHD.
- Trial name
- NCT00376753
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)