Clinical trials: ED
Opioid Use Disorder
Standard Versus High Dose ED-Initiated Buprenorphine Induction
This study is a multisite double-blind, double-dummy, randomized clinical trial enrolling ED patients with untreated moderate to severe opioid use disorder (OUD) to compare Standard Dose Induction (SDI) and High Dose Induction…
- Trial name
- ED-ENVISION (NCT06494904)
- Testing
- Buprenorphine
- Where
- 5 sites in United States
- Volunteers
- 360 people
- Sponsor
- Yale University
Musculoskeletal Pain
Multimodal Management of Neck and Back Pain in the Emergency Department (Multi-ED)
The purpose of this study is to assess the feasibility and acceptability of psychologically-informed physical therapy (PIPT) in the ED in a pilot study of ED patients with neck or back pain.
- Trial name
- NCT05221125
- Testing
- Psychologically-Informed Physical Therapy (PIPT)
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Duke University
Radius Distal Fracture, Colles' Fracture
Ultrasound Directed Reduction of Colles Type Distal Radial Fractures in ED (UDiReCT)
This is a limited two centre randomized controlled feasibility trial towards a larger definitive trial designed to assess whether bed side ultrasound can reduce the rate of surgical fixation following emergency department…
- Trial name
- UDiReCT (NCT03868696)
- Testing
- MUA with active ultrasound
- Where
- 2 sites in United Kingdom
- Volunteers
- 48 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Carcinoma, Non-Small-Cell Lung
Role of FDG PET, Immune and Hypoxic Marker in NSCLC
This is a retrospective study that involves the revision of clinical, instrumental and pathologic data of an estimated cohort of maximum 130 patients with NSCLC treated with surgery with radical intent at our center.
- Trial name
- NCT02519062
- Testing
- No intervention
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Istituto Clinico Humanitas
Type 1 Diabetes Mellitus, Eating Disorders
iOmit: Reducing Intentional Insulin Misuse in Type 1 Diabetes
Individuals with type 1 diabetes who intentionally omit insulin to lose weight are at high risk for diabetes-related medical complications and premature death.
- Trial name
- iOmit (NCT02980627)
- Testing
- Therapy with Mobile App Enhancement
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- Duke University
Cellulitis
Comparing the Intravenous Treatment of Skin Infections in Children, Home Versus Hospital
Many children every year present to the Emergency Department (ED) at The Royal Children's Hospital (RCH) with cellulitis (skin infection). If it is mild, the children can go home with oral antibiotic treatment.
- Trial name
- CHOICE (NCT02334124)
- Testing
- Home, Ward, ceftriaxone
- Where
- Australia
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Pain
Comparison of Lidocaine-Prilocaine Combination and Vapocoolant for IV Cannulation Pain in the ED
Hypothesis: Lidocaine-Prilocaine Combination is as effective as Vapocoolant in treating IV cannulation pain in the emergency department.
- Trial name
- NCT04473820
- Testing
- Vapocoolant spray, Lidocaine-Prilocaine cream
- Where
- Iran
- Volunteers
- 77 people
- Sponsor
- Tehran University of Medical Sciences
Opioid Use Disorder
Reward-based Technology to Improve OUD Treatment
Millions of people in the US misuse opioids each year. Medication assisted treatment (MAT) for opioid use disorder (OUD) is highly efficacious, but only a fraction of OUD persons access MAT, and treatment non-adherence is common…
- Trial name
- OARSCM (NCT05180669)
- Testing
- OARSCM Software Application, MyMAT Software Application
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Q2i, LLC
Sepsis, Device Performance
PIVO Use for Blood Cultures in the Emergency Department
The investigators will implement a protocol for use of the PIVO device for blood culture collection in the emergency department.
- Conditions
- Sepsis, Device Performance, Emergency Medicine
- Trial name
- PIVO-ED (NCT07348289)
- Testing
- PIVO device, a needle-free blood draw device
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Intermountain Health Care, Inc.
Asthma in Children
Improving Asthma Referrals Following Emergency Department Evaluation
Asthma is the most common chronic condition among children and many children seek emergency department (ED) care. A key aspect of ED asthma management at the time of discharge is appropriate outpatient referral.
- Trial name
- NCT05072808
- Testing
- View PACCI-ED and referral recommendations
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Wayne State University
Eating Disorders, Oral Health
Oral Indicators for ED Screening
The main objective of this research project is to explore the capability of a standardized, evidence-based study tool (the OHEDs Checklist) in the early identification of oro-dental manifestations potentially indicative of an…
- Conditions
- Eating Disorders, Oral Health, Eating Disorders Symptoms
- Trial name
- OHEDS (NCT07295197)
- Where
- Italy
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Pain
Vital Capacity in Ultrasound Guided Serratus Plane Block in ED Patients With Multiple Rib Fractures
I. Background: Patients with multiple rib fractures are challenging from both pulmonary and analgesia perspectives. Adequate pain management is essential in prevention of complications secondary to decreased inspiratory volume.
- Trial name
- NCT04530149
- Testing
- Acetaminophen, Bupivacain, Saline
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Antonios Likourezos
Erectile Dysfunction
Clinical Investigation Using MED3000 Gel or Tadalafil Tablets in the Treatment of Erectile Dysfunction
An open-label investigation using MED3000 gel or tadalafil (5 mg) tablets in the treatment of erectile dysfunction in patients from 22 to 70 years of age. Each patients will be expected to participate for up to 30 weeks.
- Trial name
- NCT04984993
- Testing
- MED3000 (Male), Tadalafil 5mg (Male), MED3000 (Female)
- Where
- 18 sites in United States, Bulgaria and 2 more
- Volunteers
- 116 people
- Sponsor
- Futura Medical Developments Ltd.
Dizziness
Is The Sudden Onset of Dizziness A Symptom of Acute Liver Dysfunction?
Dizziness is one of the most common complaints among patients admitted to the emergency department (ED). In most cases, the etiology remains unclear. Dizziness has a broad differential diagnosis.
- Trial name
- NCT02733549
- Testing
- LFTs
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Adiyaman University Research Hospital
Shared Decision-making, Kidney Stone
Shared Decision-Making for the Promotion of Patient-Centered Imaging in the ED: Suspected Kidney Stones
Although a CT scan is required for some Emergency Department patients with signs and symptoms of a kidney stone, recent evidence has shown that routine scanning is unnecessary and may expose young patients to significant…
- Conditions
- Shared Decision-making, Kidney Stone, Emergencies, Radiation Exposure
- Trial name
- ED-KSS (NCT04234035)
- Testing
- Decision Aid, Standardized Educational Material (informational pamphlet)
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Baystate Medical Center
Frailty in Aging, Emergency Department Visit
Patient Experience of CFS-assessment in the ED
An increasingly common subject of interest among emergency care research is frailty, which is commonly described as a decline in several inter-related physiological systems, in addition to an increased vulnerability to stressors.
- Conditions
- Frailty in Aging, Emergency Department Visit, Patient Experience, Qualitative Research
- Trial name
- NCT06621290
- Testing
- Semi-structured interviews
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- University Hospital, Linkoeping
Abscess
Pain Management in ED for Incision and Drainage of Abscess
Patients presenting with painful procedures in the Emergency Department (ED) have been shown to frequently have inadequate pain management.
- Trial name
- NCT01881997
- Testing
- Fentanyl, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Resuscitation
Resuscitation Decisions in the Emergency Department (ED)
The investigators will retrospectively examine the connection between resuscitation decisions of admitted patients at the ED of the University Hospital of Basel and several demographic and health related measures.
- Trial name
- REDEED (NCT02575573)
- Testing
- Factors influencing resuscitation decisions of patients, Factors leading to not asking patients about resuscitation preference
- Where
- Switzerland
- Volunteers
- 10,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Type 2 Diabetes Mellitus (T2DM), Endothelial Dysfunction
Diabetes & Vardenafil
Given the protective effect of nitric oxide (NO) on the endothelium and the results obtained so far in short-term, continuous treatment with phosphodiesterase-5 (PDE5) inhibitors on parameters of endothelial function, we…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Endothelial Dysfunction, Erectile Dysfunction
- Trial name
- DiVa (NCT02219646)
- Testing
- Vardenafil
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Azienda USL Modena
Psychomotor Agitation, Behavioral Disorder
Clinical Trial of Peer Support in the ED (PCORI)
The purpose of this study is to conduct a clinical trial that tests the acceptability, fidelity, and feasibility of a peer support modified intervention for agitation management within the emergency department.
- Trial name
- NCT06556069
- Testing
- Peer-Support Enhanced Agitation Code Team (PACT)
- Where
- United States
- Volunteers
- 57,870 people, healthy volunteers welcome
- Sponsor
- Yale University