Clinical trials: ED
Apneic Oxygenation, Endotracheal Intubation
Apneic Oxygenation Including Precipitous Intubations During RSI in the ED
This RCT is testing the efficacy of apneic oxygenation during endotracheal intubation in the emergency department. Currently the standard practice in the ED when performing endotracheal intubation is that some providers use…
- Trial name
- RAPID (NCT03694379)
- Testing
- Apneic oxygenation during endotracheal intubation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rutgers, The State University of New Jersey
Diet, Healthy
mHealth to Improve Diet Quality Among Early Adolescents in SNAP-Ed in Hawaii
The goal of this 8-week clinical trial is to learn whether the PortionSize Ed mobile app helps to improve healthy eating habits among early adolescents in the Hawai'i-Food and Lifeskills for Youth (HI-FLY) program.
- Trial name
- NCT06360367
- Testing
- HI-FLY Curriculum, HI-FLY Curriculum + PortionSize Ed app
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Cocaine Use, Cocaine Intoxication
Comparing Efficacy & Safety Of TNX-1300 To Placebo With UC For Treatment Of Acute Cocaine Intoxication In ED Subjects (CATALYST)
This is a Phase 2 single-blind, randomized, multicenter study to compare the efficacy and safety of a single dose of TNX-1300 to placebo with usual care in patients with acute cocaine intoxication within the emergency department…
- Conditions
- Cocaine Use, Cocaine Intoxication, Cocaine Toxicity, Cocaine Abuse
- Trial name
- CATALYST (NCT06045793)
- Testing
- TNX-1300 (Injection)
- Where
- 6 sites in United States
- Volunteers
- 3 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Acute Pain
IV Acetaminophen as an Analgesic Adjunct
To determine the efficacy of intravenous (IV) acetaminophen as an analgesic adjunct to IV hydromorphone in the treatment of acute severe pain in the elderly Emergency Department (ED) patients.
- Trial name
- NCT02621619
- Testing
- IV acetaminophen + 0.5 mg IV hydromorphone, Normal saline + 0.5 mg IV hydromorphone
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Montefiore Medical Center
Chest Pain
Acute Chest Pain Treatment and Evaluation (ACTION) Study
Objective 1. To compare the incidence of adverse cardiac events among the patients discharged after evaluation through ACTION protocol with those through conventional protocol.
- Trial name
- NCT00434564
- Testing
- Stress nuclear scan
- Where
- Singapore
- Volunteers
- 1,690 people
- Sponsor
- Singapore General Hospital
Suicide
Emergency Department Safety Assessment and Follow-up Evaluation (ED-SAFE)
The NIMH s RFA-Suicide Prevention in Emergency Medicine Departments recognizes the emergency department (ED) as an important setting to increase suicide detection and prevention efforts but observes that evidence-based practice…
- Trial name
- ED-SAFE (NCT01150994)
- Testing
- Safety Assessment and Follow-up Telephone Intervention (SAFTI).
- Where
- 8 sites in United States
- Volunteers
- 1,440 people
- Sponsor
- University of Massachusetts, Worcester
Stress Physiology, Stress Reaction
The Human Stress Response in a Simulated ED Setting
Stress is important for health. As emergency departments (EDs) are often stressful places, a better understanding of the human stress response is important for understanding how and why patients respond as they do when they come…
- Conditions
- Stress Physiology, Stress Reaction, Substance Use Disorders, Methamphetamine-dependence
- Trial name
- NCT04317482
- Testing
- Standard social stress task, Stressful experience in the ED
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Pain, Acute
Adult Oral Ibuprofen Study for ED Pain Patients
Ibuprofen is one of the most widely used non-steroidal anti-inflammatory drug (NSAID) for management of mild -to moderate pain in the ED (acute musculo-skeletal pain, headache, dental pain).
- Trial name
- NCT03441269
- Testing
- Oral Ibuprofen
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Antonios Likourezos
Status Asthmaticus
Pleth Variability and Asthma Severity in Children
Research has shown that pleth variability can be used to assess asthma severity in children with status asthmaticus. The investigators would like to use an FDA-cleared monitor (Masimo Radical 7) which measures Pleth Variability…
- Trial name
- NCT02302261
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Northwell Health
Pain
Art Therapy Pain Management Adolescents Pediatric ED
This project is studying adolescents between the ages of 12 to 18 years that come to the emergency department and are in pain. We want to find out how well art therapy is able to decrease the pain they are experiencing.
- Trial name
- NCT03755687
- Testing
- Art Therapy Intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Columbia University
Femoral Neck Fractures, Intertrochanteric Fractures
PENG vs FICB for Hip Fracture in ED Patients
Regional anesthesia for hip fractures has been shown to decrease rates of delirium in elderly patients with hip fractures as well as improve pain compared to systemic opioids.
- Trial name
- NCT05505604
- Testing
- PENG, FICB
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
Advanced Hepatocellular Carcinoma
To Explore the Diversity of Intestinal Flora in Patients With Advanced HCC Combin ed With Anti-PD-1 and Targeted Drug Therapy and the Correlation Between Metabolites and Therapeutic Effect
The study is to explore the correlation between intestinal flora diversity and meta bolites in patients with advanced lver cancer rceiving Anti-PD-1 combined target-ed drug therapy,so that to get the analysis of intestinal flora…
- Trial name
- NCT04101747
- Volunteers
- 30 people
- Sponsor
- Sun Yat-sen University
High Fall Risk
ALERT-ED: Awareness and Linkage to Resources for At-Risk Emergency Department Patients
Falls are the leading reason for injury-related emergency department (ED) visits in older adults with high rates of ED revisits for falls.
- Trial name
- ALERT-ED (NCT07028463)
- Testing
- ALERT-ED
- Where
- United States
- Volunteers
- 20,700 people
- Sponsor
- University of Colorado, Denver
Eating Disorders
Impact of a Mobile App-Based Waitlist Intervention on Readiness for Eating Disorder Treatment
The goal of this randomized controlled trial is to evaluate whether a mobile app-based motivational interviewing intervention (MI-Coach: ED) can improve motivation and readiness for treatment in adults with eating disorders who…
- Trial name
- MI-Coach: ED (NCT06801197)
- Testing
- MI-Coach: ED Mobile App
- Where
- 3 sites in Canada
- Volunteers
- 74 people
- Sponsor
- University of British Columbia
Alcohol Abuse, Episodic Drinking Behavior
AURAIA Study : Impact Evaluation at 3 Months Follow-up of a Brief Motivational Intervention in Reducing Alcohol Consumption Among Adolescents Aged 16-24 in Pontchaillou Hospital Emergency Department in Rennes, France
The purpose of this study is to evaluate the effectiveness of a Brief Motivational Intervention (BMI), in reducing alcohol consumption among patients with hazardous or harmful drinking admitted in emergency department (ED).
- Trial name
- AURAIA (NCT01435668)
- Testing
- Brief Motivational Intervention (BMI), Simple written advice
- Where
- France
- Volunteers
- 258 people
- Sponsor
- Rennes University Hospital
Non-specific Complaints
Biomarker-enhanced ED Disposition Decisions
Patients presenting to emergency departments (ED) with non-specific complaints (NSC) such as "not feeling well", "feeling weak", "being tired", "general deterioration" are a very common and well-known, but poorly studied patient…
- Trial name
- BANC4 (NCT00920491)
- Testing
- biomarker-enhanced disposition decision with proADM
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Basel, Switzerland
Alcoholic Intoxication
Emergency Department (ED) Triage of Alcohol Abuse
Retrospective study of adult patients (> 16 y) admitted to Geneva University Hospitals with alcohol abuse. Triage criteria will be reviewed. Patients characteristics and patient flow in the ED will be described.
- Trial name
- NCT02449772
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 775 people
- Sponsor
- University Hospital, Geneva
Social Determinants of Health
Social Needs Screenings in ED
This study will determine whether existing Health Information Technology can be leveraged to 1) implement a universal, patient-centered social needs assessment and referral process during routine Emergency Department care; 2)…
- Trial name
- NCT04630041
- Testing
- 211 Referral
- Where
- United States
- Volunteers
- 5,081 people
- Sponsor
- Andrea Wallace
Post Traumatic Pain
Efficacy Study of Nebulized Morphine and Intravenous Morphine in Post Traumatic Pain
In the emergency department, 60% of patients have an acute pain. Appropriate management of acute pain is a public health priority according to who recommendations.
- Trial name
- NCT01123551
- Testing
- nebulized morphine, Intravenous morphine
- Where
- Tunisia
- Volunteers
- 200 people
- Sponsor
- University of Monastir
Migraine, Pain
Nitrous Oxide for Acute Migraine Pain in the Emergency Room (ED)
BACKGROUND Migraine headaches account for 8-18% of all headaches seen in pediatric emergency rooms. Standard treatment includes IV pain medications, anti-emetics, and IV fluids.
- Trial name
- NCT01287052
- Testing
- Nitrous Oxide
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota