Clinical trials: ED
Heart Failure, Heart Failure Acute
B-lines Lung Ultrasound Guided ED Management of Acute Heart Failure Pilot Trial
Nearly 80% of acute heart failure (AHF) patients admitted to the hospital are initially treated in the emergency department (ED). Once admitted, within 30 days post-discharge, 27% of patients are re-hospitalized or die.
- Conditions
- Heart Failure, Heart Failure Acute, Acute Cardiac Pulmonary Edema, Acute Cardiac Failure
- Trial name
- BLUSHED-AHF (NCT03136198)
- Testing
- LUS-guided strategy-of-care, Usual Care, Intravenous Loop Diuretic
- Where
- 6 sites in United States
- Volunteers
- 130 people
- Sponsor
- Indiana University
Hypotension, Point of Care Ultrasound
Sonography in Hypotension and Cardiac Arrest in the Emergency Department.
This study is designed to determine if there is any relationship between performing an abdominal ultrasound on patients who present with hypotension and their clinical outcomes (as measured by 7, 30 day and discharge mortality).
- Conditions
- Hypotension, Point of Care Ultrasound, Shock
- Trial name
- SHoC-ED (NCT01419106)
- Testing
- Ultrasound (A point of care ultrasound protocol)
- Where
- 6 sites in Canada, South Africa
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Horizon Health Network
Migraine
Headache in the Emergency Department (ED) - A Multi-Center Research Network to Optimize the ED Treatment of Migraines
Migraines are a specific type of headache that frequently recur and are very painful. Although there are many medications that are effective against migraines, none of these medications cure 100% of migraines.
- Trial name
- NCT00122278
- Testing
- Dexamethasone
- Where
- 3 sites in United States
- Volunteers
- 205 people
- Sponsor
- Montefiore Medical Center
Suicide
Emergency Department Safety Assessment and Follow-up Evaluation 2
Many patients at risk for suicide are discharged from the ED with little or no intervention. Evidence-based suicide prevention interventions, like universal screening and safety planning should be adopted in clinical practice to…
- Trial name
- ED-SAFE-2 (NCT02453243)
- Testing
- Safety Planning, A Lean Implementation Strategy
- Where
- 8 sites in United States
- Volunteers
- 14,250 people
- Sponsor
- University of Massachusetts, Worcester
Small Bowel Obstruction, Point of Care Ultrasound
POCUS for Small Bowel Obstruction in the ED: a Retrospective Study
This study protocol aims to evaluate the impact of point-of-care ultrasound (POCUS) on the diagnosis and management of small bowel obstruction (SBO) in the emergency department (ED).
- Trial name
- SBOCUS (NCT05864378)
- Volunteers
- 230 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Suicide
STAT-ED: Suicidal Teens Accessing Treatment After an Emergency Department Visit
This study looks to implement a novel intervention (STAT-ED) for children who screen positive to suicide ideation. The intervention looks to collect data from several different measures and then randomize participants into one of…
- Trial name
- STAT-ED (NCT01779414)
- Testing
- STAT-ED Intervention
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Erectile Dysfunction and Coronary Artery Disease
Assessment of Erectile Dysfunction and Coronary Artery Disease Severity
This study provides a comprehensive bidirectional assessment to determine the prevalence, clinical severity, and anatomical correlation between erectile dysfunction and coronary artery disease severity in patients presenting to…
- Trial name
- BA-EDCAD (NCT07813195)
- Testing
- Selective Coronary Angiography
- Volunteers
- 120 people
- Sponsor
- Assiut University
Musculoskeletal Pain
Comparing Five Oral Analgesics for Treatment of Acute Pain in the Emergency Department (ED)
This study compares the efficacy of five oral analgesics: 5 mg oxycodone + 325 mg acetaminophen, 5 mg hydrocodone + 300 mg acetaminophen, 30 mg codeine + 300 mg acetaminophen, 400 mg ibuprofen + 1000 mg acetaminophen, and 800 mg…
- Trial name
- NCT03173456
- Testing
- oxycodone/APAP, hydrocodone/APAP, codeine/APAP
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Albert Einstein College of Medicine
Goals
Shared Decision Making to Improve Goals of Care in the ED
This project will develop and refine a shared decision making (SDM) intervention (decision aid tool) to improve and normalize high quality end of life discussions in the Emergency Department (ED) setting.
- Trial name
- NCT03833622
- Testing
- Shared Decision Aid Assessment
- Where
- 3 sites in United States
- Volunteers
- 230 people
- Sponsor
- Mayo Clinic
Acute Pain
Acetaminophen Versus IV Hydromorphone for Pain in the Elderly in the ED
Intravenous opioids are the mainstay of acute, severe pain treatment in Emergency Departments (ED) across the country. Acetaminophen, given orally, has also been used for treatment of mild to moderate pain.
- Trial name
- NCT03521102
- Testing
- Acetaminophen 1000mg IV, Hydromorphone 0.5 mg IV
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Montefiore Medical Center
Acute Pain, Opioid Use
Low-dose KETamine as an Adjunct to MOrphine for Acute Pain in the ED
The KetMo study is an investigator-initiated, randomized, parallel group, double blinded trial investigating if ketamine as an adjunct to morphine improves pain treatment in the ED.
- Trial name
- KetMo (NCT05422001)
- Testing
- low dose ketamine
- Where
- Denmark
- Volunteers
- 116 people
- Sponsor
- University of Aarhus
Organic Erectile Dysfunction
Assessment of Penile Vibratory Stimulation Using the Viberect in Men With Mild-Moderate ED
The primary objective of this study is to assess the safety, acceptability, and satisfaction of penile vibratory stimulation in treatment of erectile dysfunction (ED).
- Trial name
- NCT01715571
- Testing
- Viberect
- Where
- 2 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Shock, Dyspnea
AFrican Resuscitation Ultrasound In Critically-ill Adults
The proposed study is a prospective cohort study in which a select group of emergency physicians at Komfo Anokye Teaching Hospital (KATH) in Ghana will be trained in cardiopulmonary ultrasound (CPUS).
- Trial name
- AFRICA (NCT02794909)
- Testing
- Cardiopulmonary ultrasound exam
- Where
- Ghana
- Volunteers
- 180 people
- Sponsor
- Rockefeller Oteng
Abscess
US Guided Versus BlindI&D for Treatment of Soft Tissue Abscesses in the ED
Standard treatment for a soft tissue abscess involves incision over the area of maximum fluctuance with drainage of purulence from the abscess cavity.
- Trial name
- NCT02264392
- Testing
- Ultrasound Guided Incision and Drainage, Blind Incision and Drainage
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Massachusetts, Worcester
Small Cell Lung Cancer
Etoposide-Carboplatin Alone or With Endostar for Extensive Disease Small Cell Lung Cancer (ED-SCLC)
Background: The effect of existing treatment modalities of extensive disease small-cell lung cancer (ED-SCLC) is unsatisfactory. Progress of new strategies including more efficient therapy is wanted.
- Trial name
- NCT00912392
- Testing
- Endostar, Etoposide-Carboplatin
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Shandong Simcere-Medgenn Bio-pharmaceutical Co., Ltd
Dental Pain
Dental Block for Pain Relief in ED Dental Pain Patients
This will be a prospective, observational cohort study assessing immediate pain relief from dental block in ED patients presenting with dental pain. The study will be conducted in the Community Regional Medical Center ED.
- Trial name
- NCT05351099
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- University of California, San Francisco
Sickle Cell Disease, Vaso-occlusive Crisis
Comparison of Patient Controlled Analgesia (PCA) Versus Bolus Narcotic Therapy for the Treatment of Vaso-Occlusive Crisis (VOC)
This research is being done to find out the best way to give narcotics for pain relief in adults with sickle cell disease and painful crisis. This study is a comparison of two ways of giving narcotics.
- Trial name
- NCT00711698
- Testing
- Patient controlled analgesia, nurse-administered intermittent IV bolus opioid therapy (NAIBOD)
- Where
- United States
- Sponsor
- Johns Hopkins University
Stroke, Ischemic
Validation of TriAGE+ for Predicting Stroke Risk in ED Patients Presenting With Dizziness
Ischemic cerebrovascular diseases originating from the brain's posterior circulation account for 20-25% of cases. Among patients diagnosed with cerebellar infarction, 10% present with isolated dizziness as their sole symptom.
- Trial name
- NCT06641050
- Testing
- TRIAGE+ score assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 818 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Ileus; Mechanical, Contrast-induced Nephropathy
Investigation of Relationship Between Contrast Nephropathy and Caval Index Measurement in Patients With Ileus in ED
In this study, the investigators aimed to evaluate the incidence of vena cava inferior diamater on ultrasound guidance of intravascular volume before diagnosis of contrast enhanced CT for diagnostic purposes in ileus patients and…
- Trial name
- NCT03261518
- Testing
- inferior vena cava ultrasound
- Volunteers
- 250 people
- Sponsor
- Derince Training and Research Hospital
Erectile Dysfunction (ED)
Sano V First In Human Study to Treat ED
A Prospective, First in Human Study to Evaluate the Safety and Performance of a Flow Modification System
- Trial name
- FMS (NCT03651024)
- Testing
- ED surgery
- Volunteers
- 10 people
- Sponsor
- Sano V Pte Ltd