Clinical trials: ED
Pain
Nasal Ketamine for Minor Procedures in Children
Nasal Ketamine has previously been tested in children for deep sedation or preoperative anxiolysis. The investigators intend to test the efficacy of low dose nasal Ketamine in children undergoing minor procedures in the emergency…
- Trial name
- NCT02839928
- Testing
- Intranasal ketamine, Intranasal atomizer, EMLA
- Volunteers
- 20 people
- Sponsor
- Kaplan Medical Center
Dehydration, Acute Gastroenteritis
Comparing Speedlyte and IV Rehydration Treating Children With Gastroenteritis in a Pediatric Emergency Department (ED)
To compare length of stay (LOS) of pediatric patients in a pediatric emergency room presenting with Gastroenteritis treated with IV rehydration versus oral Speedlyte rehydration.
- Trial name
- NCT03562702
- Testing
- Standard IV Rehydration Therapy, Oral Rehydration Therapy (ORT)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Nutrient Intake Inadequacy
The Indiana SNAP-Ed Long-term Study Sequel
The goal of the study is to determine the immediate and long-term effects of SNAP-Ed on the dietary intake of participants.
- Trial name
- NCT03436784
- Testing
- Indiana SNAP-Ed
- Where
- United States
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- Purdue University
Music Therapy, Patient Satisfaction
Music in the Emergency Department (ED): Phase II
The investigators will conduct a prospective quasi-experimental design study of patients in the University of Florida Health Emergency Department.
- Trial name
- MUES (NCT02363179)
- Testing
- Live preferential music
- Where
- United States
- Volunteers
- 1,107 people, healthy volunteers welcome
- Sponsor
- University of Florida
Erectile Dysfunction
Evaluate the Safety and Feasibility of Injecting PMD-MSC Into the Penis to Treat the Symptoms of Mild to Moderate ED
Prospective, open-label, non-randomized, study to be conducted at a single center. Ten subjects will undergo an injection of Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs) into the penis for the treatment of mild to…
- Trial name
- PMD-MSC-ED-01 (NCT02398370)
- Testing
- Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Melissa Marchand
Erectile Dysfunction (ED), Erectile Dysfunctions
A Single-Arm, Dose Escalation of an Intraurethral Alprostadil Paste for Erectile Dysfunction
This is a single arm dose escalation trial of a mucoadhesive intraurethral polymer suspension of alprostadil (ST-04) and will investigate the efficacy of 3 dose levels of ST-04 in adult males with a clinical diagnosis of Erectile…
- Conditions
- Erectile Dysfunction (ED), Erectile Dysfunctions, Erectile Function
- Trial name
- NCT07601646
- Testing
- ST-04
- Where
- Canada
- Volunteers
- 83 people
- Sponsor
- Ryan Flannigan, MD
Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
Regenerative Injection of Stem Cells or Stem Cell-derived Exosomes for Erectile Dysfunction (RISE)
The goal of this prospective observational study is to evaluate whether injections of stem cells derived from the patient's own fat tissue (adipose tissue) can improve erectile function in men aged 30 to 75 who have erectile…
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- RISE (NCT06605508)
- Testing
- Autologous Adipose Tissue-Derived Stem Cell Injection for Erectile Dysfunction, Stem cell-derived Exosomes Injection for Erectile Dysfunction
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Jumeirah American Clinic
Erectile Dysfunction
Long-Term Safety and Efficacy Study of Avanafil in Men With Erectile Dysfunction
This open-label study is being conducted to evaluate the long-term safety, tolerability, and efficacy of avanafil in men with mild to severe erectile dysfunction.
- Trial name
- NCT00853606
- Testing
- avanafil
- Where
- 40 sites in United States
- Volunteers
- 712 people
- Sponsor
- VIVUS LLC
Primary Headache
Dexamethasone Plus Metoclopramide Versus Paracetamol/NSAIDs for Primary Headache
Primary headache disorders are among the most common neurological conditions presenting to emergency departments and can significantly impair quality of life and daily functioning.
- Trial name
- DMPH (NCT07605065)
- Testing
- Dexamethasone Plus Metoclopramide, Paracetamol/NSAIDs
- Volunteers
- 94 people
- Sponsor
- Pak Emirates Military Hospital
Adverse Effect
Different Crystalloid Coload Volumes on the 90% ED of Norepinephrine
The purpose of this study is to investigate the effect of different crystalloid coload volumes on the 90% effective dose of prophylactic norepinephrine infusions for preventing postspinal anesthesia hypotension during cesarean…
- Trial name
- NCT05690334
- Testing
- Crystalloid - 0 ml/kg, Crystalloid - 5 ml/kg, Crystalloid - 10 ml/kg
- Where
- China
- Volunteers
- 90 people
- Sponsor
- General Hospital of Ningxia Medical University
Erectile Dysfunction
ANDRO 2002: Dehydroepiandrosterone (DHEA) or Testosterone Versus Placebo in Men With Sexual Dysfunction
Androgen deficiency in the aging male is poorly understood. The objective of this study will be to determine the role of testosterone and DHEA in enhancing sexual interest and sexual performance.
- Trial name
- NCT00202163
- Testing
- DHEA, Testosterone
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Queen's University
Dementia, Caregiver
ED PLWD/Care Partner Text Messaging
The purpose of this research study is to develop and test a text-messaging intervention for emergency department (ED) discharge care transitions experienced by caregivers of older adults with cognitive impairment.
- Conditions
- Dementia, Caregiver, Emergency Department, Mobile Health Technology (mHealth)
- Trial name
- CAPTURE (NCT07423871)
- Testing
- CAPTURE Text Message Care Transition Support
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Acute Chest Pain, NSTEMI - Non-ST Segment Elevation MI
Emergency Department Triage of Patients With Acute Chest Pain Based on the ESC 0/1-hour Algorithm (PRESC1SE-MI)
The PRESC1SE-MI study compares two algorithms for triage of patients presenting with chest pain and symptoms of heart attack (myocardial infarction) to the emergency department.
- Trial name
- PRESC1SE-MI (NCT05649384)
- Testing
- European Society of Cardiology hs-cTnT/I 0 h/1 h algorithm, European Society of Cardiology hs-cTnT/I 0 h/3 h algorithm
- Where
- 20 sites in United States, Australia and 9 more
- Volunteers
- 64,374 people
- Sponsor
- University Hospital, Basel, Switzerland
ED Patients With Chronic Medical Illnesses
An Emergency Department-To-Home Intervention to Improve Quality of Life and Reduce Hospital Use
The purpose of this study is to determine if assigning older, chronically ill patients a healthcare coach after they leave the Emergency Department (ED) improves their quality of life and reduces the need for hospital-based care.
- Trial name
- NCT02079987
- Testing
- ED-to-home care transition intervention, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 1,101 people
- Sponsor
- University of Florida
Contraception, Contraception Behavior
Contraception Initiation Feasibility in the Pediatric ED
Many female adolescents using the pediatric emergency department (ED) are at higher risk for unintended pregnancy. This is a significant public health issue and hormonal contraception is the mainstay of prevention.
- Trial name
- NCT03559634
- Testing
- Intervention Group, Control Group
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Sepsis, Infections
TriVerity™ for Improved Management of Emergency Department (ED) Patients With Suspected Infections
A pre/post interventional use trial, with ED patients who are initially triaged to locations other than a dedicated patient room in the main ED (e.g., waiting room, hallway bed, and/or the staging area/fast track area) with…
- Conditions
- Sepsis, Infections, Tachycardia, Fever
- Trial name
- TIMED (NCT06637904)
- Testing
- TriVerity Test
- Where
- 2 sites in United States
- Volunteers
- 320 people
- Sponsor
- Inflammatix
Radiographic Contrast Agent Nephropathy, Pulmonary Embolism
NAC, NaHCO3 and NS Prophylaxis for CTPA in the ED on Suspicion of PE: A Randomized Controlled Trial
Study objective: The purpose of this study was to compare the role of the prophylactic protocols N-acetylcysteine (NAC) plus normal saline, sodium bicarbonate (NaHCO3) plus normal saline and intravenous normal saline (NS) alone…
- Trial name
- NCT02483143
- Testing
- NAC, NaHCO3, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 231 people
- Sponsor
- Karadeniz Technical University
Asthma
Trial of One Versus Two Doses of Dexamethasone for Pediatric Asthma Exacerbation
Comparing one versus two doses of oral dexamethasone for the treatment of asthma in the pediatric emergency department.
- Trial name
- R2D2 (NCT02725008)
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Geoffrey W Jara-Almonte
Erectile Dysfunction
Clinical Trial Studying the Efficacy and Safety of IP2018 in Depressed, Erectile Dysfunction (ED) Patients
This is a Phase IIa, randomised, double-blind, placebo-controlled, 3-period, crossover study to assess two single oral dose levels of IP2018. It is planned to enrol 24 patients.
- Trial name
- NCT04686916
- Testing
- IP2018
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Initiator Pharma
Body Image, Physical Activity
SDT-Based Intervention for Exercise Motivation in Female Students
Physical inactivity, maladaptive exercise motives, and body image concerns are highly prevalent among young adult women and are associated with reduced psychological well-being and increased risk for disordered eating.
- Trial name
- No acronym use (NCT07506343)
- Testing
- Experimental group will receive a face-to-face psychoeducational program grounded in Self-Determination Theory. Control group will no receive any psychoeducational program
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria