Clinical trials: ED
Erectile Dysfunction, Hypogonadism
Co-Administering Testosterone With PDE5 Inhibitors in ED Patients Non Responders to PDE5 Inhibitors Alone
30 to 50% of the patients presenting with Erectile Dysfunction (ED) do not respond to PDE V Inhibitor therapy, which is presently considered as the first choice treatment for most ED patients.
- Trial name
- NCT00244023
- Testing
- Testosterone gel, testosterone
- Where
- France
- Volunteers
- 173 people
- Sponsor
- SELARL du Dr Jacques BUVAT
Streptococcal Pharyngitis
Rapid POC GAS Diagnostics in the Paediatric ED
Randomized trial evaluating effectiveness of rapid point-of-care molecular GAS diagnostics as compared to standard culture-based techniques for the management of children aged 3-18 years of age presenting with sore throat to…
- Trial name
- NCT04247243
- Testing
- Rapid testing, Reference testing
- Where
- Canada
- Volunteers
- 392 people
- Sponsor
- Hamilton Health Sciences Corporation
Frailty, Aged
Triage Assessment and NEWS-score as Risk Predictor in Older Frailty Adults in the ED
Emergency Department Triage Systems have not been shown to sufficiently recognize frail elderly patients in need of urgent assessment and care.
- Conditions
- Frailty, Aged, Triage
- Trial name
- NCT03783234
- Where
- Finland
- Volunteers
- 1,711 people
- Sponsor
- Helsinki University Central Hospital
Erectile Dysfunction, Localized Prostate Carcinoma
LiSWT for Nerve Sparing Radical Prostatectomy ED
This phase I clinical trial studies how well low intensity shockwave therapy (LiSWT) improves erectile function in patients who have had nerve-sparing radical prostatectomy (NS-RP), a type of surgery that attempts to save the…
- Conditions
- Erectile Dysfunction, Localized Prostate Carcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8
- Trial name
- NCT05877144
- Testing
- Nerve-Sparing Prostatectomy, Medical Device Usage and Evaluation, Duplex Ultrasound
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Thomas Jefferson University
Small Cell Lung Cancer, Extensive-stage Small Cell Lung Cancer
Ipilimumab + Nivolumab w/Thoracic Radiotherapy for Extensive-Stage Small Cell Lung Cancer
The purpose of the safety run in Phase I portion of this study is to confirm the recommended Phase II dose of ipilimumab and nivolumab among participants treated with combined thoracic radiation therapy (30 Gy in 10 fractions)…
- Trial name
- NCT03043599
- Testing
- Thoracic Radiation Therapy, Ipilimumab, Nivolumab
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Pregnant Women
Estimation of the Effective Dose (ED) 95 of Intrathecal Hyperbaric Prilocaine 2% for Scheduled Cesarean Delivery.
Prilocaine is a local anesthetic drug which as an intermediate duration of action shorter than bupivacaine 0,5% that is usually used for spinal anesthesia in scheduled cesarean section.
- Trial name
- NCT03607916
- Testing
- Hyperbaric prilocaine 2%, Morphine
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Wounds and Injuries, Lacerations
Comparison of Skinlink With Suture for ED Patients
The purpose of this study is to determine whether suture using the Device of "Leukosan Skinlink" is more faster and safer than that of "nylon" in the treatment of simple wound for ED patients.
- Trial name
- Skinlink (NCT02333877)
- Testing
- Skinlink, Nylon
- Where
- South Korea
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Hearing Loss, Emergency Service
Hearing Impairment, Strategies and Outcomes in VA Emergency Departments
HearVA involves six VA facility emergency departments (ED) over a 3-year intervention period. The first part of this study will test whether providing personal amplifiers to Veteran ED patients who self-report hearing difficulty…
- Conditions
- Hearing Loss, Emergency Service, Hospital Readmission
- Trial name
- HearVA-ED (NCT05028972)
- Testing
- Personal Amplifier, No Personal Amplifier
- Where
- 6 sites in United States
- Volunteers
- 1,050 people
- Sponsor
- VA Office of Research and Development
Vegetable Acceptance in Early Childhood, Vegetable Intake
Evaluating the Implementation and Impact of an Enhanced SNAP-Ed Delivered Curriculum in Low-income Preschools
This evaluation project aims to assess the impact of the Penn State Child Health Research Center's final year of SNAP-Ed funded nutrition education program in low-income preschool classrooms in Pennsylvania.
- Conditions
- Vegetable Acceptance in Early Childhood, Vegetable Intake, Knowledge
- Trial name
- NCT07366437
- Testing
- Rainbow Veggie Club
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Penn State University
Nausea
Comparison of Ondansetron, Metoclopramide and Promethazine for the Treatment of Nausea and Vomiting in the Adult ED
The purpose of this study is to compare the effectiveness of ondansetron, metoclopramide, and promethazine for the treatment of nausea in the adult emergency department population.
- Trial name
- NCT00655642
- Testing
- Ondansetron, Metoclopramide, Promethazine
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Vanderbilt University
Pain
Safety and Efficacy of Intravenous Hydromorphone in Elderly Emergency Department Patients With Acute Severe Pain
The hydromorphone protocol is more effective than usual care in Emergency Department (ED) patients age 65 years and older in terms of proportion who choose to forgo additional pain medication within 60 minutes post-baseline in…
- Trial name
- NCT01429285
- Testing
- Hydromorphone, Usual care
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Erectile Dysfunction
Clinical Investigation Using MED3000 Gel or Tadalafil Tablets in the Treatment of Erectile Dysfunction
An open-label investigation using MED3000 gel or tadalafil (5 mg) tablets in the treatment of erectile dysfunction in patients from 22 to 70 years of age. Each patients will be expected to participate for up to 30 weeks.
- Trial name
- NCT04984993
- Testing
- MED3000 (Male), Tadalafil 5mg (Male), MED3000 (Female)
- Where
- 18 sites in United States, Bulgaria and 2 more
- Volunteers
- 116 people
- Sponsor
- Futura Medical Developments Ltd.
Bronchiolitis
Heliox-Driven Racemic Epinephrine in Treatment of Bronchiolitis in Pediatric ED Patients
The purpose of this study is to assess whether children with moderate to severe bronchiolitis treated with standard racemic epinephrine therapy via 70:30 helium-oxygen (heliox) driven nebulization will have improvements in…
- Trial name
- NCT00116584
- Testing
- heliox, oxygen
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Emergence Delirium
Effect of Fentanyl on Emergence Delirium (ED) on Children Undergoing Adeno-tonsilectomy at Kenyatta National Hospital (KNH)
This study will be a randomized double blind placebo controlled clinical trial among children undergoing adeno-tonsillectomy in KNH.
- Trial name
- NCT02753725
- Testing
- Fentanyl, Normal saline
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Nairobi
Carbon Monoxide Poisoning
Suspected Cases of Carbon Monoxide Poisoning in the ED
The purpose of this study is to collect non-invasive observational data in suspected or known carbon monoxide poisoning.
- Trial name
- NCT03004235
- Testing
- Observational data collection
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Nonin Medical, Inc
Extensive-stage Small Cell Lung Cancer
A Study of Niraparib as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Patients With Extensive Stage Small Cell Lung Cancer
Niraparib is a PARP inhibitor. The study is a 2:1 randomized, double-blind, placebo-controlled, multi-center,phase 3 study of ZL-2306 (niraparib) as maintenance therapy following first-line platinum-based chemotherapy in patients…
- Trial name
- NCT03516084
- Testing
- ZL-2306(nirapairb)
- Where
- 33 sites in China
- Volunteers
- 185 people
- Sponsor
- Zai Lab (Shanghai) Co., Ltd.
Advanced Hepatocellular Carcinoma
To Explore the Diversity of Intestinal Flora in Patients With Advanced HCC Combin ed With Anti-PD-1 and Targeted Drug Therapy and the Correlation Between Metabolites and Therapeutic Effect
The study is to explore the correlation between intestinal flora diversity and meta bolites in patients with advanced lver cancer rceiving Anti-PD-1 combined target-ed drug therapy,so that to get the analysis of intestinal flora…
- Trial name
- NCT04101747
- Volunteers
- 30 people
- Sponsor
- Sun Yat-sen University
Pain, Acute
PENTHROX™ in the Canadian Emergency Department (ED)
This Canadian, multi-centre, prospective, real world study is designed to evaluate the effectiveness of low dose methoxyflurane (MEOF) (PENTHROX™) for the treatment of moderate to severe pain associated with trauma in the…
- Trial name
- ADVANCE-ED (NCT03868436)
- Testing
- Methoxyflurane 3mL
- Where
- 6 sites in Canada
- Volunteers
- 99 people
- Sponsor
- Purdue Pharma, Canada
Penicillin Allergy, Pediatric Emergency Medicine
Oral Challenge in the Pediatric ED
Our primary objective was to demonstrate the feasibility of utilizing a novel penicillin allergy questionnaire in the PED to identify a low-risk group of patients who will complete an oral challenge in the PED to test for an…
- Trial name
- OPEN (NCT03404804)
- Testing
- Amoxicillin
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Medical College of Wisconsin
Dyspnea
Vibration Response Imaging (VRI) in Dyspnea Patients Presenting to the ED
For the patient with acute dyspnea in the ED, early differentiation between CHF and non-CHF causes is essential for proper management.
- Trial name
- NCT01206621
- Where
- 8 sites in United States, Israel
- Volunteers
- 530 people
- Sponsor
- Deep Breeze