Clinical trials: EEG Brain Oscillations
Schizophrenia
Effects of Brain Stimulation on Cognition, Oscillations and GABA Levels in Schizophrenia
People with schizophrenia often have problems with attention, learning and memory and other cognitive abilities that interfere with their work and school performance.
- Trial name
- NCT04267003
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Experimental Pain in Healthy Human Subjects
Intra- and Inter-individual Differences of Pain
Pain is a highly subjective and variable phenomenon. Different persons perceive objectively identical nociceptive stimuli differently.
- Trial name
- NCT05616091
- Testing
- painful stimulation by using a laser device (DEKA Stimul 1340, Calenzano, Italy)
- Where
- Germany
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
EEG Brain Oscillations, Alzheimer's Disease (AD)
Effects of Endogenous Gamma Light Stimulation on Brain Oscillations in Cognitively-normal Older Adults
This study aims to evaluate the effects of endogenous gamma non-flickering light stimulation on resting-state EEG rhythms and cognitive function in cognitively healthy older adults.
- Conditions
- EEG Brain Oscillations, Alzheimer's Disease (AD), Cognitively Normal Older Adults
- Trial name
- NCT06715995
- Testing
- Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA)
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Experimental Pain in Healthy Human Participants
Sensory Evidence and Expectations in Pain Processing
Pain is a highly complex and subjective phenomenon which is not only rooted in sensory information but also shaped by cognitive processes such as expectation.
- Trial name
- NCT04296968
- Testing
- Painful stimulation using a laser device (DEKA Stimul 1340, Calenzano, Italy), Visual cueing
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Chronic Pain, Neck Pain
Examining the Effect of Lateralization Imagery Training on EEG Brain Oscillations in Individuals With Chronic Neck Pain
In this study, it was planned to investigate the effectiveness of lateralization and imagery training in individuals with chronic neck pain.
- Trial name
- NCT06679335
- Testing
- Lateralization Imagery Training
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Chronic Pain, Manipulation
Comparison of the Effect of Spine Grade I and II Manipulation and a PNE Video on Brainwaves: Pilot Study
The purpose of this study is to determine the effect of the use of a pain neuroscience educational video instruction on brainwave activity and compare this to the effects of a grade I \& II PA spinal oscillations of the spine…
- Conditions
- Chronic Pain, Manipulation, Psychologic
- Trial name
- NCT04908670
- Testing
- Understanding Pain in less than 5 minutes, and what to do about it! https://www.youtube.com/watch?v=C_3phB93rvI, PA manipulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Florida Gulf Coast University
Schizophrenia, Schizoaffective Disorder
Clonazepam Effects on Brain Oscillations and Cognition in Schizophrenia
Cognitive deficits are some of the most prominent and disabling symptoms of schizophrenia. Evidence suggests that schizophrenia involves alterations to the functioning of a neural system under the control of a brain chemical…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- KGB (NCT03061136)
- Testing
- Clonazepam
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) Amnestic
Acoustic Stimulation During Sleep: Effects on Memory and p-tau217 in MCI
The goal of this clinical trial is to determine whether acoustic stimulation during sleep can enhance slow-wave sleep (SWS), improve cognitive function, and reduce AD-related pathology in individuals with mild cognitive…
- Conditions
- Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) Amnestic, Cognitively Unimpaired
- Trial name
- PAS-MCI (NCT07529015)
- Testing
- Plase-Locked Acoustic Stimulation during slow-wave sleep
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Institut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré (IRBLleida)
Major Depression, Sleep
Sleep TMS for Depression
The goal of this study is to establish the feasibility, tolerability, and preliminary efficacy of sleep-state transcranial magnetic stimulation (TMS) for enhancing plasticity in depression treatment.
- Trial name
- NCT06824415
- Testing
- TMS
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Stanford University
Alzheimer's Disease, 40 Hz Stimulation
Effects of Combined 40 Hz Audio-visual Stimulation and Cognitive Games on Alzheimer's Disease
In addition to ongoing drug treatments for Alzheimer Disease (AD), protective approaches that can halt the progression of the disease are of particular importance.
- Conditions
- Alzheimer's Disease, 40 Hz Stimulation, EEG Brain Oscillations
- Trial name
- NCT06595511
- Testing
- Sensory Entrainment-Integrated Cognitive Game Kit
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Alzheimer Disease, Early Onset
The Resting-state EEG Gamma Oscillations in Alzheimer's Disease
The literature suggests a strong association between amyloid accumulation and gamma alterations, emerging gamma activity as a biomarker candidate for Alzheimer's pathology.
- Trial name
- EEG (NCT05989087)
- Testing
- CSF
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Görsev Yener, MD, PhD
EEG Brain Oscillations, Balance Exercises
The Effect of Balance Exercises on Cognitive Function
The aim of our study is to examine the effects of balance exercises performed in virtual and real environments on visual-spatial attention and mental rotation in healthy young adult individuals using EEG brain oscillations.
- Trial name
- NCT06151093
- Testing
- Video-based games intervention, Balance exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Stroke, Cerebrovascular Accident (CVA)
Investigating Central Contributions to Fatigue Using Non-invasive Brain Stimulation
The goal of this interventional study is to understand the contribution of the central components to the manifestation of neuromuscular fatigue in stroke survivors.
- Conditions
- Stroke, Cerebrovascular Accident (CVA), Ischemia Stroke, Hemorrhage Stroke
- Trial name
- NCT07613970
- Testing
- Transcranial alternating current stimulation (tACS)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Balance Assessment, Visuospatial/Perceptual Abilities
Relationship Between Visuospatial Attention and Balance
The term equilibrium is related to Newton's first law and, as used in mechanics, describes the state where the effect of the forces acting on an object is zero. Equilibrium is divided into two types: static and dynamic.
- Conditions
- Balance Assessment, Visuospatial/Perceptual Abilities, EEG Brain Oscillations
- Trial name
- NCT07714434
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Gedik University
Experimental Pain in Healthy Human Subjects
How do Alpha Oscillations Shape the Perception of Pain? - An EEG-based Neurofeedback Study
Pain is closely linked to alpha oscillations (8 -13 Hz) which are thought to represent a supra-modal, top-down mediated gating mechanism that shapes sensory processing.
- Trial name
- NCT05570695
- Testing
- attention right training, ARTNF, attention left training, ALTNF
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Alzheimer Disease, Working Memory
Induction and Stabilization of Gamma Oscillations With 40 Hz External Brain Stimulation
The goal of the present studies is to develop and validate novel stimulation protocols for the entrainment of gamma oscillations, which are associated with many cognitive functions and critically involved in cognitive impairment…
- Conditions
- Alzheimer Disease, Working Memory, EEG Brain Oscillations
- Trial name
- NCT06680154
- Testing
- Transcranial alternating current stimulation, Theta burst stimulation
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Epilepsy, Migraine
Clinical Applications of High-Frequency Oscillations
The objective of this study is to utilize high-frequency brain signals (HFBS) to localize functional brain areas and characterize HFBS in epilepsy, migraine, and other brain disorders.
- Conditions
- Epilepsy, Migraine, Headache, Pain
- Trial name
- HFOs (NCT00600717)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Epilepsies
Role of High-Frequency Oscillations on Scalp EEG in Identifying Epileptogenic Activity in Patients With Epilepsy and Healthy Controls
This observational case-control study aims to evaluate whether high-frequency oscillations (HFOs) detected on scalp electroencephalography (EEG) can differentiate patients with epilepsy from healthy controls.
- Trial name
- NCT07470931
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Gamma Oscillations, Healthy Adults
Investigating the Effectiveness of Personalized Optimal Gamma Auditory Frequency Stimulation Intervention on Cognitive Function Enhancement
This study aims to evaluate whether personalized gamma-frequency auditory stimulation enhances cognitive function and brain synchronization.
- Conditions
- Gamma Oscillations, Healthy Adults, Alzheimer's Disease (AD), Gamma Entrainment Using Sensory Stimuli (GENUS)
- Trial name
- NCT07690865
- Testing
- Personalized optimal gamma auditory frequency stimulation, Non-optimal gamma auditory frequency stimulation
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
fMRI Research, Transcranial Magnetic Stimilation
The Relationships Between Neural Correlates of Effort Perception and Physical Activity Engagement
Objectives and research hypothesis Physical inactivity is a major health concern that has been linked to a variety of chronic diseases, including obesity, diabetes, cancer, cardiovascular diseases, and mental disorders.
- Conditions
- fMRI Research, Transcranial Magnetic Stimilation, EEG Brain Oscillations, Motor Task
- Trial name
- EffortLESS (NCT06691490)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble