Clinical trials: EGD Procedure
Premalignant Conditions, Malignant Lesions
To Evaluate the Best Metric for Inspection Time During a Diagnostic and/or Surveillance Upper Gastrointestinal Endoscopy (Age ≥ 18 Years, Informed Consent), Between Total Inspection Time Versus Withdrawal Time, for the Identification of Malignant Lesions
Gastric cancer is the fifth cause of cancer-related mortality worldwide. Gastric carcinogenesis involves the progression from premalignant conditions such as atrophic gastritis and intestinal metaplasia to premalignant lesions…
- Conditions
- Premalignant Conditions, Malignant Lesions, Gastric, Esophageal
- Trial name
- NCT06696209
- Testing
- Analysis of the withdrawal time of the Upper Gastrointestinal Endoscopy, Analysis of the total time of the Upper Gastrointestinal Endoscopy, Upper gastrointestinal endoscopy: Common Practices
- Where
- Portugal
- Volunteers
- 1,290 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
EGD Procedure
Moderate Sedation for Elective Upper Endoscopy With Balanced Propofol Versus Propofol Alone: a Randomized Clinical Trial
Since introduction in 1989, propofol has gained wide acceptance for sedation during endoscopic procedures. The optimal sedation drug during esophagogastroendoscopy (EGD) is not established.
- Trial name
- NCT02174588
- Testing
- Midazolam + propofol, propofol
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yonsei University
SEDLine, Accoustic Respiratory Monitor RAD87
Incidence of Adverse Airway Events in High Risk Patients Undergoing Upper GI Endoscopy Under Anesthesia
We propose to collect the data of vital signs and anesthesia medications administered in a subcategory of patients coming for anesthesia for upper GI endoscopy.
- Conditions
- SEDLine, Accoustic Respiratory Monitor RAD87, Adverse Events, Advanced Endoscopic Procedures
- Trial name
- SEDLine (NCT02011607)
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- University of Pennsylvania
Primary Focus of the Study is Cost-minimization Analysis
Cost-Minimization Analysis After a Targeted Intervention for EGD and Colonoscopy
This study performs a single intervention of informing endoscopists how much the disposable accessories cost following each procedure.
- Trial name
- NCT02328001
- Testing
- Debriefing endoscopists of the procedure accessory costs
- Where
- United States
- Volunteers
- 969 people
- Sponsor
- Sindhu R Kaitha, MD
Aerosol-generating Procedure, Esophagogastroduodenoscopy
Esophagogastroduodenoscopy (EGD) is an Aerosol-generating Procedure: Proof of Concept Study
The disease COVID-19 has been classified as pandemic by World Health Organisation (WHO) in March 2020. This poses a risk to healthcare workers.
- Trial name
- NCT04400734
- Testing
- No intervention, observational study
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Anemia, Colon Polyps
Same Day Bidirectional Endoscopies - Does the Sequence of Procedures or Choice of Insufflator Matter?
Upper endoscopies (Esophagogastroduodenoscopies-EGDs) as well as a lower endoscopies (Colonoscopies) are routinely performed by gastroenterologists to assess the lining of patients' upper and lower gastrointestinal tracts using a…
- Trial name
- NCT02635217
- Testing
- Carbon dioxide insufflation, room air insufflation, EGD (Esophagogastroduodenoscopy) before Colonoscopy
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen's University
Esophagogastroduodensocopy (EGD) Procedure
The Effect of EGD Probe Insertion on the Intracuff Pressure of the Laryngeal Mask Airway or Cuffed Endotracheal Tube in Children
A prospective study designed to access changes in the intracuff pressure of a laryngeal mask airway (LMA) or cuffed endotracheal tube (cETT) during placement of an esophagogastroduodenoscopy (EGD) probe during an EGD in the…
- Trial name
- NCT02645019
- Testing
- Cuffed ETT, Cuffed LMA
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mineto Kamata
Capnography as an Adjunct to Standard Monitoring During Midazolam and Propofol Sedation for Interventional Upper GI Endoscopy
Capnography During Upper GI Endoscopy
In this randomized controlled trial the utility of capnography and IPI gets evaluated. Hypoxemia may occur during sedation with midazolam and propofol.
- Trial name
- NCT01242345
- Testing
- Capnography
- Where
- 3 sites in Germany
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
EGD Procedure
Case Series With Saneso 360° Gastroscope
To confirm the procedural performance of the Saneso 360° gastroscope in Esophago-gastro-duodenoscopy (EGD) procedures.
- Trial name
- NCT04621591
- Testing
- Saneso 360° gastroscope
- Where
- 6 sites in United States
- Volunteers
- 22 people
- Sponsor
- Saneso Inc.
Competency in General Endoscopic Surgical Procedures
Trial Evaluating Endoscopy Competence Among Gastroenterology Trainees in the Era of the Next Accreditation System.
Hypothesis: ACE (The Assessment in Competency in Endoscopy Tool) tool for colonoscopy and EGD (Esophagogastroduodenoscopy) allows for reliable standardized learning curves, competency benchmarks, and creation of a centralized…
- Trial name
- EnCompAS (NCT02891304)
- Testing
- Quarterly Feedback
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
C.Medical Procedure; Digestive System, Disorder of Upper Gastrointestinal Tract
Lidocaine Spray on an Endoscope to Improve Tolerance to Endoscopy
The investigators tested whether a new method which additional lidocaine spray on the tip of endoscope can increase the tolerance of examinee during endoscopy than conventional pharyngeal anesthesia alone.
- Conditions
- C.Medical Procedure; Digestive System, Disorder of Upper Gastrointestinal Tract, Tolerance
- Trial name
- NCT02307773
- Testing
- Case Group
- Where
- South Korea
- Volunteers
- 497 people
- Sponsor
- Cheju Halla General Hospital
Pain
Safety and Efficacy of Carbon Dioxide Insufflation During Colonoscopy With Consecutive Esophagogastroduodenoscopy in Reduction of Abdominal Pain in Sedated Outpatients
Compared with performing each procedure individually, performing two combined procedures such as colonoscopy consecutive Esophagogastroduodenoscopy (EGD) cause more bowel gases, abdominal distension and post-procedure pain…
- Trial name
- COCE (NCT01450202)
- Testing
- bowel insufflation gas
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Inje University
Procedural Sedation
A Safety Study of AQUAVAN® (Fospropofol Disodium) Injection for Sedation During Minor Surgical Procedures.
Very often patients receive medications before a diagnostic, therapeutic, or surgical procedure to help them relax, keep them calm, and to relieve them from pain. This is called procedural sedation.
- Trial name
- NCT00327392
- Testing
- AQUAVAN® (fospropofol disodium) Injection
- Where
- 15 sites in United States
- Volunteers
- 123 people
- Sponsor
- Eisai Inc.
Esophagogastroduodensocopy (EGD) Procedure
Ondansetron Combined with Dyclonine Hydrochloride to Improve Patient Experience in Unsedated Esophagogastro-duodenoscopy
The goal of this clinical trial is to learn if administering ondansetron prior to esophagogastroduodenoscopy (EGD) can alleviate the gagging reflex, nausea and vomiting in Chinese patients undergoing unsedated diagnostic EGD.
- Trial name
- NCT06729307
- Testing
- Oral ondansetron and dyclonine hydrochloride mucilage, Dyclonine hydrochloride mucilage
- Volunteers
- 260 people
- Sponsor
- Peking Union Medical College Hospital
Digestive System Diseases
Confocal Laser Endomicroscopy
Confocal laser endomicroscopy (CLE) is a new diagnostic technique that allows microscopic examination of the digestive mucosa during ongoing endoscopy.
- Trial name
- NCT00561938
- Testing
- Colonoscopy, Endoscopy
- Where
- 5 sites in France
- Volunteers
- 61 people
- Sponsor
- Nantes University Hospital
Esophagogastroduodenoscopy, Simethicone
Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy
The goal of this randomized, double-blind, placebo-controlled clinical trial is to assess whether the combination of N-acetylcysteine and simethicone improves mucosal visibility during upper gastrointestinal endoscopy in adults…
- Conditions
- Esophagogastroduodenoscopy, Simethicone, N-Acetylcysteine, Premedication
- Trial name
- NACSIMET (NCT07245095)
- Testing
- Premedication with n-acetylcysteine, Premedication with simethicone
- Where
- 2 sites in Mexico
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hospital General de Mexicali
Fasting, Gastric Emptying
Comparison of Residual Gastric Volume Between Children Who Drink Different Clear Oral Fluid Volume
According to the American Society of Anesthesiologists (ASA) fasting guideline for patients undergoing elective surgery, the 2-hour fasting period is suggested for clear oral fluid (including water, pulp-free juice and tea or…
- Trial name
- NCT03741777
- Testing
- Clear oral fluid
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Esophagogastroduodensocopy (EGD) Procedure
Oral Ondansetron to Improve Patient Experience of Unsedated Esophagogastroduodenoscopy Pilot Study
The goal of this interventional pilot study is to explore the feasibility of administering ondansetron prior to esophagogastroduodenoscopy (EGD), and preliminarily test if it can alleviate the gagging reflex, nausea and vomiting…
- Trial name
- NCT07264738
- Testing
- ondansetron and dyclonine hydrochloride, dyclonine hydrochloride only
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
Infection
Post-Endoscopic Infection Rate Notifications to Improve the Delivery of Care
This project will notify centers of center's post-endoscopic infection rates and evaluate the effectiveness of this notification system to decrease infection rates.
- Trial name
- NCT03922971
- Testing
- Option 1: National comparison, Option 2: National comparison with benchmarking
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- Johns Hopkins University
Conscious Sedation
Sedasys Post Approval Study Users Response to System Alarms
The purpose of this study is to evaluate the users' responses to the SEDASYS® System alarms during esophagogastroduodenoscopy (EGD) or colonoscopy.
- Trial name
- NCT02573818
- Testing
- SEDASYS System
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ethicon Endo-Surgery