Clinical trials: EGJ Outflow Obstruction
Achalasia, EGJ Outflow Obstruction
Safety and Efficacy of a Novel SpydrBlade Flexible Bipolar in POEM
Achalasia is an idiopathic motility disorder, primarily identified by the absence of esophageal peristalsis and the inability of the lower esophageal sphincter (LES) to relax properly.
- Trial name
- NCT07406945
- Testing
- SpydrBlade Flex
- Where
- 2 sites in Ecuador, Hong Kong
- Volunteers
- 73 people
- Sponsor
- Chinese University of Hong Kong
Type III Achalasia, EGJ Outflow Obstruction With Spastic/Hypercontractile Features
PREcision MEDicine In Achalasia (PREMEDIA) - Cohort
The goal of this observational study is to learn about how the doctor decides how long to cut t the esophageal muscle during Per-Oral Endoscopic Myotomy (POEM) in patients with difficulty swallowing due to certain conditions.
- Conditions
- Type III Achalasia, EGJ Outflow Obstruction With Spastic/Hypercontractile Features, Jackhammer Esophagus, Distal Esophageal Spasm
- Trial name
- PREMEDIA (NCT07293689)
- Where
- 16 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Type I Achalasia, Type II Achalasia
PREcision MEDicine In Achalasia (PREMEDIA)
The goal of this clinical trial is to learn if shorter Per-Oral Endoscopic Myotomy (POEM) works as well as a longer POEM in patients with trouble swallowing due to certain conditions.
- Conditions
- Type I Achalasia, Type II Achalasia, EGJ Outflow Obstruction Without Spastic/Hypercontractile Features
- Trial name
- PREMEDIA (NCT07293650)
- Testing
- Standard Myotomy, Tailored Short Myotomy
- Where
- 16 sites in United States
- Volunteers
- 372 people
- Sponsor
- Northwestern University