Clinical trials: EMBRYO IMPLANTATION
Astigmatism, Cataract
Limbal Relaxing Incision Versus Toric Intraocular Lens for Corneal Astigmatism During Cataract Surgery.
This study will compare toric intra-ocular lens (IOL) with limbal relaxing incisions (LRI) in correcting astigmatism in patient undergoing standard cataract surgery.
- Trial name
- NCT02067429
- Testing
- Limbal Relaxing Incisions, Toric Intraocular Lens
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Christin Henein
Aortic Stenosis
A Clinical Trial of the Transcatheter Aortic Valve Implantation System With a Prospective, Multi-Center, One-Arm Approach to Evaluate the Efficacy and Safety in the Treatment of Patients With Severe Aortic Stenosis
A Clinical Trial of the Transcatheter Aortic Valve Implantation System with a Prospective, Multi-Center, One-Arm Approach to Evaluate the Efficacy and Safety in the Treatment of Patients with Severe Aortic Stenosis
- Trial name
- NCT05673525
- Testing
- Transcatheter Aortic Valve Implantation (KOKA-VALVE)
- Where
- China
- Volunteers
- 131 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Defibrillators, Implantable
Patient Expectations After Implantable-cardioverter Defibrillator (ICD) Implantation
This study will be a qualitative survey to understand the expectations of defibrillator patients with regards to their device. It is unknown what ICD (implantable-cardioverter defibrillator) patients understand about their device…
- Trial name
- NCT00845390
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Heart Failure, Myocardial Infarction
Prophylactic Substrate Ablation in Post-myocardial Patients Undergoing Defibrillator Implantation.
Prophylactic substrate ablation in post-MI patients undergoing defibrillator implantation reduces appropriate defibrillator therapies.
- Conditions
- Heart Failure, Myocardial Infarction, Ventricular Tachycardia
- Trial name
- NCT02780947
- Testing
- Ventricular tachycardia substrate ablation
- Volunteers
- 40 people
- Sponsor
- Spyridon Deftereos
Sensorineural Hearing Loss
Immunity After Cochlear Implantation and Perilymph Molecular Profiles in Sensorineural Hearing Loss
Many patients receiving cochlear implant (CI) have some residual hearing prior to implantation surgery. However, approximately one third of them will lose it in next 6 months after cochlear implantation.
- Trial name
- PERILOTO (NCT05670158)
- Testing
- Blood sampling, Perilymph sampling
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Acute Myocardial Infarction, Persisting Ischemia
Intra-aortic Balloon Pump in Extensive Myocardial Infarction With Persistent Ischemia
Patients presenting with large myocardial infarction and signs of persistent ischemia after successful percutaneous coronary intervention, have a poor prognosis with respect to outcome and development of heart failure in the…
- Conditions
- Acute Myocardial Infarction, Persisting Ischemia, No Reflow
- Trial name
- SEMPER FI (NCT02125526)
- Testing
- Intra-aortic balloon pump
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Lokien van Nunen
Invitro Fertilization
Endometrial Injury and Implantation Rates Before First ICSI Cycle
Midluteal single endometrial strip will be taken using a Novak curett under general anasthesia to avoid discomfort and cramping and to proceed to cervical dilatation in case of forbidden cervix, the step that will be beneficial…
- Trial name
- NCT02660125
- Testing
- Endometrial scratch injury
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Cairo University
Foramen Ovale, Patent
Patent Foramen Ovale (PFO) Closure at the Time of Endovascular Cardiac Electronic Device Implantation
Participants enrolled in this study will have been diagnosed with patent foramen ovale (PFO) and have been scheduled to have a cardiovascular implantable electronic device (CIED) such as a pacemaker, implantable…
- Trial name
- PFOCUS (NCT03232450)
- Testing
- Aspirin, Cardiovascular Implantable Device (CIED), Gore Cardioform Septal Occluder
- Where
- United States
- Sponsor
- Mayo Clinic
Cataract, Presbyopia
A Randomised Evaluation of Visual Function After Bilateral Implantation of Two Types of Presbyopia-correcting IOLs
Since the introduction of intraocular lenses (IOL) in the treatment of cataract, the postoperative accommodative loss of the human eye has been a trending topic.
- Trial name
- NCT03117426
- Testing
- SYMFONY IOL, AT LISA tri 839MP IOL
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cartilage Diseases, Osteoarthritis
Human Umbilical Cord Mesenchymal Stem Cell Transplantation in Articular Cartilage Defect
The purpose of this study is to evaluate the safety and efficacy of human umbilical cord mesenchymal stem cell(hUC-MSC) for articular cartilage defect of knee.
- Trial name
- NCT02291926
- Testing
- Human umbilical cord mesenchymal stem cells
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shenzhen Hornetcorn Bio-technology Company, LTD
Coronary Artery Disease
OPTImal Management of Antithrombotic Agents: OPTIMA-2 Trial
High on-treatment platelet reactivity (HOPR) is associated with increased risk of cardiovascular events in patients undergoing percutaneous coronary intervention (PCI).
- Trial name
- OPTIMA-2 (NCT01955200)
- Testing
- Clopidogrel, Cilostazol, Ticagrelor
- Where
- China
- Volunteers
- 1,724 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Ascites, Paracentesis
Medical-economic Evaluation of the Care of Refractory Ascites by Implantation of Alfapump® Device in Cirrhotic Patients
The hypothesis is that the Alfapump® strategy would be more effective in terms of QALYs generated , and that the cost of Alfapump® device and its implantation will be totally or partially offset by the reduction in the number of…
- Conditions
- Ascites, Paracentesis, Cirrhosis
- Trial name
- ARIAPUMP (NCT03506893)
- Testing
- Alphapump, Ascites puncture
- Where
- 10 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Grenoble
Blastocyst, Implantation Rate
Sperm DNA Fragmentation Effects on Blastocyst Morphology Grading, Pregnancy Rate and Implantation Rate
Retrospective cohort study for 189 couples assigned to normal and abnormal Sperm DNA fragmentation (SDF) groups.To determine the effect of SDF on blastocyst's trophectoderm (TE), Inner cell mass (ICM) morphology grading, and…
- Trial name
- NCT04144621
- Testing
- ICSI
- Where
- Egypt
- Volunteers
- 189 people
- Sponsor
- Ganin Fertility Center
Acute Coronary Syndromes, Percutaneous Coronary Intervention
Effects of Intensive Antiplatelet Therapy for Patients With Clopidogrel Resistance After Coronary Stent Implantation
Clopidogrel resistance (CR) or low-responsiveness is associated with increased risk of ischemic events and can be detected by laboratory tests.
- Conditions
- Acute Coronary Syndromes, Percutaneous Coronary Intervention, Clopidogrel Low Responsiveness
- Trial name
- NCT01094457
- Testing
- aspirin, clopidogrel, aspirin, clopidogrel, cilostazol
- Where
- 3 sites in China
- Volunteers
- 840 people
- Sponsor
- Shenyang Northern Hospital
Microspherophakia
The Efficacy of a 6-point Transscleral Suture Fixation of a 3-looped Haptics PC-IOL Implantation Through Scleral Pockets for Surgical Management for Microspherophakia
By comparing the preoperative data and postoperative data of 9 patients of microspherophakia, we concluded that the 6-point transscleral suture fixation of a 3-looped haptics posterior chamber intraocular lens (PC-IOL) through…
- Trial name
- NCT04447157
- Volunteers
- 9 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Coronary Artery Disease, Angina Pectoris
Comparison of Cypher Select and Taxus Express Coronary Stents
Randomized nine months clinical comparison of implantation of Taxol eluting (Taxus Express) and Sirolimus eluting (Cypher Select) stents in non-selected patients with coronary artery disease.
- Trial name
- SORT-OUTII (NCT00388934)
- Testing
- Drug eluting stent
- Volunteers
- 2,095 people
- Sponsor
- Aarhus University Hospital Skejby
Parkinson's Disease, Dystonia
Use of Interventional MRI for Implantation of Deep Brain Stimulator Electrodes
The purpose of this study is to gather observational data on an already FDA-approved implantation technique for deep brain stimulation (DBS) in which the entire surgery is performed within an MRI scanner ("interventional MRI", or…
- Trial name
- iMRI (NCT00792532)
- Testing
- interventional MRI for implantation of DBS electrodes, DBS electrodes
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, San Francisco
Liver Cirrhosis, Ascites Hepatic
Early TIPS in Patients With Liver Cirrhosis and Ascites
The aim of this clinical trial is to compare the safety and efficacy of transjugular intrahepatic portosystemic shunt (TIPS) implantation with standard treatment (diuretic medications, and if necessary, paracenteses) in patients…
- Conditions
- Liver Cirrhosis, Ascites Hepatic, Portal Hypertension
- Trial name
- eTIPS (NCT06576934)
- Testing
- Transjugular intrahepatic portosystemic shunt (TIPS)
- Where
- Germany
- Volunteers
- 134 people
- Sponsor
- University Hospital Freiburg
Coronary Artery Disease, Myocardial Ischemia
Primary FIbrinolysis and Secondary STenting Versus immEdiate Stenting in ST-segment Elevation Myocardial Infarction
This prospective, multicenter, randomized, controlled, open-label clinical study has a target enrollment of 240 subjects. It will explore whether STEMI patients transferred to a PCI center following thrombolytic therapy and…
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Acute Coronary Syndrome, Heart Diseases
- Trial name
- FISSTEMI (NCT04663932)
- Testing
- immediate stenting group(one-step strategy), deferred stenting group (two-step strategy)
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Harbin Medical University
Infertility
Implantation and Cytokine Expression
Implantation failure of the embryo might be the result from the environment in the uterus. Proteins (cytokines) are screted by the endometrium which can result in a pro or anti inflammatory environment.
- Trial name
- NCT00264992
- Where
- Netherlands
- Volunteers
- 160 people
- Sponsor
- UMC Utrecht
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