Clinical trials: EMERGENCY MEDICINE
Emergency Medicine, Telemedicine
Integration of the 5G-based Remote Healthcare System in Critical Care
The primary objective of this initial report is to address the following questions: Under what circumstances do clinical teams at satellite locations utilize the 5G RHS? Does the implementation of 5G RHS result in significant…
- Conditions
- Emergency Medicine, Telemedicine, Augmented Reality
- Trial name
- IT5GRHSCI (NCT06485518)
- Testing
- The 5G RHS group receiving audio-video conferencing and effective data management for decision-making via augmented reality platform RealHealthcare System.
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Sir Run Run Shaw Hospital
Status Asthmaticus
The Role of Ketamine as an Adjuvant Therapy for Children With Acute Status Asthmaticus
The purpose of this investigation is to perform a pilot study assessing the safety and utility of intravenous ketamine as an adjuvant therapy in the emergency department setting for pediatric patients in acute status asthmaticus…
- Trial name
- NCT03338205
- Testing
- Ketamine
- Sponsor
- Augusta University
Acute Cardiovascular, Pneumonia
Evaluation of Lung Doppler Signals in Patients Presenting to EMD
Historically, ultrasound has been unable to provide interpretable data from the lung parenchyma, mainly because of the high total ultrasound energy attenuation and scattering by the air in the lungs.
- Conditions
- Acute Cardiovascular, Pneumonia, Pulmonary Embolism, CHF Exacerbation
- Trial name
- NCT01961141
- Where
- Israel
- Sponsor
- Echosense Ltd.
Anesthesia, Hypoxia
Assessment of Preoxygenation Strategies in the Prehospital Environment
Comparison of the preoxygenation efficacy of tidal volume breathing using three different preoxygenation techniques which are available to providers in the prehospital environment.
- Trial name
- NCT02694705
- Testing
- Continuous Positive Airway Pressure (CPAP), Bag-Valve-Mask (BVM), Non-rebreather Mask (NRM)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Children, Lacerations
Pain and Anxiety Management With Oral Narcotic for Pediatric Suture Repair
The purpose of this study is: To determine whether oral narcotic medication versus placebo improves the pain and anxiety scores for pediatric patients requiring laceration repair in the pediatric emergency department and…
- Conditions
- Children, Lacerations, Procedures, Child
- Trial name
- NCT01053637
- Testing
- hydrocodone/acetaminophen, Sugar water
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Baylor College of Medicine
Trauma
SWiFT Canada (Study of Whole Blood in Frontline Trauma)
Traumatic injuries affect people of all ages, races, and socioeconomic backgrounds. The Global Burden of Disease study showed that globally in 2019, there were more than 4.4 million deaths due to injury.
- Trial name
- SWiFTCanada (NCT06495294)
- Testing
- Whole Blood, RBC + plasma
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Unity Health Toronto
Sepsis, Device Performance
PIVO Use for Blood Cultures in the Emergency Department
The investigators will implement a protocol for use of the PIVO device for blood culture collection in the emergency department.
- Conditions
- Sepsis, Device Performance, Emergency Medicine
- Trial name
- PIVO-ED (NCT07348289)
- Testing
- PIVO device, a needle-free blood draw device
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Intermountain Health Care, Inc.
Emergency
Variation IGFBP7 Markers and TIMP2 Induced by Injection of Contrast Iodized Drug at the Intensive Care Patient
Multicenter, prospective, uncontrolled study to evaluate variations in urinary concentrations of TIMP-2 and PCI IGFBP7 induced injection during a CT scan in intensive care patient.
- Trial name
- ContraCHECK (NCT02881710)
- Testing
- contrast product used to assess biomarkers variations
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Medical Education, Emergency Medicine
Comparison of Task Trainer and Virtual Reality Approaches in Dysrhythmia Management Education
The aim of this randomized controlled simulation-based educational study was to compare the effectiveness of virtual reality (VR)-based and task trainer-based training in improving dysrhythmia management performance among intern…
- Conditions
- Medical Education, Emergency Medicine, High-Fidelity Simulation Training, Virtual Reality Simulation
- Trial name
- NCT07892391
- Testing
- Virtual Reality-Based Dysrhythmia Management Training, Task Trainer-Based Dysrhythmia Management Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Operational Metrics of the Emergency Department
Prospective Evaluation of Computerized Physician Order Entry in the Emergency Department
This study will evaluate various performance metrics of emergency department operations after the implementation of computerized physician order entry in an academic emergency department.
- Trial name
- CPOE (NCT01444768)
- Testing
- Computerized Physician Order Entry
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
Acute Coronary Syndrome, Myocardial Infarction (MI)
Clinical Echocardiography and S' Wave for Early Recognition of Acute Coronary Syndrome in the Emergency Department, A Prospective Study
The goal of this prospective observational study is to assess the diagnostic accuracy of the tissue Doppler imaging (TDI) S' wave in detecting acute coronary syndrome (ACS) in adult patients presenting to the emergency department…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction (MI), Non-ST Elevation Myocardial Infarction, Unstable Angina
- Trial name
- CLEAR_ECHO (NCT06860997)
- Testing
- Tissue Doppler Imaging (TDI) S' Wave Echocardiography
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Acute Pain
A Randomized Trial of Behavioral Economic Approaches to Reduce Unnecessary Opioid Prescribing
In this study, the investigators will evaluate the effect of a health system initiative aiming to change clinician opioid prescribing behaviors using two behavioral economic interventions - individual audit feedback and peer…
- Trial name
- REDUCE (NCT03825549)
- Testing
- Individual audit feedback, Peer comparison feedback
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Need to Refer the Patient to the Hospital Emergency Department
Artificial Intelligence Triage of Patients Requiring Emergency or Unscheduled Care Who Need to be Referred to Hospital
For several decades, hospital emergency departments have been experiencing congestion, sometimes reaching saturation point, where they are no longer able to fulfil their primary mission: to prioritise patients requiring immediate…
- Trial name
- TRIAGE (NCT07428109)
- Where
- France
- Volunteers
- 40,680 people
- Sponsor
- SOS Médecins Grand Paris
Drug Overdose, Opioid-Related Disorders
Safety & Prevention Outcomes Study
Unintentional poisoning is a developing public health problem in the U.S. Unintentional poisoning (or "overdose") deaths increased 157% among adults between 1999 and 2008.
- Trial name
- SPOS (NCT01894087)
- Testing
- TBI - Cohort 1, TBI - Cohort 2
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- University of Michigan
Abdominal Pain (AP), Acute Abdomen
Emergency Medicine Evaluation for Acute Abdominal Pain - a Pragmatic Randomized Trial
The goal of this clinical trial is to learn whether initial assessment by a physician specializing in emergency medicine can improve the care of adults who come to the emergency department with acute abdominal pain or another…
- Conditions
- Abdominal Pain (AP), Acute Abdomen, Acute Abdominal Pain, Abdomen, Acute
- Trial name
- EMERGE-Abdomen (NCT07815795)
- Testing
- Emergency Medicine Initial Assessment, Standard Surgical Assessment
- Where
- Norway
- Volunteers
- 440 people
- Sponsor
- Haukeland University Hospital
Discrimination, Racial, Pain Management
Opioid Prescribing in the Emergency Department for Sickle Cell Disease
This study consists of a clinical vignette presented to emergency physicians asking them what they would prescribe to a patient with acute abdominal pain.
- Conditions
- Discrimination, Racial, Pain Management, Emergency Medicine, Sickle Cell Disease
- Trial name
- DOPED-SCD (NCT06835335)
- Testing
- opioid prescription
- Where
- 2 sites in France, United Kingdom
- Volunteers
- 1,063 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Sepsis, Severe Sepsis
Protocolized Care for Early Septic Shock
The ProCESS study is large, 5-year, multicenter study of alternative resuscitation strategies for septic shock. The study hypothesizes that there are "golden hours" in the initial management of septic shock where prompt…
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- ProCESS (NCT00510835)
- Testing
- Early Goal Directed Therapy (EGDT), Protocolized Standard Care (PSC), Usual Care (UC)
- Where
- 31 sites in United States
- Volunteers
- 1,351 people
- Sponsor
- University of Pittsburgh
Renal Colic, Hydronephrosis
Emergency Department Ultrasound in Renal Colic
Renal colic is a common (1300 visits per year at our institution) and painful condition caused by stones in the kidney and ureter, and can be mimicked by life threatening conditions such as a ruptured abdominal aortic aneurysm…
- Conditions
- Renal Colic, Hydronephrosis, Abdominal Aortic Aneurysm
- Trial name
- NCT01323842
- Testing
- EDTU
- Where
- Canada
- Volunteers
- 414 people
- Sponsor
- Queen's University
Hypertensive Emergency
Clinical Study of Clevidipine Butyrate Injection in the Treatment of Hypertensive Emergency and Sub-emergency
Emergency treatment warning of clevidipine butyrate butyrate injection or invalid medical treatment and verification of the effectiveness and safety of subacute.
- Trial name
- NCT05044364
- Testing
- This is a randomized, single-blind, parallel-controlled clinical study with the original research clevidipine butyrate injection as the positive control drug, which is an equivalence test.
- Where
- 2 sites in China
- Volunteers
- 10 people
- Sponsor
- Shenzhen People's Hospital
Respiratory Failure
HEAVEN Criteria: Prediction of Difficult Airway for In- Hospital Emergency Airway Management
The HEAVEN criteria were found valid to predict difficult airways during preclinical emergency intubations in a retrospective study.
- Trial name
- NCT04764799
- Testing
- Rapid sequence induction
- Where
- Switzerland
- Volunteers
- 2,800 people
- Sponsor
- Thomas Riva