Clinical trials: EMERGENCY MEDICINE
EMERGENCY MEDICINE
Prevalence of Chronic Pain After an Emergency Department Visit for Severe Acute Pain
The main objective for investigators is to determine the prevalence of moderate to severe chronic pain in the adult population 6 months after consultation in the emergency department for acute pain (less than 7 days old) and…
- Trial name
- CHROPAIN (NCT04625374)
- Where
- 2 sites in France
- Volunteers
- 495 people
- Sponsor
- University Hospital, Grenoble
Emergency Medicine
Development of a Multipurpose Dashboard to Monitor the Situation of Emergency Departments
An emergency department (ED) is a healthcare service that provides the first clinical assessment and treatment to patients with various acute conditions.
- Trial name
- eCREAM-UC2 (NCT06372379)
- Testing
- no intervention
- Where
- 2 sites in Italy
- Volunteers
- 162,000 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Fall, Fall Accident
The Geriatric Emergency Department Pharmacologic Harm Prevention Project
The goal of this project is to determine whether pharmacogenomic testing (using participants' DNA) can help optimize medication prescribing and reduce side effects in older adults taking five or more medications.
- Conditions
- Fall, Fall Accident, Poly Pharmacy, Adverse Drug Events
- Trial name
- GREAT PHARM (NCT07216846)
- Testing
- DNA care pathway
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Florida Atlantic University
Health Related Social Needs (HRSN), Pharmacy
Pharmacist-Led SDoH Screening Intervention During Transitions of Care in an Acute Care Setting
The study is a quasi-experimental pilot study conducted at Buffalo General Medical Center (BGMC). It aims to evaluate the feasibility, acceptability, and effectiveness of a pharmacist-led intervention addressing health-related…
- Conditions
- Health Related Social Needs (HRSN), Pharmacy, Medication Reconciliation
- Trial name
- NCT06802393
- Testing
- Intervention
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- State University of New York at Buffalo
Acute Musculoskeletal Pain
Virtual Reality and Standard Care vs. Standard Care Alone for Acute MSK Pain in Geriatric ED Patients
The proposed Virtual Reality as an Adjunct to Pain Management for Geriatric Patients in the ED (VRAP-ED) project will take place in the Emergency Medicine Department at Maimonides Medical Center.
- Trial name
- NCT06685107
- Testing
- Standard of Care Analgesia, Standard of Care Analgesia + Virtual Reality
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Antonios Likourezos
Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple
AI Assisted Detection of Chest X-Rays
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple, Pulmonary Consolidation, Pneumothorax
- Trial name
- AID-CXR (NCT06075836)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Emergency Department
Improving Quality & Equity of Emergency Care Decisions (IQED)
Recent work in emergency medicine has shown errors were more likely to occur at the end of shifts, as pressure exists to make a number of decisions simultaneously, and after what may be an already long series of cognitive…
- Trial name
- IQED (NCT03966989)
- Testing
- Performance Feedback
- Where
- 4 sites in United States
- Sponsor
- University of Southern California
Acute Coronary Syndrome
Rapid Assessment of Potential Ischaemic Heart Disease With CTCA
This study aims to investigate the effect of early CTCA in patients with suspected or confirmed Acute Coronary Syndrome (ACS) presenting to the Emergency Department (ED) or Medical Assessment Unit (MAU), upon interventions, event…
- Trial name
- RAPID-CTCA (NCT02284191)
- Testing
- CT Coronary Angiogram
- Where
- 37 sites in Jersey, United Kingdom
- Volunteers
- 1,749 people
- Sponsor
- University of Edinburgh
COVID19
Nitric Oxide Inhalation Therapy for COVID-19 Infections in the ED
The spread of novel Coronavirus (2019-nCoV) related infection (COVID-19) has led to many patient presentations in the emergency department for respiratory complaints, with many of these patients requiring ICU admission and…
- Trial name
- NO COV-ED (NCT04338828)
- Testing
- Nitric Oxide Gas, Inhaled Supplemental Oxygen
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Massachusetts General Hospital
COPD
Palliative Care Health Literacy Education and QOL Compared to Usual Care
The goal of this pilot randomized controlled trial is to compare health literacy (HL) and quality of life (QOL) among older adults with chronic obstructive pulmonary disease (COPD) who completed a series of standardized…
- Trial name
- PACED (NCT06089499)
- Testing
- Get Palliative Care: four educational learning module videos
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Syncope
Syncope Decision Aid for Emergency Care
Syncope, or transient loss of consciousness/fainting, is a common emergency department (ED) complaint responsible for over 1 million ED visits yearly.
- Trial name
- SynDA (NCT02971163)
- Testing
- SynDA
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Stroke.
Prehospital Stroke Study at the Universitair Ziekenhuis Brussel I (PreSSUB I)
The PreSSUB trial I will focus on prehospital telemedicine for patients with suspicion of acute stroke. The study is designed as a prospective monocentric observational trial on the safety, feasibility and reliability of…
- Trial name
- PreSSUB I (NCT02230852)
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Emergency Medicine
Assessing Mixed Reality for Emergency Medical Care Delivery in a Simulated Environment
This study assessed the feasibility and effectiveness of using Mixed Reality (MR) through the use of HoloLens2TM technology to enhance emergency clinical care delivery in a simulated environment.
- Trial name
- NCT05870137
- Testing
- HoloLens2TM, Standard care
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Imperial College London
HIV Infections, Breast Cancer
The MARVIN Chatbots to Provide Information for Different Health Conditions
This research is a continuation of a usability study with the MARVIN chatbot. The investigators aim to adapt the MARVIN chatbot to open it to other health domains (e.g. breast cancer) and populations (e.g. pharmacists).
- Conditions
- HIV Infections, Breast Cancer, Pediatric Emergency Medicine
- Trial name
- NCT05789901
- Testing
- MARVIN, MARVIN-Pharma, MARVINA
- Where
- 2 sites in Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Status Epilepticus, Non-Convulsive Status Epilepticus
Point-of-care EEG in the Pediatric Emergency Department
The researchers investigate the use of a simplified electroencephalogram (point-of-care EEG) in the pediatric emergency department for children with impaired consciousness or an ongoing epileptic seizure ("status epilepticus").
- Conditions
- Status Epilepticus, Non-Convulsive Status Epilepticus, Altered Mental Status
- Trial name
- NCT05418634
- Testing
- point of care EEG
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Children's Hospital, Zurich
Ebola Virus Disease
An Open Study of the Safety and Pharmacokinetics of a Drug for the Emergency Prevention of Ebola Virus Disease
Open-label safety, tolerability, pharmacokinetics and immunogenicity study in three dose escalation groups
- Trial name
- NCT04717830
- Testing
- Gamezumab
- Where
- Russia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Non-traumatic Low Back Pain
Comprehensive Biopsychosocial Approach for Acute Low Back Pain Management in the Emergency Department: a Stepped-wedge Cluster-randomized Clinical Trial
Acute low back pain, the second leading cause of medical consultations in France, poses a major public health challenge, particularly because of its high risk of progressing to chronic low back pain-the leading cause worldwide of…
- Trial name
- CALM-ED (NCT07375914)
- Testing
- Biopsychosocial intervention
- Where
- France
- Volunteers
- 782 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Emergencies
Primary Palliative Care for Emergency Medicine (PRIM-ER)
This proposal builds upon the evaluation of Primary Palliative Care Education, Training, and Technical Support for Emergency Medicine (PRIM-ER) implemented in a cluster-randomized, stepped wedge design in 33 Emergency Departments…
- Trial name
- NCT03424109
- Testing
- healthcare service utilization in the six months following the ED visit
- Where
- United States
- Volunteers
- 98,922 people
- Sponsor
- NYU Langone Health
Nausea, Vomiting
Value of Ondansetron Medication vs Inhaled Isopropyl Therapy in the Emergency Department (VOMIITED)
This study will compare two different ways to relieve nausea and vomiting in the Emergency Department. The usual treatment for nausea/vomiting is a drug called Zofran, but new studies have suggested that smelling alcohol pads can…
- Trial name
- VOMIITED (NCT03125811)
- Testing
- Inhaled Isopropyl Alcohol (IPA), Oral Dissolvable Tablet Zofran (ondansetron)
- Where
- 2 sites in United States
- Volunteers
- 121 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Otitis Media, Urinary Tract Infection
ParentLink: Better and Safer Emergency Care for Children
The emergency department (ED) constitutes a high-risk environment for errors and poor quality of care. Pediatric patients are at increased risk of medical errors.
- Conditions
- Otitis Media, Urinary Tract Infection, Asthma, Head Injury
- Trial name
- NCT00457600
- Testing
- patient-driven health IT product
- Where
- 2 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Boston Children's Hospital