Clinical trials: ESBL-producing Enterobacteriaceae Infections
Escherichia Coli Infections, Klebsiella Pneumonia
Colonization With Extended-Spectrum Beta-Lactamase (ESBL)-Producing Organisms
There has been a great increase in the incidence of infections caused by bacteria that are resistant to antibiotic agents. Many of these infections result in worse outcomes of patients and increased costs to the healthcare…
- Trial name
- NCT01324726
- Where
- Lebanon
- Volunteers
- 100 people
- Sponsor
- American University of Beirut Medical Center
Quinolone Resistance, ESBL
Risk Factors for Quinolone Resistance Among ESBL Producing Klebsiella Species
This is a retrospective chart review. This proposed study aims to document the risk factors for quinolone resistance in bloodstream isolates of Klebsiella species.
- Conditions
- Quinolone Resistance, ESBL, Klebsiella Species, Infection
- Trial name
- NCT00518661
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Pittsburgh
Enterobacteriaceae Infections
The Prevalence of Extend-Spectrum β-Lactamase (ESBL) Producing Isolates Among Common Enterobacteriaceae in Taiwan
Resistance to broad-spectrum cephalosporins through the acquisition and expression of Extended-Spectrum β-lactamase (ESBL) among Enterobacteriacea is increasing.
- Trial name
- NCT01725841
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Urinary Tract Infection Bacterial
Temocillin Versus Carbapenems for Urinary Tract Infection Due to ESBL-producing Enterobacteriaceae
To assess the efficacy of temocillin compared to carbapenems for the management of ESBL-E UTI.
- Trial name
- TEMO-BLSE (NCT04671290)
- Testing
- Any intervention
- Volunteers
- 144 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Urinary Tract Infections
Clinical Efficacy of Fosfomycin Trometamol Per os in the Treatment of Documented Male Urinary Tract Infections With ESBL-producing Enterobacteriaceae With ESBL Producing Enterobacteriaceae and Resistance Associated With Fluoroquinolones and Cotrimoxazole (FOSF'HOM)
The aim of the study was to evaluate the clinical and microbiological efficacy of fosfomycin trometamol (FT) per os in the treatment of documented male urinary tract infections with ESBL-producing enterobacteriaceae
- Trial name
- FOSF'HOM (NCT03868969)
- Testing
- Fosfomycin Oral Suspension
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
E Coli Infection, ESBL Producing E.Coli
Cefotetan Therapy for Escherichia Coli Infections
This pilot study will compare clinical outcomes among patients treated with cefotetan versus standard of care antibiotics for bacteremia caused by E. coli.
- Trial name
- NCT07318584
- Testing
- Cefotetan, Carbapenems, Beta Lactam Antibiotics
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Oregon Health and Science University
Urinary Tract Infection
Temocillin Use in Complicated Urinary Tract Infections Due to Extended Spectrum Beta-Lactamases (ESBL)/AmpC Enterobacteriaceae
This study is aimed at demonstrating the efficacy of temocillin in the treatment of complicated Urinary Tract Infection (UTI) due to confirmed Extended Spectrum Beta-Lactamases (ESBL) producing or AmpC hyperproducing…
- Trial name
- TEA (NCT01543347)
- Testing
- Temocillin
- Where
- United Kingdom
- Sponsor
- Belpharma s.a.
Bacteremia
Recurrent ESBL-producing Enterobacteriaceae Bacteremia: Risk Factor, Molecular Character and Susceptibility Change
The purpose of this study is to investigate the risk factor, molecular character and susceptibility change for recurrent ESBL-producing Enterobacteriaceae bacteremia
- Trial name
- NCT01392118
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Chang Gung Memorial Hospital
Enterobacteriaceae Infections
Epidemiology of Community - Associated Extended-spectrum Beta-lactamases (ESBL) Producing Escherichia Coli
The purpose of this study is to review patients with E. coli infections at the University of Pittsburgh Medical Center (UPMC) from July 1, 2007 to June 30, 2010 to determine if these infections have arisen in the community rather…
- Trial name
- NCT00573235
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
Urinary Infection, Digestive Infection
Deescalating Carbapenems in Hospital Setting
The study aims to evaluate a deescalating therapeutic strategy (switch the carbapenem to another beta-lactam for which the isolated pathogen is susceptible) in patients with well-defined ESBL-PE infections (usual sites of…
- Conditions
- Urinary Infection, Digestive Infection, Biliary Infection, Expanded-spectrum Beta-lactamase Producing ESBL
- Trial name
- CARBEPARGNE (NCT02265445)
- Testing
- Deescalation therapy, Maintaining carbapenem therapy
- Volunteers
- 6 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cancer
Controling Intestinal Colonization With Extended Spectrum ß-Lactamase Producing Enterobacteriaceae ESBL-E
Rapid and rational health-care interventions are of great importance to efficiently combat the emergence of resistant and virulent bacteria. In recent years, spread of ESBL-E on a global level has been observed.
- Trial name
- CLEAR (NCT01931592)
- Testing
- ESBL eradication regimen
- Where
- 2 sites in Germany
- Volunteers
- 29 people
- Sponsor
- Maria J.G.T. Vehreschild
ESBL-producing Enterobacteriaceae Infections
Factors Influencing the Fecal Relative Abundance of ESBL-producing Enterobacteriaceae in Intensive Care (BLSE-REA).
Extended-Spectrum Beta-Lactamases (ESBL)-Producing Enterobacteriaceae (PE) pose a major problem among antimicrobial resistance. The worldwide spread of theses bacteria may be responsible for 10 million death in 2050.
- Trial name
- NCT04190316
- Testing
- Evaluation of fecal RA and environmental contamination of ESBL-PE carrier in ICU
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Urinary Tract Infections
Efficacy of Temocillin in Urinary Tract Infection Due to ESBL Producing and AmpC Hyperproducing Enterobacteriaceae
The present study aims at demonstrating the efficacy of temocillin in the treatment of UTI requiring parenteral therapy due to a confirmed ESBL producing or AmpC hyperproducing Enterobacteriaceae, resistant to quinolones and…
- Trial name
- TEMO-ESBL (NCT02681263)
- Testing
- Temocillin
- Where
- 19 sites in France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Grenoble
Urinary Tract Infections, Enterobacteriaceae Infections
Piperacillin/Tazobactam Versus Carbapenems in Non-bacteremic UTI Due to -ESBL-producing Enterobacteriaceae
This study evaluates the efficacy in achieving clinical cure in non-bacteremic urinary tract infections (UTI) caused by Escherichia coli or Klebsiella pneumoniae producers of extended-spectrum β-lactamases (ESBL) in adult…
- Conditions
- Urinary Tract Infections, Enterobacteriaceae Infections, Infection Due to ESBL Bacteria, Carbapenem
- Trial name
- CAPITIS (NCT03891433)
- Testing
- Meropenem, Ertapenem 1000 MG, Piperacillin, Tazobactam 4-0.5G Solution for Injection
- Where
- Colombia
- Volunteers
- 198 people
- Sponsor
- Universidad del Norte
Premature Rupture of Membranes, Enterobacteriaceae
Prevalence of Carriage of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacteria in Preterm Premature Rupture of Membranes : A French Multicenter Cohort Study
This study looks at how common certain antibiotic-resistant bacteria (called extended-spectrum beta-lactamase-producing Enterobacteriaceae, or E-BLSE) are in pregnant women who experience premature breaking of their water before…
- Conditions
- Premature Rupture of Membranes, Enterobacteriaceae, Beta-Lactams, Drug Resistance, Bacterial
- Trial name
- NCT07200999
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier de Saint-Denis