Clinical trials: EUS
Pancreatic Adenocarcinoma
The Impact Of Tissue Micro-RNA Profile From EUS-FNA In Pancreatic Adenocarcinoma
Pancreatic adenocarcinoma still represents one of the "hot-topics" worldwide. Endoscopic ultrasonography was a breakthrough, bringing us closer to personalized treatment by getting histopathological samples through…
- Trial name
- EUS-FNA (NCT04765410)
- Testing
- EUS FNA (endoscopic ultrasound fine needle aspiration)
- Where
- 5 sites in Romania
- Volunteers
- 57 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Jaundice
Prospective Randomized Study of PTC and EUS-guided Drainage of the Bile Duct
At this time, endoscopic retrograde cholangiopancreatography (ERCP) stay the gold standard method to achieve biliary drainage in case of malignant or benign stricture.
- Trial name
- NCT01499537
- Testing
- biliary drainage, EUS guided biliary drainage
- Where
- 3 sites in France, Monaco
- Volunteers
- 65 people
- Sponsor
- Institut Paoli-Calmettes
Cholelithiasis
Cholecystectomy vs EUS-guided GBD With Stone Removal
In this new era of less invasive procedures, the indications for endoscopic ultrasound (EUS)-guided gallbladder drainage (GBD) are rapidly expanding.
- Trial name
- NCT06038201
- Testing
- LAMS placement for cholecystostomy, Laparoscopic cholecystectomy
- Where
- Ecuador
- Volunteers
- 56 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Chronic Liver Disease
19Gauge Fine Needle Biopsy (FNB) Versus 22Gauge FNB for Endoscopic Ultrasound Guided Liver Biopsy (EUS-LB)
To determine the adequacy of EUS-LB using a 19G core needle compared to a 22G core needle in a prospective randomized study.
- Trial name
- NCT04806607
- Testing
- 19G FNB, 22G FNB
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Geisinger Clinic
Pancreatic Collection
Lumen Apposing Metal Stents With and Without a Double Pigtail Stent in Pancreatic Collections
The study evaluates the security of LAMS with ando without a coaxial double pigtail plastic stent in the management of pancreatic fuid collections.
- Trial name
- NCT03282539
- Testing
- LAMS, LAMS + pigtail
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- Hospital Universitari de Bellvitge
Malignant Hilar Stricture
ERCP With and Without EUS Guided HGS for Bilateral Biliary Decompression in Malignant Hilar Biliary Obstruction
A prospective randomized clinical trial to evaluate efficacy and safety of combined EUS-HGS and ERCP compared to ERCP for bilateral biliary decompression in advanced malignant hilar biliary obstruction.
- Trial name
- NCT06613945
- Testing
- ERCP biliary drainage, Combined ERCP and EUS-HGS biliary drainage
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Endoscopic Ultrasonography, Sedation
End-Tidal Carbon Dioxide Monitoring Device for Sedation During Endoscopic Ultrasonography
To meet the needs of both operators and patients, moderate and deep sedation has been widely used in digestive endoscopy, which is invasive and painful. With its pleasant effects, sedation has complications nevertheless.
- Conditions
- Endoscopic Ultrasonography, Sedation, Monitoring
- Trial name
- NCT04549623
- Testing
- Novel end-tidal CO2 monitoring device, SpO2 and respiratory motion monitoring
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Changhai Hospital
Chronic Liver Disease
Comparison and Outcomes of Endoscopic Ultrasound Liver Biopsies Versus Percutaneous Liver Biopsies
Histopathological examination of liver tissue is used to determine the etiology and extent of liver disease. In order for a clinician to make a better-informed decision regarding a patient with liver disease, the liver biopsy…
- Trial name
- NCT04751045
- Testing
- EUS liver biopsy
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Missouri-Columbia
Non Small Cell Lung Cancer
Study Comparing EBUS & EUS to Mediastinoscopy in Staging and Detection of Lung Cancer
This is a prospective randomized clinical trial with the study cohort comprised of all male and female patients over the age of 21 presenting to the study site for evaluation of lung cancer.
- Trial name
- NCT00970645
- Testing
- Mediastinoscopy/thoracoscopy, EBUS/EUS
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Pancreaticobiilary Diseases
Effect of Same-session EUS on ERCP in Pancreaticobiliary Diseases
This is a single-center randomized controlled trial. Eligible subjects meeting inclusion/exclusion criteria will be randomized 1:1 to EUS+ERCP group or ERCP group.
- Trial name
- EUS、 ERCP (NCT06978231)
- Testing
- EUS+ERCP, ERCP
- Where
- China
- Volunteers
- 214 people
- Sponsor
- Qilu Hospital of Shandong University
Portal Hypertension, Chronic Liver Disease
Within-Session Repeatability of EUS-Guided Portal Pressure Gradient Measurement
This prospective multicentre observational reliability study will determine how much a repeated endoscopic ultrasound-guided portal pressure gradient (EUS-PPG) measurement differs from the first measurement in the same patient…
- Conditions
- Portal Hypertension, Chronic Liver Disease, Liver Cirrhosis
- Trial name
- REPEAT-PPG (NCT07877298)
- Testing
- Repeated EUS-Guided Portal Pressure Gradient Measurement
- Where
- 5 sites in Belgium, Canada and 2 more
- Volunteers
- 150 people
- Sponsor
- University Hospital Muenster
Lung Cancer, Lymphoma
Improving Genomic Profiling and Reducing Time to Cancer Treatment Via Targeted Use of Endoscopic Ultrasound
Aim: To investigate whether the novel 3rd generation FNB needle provides a better diagnostic accuracy than a standard FNA needle in EUS-B guided diagnosis of common deep seated thoracic malignancies (lung cancer and lymphoma).
- Conditions
- Lung Cancer, Lymphoma, Sarcoidosis
- Trial name
- IMPROVED (NCT06848738)
- Testing
- FNB, FNA
- Where
- 3 sites in Denmark
- Volunteers
- 362 people
- Sponsor
- Zealand University Hospital
Mediastinal Disease
Validation of an AI-Assisted Mediastinal EUS System for Training Improvement: a Prospective, Multi-Center, Randomized Trial
The goal of this clinical trial is to verify the auxiliary role of the artificial intelligence (AI) system in mediastinal endoscopic ultrasound (EUS) scans. The main questions it aims to answer are as follows: 1.
- Trial name
- NCT06790108
- Testing
- Artificial intelligence device
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University
Competency-Based Education
Rapid Assessment of Trainee Endoscopy Skills (RATES) Study
The establishment of a number of training programs in therapeutic endoscopy, standardization of the performance of endoscopic ultrasound (EUS) and endoscopy retrograde cholangiopancreatography (ERCP) and definition of competence…
- Trial name
- RATES (NCT02247115)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Idiopathic Gastroparesis, Diabetic Gastroparesis
Intraluminal Endosonography for Examination of the Structural Changes of the Stomach in Gastroparetic Patients
Patients who empty their stomach slowly may have what we call "Slow gastric emptying" or "gastroparesis". These patients can have some changes in the thickness of their stomach wall.
- Trial name
- NCT01916460
- Testing
- Endoscopic Ultrasound Fine Needle Aspiration (EUS-FNA)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Pancreatic Diseases
The 22G Trident Needle Combined With Different Aspiration Techniques for Endoscopic Ultrasound-guided Fine-needle Biopsy
The goal of this clinical study is to compare the tissue adequacy, cellularity, blood contamination, accuracy, sensitivity, specificity of the 22G Trident needle combined with three different aspiration techniques (dry-suction…
- Trial name
- NCT07023562
- Testing
- ABC suction sequence, ACB suction sequence, BAC suction sequence
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Changhai Hospital
Neuroendocrine Tumors
Nonfunctioning Small (≤2 cm) Neuroendocrine Pancreatic Incidentaloma
Neuroendocrine tumors (NETs) and carcinomas account for 10-15 % of all pancreatic incidentalomas. The management of pancreatic NETs depends on tumor stage and on presence or not of hormonal syndrome.
- Trial name
- NCT03022188
- Where
- 22 sites in Belgium, France
- Volunteers
- 100 people
- Sponsor
- Société Française d'Endoscopie Digestive
Complication
Safety and Efficiency of Electrocautery-enhanced Lumen-apposing Stents - a Single Center Experience
Lumen approximating stents have been used in interventional endoscopy to treat retentions in the upper gastrointestinal tract for 10 years.
- Trial name
- NCT05210842
- Testing
- Endoscopy
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Salzburger Landeskliniken
Colorectal Endoscopic Submucosal Dissection(ESD) Surgery
Endoscopic Ultrasound Guided Colorectal ESD and Traditional Colorectal ESD Surgery
A prospective randomized controlled study protocol between endoscopic ultrasound guided colorectal ESD and traditional colorectal ESD surgery
- Trial name
- NCT06076382
- Testing
- endoscopic ultrasound guided colorectal ESD surgery, the traditional colorectal ESD surgery
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Jilin University
Pancreatic Cysts
Registry and Fluid Banking of Pancreatic Cystic Lesions
The purpose of this study is to follow patients, who have small mucinous cysts in the pancreas, prospectively over a 5-year period.
- Trial name
- NCT01769534
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma