Clinical trials: EUS
Pancreatic Cystic Lesion, Mucinous Cystadenoma of Pancreas
Management of Pancreatic Cystic Lesions Using Artificial Intelligence Based on EUS and Multimodal Data
The primary objective is to construct a multimodal AI model (Cyst-AI) based on EUS images and clinical data such as imaging features(CT or MRI) and laboratory tests to assist endoscopists in the diagnosis of pancreatic cystic…
- Conditions
- Pancreatic Cystic Lesion, Mucinous Cystadenoma of Pancreas, Intraductal Papillary Mucinous Neoplasm of Pancreas, Pseudocyst Pancreas
- Trial name
- NCT07463872
- Testing
- Cyst-AI model
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- Huazhong University of Science and Technology
Cirrhosis, Liver Disease Chronic
Inferior Vena Cava Pressure as Alternative to Hepatic Venous Pressure for EUS-guided Portal Pressure Gradient Measurement
This study investigates a new, simplified approach to measuring blood pressure within the liver (portal hypertension) using Endoscopic Ultrasound-Guided Portal Pressure Gradient Measurement (EUS-PPG).
- Conditions
- Cirrhosis, Liver Disease Chronic, Portal Hypertension
- Trial name
- EUS-VEIN (NCT07703540)
- Testing
- HVP-PPG and IVCP-PPG
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital Muenster
Childbirth Related Levator Injuries
Evaluation of Levator Injuries Using Transvaginal Endosonography
Prospective studies to date have identified that the levator ani muscle injuries occur in 14-19% of women after vaginal delivery. In none of studies a vaginal examination was performed at the time of delivery.
- Trial name
- ELITE (NCT01310660)
- Where
- United Kingdom
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Croydon University Hospital
Pancreatic Disease, Pancreatic Cancer
EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope
This is a randomized trial to compare the standard echoendoscope with the newly developed EndoSound Visual System in the evaluation of lesions in the gastrointestinal tract.
- Conditions
- Pancreatic Disease, Pancreatic Cancer, Pancreatic Cyst, Gastrointestinal Tumor
- Trial name
- NCT06340620
- Testing
- Endoscopic ultrasound examination
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Orlando Health, Inc.
Liver Cancer
A Prospective, Single-arm, Multicenter Clinical Trial of Safety and Effectiveness of EUS-LA for Liver Cancer
This trial is a prospective, single-arm, multi-center clinical trial. Four hospitals with national medical trial institution qualifications are selected as clinical trial centers.
- Trial name
- NCT05709886
- Testing
- EUS-LA by LaserPro Diode Laser System
- Where
- China
- Volunteers
- 69 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Hilar Cholangiocarcinoma, Duodenal Neoplasms
Diagnostic Accuracy of Eus Fnb in Difficult to Reach Lesions
The present study aims at comprehensively assessing the diagnostic performance and safety profile of EUS-FNB as a primary diagnostic tool for suspected malignancies in anatomically complex or deeply situated regions, including…
- Trial name
- NCT07621536
- Where
- Italy
- Volunteers
- 131 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Obesity
Effects of Gastric Antral Botulinum Toxin Injections in Obese Subjects
Obesity is an important public health problem in the United States. The investigators hypothesize that stomach injections of botulinum toxin A (BTA), delivered through an endoscope using endoscopic ultrasound (EUS), may cause…
- Trial name
- NCT00976443
- Testing
- BTA
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diagnosis of a Pancreaticobiliary Disorder, Biopsy
Comparison of FNB to EUS-CNB for Pancreatic Lesions
The primary aim of this study is to compare the tissue specimen quality and diagnostic accuracy of biopsies obtained with one puncture of a regular 22 FNB G needle and the motorized EUS CNB device of pancreatic lesions.
- Conditions
- Diagnosis of a Pancreaticobiliary Disorder, Biopsy, EUS Guided Biopsy
- Trial name
- NCT07240818
- Testing
- endoscopic ultrasound guided biopsy with core needle biopsy device, EUS-FNB
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Pancreatic Cyst
Clinical Evaluation of EUS-FNA on Diagnosis of Pancreatic Cystic Lesions
It is still controversial about the necessity of endoscopy ultrasound guide fine needle aspiration (EUS-FNA) on diagnosis of pancreatic cystic lesions(PCL).The aim of this study is to find the influence of EUS-FNA on diagnosis…
- Trial name
- NCT02041897
- Testing
- EUS-FNA
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Xiaoyin Zhang
Gall Stones, Gall Stones (& [Calculus - Gall Bladder])
A Study on the Efficacy and Safety of Endoscopic Ultrasound-guided Gastro-/Duodeno-cholecystostomy for the Treatment of Gallstones.
Gallstones, as a common benign gallbladder disease worldwide, have a prevalence of approximately 6.1%. Although laparoscopic cholecystectomy (LC) is currently the mainstream treatment, its associated complications cannot be…
- Trial name
- NCT07522385
- Testing
- cholecystolithotomy
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Ampullary Cancer, Duodenal Cancer
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders
Our institution performs therapeutic ERCP (Endoscopic retrograde cholangiopancreatography ), Endoscopic Ultrasound (EUS) and Interventional Endoscopy in around 1000 patients a year.
- Conditions
- Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer, Bile Duct Disorders
- Trial name
- NCT01438385
- Testing
- Interventional Endoscopy
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Weill Medical College of Cornell University
Cholecystitis
Prospective Evaluation of an Endoscopic Ultrasound (EUS)-Based Artificial Intelligence to Assist in the Deployment of Lumen Apposing Metal Stents for Gallbladder Drainage
Lumen apposing metal stents are now being used to help patients who suffer from cholecystitis (infection of the gallbladder), especially in cases where patients are not candidates for surgery.
- Trial name
- EUS-AI GBD (NCT06981052)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Pancreatic Neoplasm
Core Biopsy Endo Sonography Study Evaluation of the Significance of the Pro-core® Needle
The study is designed to evaluate the diagnostic accuracy of a new designed endoscopic ultrasonography (EUS) Core biopsy aspiration needle in comparison to a conventional EUS aspiration needle in GI-tumors.
- Trial name
- COS (NCT02181140)
- Testing
- EUS guided FNA and fine needle punction
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Walled-off Necrosis
A Comparison Between Lumen-apposing Metal Stent and Double-pigtail Plastic Stents for Treatment of Walled-off Necrosis
Walled-off necrosis (WON) is defined as an encapsulated collection of solid and liquid necrotic material that is usually formed 4 weeks after an episode of acute necrotizing pancreatitis.
- Trial name
- NCT04876235
- Testing
- endoscopic ultrasound, lumen-apposing metal stent, double-pigtail plastic stents
- Where
- China
- Volunteers
- 50 people
- Sponsor
- First People's Hospital of Hangzhou
Lung Cancer, Lymphoma
Improving Genomic Profiling and Reducing Time to Cancer Treatment Via Targeted Use of Endoscopic Ultrasound
Aim: To investigate whether the novel 3rd generation FNB needle provides a better diagnostic accuracy than a standard FNA needle in EUS-B guided diagnosis of common deep seated thoracic malignancies (lung cancer and lymphoma).
- Conditions
- Lung Cancer, Lymphoma, Sarcoidosis
- Trial name
- IMPROVED (NCT06848738)
- Testing
- FNB, FNA
- Where
- 3 sites in Denmark
- Volunteers
- 362 people
- Sponsor
- Zealand University Hospital
Throat Pain After EUS Insertion
A Comparison of Endoscopic Ultrasound Insertion Methods
Endoscopic ultrasonography (EUS) is an essential technique required in diagnosis of pancreatobiliary diseases. In previous studies, 6% of patients who undergone EUS had significant throat pain.
- Trial name
- NCT02924948
- Testing
- Balloon inflation
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Treatment Related Cancer
Pancreatic Cyst Ablation With a Monopolar Radiofrequency Ablation Probe
Pancreatic cysts (A cyst is a thin walled cavity containing fluid) were rarely reported previously, but have been on a rise due to advanced imaging for evaluating pancreatic lesions or other medical reasons has increased…
- Trial name
- NCT04253249
- Where
- United States
- Sponsor
- Baylor College of Medicine
Cirrhosis, Compensated Cirrhosis
The Use of Endoscopic Ultrasound-Guided Portal Pressure Measurements to Guide Beta-Blocker Therapy in Patients With Compensated Cirrhosis
This pilot study to determine the feasibility of EUS-Portal Pressure Measurements to guide Beta-Blocker Therapy in patients with compensated cirrhosis .The study will be a prospective tandem controlled trial consisting of 30…
- Conditions
- Cirrhosis, Compensated Cirrhosis, Portal Hypertension
- Trial name
- NCT05357599
- Testing
- EUS
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Pancreatic Solid Lesions
Different Suction Techniques For Endoscopic Ultrasound-Guided Fine-Needle Biopsy In Pancreatic Solid Lesions
Ultrasound-guided fine-needle aspiration represents the gold-standard for the pathological diagnosis of solid pancreatic lesions.
- Trial name
- NCT03849209
- Testing
- Stylet slow-pull technique, Standard suction technique
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- ARNAS Civico Di Cristina Benfratelli Hospital
Competency-Based Education
Rapid Assessment of Trainee Endoscopy Skills (RATES) Study
The establishment of a number of training programs in therapeutic endoscopy, standardization of the performance of endoscopic ultrasound (EUS) and endoscopy retrograde cholangiopancreatography (ERCP) and definition of competence…
- Trial name
- RATES (NCT02247115)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver