Clinical trials: EUS
Solid Pancreatic Neoplasms, Endoscopic Ultrasound
Non-hypovascular Solid Pancreatic Lesions: Role of EUS
Vascular pattern of solid pancreatic lesions (SPLs) has been investigated by different abdominal imaging modalities and by contrast-enhanced endoscopic ultrasonography (CE-EUS).
- Trial name
- LE-VASC (NCT03738280)
- Testing
- Endoscopic ultrasound-fine needle biopsy
- Where
- Italy
- Volunteers
- 154 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Pancreas Cancer
Pancreatic Cancer Molecular Sub-classification Using Endoscopic Ultrasound Tissue Core Biopsy Samples
This study evaluated the feasibility and reliability of PDAC molecular subtyping on tissue core biopsies samples acquired under EUS guidance.
- Trial name
- NCT04246710
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Catholic University of the Sacred Heart
Endoscopic Ultrasonography-guided Fine Needle Aspiration
EUS-FNA for Patients Taking Anticoagulants Without Heparin Bridge
To evaluate the feasibility of EUS-FNA for patients taking anticoagulants without heparin bridge.
- Trial name
- NCT02977650
- Testing
- Endoscopic ultrasonography-guided fine needle aspiration
- Where
- Japan
- Volunteers
- 150 people
- Sponsor
- Hokkaido Pancreatobiliary Endoscopic Intervention Study Group
Pancreatic Diseases, Bile Duct Diseases
Patient Reported Experience in Endoscopic Ultrasound
The evaluation of the patient's experience is becoming increasingly important as a better patient experience can improve the quality of the delivered health service.
- Trial name
- PREUS (NCT05014347)
- Where
- Italy
- Volunteers
- 171 people
- Sponsor
- IRCCS San Raffaele
Inoperable Disease, Bile Duct Cancer
CH-EUS in Diagnosis of Inoperable Bile Duct Tumors
VALIDATION OF THE SUPERIORITY OF CONTRAST ENHANCED ENDOSCOPY TO STANDARD ENDOSCOPY IN THE DIAGNOSIS OF BILE DUCT TUMORS
- Trial name
- NCT05418543
- Testing
- Endoscopic ultrasound with fine needle biopsy
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian Fodor
Diagnoses Diseases, Ultrasound Therapy; Complications
19 Versus 22-Gauge Needle for EUS-LB
Chronic liver disorders (CLD) are a major cause of morbidity and mortality for individuals in the US. Though serologic analysis will often lead to a conclusive diagnosis, liver biopsy remains an important method for helping to…
- Conditions
- Diagnoses Diseases, Ultrasound Therapy; Complications, Liver Diseases
- Trial name
- EUSLB1922 (NCT02967991)
- Testing
- EUS-guided liver biopsy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Autoimmune Pancreatitis
EUS-guided Procore-biopsy in Diagnosing Autoimmune Pancreatitis
The goal of this prospective study is to evaluate the feasibility of the Core Biopsy Needle with reverse bevel (Procore TM) in diagnosing autoimmune pancretitis
- Trial name
- NCT01774513
- Testing
- Procore-Needle
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Technical University of Munich
Hypoglycemia, Gastric Outlet Obstruction
Endoscopic Ultrasound-guided Large Diameter Lumen-apposing Metal Stent Gastro-gastrostomy for Bypass Reversal in Patients With Roux-en-y Gastric Bypass
The primary objective of this open-label pilot study is to investigate whether an endoscopically placed lumen apposing metal stent is an effective alternative to surgery in patients that have a clear indication for reversal of…
- Conditions
- Hypoglycemia, Gastric Outlet Obstruction, Steatohepatitis, Parenteral Support
- Trial name
- LABOR (NCT05640947)
- Testing
- The Hot AXIOS™ Stent and Electrocautery-Enhanced Delivery System
- Where
- 2 sites in Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Ghent
Pancreatic Cystadenoma
EUS-Guided Pancreatic Injection of Cyst (EPIC) Trial
The purpose of the study is to learn about a new treatment for pancreatic cystic lesions. The injection of alcohol into cysts is a common way of treating cysts of the liver, kidney, and thyroid.
- Trial name
- NCT00233038
- Testing
- Ethanol injection into a cyst
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Acute Pancreatitis, Peripancreatic Fluid Collections
Early Versus Standard Endoscopic Interventions for Peripancreatic Fluid Collections
Acute pancreatitis is a complex gastrointestinal disease with a variable course that is often difficult to predict early in its development. The majority of cases are mild, self-limited, and follow an uncomplicated course.
- Conditions
- Acute Pancreatitis, Peripancreatic Fluid Collections, Endoscopic Ultrasound-Guided Drainage, Pancreatic Fluid Collections
- Trial name
- NCT05281458
- Testing
- Early drainage of peripancreatic fluid collections
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Cirrhosis, Portal Hypertension
The Feasibility, Safety, and Efficacy of EUS-Guided PSE: A Cohort Study
Bleeding from esophagogastric varices in patients with liver cirrhosis is often life-threatening. Thrombocytopenia caused by hypersplenism secondary to portal hypertension is an independent risk factor for such gastrointestinal…
- Conditions
- Cirrhosis, Portal Hypertension, Bleeding
- Trial name
- EUS; PSE (NCT07354789)
- Testing
- EUS guided PSE
- Volunteers
- 50 people
- Sponsor
- Qilu Hospital of Shandong University
Esophagogastric Varices
EUS-PPG Alteration After Ligation and Sclerotherapy in Esophageal Varices
Acute variceal bleeding due to cirrhotic portal hypertension is a life-threatening emergency in gastroenterology. Current preventive strategies include non-selective β-blockers (e.g., carvedilol/propranolol), endoscopic therapy…
- Trial name
- NCT07253090
- Testing
- Sclerotherapy for esophageal varices, Ligation for esophageal varices
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Calculous Cholecystitis
GALLVIA Trial: EUS-Guided vs Transpapillary Gallbladder Drainage for Acute Calculous Cholecystitis
This multicenter, prospective, open-label, randomized controlled trial compares endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) with endoscopic transpapillary gallbladder drainage (EGBS) in poor surgical candidates…
- Trial name
- GALLVIA (NCT07536191)
- Testing
- Endoscopic Ultrasound-Guided Gallbladder Drainage, Endoscopic Transpapillary Gallbladder Drainage
- Where
- 5 sites in Japan
- Volunteers
- 90 people
- Sponsor
- Aichi Medical University
Pancreatic Solid Lesions
The Comparison of Wet Suction and Dry Suction Technique in EUS-FNA for the Outcomes in Pancreatic Solid Lesions
The objective of this randomized controlled trial is to evaluate whether wet suction technique (WST), compared with dry suction technique (DST), shall present a better outcome with regard to the diagnostic yield and specimen…
- Trial name
- NCT03821974
- Testing
- wet suction technique, dry suction technique
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Jaundice
Biliary Drainage in Patients With Duodenal Metal Stent
This is a retrospective study to evaluate the outcomes of endoscopic biliary drainage according to the timing of distal malignant biliary obstruction (MBO) in relation to gastric outlet obstruction (GOO) and the location of GOO.
- Trial name
- NCT02376907
- Testing
- Biliary drainage
- Where
- 25 sites in China, Hong Kong and 7 more
- Volunteers
- 200 people
- Sponsor
- Tokyo University
Crohn Disease, Rectal Fistula
Endoscopic Ultrasound (EUS) Guided Treatment With Humira for Crohn's Perianal Fistulas
This study is to assess whether utilizing endoscopic ultrasound(EUS) to guide treatment can improve durable fistula healing in patients with Crohn's perianal fistulas and to get preliminary information regarding the effectiveness…
- Trial name
- NCT00517296
- Testing
- EUA with seton placement if necessary, adalimumab, EUS
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Vanderbilt University Medical Center
Neuroendocrine Tumors
Nonfunctioning Small (≤2 cm) Neuroendocrine Pancreatic Incidentaloma
Neuroendocrine tumors (NETs) and carcinomas account for 10-15 % of all pancreatic incidentalomas. The management of pancreatic NETs depends on tumor stage and on presence or not of hormonal syndrome.
- Trial name
- NCT03022188
- Where
- 22 sites in Belgium, France
- Volunteers
- 100 people
- Sponsor
- Société Française d'Endoscopie Digestive
Pancreatic Cancer, Pancreatic Neoplasms
Evaluation of Safety and Feasibility of EUS-guided RFA for Solid Pancreatic Neoplasms
This study aims to evaluate the safety and efficacy of new ablation catheter developed by MEDICAL TAEWOONG for the treatment of pancreatic neoplasm (pancreatic adenocarcinoma or neuroendocrine tumour).
- Conditions
- Pancreatic Cancer, Pancreatic Neoplasms, Pancreatic Adenocarcinoma, Pancreatic Neuroendocrine Tumor
- Trial name
- NCT03435770
- Testing
- EUSRA RFA needle
- Where
- Singapore
- Volunteers
- 10 people
- Sponsor
- Singapore General Hospital
Esophageal Subepithelial Lesions
EUS-CNB Versus EUS-SINK for Diagnosis of Upper Gastrointestinal (UGI) Subepithelial Tumors
This is a single-blinded randomized control trial trying to compare the effectiveness of diagnosis between two techniques employed in tissue sampling for subepithelial tumors (SETs) of the gastrointestinal tract.
- Trial name
- NCT02282111
- Testing
- 22-gauge Procore needle (ProCore, Cook Medical Inc., Winston-Salem, NC), conventional needle-knife sphincterotome (Microknife XL; Boston Scientific Inc, Natick, Mass)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Johns Hopkins University
Gastric Outlet Obstruction
EUS-GE vs ES for Palliation of Gastric Outlet Obstruction
Gastric outlet obstruction (GOO) is a common complication of luminal malignancies which is associated with substantial morbidity.
- Trial name
- NCT03259763
- Testing
- Lumen-apposing metal stent, Self-expandable metal stent
- Where
- 9 sites in United States, Canada and 5 more
- Volunteers
- 112 people
- Sponsor
- Johns Hopkins University