Clinical trials: EUS
Liver Cirrhosis
Comparison of Pre-operative EUS Guided and Intra-operative Direct Portal Vein Pressure Measurement in Pretransplant Cirrhotics
Direct portal pressure measurement under EUS-guidance (EUS-PPM) is a promising alternative to conventional indirect Hepatic Venous Pressure Gradient (HVPG).
- Trial name
- NCT06114355
- Testing
- EUS Portal pressure measurement
- Volunteers
- 25 people
- Sponsor
- Asian Institute of Gastroenterology, India
Cancer of Pancreas, Pancreatic Neoplasms
EUS-Coeliac Plexus Block Versus Radiofrequency Ablation in Pain Relief of Patients With Malignancy
Many cancer patients suffer from intractable pain and which is often suboptimally controlled by even strong opioid analgesics. Coeliac plexus neurolysis (CPN) is procedure which intended to permanently destroy the nociceptive…
- Conditions
- Cancer of Pancreas, Pancreatic Neoplasms, Pain, Cancer-Associated Pain
- Trial name
- NCT04809935
- Testing
- 98% dehydrated alcohol, 19G EUSRA needle, Taewoong Medical, Korea
- Where
- Hong Kong
- Volunteers
- 54 people
- Sponsor
- The University of Hong Kong
Common Bile Duct Calculi
The Cost Effectiveness of Endoscopic Ultrasound ( EUS ) Based Strategy in Diagnosis of Common Bile Duct Stones
Multiple reports in the literature showed the efficacy of EUS comparable to ERCP in the diagnosis of common bile duct ( CBD ) stone.
- Trial name
- NCT02349568
- Testing
- High risk group, Intermediate risk group
- Where
- Thailand
- Volunteers
- 141 people
- Sponsor
- Prince of Songkla University
Pancreatic Neoplasms
Discovery of Soluble Biomarkers for Pancreatic Cancer Using Innovative All-Patient Inclusive Methodology
Pancreatic ductal adenocarcinoma (PDAC) remains among cancers with a very poor prognosis (1-year survival <20%). Endoscopic ultrasound with fine needle aspiration (EUS/FNA) is the common examination for all patients with…
- Trial name
- PanEXPEL2 (NCT04370574)
- Testing
- Soluble Biomarkers dosage
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Gastrointestinal Stromal Tumor of Stomach, Submucosal Tumor of Stomach
MCB vs EUS-FNA for Preoperative Pathological Evaluation of Gastric SMT
Gastrointestinal stromal tumors (GISTs) are the most common submucosal tumors (SMTs) of the stomach. The 2022 European Society of Oncology ESMO Diagnosis and Treatment Guidelines recommend that GISTs undergo biopsy with a clear…
- Trial name
- NCT06748690
- Testing
- mucosal cutting biopsy, endoscopic ultrasound-guided-fine needle aspiration
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Peking University People's Hospital
Acute Cholecystitis
EUS-GBD vs Antibiotics for Patients at High Risk for Cholecystectomy
Objectives Acute cholecystitis commonly occurs in elderly patients who are at high-risk for surgery. Whether upfront Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) is advantageous over antibiotics first for mild…
- Trial name
- NCT05893511
- Testing
- Endoscopic ultrasound-guided gallbladder drainage, Antibiotics first
- Where
- Hong Kong
- Volunteers
- 110 people
- Sponsor
- Chinese University of Hong Kong
Solid Pancreatic Tumor
Endoscopic Ultrasound (EUS)-Guided Fine Needle Aspiration (FNA) With Rapid On-site Evaluation (ROSE) of Cytopathology vs. EUS-guided Fine Needle Biopsy (FNB) Alone in the Diagnosis of Pancreatic Solid Lesions
Currently, the best way to evaluate pancreatic masses is through endoscopic-guided needle sampling of the mass to determine the diagnosis by looking at the acquired tissue under a microscope.
- Trial name
- NCT03435588
- Testing
- EUS, FNA with ROSE, FNB alone
- Where
- 6 sites in Canada
- Volunteers
- 235 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
The Malignant Lesions and Non-malignant Lesions of Pancreas, Bile Duct, Liver and Lymph Node
An Artificial Intelligence System for ROSE of EUS-FNA Sample: a Prospective, Multicenter, Diagnostic Study.
This is an observational study with a prospective, multicenter, disgnostic design. An artificial intelligence system named ROSE-AI system was developed using cytopathological slide images taken by microscope camera or smartphone…
- Trial name
- ROSE，EUS-FNA (NCT06718725)
- Testing
- ROSE-AI system
- Where
- China
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Cholecystitis
Prospective Trial for Endoscopic Ultrasound Guided Gallbladder Drainage for Acute Cholecystitis in High Risk Patients
The investigators would like to conduct a prospective, randomized non-inferiority study to compare clinical outcome between endoscopic ultrasound (EUS) guided gallbladder drainage and percutaneous transhepatic gallbladder…
- Trial name
- NCT01146743
- Testing
- EUS-guided gallbladder drainage, percutaneous transhepatic gallbladder drainage
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Asan Medical Center
Therapeutic Endoscopic Ultrasound, Advanced Endoscopy
Therapeutic Endoscopic Ultrasound for Gastrointestinal Disorders: A Multicenter Registry Study
The purpose of this retrospective chart-review registry study is to evaluate the safety profile, efficacy profile and cost-effectiveness of the various therapeutic endoscopic ultrasound (EUS) procedures (for benign and malignant…
- Conditions
- Therapeutic Endoscopic Ultrasound, Advanced Endoscopy, Therapeutic Endoscopy, Interventional Endoscopy
- Trial name
- TEUS Registry (NCT05051358)
- Testing
- Therapeutic Endoscopic Ultrasound
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Advanced Endoscopy Research, Robert Wood Johnson Medical School Rutgers University
Pancreatic Cancer, Pancreatic Neuroendocrine Tumor
Safety and Efficacy of an Ablation Catheter for the Treatment of Pancreatic Premalignant Cyctic Lesions.
This study aims to evaluate the safety and efficacy of new ablation catheter developed by MEDICAL TAEWOONG for the treatment of pancreatic premalignant and early malignant cystic lesion.
- Conditions
- Pancreatic Cancer, Pancreatic Neuroendocrine Tumor, Pancreatic Cyst, Pancreatic Cancer Stage
- Trial name
- yes (NCT03417843)
- Testing
- EUSRA RF electrode
- Volunteers
- 20 people
- Sponsor
- HaEmek Medical Center, Israel
Diagnosis of a Pancreaticobiliary Disorder, Biopsy
Comparison of FNB to EUS-CNB for Pancreatic Lesions
The primary aim of this study is to compare the tissue specimen quality and diagnostic accuracy of biopsies obtained with one puncture of a regular 22 FNB G needle and the motorized EUS CNB device of pancreatic lesions.
- Conditions
- Diagnosis of a Pancreaticobiliary Disorder, Biopsy, EUS Guided Biopsy
- Trial name
- NCT07240818
- Testing
- endoscopic ultrasound guided biopsy with core needle biopsy device, EUS-FNB
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Pancreatic Pseudocyst
Efficacy and Safety of HANAROSTEN® HOT Plumber™ With Z-EUSIT™ for Pancreatic Pseudocyst Drainage
The goal of this prospective, single-center observational study is to evaluate the safety and effectiveness of the HANAROSTEN® HOT Plumber™ with Z-EUSIT™ for draining pancreatic pseudocysts.
- Trial name
- ZEUS (NCT06855485)
- Testing
- HANAROSTEN® HOT Plumber™ with Z-EUSIT™
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Asan Medical Center
Pancreatic Cancer, Lymphadenopathy
Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy Needle
Endoscopic ultrasound (EUS) is paramount in the diagnosis and evaluation of cancers involving the gastrointestinal tract. EUS allows for the acquisition of cellular (fine needle aspirate - FNA) or tissue biopsy (fine needle…
- Conditions
- Pancreatic Cancer, Lymphadenopathy, Gastrointestinal Stromal Tumor
- Trial name
- MUCIN (NCT01769248)
- Testing
- Fine needle aspiration, Fine needle biopsy
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- Northwestern University
CTCs, Pancreatic Cancer
EUS-guided CTCs + Multi-omics: Predicting Pancreatic Cancer Recurrence and Metastases
The investigators conduct a single-center, prospective, observational study to explore the value of EUS-guided portal vein circulating tumor cells (PV-CTCs) and their subtypes combined with multi-omics tests in the early warning…
- Conditions
- CTCs, Pancreatic Cancer, Liver Metastases, Relapse
- Trial name
- NCT07448376
- Testing
- CTC
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Huazhong University of Science and Technology
Pancreatic Masses
The Use of a New Core Needle in the Endoscopic Ultrasound Assisted Tissue Sampling for Pancreatic Solid Masses
Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA) is a reliable, safe, and effective technique for obtaining samples from pancreatic masses.
- Trial name
- NCT02946840
- Testing
- FNA with 25 G Beacon needle
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Clinico Humanitas
Pancreatic Neoplasm
Comparing Biopsy Needles for Endoscopic Ultrasound Guided Samples for Pancreatic Masses
This is a randomized prospective clinical study comparing a fine needle biopsy device and an aspiration needle.
- Trial name
- Expect (NCT02911974)
- Testing
- Acquire EUS Biopsy Device, Expect EUS Aspiration Needle
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- AdventHealth
Colorectal Subepithelial Lesions
Diagnostic Accuracy of EUS for Colorectal Submucosal Masses
This study aims to evaluate the diagnostic accuracy of endoscopic ultrasound (EUS) for colorectal submucosal tumors/lesions (SMTs/SELs) and to identify factors associated with correct EUS diagnosis.
- Trial name
- NCT07351890
- Testing
- Endoscopic Ultrasound (EUS) Assessment
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Run-hua Li
Pancreatic Fistula
Ultrasound Elastography for Prediction of Postoperative Pancreatic Fistula
The purpose of this study is to assess the value of preoperative objective modalities such as endoscopic ultrasound elastography and magnet resonance imaging in predicting development of postoperative pancreatic fistula in…
- Trial name
- PMPPOPF (NCT02589379)
- Testing
- Pancreatic Resection
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- University of Zurich
Treatment Related Cancer
Pancreatic Cyst Ablation With a Monopolar Radiofrequency Ablation Probe
Pancreatic cysts (A cyst is a thin walled cavity containing fluid) were rarely reported previously, but have been on a rise due to advanced imaging for evaluating pancreatic lesions or other medical reasons has increased…
- Trial name
- NCT04253249
- Where
- United States
- Sponsor
- Baylor College of Medicine