Clinical trials: EUS
Alcoholic Cirrhosis
EUS Based Prevalence of Chronic Pancreatitis in Alcoholic Cirrhosis
Alcohol is the common precipitating factor for both cirrhosis of liver as well as alcohol related chronic pancreatitis. However, in real life clinical setting, clinicians do not frequently see many cases of symptomatic…
- Trial name
- NCT04245189
- Testing
- Endoscopic ultrasound for detection of Chronic pancreatitis
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Asian Institute of Gastroenterology, India
Metastatic Pancreatic Cancer
Implantation of iodine125-Seeds Combined With Chemotherapy in the Treatment of Metastatic Pancreatic Carcinoma
The goal of this clinical trial is to evaluate the clinical efficacy and safety of endoscopic ultrasonography (EUS)-guided radioactive iodine 125 seeds in combination with AG regimen chemotherapy for the treatment of metastatic…
- Trial name
- NCT05869474
- Testing
- Iodine125-Seeds implantation, Gem/nab-P Chemotherapy
- Where
- China
- Volunteers
- 206 people
- Sponsor
- Changhai Hospital
Diagnoses Diseases, Ultrasound Therapy; Complications
19 Versus 22-Gauge Needle for EUS-LB
Chronic liver disorders (CLD) are a major cause of morbidity and mortality for individuals in the US. Though serologic analysis will often lead to a conclusive diagnosis, liver biopsy remains an important method for helping to…
- Conditions
- Diagnoses Diseases, Ultrasound Therapy; Complications, Liver Diseases
- Trial name
- EUSLB1922 (NCT02967991)
- Testing
- EUS-guided liver biopsy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Gastroesophageal Varices, Hypersplenism
EUS-guided PSE in Combination With EUS-guided Treatment of Varices for Patients With Portal Hypertension
This study aims to evaluate the efficiency of EUS-guided combination therapy (EUS-guided PSE + EUS-guided treatment of varices) to EUS-guided treatment of varices alone in cirrhotic patients with portal hypertension who have…
- Conditions
- Gastroesophageal Varices, Hypersplenism, Portal Hypertension
- Trial name
- NCT04692805
- Testing
- coils, cyanoacrylate glue
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Tongji Hospital
Gastric Outlet Obstruction
Novel Balloon-Assisted vs Direct Technique in EUS-Guided Gastroenterostomy
Gastric outlet obstruction (GOO) refers to mechanical blockage at the pylorus or duodenum, most commonly caused by unresectable malignancies of the stomach, duodenum, or pancreas.
- Trial name
- NCT07161856
- Testing
- a novel balloon-assisted EUS-GE, direct EUS-GE
- Volunteers
- 272 people
- Sponsor
- Changhai Hospital
Autoimmune Pancreatitis, Pancreatic Cancer
To Differentiate Focal Autoimmune Pancreatitis From Pancreatic Cancer by Endoscopic Ultrasound
Autoimmune pancreatitis (AIP) is a special type of chronic pancreatitis mediated by autoimmunity. The classic manifestation of AIP is diffuse pancreatic enlargement, some of which are characterized by focal enlargement.
- Trial name
- NCT04834505
- Testing
- Diagnostic imaging modalities for validation sample, EUS for derivation sample
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Peking Union Medical College Hospital
Abdominal Neoplasms
22 Gauge Needle for EUS Guided Tissue Acquisition of Samples for Histologic Examination
To determine the yield of tissue biopsy specimen and the diagnostic accuracy of tissue acquisition using a newly developed 22 gauge needle in patients with solid lesions throughout the GI tract.
- Trial name
- EUSFNTA (NCT04032951)
- Testing
- Fine Needle Tissue Acquisition
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Catholic University of the Sacred Heart
Gastric Outlet Obstruction, Biliary Obstruction
Prospective Registry Of Therapeutic EndoscopiC ulTrasound
This registry aims to analyze long-term outcomes of therapeutic EUS (T-EUS) procedures, as well as to describe clinical and technical variables potentially predicting clinical success or adverse events, for a better selection of…
- Conditions
- Gastric Outlet Obstruction, Biliary Obstruction, Acute Pancreatic Fluid Collection, Acute Pancreatitis With Infected Necrosis
- Trial name
- PROTECT (NCT04813055)
- Testing
- Therapeutic EUS, Percutaneous Procedures, Surgical Interventions
- Where
- Italy
- Volunteers
- 510 people
- Sponsor
- Paolo Giorgio Arcidiacono, MD
HIV, Hepatitis E
Seroprevalence of Hepatitis E in HIV Positive Patients in Basque Country in 2016 (VIhVhEpb)
Study of seroprevalence of hepatitis E among HIV positive patient in Basque country, France in 2016.
- Trial name
- VIhVhEpb (NCT02847507)
- Where
- France
- Volunteers
- 307 people
- Sponsor
- Centre Hospitalier de la côte Basque
Liver Metastases, Pancreatic Neoplasms
Role of EUS in Detection of Liver Metastasis
Liver metastasis may not be detected by CT and MRI due to their small size while they can be detected by EUS. Also, EUS-FNA has a great impact in improving the diagnostic accuracy of EUS.
- Trial name
- NCT04509492
- Testing
- Endoscopic ultrasound ( EUS )
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Mahmoud Wahba
Gastric Varices Bleeding, Endoscopic Ultrasound
Primary Prevention of Gastric Varices Bleed
Primary prophylaxis of gastric varices is an important area of research, as gastric varices are a common complication of cirrhosis of the liver.
- Trial name
- NCT05859009
- Testing
- EUS-Guided Therapy of Glue and Coil, Non-Selective Beta Blockers (Propanolol)
- Sponsor
- Unity Health Toronto
Obstructive Jaundice, Bilio-pancreatic Tumor
Endoscopic Ultrasound Evaluation of the Common Bile Duct in Patients With Obstructive Jaundice Due to Bilio-pancreatic Malignancies (ECCO Trial)
To assess the size of the common bile duct in a large cohort of patients with jaundice following a malignant tumor of the head of the pancreas or the distal bile duct receiving a diagnostic EA for biopsy and / or for evaluation…
- Trial name
- ECCO (NCT05155475)
- Testing
- Ultrasound endoscopy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Pancreatic Cancer, Pancreatic Adenocarcinoma
EUS-guided PORtal Vein Sampling for Circulating Tumor Cells in Pancreatic Cancer Patients
The study aims at evaluating the feasibility and safety of EUS-guided Portal Circulation sampling for isolation, enumeration and profiling od Circulating Tumor Cells (CTC) in Pancreatic Cancer patients.
- Trial name
- EUPhORIC (NCT05247164)
- Testing
- EUS-guided Portal Vein sampling
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- IRCCS San Raffaele
Walled Off Necrosis
To Evaluate Early (2-Week) vs. Standard (4-Week) Metal Stent Removal Following Endoscopic Ultrasound Guided WON Drainage
In adults with walled-off pancreatic necrosis (WON) undergoing endoscopic ultrasound (EUS)-guided transluminal necrosectomy, does early removal of the lumen-apposing metal stent (LAMS) (at 2 weeks or immediately after the last…
- Trial name
- STEP1 (NCT07307248)
- Testing
- Standard LAMS Removal with Double-Pigtail Plastic Stent, Standard LAMS Removal without DPT
- Where
- India
- Volunteers
- 408 people
- Sponsor
- Asian Institute of Gastroenterology, India
Cholecystolithiasis, Cholecystitis, Chronic
Elective Endoscopic Gallbladder Treatment: Pilot Study
Laparoscopic cholecystectomy (LC) represents the gold standard for treatment of elective and acute of gallbladder diseases, such as acute cholecystitis (AC).
- Trial name
- SLATAN (NCT05723224)
- Testing
- elective endoscopic gallbladder treatment
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Bile Duct Diseases
The Role of Endoscopic Ultrasound in Evaluation of Patients With Indefinite Cause of Bile Duct Dilatation
In the era of diagnostic imaging advances, Bile Duct Dilatation becomes a common incidental finding in patients present with either gastrointestinal symptoms or undergone the imaging study for any other complaints.
- Trial name
- NCT05475964
- Testing
- Endoscopic ultrasound
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- HMHamed
Post-surgical Intra-abdominal Collection
Retrospective Study of Endoscopic Ultrasound (EUS) Guided Transmural Drainage of Post-operative Abdominal Collections
This is a retrospective study of a single center on endoscopic ultrasound (EUS) guided transmural drainage of post-operative collections during a 9 years period.
- Trial name
- NCT01537848
- Testing
- EUS guided transmural drainage
- Where
- Belgium
- Volunteers
- 43 people
- Sponsor
- Erasme University Hospital
Cancer of Pancreas, Cancer of Stomach
Wet Heparinized Suction for Abdominal Cancer
The purpose of this research is to compare the amount and quality of tissue obtained by EUS-FNB when the device is flushed with an anticoagulant or "blood thinner" vs.
- Conditions
- Cancer of Pancreas, Cancer of Stomach, Cancer of Esophagus, Cancer of Liver
- Trial name
- EUS Heparin (NCT05041335)
- Testing
- wet heparinzed suction, Microsieve, No heparin flush
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Endoscopic Retrograde Cholangiopancreatography, Biliary Drainage
EUS-guided Biliary Drainage of First Intent With the Lumen Apposing Metal Stent vs. ERCP in the Management of Malignant Distal Biliary Obstruction (AXIOS-CPRE)
The main objective is to compare the EUS-BD with the insertion of a LAMS vs. traditional ERCP to restore biliary patency. Although ERCP has been the primary treatment for many years, it is associated with a significant risk of…
- Conditions
- Endoscopic Retrograde Cholangiopancreatography, Biliary Drainage, Echography Ultrasound
- Trial name
- AXIOS-CPRE (NCT05122858)
- Testing
- EUS guided biliary drainage, ERCP
- Where
- France
- Volunteers
- 15 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Pancreatic Masses, Lymph Nodes
Comparing a 25G EUS Fine Needle Aspiration (FNA) Device With a 20G EUS
The aim of this study is to compare the diagnostic accuracy of two EUS-guided tissue acquisition devices; the 25G Echotip Ultra Fine Needle Aspiration (FNA) device and the 20G Echotip ProCore Fine Needle Biopsy (FNB) device.
- Trial name
- ASPRO (NCT02167074)
- Testing
- 25G FNA needle, 20G ProCore FNB needle
- Where
- 13 sites in United States, Australia and 8 more
- Volunteers
- 615 people
- Sponsor
- Foundation for Liver Research