Clinical trials: EUS
Pancreatic Neoplasm
Comparison of Two Fine Needle Biopsy Needles for Solid Pancreatic Masses
This is a randomized prospective clinical study comparing the Acquire Biopsy Device to SharkCore Biopsy Device.
- Trial name
- Expect (NCT02910960)
- Testing
- Acquire EUS Biopsy Device, SharkCore Biopsy System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- AdventHealth
Gastrointestinal Neoplasms
Endoscopic Ultrasound in Detailed T-staging of Upper GI Malignancies in Vitro
In our era of personalized treatment, both the prognosis and the choice of therapy for upper GI malignancies depend on the staging before any treatment.
- Trial name
- NCT02226224
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Cancer Hospital & Institute
Autoimmune Pancreatitis
Evaluation of EUS-guided FNA for Diagnosing Autoimmune Pancreatitis
The aim is to evaluate EUS-FNA efficacy for AIP diagnosis using a 22-gauge (G) needle.
- Trial name
- NCT03241797
- Testing
- EUS-FNA
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Bin Cheng
Pancreas Cancer
Perfusion Assessment With Contrast-Enhanced EUS in Locally Advanced and Metastatic Pancreatic Cancer
Patients with non-resectable pancreatic cancer have a poor prognosis.The analysis of prognostic factors before treatment may be helpful in selecting appropriate candidates for chemotherapy and determining treatment strategies.
- Trial name
- PEACE (NCT03513198)
- Testing
- Endoscopic ultrasound (including fine needle aspiration), Contrast-enhanced endoscopic ultrasound (CE-EUS), Endoscopic ultrasound elastography (EG-EUS)
- Volunteers
- 200 people
- Sponsor
- University of Medicine and Pharmacy Craiova
Pancreas Cancer, Pancreas Neoplasm, Benign
Endoscopic Ultrasound Guided Tissue Sampling (The SharkBITE Study)
This study compares the diagnostic performance of Endoscopic ultrasound (EUS) guided fine needle aspiration and EUS guided core biopsy (SharkCore) in patients with a solid pancreatic mass.
- Conditions
- Pancreas Cancer, Pancreas Neoplasm, Benign, Chronic Pancreatitis, Pancreas Adenocarcinoma
- Trial name
- SharkBITE (NCT03532347)
- Testing
- EUS-FNA needle (Beacon)
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Gastric Varices Bleeding
Impact of EUS Guided Treatment of Gastric Varices
The purpose of the study is to determine the clinical impact of cyanoacrylate tissue adhesive treatment for Gastric Varices performed by Indiana University EUS physicians.
- Trial name
- NCT05521685
- Testing
- Endoscopic Ultrasound (EUS) administration of cyanoacrylate tissue adhesive to control bleeding gastric varices
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Indiana University
Malignant Bilio-pancreatic Diseases
Feasibility and Safety of a Dedicated Biliary Stent for Transmural EUS-guided Hepatico-gastrostomy: the FIT Study
One of the major roles of interventional EUS is biliary drainage (EUS-BD) as an alternative to ERCP-based biliary decompression. In fact, even when performed by expert endoscopists, ERCP-based stenting fails in 5% of cases.
- Trial name
- FIT (NCT04403893)
- Testing
- HANARO biliary stent placement
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Clinico Humanitas
Lymphadenitis
Linear Endosonography for the Assessment of Sarcoidosis Stage O
Patients are often referred for E(B)US examination and sampling of enlarged mediastinal and/or hilar lymph nodes that are not visible on a standard chest X-ray but are discovered by accident on CT scan performed outside the…
- Trial name
- LASSO (NCT01383226)
- Testing
- Thoracic endosonography
- Where
- 9 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gastric Subepithelial Tumors
Endoscopic Ultrasound-guided Needle-based Confocal Laser Endomicroscopy for Diagnosis of Gastric Subepithelial Tumors
The differential diagnosis of gastric subepithelial tumors by endoscopic ultrasound is currently suboptimal. Needle-based confocal laser endomicroscopy (nCLE) is a novel endoscopic technique, which is compatible with the 19-gauge…
- Trial name
- NCT02936986
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Shandong University
Pancreatic Cancer
Trial Comparing 19 and 25G Needles for Fine Needle Aspiration (FNA) of Solid Pancreatic Mass Lesions Greater Than 35mm
This study will test two different needles for performing a biopsy of the pancreas during endoscopic ultrasound (EUS) procedures.
- Trial name
- NCT01815606
- Testing
- biopsy with 19 gauge needle, biopsy with 25 gauge needle
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- AdventHealth
Liver Cirrhosis
EUS Share-wave in Patients With Liver Cirrhosis
Patients with chronic liver disease may develop progressive hepatic fibrosis. Liver cirrhosis should be detected at the early stages in order to avoid the complications related to these two conditions.
- Trial name
- NCT04644055
- Testing
- EUS- share wave of the liver
- Where
- Ecuador
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Pancreatic Cancer
Is One Pass Enough for the Diagnosis of the Pancreatic Masses During EUS-FNB?
Endoscopic ultrasonography (EUS) with tissue acquisition (TA) is nowadays a well-established technique for the sampling of solid lesions pancreatic and non-pancreatic lesions.
- Trial name
- ONE PASS (NCT05436704)
- Testing
- EUS-FNB
- Where
- Italy
- Volunteers
- 79 people
- Sponsor
- Istituto Clinico Humanitas Mater Domini
Pancreatic Cancer, Pancreas Adenocarcinoma
Drug Screening of Pancreatic Cancer Organoids Developed From EUS-FNA Guided Biopsy Tissues
We are going to establish "organoid" models from pancreatic cancer biopsies achieved via EUS-FNA. Then the sensitivity of the selected FDA-approved anti-cancer drugs will be tested in these organoids.
- Trial name
- NCT03544255
- Testing
- Biopsy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Ying Lv
Biliary Obstruction, Pancreas Neoplasm
EUS-guided Choledochoduodenostomy for Primary Drainage of Malignant Distal Biliary Obstruction
A prospective single-centre pilot study investigating the feasibility and safety of EUS-guided choledochostomy as primary drainage strategy in patients with distal malignant biliary obstruction using a FCSEMS through LAMS to…
- Conditions
- Biliary Obstruction, Pancreas Neoplasm, Distal Cholangiocarcinoma
- Trial name
- SCORPION-II-p (NCT05595122)
- Testing
- EUS-CDS
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Non Small Cell Lung Cancer
Combined Application of EBUS and EUS in Lung Cancer
This study aims to investigate a diagnostic yield and performance characteristics according to the order of endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) and endoscopic ultrasound-with…
- Trial name
- NCT01385111
- Testing
- EUS-B-FNA followed by EBUS-TBNA, EBUS-TBNA followed by EUS-B-FNA
- Where
- South Korea
- Volunteers
- 162 people
- Sponsor
- National Cancer Center, Korea
Other Specified Disorders of Esophagus, Stomach or Duodenum
EUS-FNA Versus KHB in Diagnostics of Upper Gastrointestinal Submucosal Tumors
Upper Gastrointestinal Submucosal Tumors are tumors arising from subepithelial layers of esophageal, gastric or duodenal wall. They usually have an intact mucosa lining on the inner surface.
- Trial name
- NCT02025244
- Testing
- Key Hole Biopsy ( KHB), EUS-FNA
- Where
- 2 sites in Czechia
- Volunteers
- 52 people
- Sponsor
- Vitkovice Hospital
Pancreatitis, Pancreatic Carcinoma
Endoscopic Ultrasound (EUS) Processor Comparison
The primary objective for this study is to compare the image quality of two endoscopic ultrasound (EUS) processors used for imaging of the pancreas.
- Trial name
- NCT01814631
- Testing
- image quality and resolution
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- AdventHealth
Biliary Obstruction, Pancreatic Cancer
LAMS Choledochoduodenostomies: With or Without Coaxial Plastic Stent
The aim of the study is to evaluate technical, clinical and safety outcomes of lumen-apposing metal stent (LAMS) with and without a coaxial double-pigtail plastic stent (DPS) in EUS-guided choledochoduodenostomies (CDS) for the…
- Conditions
- Biliary Obstruction, Pancreatic Cancer, Biliary Tract Neoplasms
- Trial name
- BAMPI (NCT04595058)
- Testing
- Double pigtail plastic stent through lumen-apposing metal stent, Lumen-apposing metal stent without double pigtail plastic stent
- Where
- 2 sites in Spain
- Volunteers
- 123 people
- Sponsor
- Hospital Universitari de Bellvitge
Tumors of the Pancreas, Submucosal Tumor of Gastrointestinal Tract (Disorder)
Prospective Evaluation of the Diagnostic Efficacy of a EUS Guided FNB Needle (AQUIRE®)
The present study investigates the efficacy of a new Endoultrasound guided fine needle biopsy (EUS-FNB) device (AquireTM Boston Scientific= AQUIRE®) for obtaining histological tissue cylinders in the diagnosis of solid pancreatic…
- Conditions
- Tumors of the Pancreas, Submucosal Tumor of Gastrointestinal Tract (Disorder), Lymph Node Disease
- Trial name
- NCT03621852
- Testing
- Endoultrasound guided FNB
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Philipps University Marburg
Gallbladder Disease, Pancreatitis
Prospective Evaluation of Idiopathic Pancreatitis: Role of Endoscopic Ultrasonography
The purpose of the study is to determine the best evaluation for patients with idiopathic (unexplained) pancreatitis.
- Trial name
- NCT00609726
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham