Clinical trials: EUS Guided Biopsy
Autoimmune Pancreatitis
EUS-guided Procore-biopsy in Diagnosing Autoimmune Pancreatitis
The goal of this prospective study is to evaluate the feasibility of the Core Biopsy Needle with reverse bevel (Procore TM) in diagnosing autoimmune pancretitis
- Trial name
- NCT01774513
- Testing
- Procore-Needle
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Technical University of Munich
Solid Pancreatic Masses
Endoscopic Ultrasound-guided Fine Needle Biopsy With 25-gauge Biopsy Needles for Solid Pancreatic Masses
For 12 months after approvement by the University of Yonsei institutional review board, of the 59 patients older than 20 years referred to our medical center for EUS-FNA or FNB, all consecutive pancreatic lesions were evaluated…
- Trial name
- NCT01795066
- Testing
- EUS-FNB with 25-gauge (Echotip ProCore; Cook Endoscopy Inc, Limerick, Ireland)
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Yonsei University
Pancreatic Carcinoma, Pancreatic Neuroendocrine Tumor
Study on Microflora Characteristics of Pancreatic Solid Lesions Via Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy
Study objective: To describe the microflora characteristics of the pancreatic solid lesions via the tissue acquired via the endoscopic ultrasound-guided fine needle aspiration/biopsy (EUS-FNA/B).
- Conditions
- Pancreatic Carcinoma, Pancreatic Neuroendocrine Tumor, Autoimmune Pancreatitis, Microflora
- Trial name
- NCT05171517
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Pancreatic Masses
RCT Comparing Accuracy Among Franseen, Forward-bevel Westcott, and Fork-tip EUS-FNB Needle in Diagnosis of Solid Pancreatic Lesions
Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) is a well-established technique for pancreatic tissue acquisition, offering a high diagnostic accuracy ranging from 78% to 95%, along with a favorable safety profile.
- Trial name
- NCT07032974
- Testing
- Franseen, Forward-bevel, Fork-tip
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Mahidol University
Pancreatic Cancer, Pancreatic Adenocarcinoma
Pancreatic Cancer Models Developed From EUS Guided Biopsy Tissue
Pancreatic cancer is a very aggressive cancer. Over the past 40 years there has not been much progress made in reducing deaths from this cancer.
- Conditions
- Pancreatic Cancer, Pancreatic Adenocarcinoma, Pancreatic Cyst
- Trial name
- NCT03140592
- Testing
- Biopsy
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Stony Brook University
Gastrointestinal Subepithelial Tumors
EUS-guided Fine Needle Aspiration (EUS-FNA) Versus EUS-guided Fine Needle Biopsy (EUS-FNB) for Diagnosis of Subepithelial Tumors
Background: Preoperative pathologic diagnosis of subepithelial tumor (SET) can improve clinical decision making. Although EUS-guided fine needle aspiration (FNA) is currently considered the standard method for sampling SET, its…
- Trial name
- NCT02943837
- Testing
- Device: 22G FNA needle, Device: 20G FNB needle
- Sponsor
- Asan Medical Center
Pancreatic Ductal Adenocarcinoma
A Clinical Study to Evaluated Which Number of Passes of EUS-FNB is Better for Culturing Primary Cells of PDAC
The Aim of this study is to investigate the amount of tissue required for the successful culture of primary cells from human-derived pancreatic ductal adenocarcinoma which obtained by endoscopic ultrasound-guided fine-needle…
- Trial name
- NCT04794140
- Testing
- different number of passes
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Liver Biopsy
Endoscopic Ultrasound vs Percutaneous Route for Liver Biopsy
This study is to evaluate and directly compare the technical success, tissue quality, diagnostic efficacy and safety profile of Percutaneous and Endoscopic Ultrasound-guided Liver Biopsy.
- Trial name
- NCT04003766
- Testing
- biopsy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- AdventHealth
Pancreatic Cyst
EUS-guided Through-the-needle Microforceps Biopsy Outcomes
INTRODUCTION: The diagnosis of pancreatic cystic lesions (PCLs) is increasing due to improvements of cross-sectional imaging. It is mandatory, for appropriate management, to make an accurate diagnosis and risk stratification…
- Trial name
- NCT04140435
- Testing
- EUS-guided through-the-needle microbiopsy forceps (Moray)
- Where
- Argentina
- Volunteers
- 50 people
- Sponsor
- Institute of Gastroenterology and Advance Endoscopy
Pancreatic Cancer
EUS- and US- Guided Biopsy for Pancreatic Lesion
Endoscopic ultrasound (EUS) and ultrasound (US) are the two primary imaging modalities used to guide pancreatic needle biopsy. This study aimed to compare the diagnostic performance and complications associated with EUS- and…
- Trial name
- NCT07138976
- Testing
- sampling tissue
- Volunteers
- 2,517 people
- Sponsor
- Tian'an Jiang
Portal Hypertension, Chronic Liver Disease
EUS vs TJ for Liver Biopsy and Portal Pressure Gradient Measurement
This study will directly compare the endoscopic ultrasound guided approach to obtain adequate liver biopsies and portal pressure gradient measurements to the current standard of care which uses the transjugular approach.
- Conditions
- Portal Hypertension, Chronic Liver Disease, Cirrhosis
- Trial name
- NCT05118308
- Testing
- Transjugular hepatic venous pressure gradient measurement with liver biopsy, Endoscopic ultrasound portal pressure gradient measurement with liver biopsy
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Non-alcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis
Endoscopic Ultrasound(EUS)-Guided TRUCUT Biopsy (EUS-TCB) of Suspected Nonalcoholic Fatty Liver Disease(NAFLD.)
Endoscopic Ultrasound involves the placement of a small flexible camera through the mouth and into the stomach to image various parts of the body.
- Trial name
- NAFLD (NCT00586313)
- Testing
- Tru-cut biopsy, Tru-cut
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Indiana University
Subepithelial Tumors of the Upper Gastrointestinal Tract
22-G-Procore Needle for the Diagnosis of SETs of the Upper GI Tract
The goal of this prospective study is to evaluate the feasibility of the 22-G Core Biopsy Needle with reverse bevel (Procore TM) in biopsy sampling of subepithelial tumors of the upper gastrointestinal tract.
- Trial name
- PRO-SET (NCT01726010)
- Testing
- 22-G Procore Needle
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
EUS Guided Biopsy
SharkCore Versus Acquire FNB
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) has been established as an effective technique for sampling tissue inside and around the gastrointestinal tract, including the pancreas, liver, lymph nodes, and…
- Trial name
- NCT03672032
- Testing
- Fork-tip Needle, Franseen Needle
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Henning Gerke
Pancreatic Diseases
Fine-needle Biopsy Combined With Macroscopic On-site Evaluation for Diagnosis of Solid Pancreatic Lesions
The goal of this clinical trial is to compare the diagnostic efficacy, core tissue acquisition ability, number of punctures and puncture time of macroscopic on-site evaluation (MOSE) and two punctures alone in Endoscopic…
- Trial name
- NCT06994611
- Testing
- MOSE application, Conventional processing
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Changhai Hospital
Pancreatic Neoplasms, Pancreatic Cancer
On-site Cytopathology EUS-FNA
This study is a multicenter prospective randomized controlled trial. Potential participants in this study include patients referred for Endoscopic Ultrasound-guided fine needle aspiration (EUS-FNA) of a solid pancreatic lesion at…
- Trial name
- NCT01386931
- Testing
- EUS-guided FNA performed with on-site Cytopathologist, EUS-guided FNA performed without on-site Cytopathologist
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- University of Colorado, Denver
Adenocarcinoma, Neuroendocrine Tumors
EchoTip AcuCore Post-Market Clinical Study
The purpose of collecting this data is to continue to learn more about the EchoTip AcuCore and the device's ability to produce the desired favorable effect and if there are any undesired outcomes that may be related to the…
- Conditions
- Adenocarcinoma, Neuroendocrine Tumors, Hepatocellular Carcinoma, Cholangiocarcinoma
- Trial name
- NCT06358001
- Testing
- EchoTip AcuCore
- Where
- 8 sites in United States
- Volunteers
- 183 people
- Sponsor
- Cook Research Incorporated
Lung Cancer
Significance of Ultrasound Elastography in Lymph Node
Background and Objectives: Elastography can reflect the difference of tissue hardness, which helps to identify the difference of hardness between benign and malignant tissues.
- Trial name
- NCT03391557
- Testing
- UE
- Volunteers
- 42 people
- Sponsor
- Fangsurong
Diagnoses Diseases, Ultrasound Therapy; Complications
19 Versus 22-Gauge Needle for EUS-LB
Chronic liver disorders (CLD) are a major cause of morbidity and mortality for individuals in the US. Though serologic analysis will often lead to a conclusive diagnosis, liver biopsy remains an important method for helping to…
- Conditions
- Diagnoses Diseases, Ultrasound Therapy; Complications, Liver Diseases
- Trial name
- EUSLB1922 (NCT02967991)
- Testing
- EUS-guided liver biopsy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Endoscopic Ultrasonography-guided Fine Needle Aspiration, Sedation Complication
Safety and Efficacy Evaluation of Remimazolam for Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy
This study aims to compare the safety and efficacy of remimazolam and propofol in EUS-FNA/FNB sedation. This study is a prospective, single-blind study.
- Conditions
- Endoscopic Ultrasonography-guided Fine Needle Aspiration, Sedation Complication, Remimazolam
- Trial name
- NCT05437497
- Testing
- Remimazolam Injection, Propofol Injection
- Where
- China
- Volunteers
- 264 people
- Sponsor
- The Third Xiangya Hospital of Central South University