Clinical trials: Ear Infection
Otitis Externa, Otorhinolaryngologic Diseases
Safety and Efficacy of Once-Daily Dosing of FoamOtic Cipro Compared to Twice-Daily Dosing of Ciloxan Ear Drops in Patients With Acute External Otitis
The purpose of this study is to assess the Safety and Efficacy of Foam Otic Cipro (0.3% Ciprofloxacin Otic Foam), used once-daily for 7 days for the treatment of Acute Diffuse Otitis Externa, compared to commercial ear drops used…
- Conditions
- Otitis Externa, Otorhinolaryngologic Diseases, Ear Diseases, Otitis
- Trial name
- Once-a-day (NCT01157819)
- Testing
- 0.3% Ciprofloxacin Ear Drops, FoamOtic Cipro
- Where
- 2 sites in Israel
- Volunteers
- 70 people
- Sponsor
- Otic Pharma
Otitis Media, Infections, Respiratory Tract
Study to Evaluate the Safety and Clinical Efficacy of Augmentin® Extra Strength-600 in Children With Acute Otitis Media in India
Augmentin (ES)-600 is a high-dose amoxicillin/clavulanic acid 14:1 formulation that allows administration at 90/6.4 milligrams (mg)/kilograms (kg)/day in two divided doses.
- Conditions
- Otitis Media, Infections, Respiratory Tract, Respiratory Tract Infections
- Trial name
- NCT04600752
- Testing
- Augmentin (ES)-600
- Where
- 13 sites in India
- Volunteers
- 310 people
- Sponsor
- GlaxoSmithKline
OTITIS MEDIA WITH EFFUSION
Tympanostomy Tube Extrusion Time & Viscosity
Studies have focused on the factors that influence tympanostomy tube (TT) extrusion may contribute to the management of OME. In this study the investigators aimed to assess the correlation between the TT extrusion time and…
- Trial name
- NCT03848026
- Testing
- Middle ear fluid viscosity, Tympanostomy tube extrusion time
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Bezmialem Vakif University
Acute Otitis Media
Amoxicillin Clavulanate in Treatment of Acute Otitis Media
This is a prospective, randomized, double-blind, placebo controlled one-center study carried out in primary care setting of the health center of City of Turku, Finland.
- Trial name
- NCT00299455
- Testing
- amoxicillin-clavulanate
- Where
- 2 sites in Finland
- Volunteers
- 320 people
- Sponsor
- University of Turku
Otomycosis, Fungal Ear Infection
Terbinafine Hydrochloride for the Treatment of Otomycosis
Otomycosis is a fungal infection of the ear that often causes itching, pain, ear discharge, and hearing problems. It is more common in hot and humid climates and in people with risk factors such as diabetes, frequent use of…
- Trial name
- NCT07152327
- Testing
- Terbinafine Hydrochloride Cream
- Volunteers
- 50 people
- Sponsor
- Assiut University
Chronic Suppurative Otitis Media, Mastoid Cavity
Study the Impact of the Mastoid and Middle Ear Volume on the Success of Type 1 Tympanoplasty in Pediatric Age, With Comparing Using Cartilage and Fascial Grafts Through This, Strength the Hypothesis of That Total Tympanometry Volume Correlates With Ventilated Mastoid Air Cells Volume on CT Scans
The goal of this observational study is to know the impact of the mastoid and middle ear volume on the success of type 1 tympanoplasty in pediatric age, with a closer view on the comparison of using cartilage and fascial grafts…
- Conditions
- Chronic Suppurative Otitis Media, Mastoid Cavity, Pneumatization, Tympanoplasty
- Trial name
- NCT07806461
- Testing
- tympanoplasty type 1, Audiological Evaluation, HRCT scan temporal bone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Acute Otitis Media, Chronic Otitis Media
Anesthetic Effect of Lidocaine/Epinephrine Solution Delivered Via Iontophoresis to External Auditory Apparatus
This is a non-randomized, multicenter, prospective, clinical study intended to evaluate the effectiveness of a method for iontophoretic delivery of a buffered lidocaine/epinephrine solution for provision of tympanic membrane…
- Conditions
- Acute Otitis Media, Chronic Otitis Media, Recurrent Acute Otitis Media
- Trial name
- IONTO (NCT00941993)
- Testing
- Iontophoresis System (Acclarent)
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Integra LifeSciences Corporation
Hearing Loss, Hearing Loss, Sensorineural
Single-sided Deafness and Cochlear Implantation
This observational study evaluates the effects of cochlear implantation in patients with deafness in one ear.
- Conditions
- Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Unilateral, Hearing Loss, Sudden
- Trial name
- NCT05052944
- Testing
- Cochlear implantation
- Where
- 5 sites in United States
- Volunteers
- 78 people
- Sponsor
- Johns Hopkins University
Chronic Suppurative Otitis Media
Pazufloxacin Mesilate Ear Drops in Patients With Chronic Suppurative Otitis Media
Objective To observe the safety and tolerability of Pazufloxacin Mesylate Ear Drops of different concentrations in patients with simple chronic suppurative otitis media.
- Trial name
- NCT03675841
- Testing
- Pazufloxacin Mesilate ear drops
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Lee's Pharmaceutical Limited
Otomycosis
Antifungal Potential of Moringa Olifera Against Otomycosis
patients with Otomycosis were recognized by an ENT specialist. 20 patients were distributed randomly into two groups. The first group will be treated with Nystatin ear drops twice daily.
- Trial name
- NCT04768829
- Testing
- Moringa oleifera leaf 10mg/100ml, Ear Drop
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Deraya University
Acute Otitis Media
A Phase III Study of an Otic Formulation in Acute Otitis Media With Tympanostomy Tubes
The purpose of this study is to determine if an otic formulation is safe and effective in treating middle ear infections in patients with ear tubes.
- Trial name
- NCT00578474
- Testing
- Moxidex otic solution, Ofloxacin otic solution, Tympanostomy tubes
- Volunteers
- 911 people
- Sponsor
- Alcon Research
Upper Respiratory Tract Infections
LiveSpo Navax® Supports the Treatment of Acute Rhinosinusitis and Otitis Media
Acute respiratory tract infections (ARTIs), such as acute rhinosinusitis (ARS) and acute otitis media (AOM), are common worldwide and caused by viruses or bacteria entering the body through the mouth and nose.
- Trial name
- NCT05804123
- Testing
- 0.9% NaCl physiological saline Nasal-spraying, LiveSpo Navax®, Augmentin 500Mg Tablet
- Where
- Vietnam
- Volunteers
- 175 people
- Sponsor
- Anabio R&D
Pain, Postoperative, Otitis Media
Ketorolac Sublingual vs. Fentanyl Intranasal in Pain Control for Bilateral Myringotomy and Tubes (BMT) Placement in Children
The purpose of this study is to compare the efficacy and safety of ketorolac sublingual with fentanyl intranasal used in our hospital for pain control in children undergoing bilateral myringotomy with placement of pressure…
- Trial name
- NCT02653742
- Testing
- Ketorolac, Fentanyl
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Anica Crnkovic
Otomycosis
Comparative Efficacy of Topical Clotrimazole Versus 2% Salicylic Acid in Otomycosis
Otomycosis is a fungal infection of the outer ear canal that commonly causes itching, discomfort, discharge, and a feeling of blockage in the ear.
- Trial name
- NCT07535424
- Testing
- clotrimazole, 2% Salicylic Acid
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Mayo Hospital Lahore
Stroke, Mild Cognitive Impairment (MCI)
Telerehabilitation Decision Support System: Pilot Testing Protocol
This study follows the successfully completed HOLOBalance project which was funded by the EU Horizon 2020 scheme. TheHOLOBalance platform delivers exercises demonstrated via a hologram of the physiotherapist and corrected in real…
- Conditions
- Stroke, Mild Cognitive Impairment (MCI), Vestibular Disease, Long Covid-19
- Trial name
- TeleRehab DSS (NCT07079787)
- Testing
- TeleRehab DSS Pilot Test
- Where
- 5 sites in Germany, Greece and 3 more
- Volunteers
- 30 people
- Sponsor
- University College, London
Otitis Media With Effusion
Laser Acupuncture for Otitis Media With Effusion in Children
The goal of this clinical trial is to learn if laser acupuncture (LA) can improve middle ear function and reduce the recurrence of Otitis Media with Effusion (OME) in children.
- Trial name
- NCT07242001
- Testing
- Laser Acupuncture
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Recurrent Urinary Tract Infection
Acupuncture for Prevention of Recurrent Urinary Tract Infections.
In this multi-centre prospective randomized controlled trial the efficacy of segmental acupuncture in the prevention of recurrent urinary tract infections will be assessed.
- Trial name
- SARUTI (NCT02705495)
- Testing
- acupuncture, Cranberry products
- Where
- Austria
- Volunteers
- 136 people
- Sponsor
- Medical University of Graz
Otitis Media With Effusion, Food Hypersensitivity
Food Allergy - Tubes - Adenoids (FATA) Trial
The questioned proposed by this study is one of treatment: "To what extent does simultaneous BMT (Bilateral Myringotomy with Tympanostomy Tubes), adenoidectomy, and diagnosis/avoidance of food allergy affect the frequency of…
- Trial name
- FATA (NCT00736112)
- Testing
- Food Allergy Testing, Adenoidectomy, BMT
- Where
- United States
- Sponsor
- University of Missouri-Columbia
Diabetic Foot Ulcer, Coronary Artery Disease
Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT)
This pilot study wants to determine to which extent SPCCT allows obtaining images with improved quality and diagnostic confidence when compared to standard Dual Energy CT (DECT), both with and without contrast agent injection.
- Conditions
- Diabetic Foot Ulcer, Coronary Artery Disease, Parenchymatous; Pneumonia, Kidney Stone
- Trial name
- SPEQUA (NCT04328181)
- Testing
- Spectral Photon Counting Computed Tomography (SPCCT), DECT (Dual Energy CT)
- Where
- France
- Volunteers
- 339 people
- Sponsor
- Hospices Civils de Lyon
Suppurative Otitis Media
The Microbiome Variability and Antibiotic Resistance of Chronic Suppurative Otitis
ear swabs will be collected from 120 patients with established CSOM at the ear-nose-throat (ENT) outpatient clinic at the Ziv medical center, and 120 swabs will be taken from children with Otitis Media with Effusion (OME)…
- Trial name
- NCT03456739
- Volunteers
- 240 people
- Sponsor
- Ziv Hospital