Clinical trials: Ear Noise
Ear Noise, Tinnitus, Noise Induced
Multimodal Therapy for Somatosensory Tinnitus
Tinnitus (ringing or buzzing in the ears) affects approximately 10-15% of the adult population and significantly reduces quality of life in many patients.
- Conditions
- Ear Noise, Tinnitus, Noise Induced, Tinnitus, Subjective, Headache Other
- Trial name
- SOMATIN (NCT07468318)
- Testing
- Multimodal physiotherapy for TMJ and Cervical spine, Combined Exercise Program (Aerobic + Resistance + Breathing), Tinnitus-Specific Psychological Support
- Where
- Czechia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Hearing Loss
Evaluation of the Global Auditory Nerve Activity for Exploration of Hearing in Humans
To date, all the electrophysiological methods for auditory testing rely on the measure on synchronous evoked auditory nerve activity.
- Trial name
- MELAUDI-2 (NCT03552224)
- Testing
- Recording of auditory nerve activity
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Tinnitus, Chronic Subjective Tinnitus
Acute Nicotine Gum and Tinnitus Loudness in Non-Smoking Adults
This study tested whether a single dose of nicotine gum can reduce the loudness of tinnitus (ringing in the ears) in non-smoking adults with chronic tinnitus.
- Trial name
- NCT07772089
- Testing
- Nicotine polacrilex gum 4 mg
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- San Diego State University
Hearing Loss
Daily Exposure Monitoring to Prevent Hearing Loss
The goal of this study is to determine whether daily assessment and feedback of workers' noise exposures leads to more effective use of hearing protection and prevention of noise-induced hearing loss.
- Trial name
- DEMON (NCT01714375)
- Testing
- QuietDose Device
- Where
- United States
- Volunteers
- 322 people
- Sponsor
- Yale University
Tinnitus
Manual Acupuncture for Acute Primary Tinnitus
This clinical trial aims to assess the efficacy of manual acupuncture for patients with acute primary tinnitus.
- Trial name
- NCT07515482
- Testing
- Manual acupuncture, Usaual care
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Dan Bing
Tinnitus
Internet-based Self-help for Tinnitus: The Role of Support
Internet-based cognitive behavioural self-help (iCBT) has become increasingly popular to provide psychotherapy. For several psychological and psychosomatic disorders, treatment efficacy was shown.
- Trial name
- NCT01927991
- Testing
- iCBT (internet-based, cognitive-behavioural therapy)
- Where
- Germany
- Volunteers
- 112 people
- Sponsor
- Philipps University Marburg
Meniere's Disease, Ménière's Disease
SPI-1005 for the Treatment of Meniere's Disease (Open Label)
Study of the safety of open-label SPI-1005 400 mg BID treatment in adults with Meniere's Disease (MD) for 6 or 12 months to support chronic or chronic intermittent use.
- Trial name
- NCT06859788
- Testing
- Ebselen
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Retrocochlear Pathology, Auditory Processing Disorder, Central
Cochlear Implantation in Single Sided Deafness and Asymmetrical Hearing Loss: a Cost/Utility Study.
The investigators assume that cochlear implants in this indication are not only effective but also cost-effective. The investigators' experimental protocol relies on real life therapeutic strategy, where a cochlear implant may be…
- Conditions
- Retrocochlear Pathology, Auditory Processing Disorder, Central, Major Cochlear Ossification or Malformation
- Trial name
- CISSD (NCT02204618)
- Testing
- cochlear implantation, 6 months initial abstention
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Toulouse
Hyperacusis
Intervention for Reduced Sound Tolerance
Hyperacusis is the intolerance to sound levels that normally are judged acceptably loud to others. The presence of hyperacusis (diagnosed or undiagnosed) can be an important reason why some persons reject amplified sound from…
- Trial name
- NCT00890526
- Testing
- Sound Therapy (Tinnitus Retraining Therapy), Counseling (Tinnitus Retraining Therapy), No Counseling
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Alabama, Tuscaloosa
Tinnitus, Subjective, Hearing Impairment
Efficacy of Amplification With Hearing Aids for Tinnitus Relief
This study evaluates the treatment efficacy of tinnitus in people with mild hearing loss. One-third of participants will use hearing aid, one-third of participants will use customized music, while the other one-third participants…
- Trial name
- NCT03716544
- Testing
- Amplification with hearing aid, Customized music
- Where
- Hong Kong
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong
Sudden Sensorineural Hearing Loss, Tinnitus
The Development of Tinnitus in Patients With SSNHL: Insights From fMRI and Metabolomics
The goal of this clinical trial is to investigate the factors and mechanisms underlying tinnitus generation and chronification in patients with sudden sensorineural hearing loss (SSNHL) .
- Trial name
- NCT06355102
- Testing
- Conventional treatment and care
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Tinnitus
Navigated Repetitive TMS for Chronic Tinnitus
This study is testing whether a special type of brain stimulation called neuronavigated TMS can help reduce tinnitus (ringing in the ears).
- Trial name
- NCT07435298
- Testing
- navigated rTMS
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Tinnitus
Fudan Tinnitus Doctor for Tinnitus Management
The goal of this clinical trial is to evaluate whether a conversational artificial intelligence-based digital intervention can improve symptoms in adults with chronic subjective tinnitus.
- Trial name
- NCT07558837
- Testing
- Fudan Tinnitus Doctor (FTD) System, Non-conversational Digital Education Program
- Where
- China
- Volunteers
- 256 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Tinnitus
Genetically-informed Behavioral and Cognitive Interventions for the Management of Tinnitus
Psychological and behavioral interventions, such as Cognitive Behavioral Treatment (CBT) and Tinnitus Retraining Therapy (TRT), are commonly applied either alone or in combination for the management of tinnitus but selection of…
- Trial name
- NCT04675112
- Testing
- Cognitive Behavioral Treatment (CBT) and Tinnitus Retraining Therapy (TRT)
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gkouskou Kalliopi
Tinnitus
Multidimensional Phenotyping of Patients With Tinnitus Using Electronic Health Records and a Specialty Database
This retrospective observational study will use historical electronic health record and tinnitus specialty database data from adult patients with tinnitus seen at the Eye and ENT Hospital of Fudan University between January 2015…
- Trial name
- NCT07887932
- Volunteers
- 225,792 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Tinnitus
FR-taVNS Tinnitus Tria
Tinnitus is a common neurosensory symptom affecting 12-30% of adults and is closely associated with anxiety, sleep disturbance, and autonomic dysregulation.
- Trial name
- NCT07711639
- Testing
- True Foot Reflexology, True ta-VNS, True Auricular Acupressure
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Tzu Chi University
Tinnitus
TIDE Project: Biomarker Discovery for Chronic Tinnitus Diagnosis
Research in clinical neuroscience is founded on the conviction that a better understanding of tinnitus related changes of brain function will improve our ability to diagnose and treat tinnitus.
- Trial name
- TIDE (NCT06520865)
- Testing
- Acoustic paradigms
- Where
- 7 sites in United States, Belgium and 3 more
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- University of Regensburg
Hearing Loss, Hearing Disorders in Children
Preschool Hearing Screening
Children who are deaf or hard-of-hearing (D/HH) are at risk of speech and language delays, which can be mitigated through early identification and intervention.
- Conditions
- Hearing Loss, Hearing Disorders in Children, Hearing Loss, Sensorineural, Hearing Loss, Conductive
- Trial name
- NCT06058767
- Testing
- Otoacoustic Emissions Testing, Pure Tone Audiometry
- Where
- United States
- Volunteers
- 13,764 people
- Sponsor
- University of California, San Francisco
Tinnitus
Treating Tinnitus Using Eutectic Mixture of Local Anesthetics (EMLA) 5% Cream
The investigators like to learn whether EMLA cream 5% helps tinnitus patients. so far it is known that lidocaine I.V do helps tinnitus but until now it is not clear if topical anaesthetics (e.g EMLA cream) helps tinnitus.
- Trial name
- NCT02266160
- Testing
- EMLA cream 5%, cetomacrogol cream (lotion cream)
- Volunteers
- 142 people
- Sponsor
- HaEmek Medical Center, Israel
Tinnitus, Subjective Tinnitus
Efficacy and Safety of the Soricle for Subjective Tinnitus Relief
This study was conducted to evaluate the efficacy and safety of Soricle, a medical device combining transcutaneous vagus nerve stimulation and sound stimulation, in patients with subjective tinnitus.
- Trial name
- NCT07548320
- Testing
- tVNS Device, tVNS + Sound Stimulation Device
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Neurive Co.,Ltd.