Clinical trials: Early Cancer Detection
Cervical Cancer Screening
Community Implementation of Urine HPV Test and Reflex DNA Methylation Test in Cervical Cancer Screening
Aims: The project aims to explore the acceptability and feasibility of a self-sampling, urine-based HPV test (INDICAID HPV Urine Test) in a community setting, and the effectiveness of DNA methylation test for triaging high-risk…
- Trial name
- NCT07468578
- Where
- Hong Kong
- Volunteers
- 8,620 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Breast Cancer
Artificial Intelligence in Mammography-Based Breast Cancer Screening
Breast cancer (BC) is the most common cancer among women in worldwide and the second leading cause of cancer-related death. As the corner stone of BC screening, mammography is recognized as one of useful imaging modalities to…
- Trial name
- NCT04156880
- Testing
- mammography
- Where
- Hong Kong
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colonoscopy, Colonic Polyps
Implementation of Optical Diagnosis for Diminutive Polyps Amongst Endoscopists: Training and Long-term Quality Assurance
In this study, Dutch gastroenterologists who are certified for performing colonoscopies on FIT-positive patients in the Dutch population screening program are trained in optical diagnosis with validated methods.
- Trial name
- DISCOUNT2 (NCT02407925)
- Testing
- Feedback
- Where
- 13 sites in Netherlands
- Volunteers
- 3,144 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
High Risk Cancer, Lung Cancer
Retrospective Clinical Trial Comparing Radiologists' Diagnosis Accuracy in Lung Cancer Screening Population With and Without the Help of an AI/ML Tech-based SaMD
This is a two arm, randomized, controlled, blinded, multi-case multi reader (MRMC), retrospective study for the evaluation of the efficacy and safety of an AI/ML technology-based CADe/x developed to detect, localize and…
- Trial name
- RELIVE (NCT06751576)
- Testing
- Median LCS
- Where
- 5 sites in United States, Spain
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Median Technologies
Breast Cancer
Assessment of Automated Breast Ultrasound
The investigators are interested in assessing the value of and comparing the use of automated breast ultrasound (ABUS) (either as a primary screening approach or as a supplementary procedure) with digital breast tomosynthesis…
- Trial name
- NCT02386176
- Where
- United States
- Volunteers
- 598 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Mammography Screening, Geriatrics
Overdiagnosis and Breast Cancer Screening Decisions
This is a survey-based study using an online panel. The goal of the study is to understand whether information about overdiagnosis influences breast cancer screening intention among older women.
- Conditions
- Mammography Screening, Geriatrics, Decision Aid
- Trial name
- NCT07071415
- Testing
- Breast cancer screening decision aid -- low risk, Breast cancer decision aid -- moderate risk, Breast cancer screening decision aid -- high risk
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Yale University
Breast Cancer
Ultrasound-based Breast Cancer Screening in Chinese Women
In the present study, the investigators will screen breast cancer of the Chinese women based on ultrasound and aim to compare the risk evaluation model of PUMCH model which was established by our previous work with other risk…
- Trial name
- NCT02268643
- Testing
- ultrasound plus clinical breast examination
- Where
- 16 sites in China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Cervical Cancer
Dissemination of Cervical Cancer Screening to Primary Care Physicians in Underserved Communities
Primary care physicians have an important role to play in the delivery of cancer prevention and detection services to patients. Face-to-face counseling of physicians, called academic detailing, involves a brief and focused…
- Trial name
- NCT00629993
- Testing
- Academic Detailing
- Where
- United States
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Columbia University
Internet Addiction Disorder
Evaluation of a Therapeutic Education Application in the Treatment of Young People with Moderate or Problematic Screen Use
This single-center, controlled, and randomized study evaluates the effectiveness of the Phonix Care app in regulating screen use among young people aged 11 to 25.
- Trial name
- PHONIX CARE (NCT06648538)
- Testing
- Phonix Care
- Where
- France
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Cognitive Impairment
Effect of Technology on Cognitive Function in Elderly
Cognitive technology therapies, including interactive video gaming, computer soft wares and mobile technology, have been used to implement cognitive training and rehabilitation programs.
- Trial name
- cogntion (NCT06378606)
- Testing
- cognitive therapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nourhan Hesham Ali
Cervical Cancer Screening, Human Papilloma Virus
Developing and Implementing HPV SCREENED
This study will assess the feasibility of implementing HPV self-sampling as a primary cervical cancer screening strategy for under-screened women in the emergency department (ED).
- Trial name
- NCT07657104
- Testing
- HPV Self-collection in the ED
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Oral Cancer, Precancerous Conditions
Oral Cancer Screening in Mumbai, India by Primary Health Care Workers
A feasibility study to compare the test characteristics of three different oral cancer screening techniques performed by trained primary health care workers:1)Unaided Visual Inspection, 2)VelScope Assisted Examination, and 3)…
- Trial name
- NCT00655421
- Testing
- Unaided Visual Inspection, VelScope, Toluidine Blue Assisted Oral Examination
- Where
- India
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Tata Memorial Hospital
Colorectal Cancer
The PharmFIT Study
This study will conduct a randomized controlled trial to assess the impact of a pharmacy-based FIT intervention, Pharmacy-based FIT (PharmFIT), on colorectal cancer screening (CRC) screening rates in primary care patients who are…
- Trial name
- PharmFIT (NCT06656936)
- Testing
- PharmFIT
- Where
- 2 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Sexually Transmitted Diseases
Comparing Specimen Collection Techniques to Screen for Sexually Transmitted Infections in Pregnant Women: A Pilot Study
The purpose of this research study is to compare two specimen collection techniques (vaginal vs. endocervical swab) to screen for sexually transmitted infections in pregnant women.
- Trial name
- NCT03877263
- Testing
- Endocervical swab for detection of STI, Vaginal swab for detection of STI
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- OhioHealth
Breast Cancer
Developing and Evaluating Culturally Relevant Interventions to Improve Breast Cancer Screening
The goal of this study is to evaluate the relative benefits of an intervention to promote breast cancer screening among women in the White Mountain Apache (WMA) community.
- Trial name
- NCT05665660
- Testing
- CARE, CARE + COACH
- Where
- United States
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Sedentary Behavior, Screen Time
StandUPTV: Reducing Sedentary Screen Time in Adults
The goal of this study is to develop an optimized intervention for reducing leisure sedentary screen time (SST) in middle-aged adults with overweight or obesity.
- Conditions
- Sedentary Behavior, Screen Time, Physical Activity, Sleep
- Trial name
- StandUPTV (NCT04464993)
- Testing
- Device-based feedback, self-monitoring, and education: CORE, Sedentary Screen Time lockout: LOCKOUT, Context-based prompts: TEXT
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Dermatologic Diseases, Outpatient Clinics, Hospital
Daily Screen Time Exposure in Dermatology Patients
The aim of this study is to determine the daily screen time (smartphone, computer/tablet and television) of all patients who visited a tertiary dermatology outpatient clinic within a specific period and to evaluate differences in…
- Trial name
- NCT07640763
- Where
- Turkey (Türkiye)
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Biruni University
Behavioral Economics, Primary Health Care
Primary Care Clinical Excellence Incentive Study
As part of UCLA Health's commitment to developing a premier integrated health system built on a foundation of physician-led, team-based primary care, the Department of Medicine (DOM) recently implemented a new performance based…
- Conditions
- Behavioral Economics, Primary Health Care, Health Maintenance, Diabetes
- Trial name
- PCCE (NCT04237883)
- Testing
- Standard communication email, Social comparison Intervention, Leadership Training
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Prostate Cancer
A Randomized Controlled Trial to Promote Physician-Patient Discussion of Prostate Cancer Screening
Prostate cancer is the most common type of cancer among men. It is also the second leading cause of cancer-related death among men.
- Trial name
- NCT00208988
- Testing
- Educational handout about prostate cancer screening, Simple cue for patient to talk to doctor
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Emory University
Lung Nodule
Non-Invasive ctDNA Methylation Detection for Lung Nodule Patients
Low-dose computed tomography (LDCT) is recommended for early-stage lung cancer screening. However, it is often difficult to determine indolent lesions from more aggressive tumors without an invasive intervention or prolonged…
- Trial name
- NCT03685669
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai Chest Hospital
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