Clinical trials: Early Cancer Detection
Colorectal Cancer
A Culturally-adapted Colorectal Cancer Screening Decision Aid Designed for American Indians
Experts note that in order to continue reducing the US cancer burden, it is critical that investigators "more completely apply discoveries in cancer prevention we have already made." Thus, it is important to research strategies…
- Trial name
- NCT03569761
- Testing
- Colorectal Cancer Screening Decision Aid, Control Group
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Colorectal Cancer
Low Literacy Intervention for Colorectal Cancer Screening
Of 17 performance measures of hospital quality regularly reported for the Veterans Administration (VA) health care system, rates of colorectal cancer screening are the lowest.
- Trial name
- NCT00012922
- Testing
- Low Literacy Intervention for Colorectal Cancer Screening
- Where
- United States
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Taurine in Cancer Colon
The Prospect of Using Serum Taurine Level as a Potential Biomarker for Early Detection of Colorectal Carcinoma and Its Correlation With Other Prognostic Markers
Serum taurine results in this study showed that, besides CRC biomarkers; it is most attractive, more precious and more accurate early biomarker for early detecting of any malignant change which may led to CRC by other mean it is…
- Trial name
- NCT04192539
- Testing
- Taurine
- Where
- Egypt
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Prostate Neoplasm
Prostate Cancer Screening Trial Using Imaging
Participants will be recruited from the community and attend a screening clinic and undergo the following screening tests: 1. Bi-parametric MRI - reported by a radiologist and CAD-AI system 2.
- Trial name
- PROSTAGRAM (NCT03702439)
- Where
- United Kingdom
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Cervical Cancer Susceptible Population Classification
Cervical Cancer Susceptible Population Classification
Cervical cancer is the third most common lethal tumor globally, causing around a quarter million deaths annually, despite the availability of HPV vaccines.
- Trial name
- NCT06405945
- Testing
- PCR and sequence
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Cancer Prevention
Increasing Breast, Cervical, and Colorectal Cancer Screening and HPV Vaccination Among Underserved Texans
This study involves a partnership between UTHealth School of Public Health and the Texas 2-1-1 service, which is a helpline connecting low-income and minority callers with a number of needed services.
- Trial name
- NCT04638010
- Testing
- Cancer control navigation (CNN), General referral (usual care)
- Where
- United States
- Volunteers
- 1,554 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Breast Cancer
Study to Compare the Diagnostic Accuracy of Nuance Full-Field Digital Mammography to Screen-Film Mammography
Evaluate the diagnostic accuracy of the Planmed Sophie Nuance Full Field Digital Mammography (FFDM) X-ray System compared to screen-film mammography (SFM) in the detection of breast cancer.
- Trial name
- NCT00942396
- Testing
- Full Field Digital Mammogram (Planmed Sophie Nuance)
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Planmed Oy
Screen Time Exposure
Mindfulness-based Intervention and Young Children's Screen Time
This research proposal aims to explore the effectiveness of the mindfulness-based intervention (MBI) on reducing young children's screen time (ST) and caring parents' psychological and social issues in Hong Kong.
- Trial name
- NCT07083661
- Testing
- Mindfulness-based intervention on parent empowerment in reducing children's screen time (MORE)
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Child Psychiatry, Adolescent Psychiatry
Translation and Validation of the "Children and Adolescent Trauma Screen" in French
Child psychotraumatism and complex psychotraumatism, mainly consecutive to child maltreatment, is a major unaddressed public health issue.
- Trial name
- French-CATS (NCT05690113)
- Testing
- CATS scale
- Where
- 6 sites in France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Lung Cancer Screening
CPRIT: Patient Adherence to Lung Cancer Screening
To understand participants' barriers to lung cancer screening and their experience with scheduling lung cancer screening.
- Trial name
- NCT06872723
- Testing
- Lung Cancer Screening
- Where
- United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Cancer
Colorectal Cancer Screening Navigator Program for Low Income and Non-English Speaking Populations
The goal of this study is to implement and in a controlled randomised trial test a program to identify and overcome barriers to CRC screening and thus improve CRC screening rates at MGH Chelsea HC.
- Trial name
- NCT00476970
- Testing
- Patient Navigation
- Where
- United States
- Volunteers
- 1,223 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Breast Cancer
System-integrated Point-of-Care Ultrasound in Breast Cancer Screening
To assess the feasibility, safety, and clinical performance of community-based breast cancer screening incorporating clinical breast exam and short-termed trained examiners performing AI-supported breast POCUS for triage in…
- Trial name
- SPRING (NCT07462351)
- Testing
- AI
- Where
- Ethiopia
- Volunteers
- 4,800 people, healthy volunteers welcome
- Sponsor
- Region Skane
Melanoma
Melanoma Simulation Model With Smartphone Devices: Training Physicians for Early Detection of Melanoma
The specific aim of this study is to determine if interactive touchscreen-based learning with deliberate practice modules can enhance the retention of life-saving medical skills when incorporated into medical training curricula.
- Trial name
- NCT01859845
- Testing
- Smartphone
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Northwestern University
ColoRectal Cancer Screening
Patient Navigation for Colorectal Cancer Screening for Patients With Mental Illness and/or Substance Use Disorder
The investigators propose to develop, implement, and evaluate a novel Colorectal (CRC) screening patient navigator program for patients with Mental Health (MH) and /or Substance Use Disorder (SUD) receiving care at Massachusetts…
- Trial name
- NCT03244787
- Testing
- patient navigation
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Down Syndrome, Chromosome Abnormalities
Down Syndrome - Comparison of Screening Methods in the 1st and 2nd Trimesters
Too much or too little genetic information (chromosome material) can cause abnormal development of the fetus or death. Each year approximately 2.5 million pregnant women are screened for Down Syndrome using invasive screening…
- Trial name
- NCT00006445
- Testing
- Ultrasound, Serum screen
- Where
- 10 sites in United States
- Volunteers
- 38,000 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Breast Cancer, Cervical Cancer
Cultivando la Salud: A Breast and Cervical Cancer Screening Promotion Program for Low-Income Puerto Rican Women
The overall goal of this education program is to increase breast and cervical cancer screening in low-income women in Puerto Rico through implementation of an evidence-based educational program that addresses both health…
- Trial name
- CLS (NCT04617236)
- Testing
- Cultivando La Salud
- Where
- Puerto Rico
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Mouth Neoplasms
Visual Oral Examination for Early Detection of Oral Cancer in High-Risk Individuals
Oral cancer (OC) is a public health problem in Brazil, with high morbidity and mortality, mainly associated with late diagnosis, which implies high-cost treatments and great social impact, with aesthetic and functional sequelae.
- Trial name
- NCT06231537
- Testing
- Visual oral examination
- Where
- Brazil
- Volunteers
- 1,152 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Breast Cancer
Testing Conversation Aid in Practice
The goal of this research study is to develop and test a website to help primary care providers (PCPs) discuss the pros and cons of mammography with women aged 75 and older and to help participants make decisions about…
- Trial name
- NCT06011434
- Testing
- Mammography Screening Conversation Aid
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Physical Activity, Sedentary Behavior
FeetEnergy Approach to Increase Physical Activity and Reduce Screen Time in Adolescents
The purpose of this study is to find out whether an Internet-supported FeetEnergy approach and two home works integrated in three health education lessons can increase adolescents' active commuting to school and leisure-time…
- Conditions
- Physical Activity, Sedentary Behavior, Active Commuting, Psychosocial Factors
- Trial name
- FeetEnergy (NCT01633918)
- Testing
- Internet-supported FeetEnergy approach, Usual health education
- Where
- 2 sites in Finland
- Volunteers
- 1,291 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Colorectal Cancer
Colorectal Cancer Screening Intervention Study
Colorectal cancer (CRC) is one of the leading causes of cancer mortality in the United States, and African Americans (AfAms) still fare worse in CRC incidence and mortality compared to European Americans (EuAms).
- Trial name
- NCT06424197
- Testing
- Racial group-targeted messages, Explicit Commitment
- Where
- United States
- Volunteers
- 799 people, healthy volunteers welcome
- Sponsor
- Oakland University
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