Clinical trials: Early Cancer Detection
Colorectal Cancer
Financial Incentives to Increase Colorectal Cancer Screening in Priority Populations
The investigators propose to build on the success of the Systems of Support to Increase Colorectal Cancer trial (SOS, R01CA121125, Green) and focus on disparity groups who are less likely to be current for colorectal cancer (CRC)…
- Trial name
- NCT03080701
- Testing
- Auto Mailing Plus Money, Auto Mailing Plus Lottery
- Where
- United States
- Volunteers
- 898 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Cervical Intraepithelial Neoplasia, Cervical Cancer
The Development of a "Mother/Child, Screen, Treat and Vaccinate Program" in Manchay and Iquitos, Peru
This project will use a community based participatory research orientation to develop a model for large scale "campaign" preventive healthcare interventions.
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, Cervical Neoplasm, Cervical Dysplasia
- Trial name
- PERCAPS (NCT01338051)
- Testing
- Gardasil
- Where
- 2 sites in Peru
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- Preventive Oncology International, Inc.
Breast Cancer
Comparison of Contrast-enhanced Spectral Mammography (CESM) to MRI in Screening High Risk Women for Breast Cancer
This research study is comparing Dual-Energy Contrast-Enhanced Spectral Mammography (CESM) to MRI as a screening tool for breast cancer.
- Trial name
- NCT02275871
- Testing
- MRI, CESM
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Deglutition Disorders, Dysphagia
Development of a Web-Based Course to Maintain Skills in Nurses Trained to Screen for Dysphagia
This research aims to facilitate the successful implementation of the new Heart and Stroke Foundation of Ontario dysphagia screening model for acute stroke patients.
- Conditions
- Deglutition Disorders, Dysphagia, Stroke
- Trial name
- NCT00570557
- Testing
- TOR-BSST© Refresher Training
- Where
- 5 sites in United States, Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Colorectal Cancer Screening
Optimization of the Bowel Preparation Regimen for the PillCam® COLON 2 Capsule Endoscopy Procedure
This study is designed to determine the optimal bowel preparation regimen for PillCam® COLON 2 Capsule Endoscopy System (CCE) procedures in average risk patients.
- Trial name
- NCT02481219
- Testing
- PillCam® COLON 2 procedure-CONTROL, Senna tablets, PEG
- Where
- 6 sites in United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Lung Cancer, Tobacco Use
A Community Health Intervention to Improve Lung Cancer Screening Uptake in Community Health Centers
Lung cancer screening (LCS) can reduce lung cancer-related mortality, but screening uptake remains low among eligible individuals.
- Trial name
- CHATS (NCT07168629)
- Testing
- Community health worker delivered outreach, shared decision-making, tobacco treatment, and navigation, Lay Navigator delivered outreach, shared decision-making, tobacco treatment, and navigation, Enhanced Usual Care
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
Lung Cancer
NovellusDx Cancer Early Detection Blood Test- Clinical Trial
NovellusDx early detection test is a simple to perform blood test, which identifies the deregulated signaling pathways within the patient tumor based on protein secretion to the blood, thus enabling early stage disease signature…
- Trial name
- NCT01883388
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fore Biotherapeutics
Heavy Smoking
Bronchoscopy Screening for High-risk Population of Lung Cancer With Severe Smoking With Negative LDCT Screen
Based on the previous work of LDCT screening, in order to improve the screening rate of central lung cancer for LDCT negative and severe smokers, the investigators plan to conduct China's first large-scale fluorescent…
- Trial name
- NCT04413669
- Testing
- white light bronchoscopy & autofluorescence bronchoscopy
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Jiayuan Sun
Mediterranean Diet, Physical Activity
24-h Movement Behaviors and Adherence to the Mediterranean Diet in Children
The purpose of this study is to determine the effects of the Archena Infancia Saludable project on adherence to MD and 24-h movement behaviors in schoolchildren
- Conditions
- Mediterranean Diet, Physical Activity, Sedentary Time, Sleep
- Trial name
- NCT05620303
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Cervical Cancer, Human Papillomavirus Infection
Prospective Evaluation of Self-Testing to Increase Screening (PRESTIS) Asian/Asian American Women Supplement
Regularly attending for Pap test cervical cancer screening in a clinic is often unfeasible and/or unacceptable to many women and persons with a cervix.
- Trial name
- NCT06577220
- Testing
- Telephone Recall, Mailed HPV Self-Sampling Kit, Patient Navigation
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Colon Cancer Screening, Colon Cancer Surveillance
Enchasing Polyp Detection: The Effect of Adding Polyp Detection Attachment Device to Computer Aid Detection System.
Despite the widespread use of colonoscopy, the ongoing challenge of potentially missing polyps remains. Previous studies have independently shown that both Endocuff, a colonoscope attachment device for polyp detection, and…
- Trial name
- NCT06116864
- Testing
- Endocuff and GI Genius, GI Genius
- Where
- United States
- Volunteers
- 1,766 people, healthy volunteers welcome
- Sponsor
- Marshall University
ESCC
Integrated Cf-miRNA and Exosomal miRNA Signature for Early Detection of Esophageal Squamous Cell Carcinoma
Esophageal squamous cell carcinoma (ESCC) remains a highly lethal cancer worldwide, largely due to late diagnosis. Current screening methods such as upper endoscopy are invasive, operator-dependent, and limited in their ability…
- Trial name
- SYNERGY (NCT07266363)
- Testing
- Small RNA sequencing of exo- and cf-miRNAs, RT-qPCR quantification of cf- and exo-miRNAs (SYNERGY assay), PCR-based validation (SYNERGY assay)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Cancer Screening, Early Detection of Cancer
Risk Reduction Program for Women Having High Risk of Breast Cancer
An intervention program involving education, guidance, counseling, case management and surveillance based on the Health Belief Model will be implemented on women with high risk of breast cancer.
- Conditions
- Cancer Screening, Early Detection of Cancer, Breast Cancer, Preventive Health Care
- Trial name
- BrCaRRP (NCT04304404)
- Testing
- Breast Cancer Risk Reduction Program (BrCaRRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Brest Cancer, Lung Cancer (NSCLC)
The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and Immune Cell Transcriptomic Profiling
The purpose of the CCANED-CIPHER study is to develop and validate an AI-based blood test for early cancer detection and to monitor treatment effectiveness in cancer patients.
- Conditions
- Brest Cancer, Lung Cancer (NSCLC), Pancreatic Cancer, Adult, Prostate Cancers
- Trial name
- CCANED-CIPHER (NCT06717295)
- Testing
- DiNanoQ: A multi-cancer early detection (MCED) blood test, DiNanoTrack: Therapeutic Response Monitoring Blood Test
- Where
- 4 sites in Argentina, Nigeria and 1 more
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Javier Toledo
Invasive Cancer, Ductal Carcinoma in Situ
The Mammography and Ultrasonography STudy for Breast Cancer Screening Effectiveness
Mammography screening has limited performance in young women or women with dense breasts although it is the only proven method for breast cancer screening that reduces the mortality.
- Trial name
- MUST-BE (NCT02909426)
- Testing
- Ultrasonography, Digital mammography
- Where
- South Korea
- Volunteers
- 11,880 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Malnutrition
Comparing Performance of Simplified Mid-Upper Arm Circumference Devices ("Click-MUACs") to Detect Acute Malnutrition
The Click-Mid-Upper Arm Circumference study aims to describe and compare the performance of a set of three simplified mid-upper arm circumference classification devices ("Click-MUAC") for use by mothers and caregivers to screen…
- Trial name
- NCT02833740
- Testing
- Click-MUAC prototype & regular MUAC tape
- Where
- Kenya
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Action Contre la Faim
Breast Cancer
A Mammography FastTrack Program in Increasing the Number of Women Undergoing Breast Cancer Screening
RATIONALE: Screening may help doctors find breast cancer cells early and plan better treatment for breast cancer. The Mammography FastTrack program may be effective in increasing the number of patients who undergo mammography.
- Trial name
- NCT00462891
- Testing
- IT System
- Where
- United States
- Volunteers
- 6,730 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cervical Cancer
Pilot Study of a Mobile Health Approach to Reduce Barriers to Cervical Cancer Screening in Tanzania
The purpose of this study is to determine whether motivational text messages and/or travel vouchers are effective in increasing cervical cancer screening rates in urban and rural regions of Northern Tanzania.
- Trial name
- KCCPAS (NCT02680613)
- Testing
- Motivational SMS, Travel Voucher
- Where
- Tanzania
- Volunteers
- 851 people, healthy volunteers welcome
- Sponsor
- Queen's University
Human Papilloma Virus, Breast Cancer
Mobile App-Supported HPV and Breast Cancer Awareness Program
The goal of this study is to learn about the impact of a mobile application-supported education program on women's HPV literacy and their beliefs regarding breast cancer screening.
- Conditions
- Human Papilloma Virus, Breast Cancer, Women
- Trial name
- NCT07471113
- Testing
- mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Prostate Cancer
Evaluating the Impact of Evidence-based Information About PSA Testing on Prostate Cancer Screening Decisions
Patient decision aids are tools that help guide individuals through a healthcare-related decision making process. They help users combine evidence-based information and recommendations by a health care provider with their…
- Trial name
- NCT03477591
- Testing
- Evidence-based information, Patient Decision Aid
- Where
- Canada
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- McMaster University
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