Clinical trials: Early Cancer Detection
Cervical Carcinoma
Cervical Cancer Screening Intervention Among Korean American Women
This is a randomized trial to evaluate the effects of a community-based intervention on increasing cervical cancer screening rates in underserved Korean American women.
- Trial name
- NCT02594826
- Testing
- Culturally appropriate intervention, General health education control
- Where
- United States
- Volunteers
- 744 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
CRC Screening, Compliance, Patient
Lay Tel Compliance Study
This is a randomized controlled study to compare the effectiveness of interactive telephone reminders by a layperson on enhancing compliance with CRC screening by FOBT, when compared with usual care (i.e. no intervention).
- Trial name
- NCT03197116
- Testing
- Telephone reminder, No other
- Where
- Hong Kong
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Cancer
Establishment and Clinical Validation of New Technologies for Accurate Screening of Colorectal Cancer Based on Multi-omics
Background: The current screening techniques for colorectal cancer include colonoscopy, fecal occult blood, and high-risk factor questionnaires.
- Trial name
- NCT04913233
- Where
- 3 sites in China
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cancer
Does Screening With the Galleri Test in the NHS Reduce the Likelihood of a Late-stage Cancer Diagnosis in an Asymptomatic Population? A Randomised Clinical Trial
The Galleri test is a new test that looks for potential signs of cancer in a blood sample. The test can find many different types of cancer but cannot find all cancers.
- Trial name
- NHS-Galleri (NCT05611632)
- Testing
- Multi-cancer early detection test (Galleri test)
- Where
- United Kingdom
- Volunteers
- 142,318 people, healthy volunteers welcome
- Sponsor
- GRAIL, Inc.
Lung Cancer, Pulmonary Nodule
Improving Detection of Early Lung Cancer in a Diverse Population (IDEAL) Study
The goal of this trial is to (a) identify people at high risk of lung cancer who would benefit from LDCT screening but are currently ineligible based on current lung cancer screening criteria (b) provide the framework to manage…
- Trial name
- IDEAL (NCT06628102)
- Testing
- Chest CT Scan
- Where
- Canada
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Breast Cancer, Mammary Cancer
The Effect of a Patient Decision Aids for Breast Cancer Screening
Breast cancer is one of the most common cancers in Chile. National efforts focus on early detection, offering universal access to breast cancer screening through mammography to women at risk age.
- Conditions
- Breast Cancer, Mammary Cancer, Breast Tumor, Mammary Tumor
- Trial name
- NCT04948983
- Testing
- Decision aid (DA) for breast cancer screening, Standarised information for breast cancer screening
- Where
- Chile
- Volunteers
- 3,269 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Breast Cancer
Effect of Audiovisual Education on Breast Cancer
This study was conducted as a double-blind randomised controlled trial to determine the effect of education using audio-visual methods and simulation techniques on breast cancer screening and breast cancer fears in illiterate…
- Trial name
- NCT06898229
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Cervical Carcinoma, Human Papillomavirus-Related Carcinoma
Prevention and Early Detection of Cervical Cancer Through Self-Administered Screening
This study examines prevention and early detection of cervical cancer through self-administration screening of patients in Western Uganda.
- Trial name
- NCT04927650
- Testing
- HPV testing, Questionnaire Administration
- Where
- Uganda
- Volunteers
- 2,556 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Adverse Mental/Physical Effects of Low Dose S. Tortuosum.
Safety Study of the Effect of Scelectium Tortuosum (as Zembrin®)in Aged Normals
Phosphodiesterase is a candidate for the Rx \& prevention of cognitive and psychotic disorders. Since caffeine targets primarily PDE4(Phosphodiesterase subtype 4), caffeine analogs have been developed to mimic the actions of…
- Trial name
- NCT01805518
- Testing
- Scelectium Tortuosum
- Where
- Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Woodbury, Michel, M.D.
Breast Cancer
Cone Beam Breast CT for Breast Cancer Screening
Up to one thousand and twenty-eight (1028) patients from screening and diagnostic population will be enrolled and consented to participate in the study to create an enriched data set.
- Trial name
- NCT05036096
- Testing
- CBBCT Imaging, Digital Mammography
- Where
- 4 sites in United States
- Volunteers
- 1,024 people, healthy volunteers welcome
- Sponsor
- Koning Corporation
Breast Cancer, Screening
Artificial Intelligence Assisted Breast Ultrasound in Breast Cancer Screening
AIBU is a randomized, open-label study assessing the effectiveness of an articificial intelligence-assisted breast ultrasound breast cancer screening strategy compared to standard screening (according to the current local…
- Trial name
- AIBU (NCT06521788)
- Testing
- AI-assisted breast ultrasound, Routine breast ultrasound
- Where
- 3 sites in China
- Volunteers
- 21,790 people, healthy volunteers welcome
- Sponsor
- Fudan University
Lung Cancer, Smoking Cessation
PCORI-CER-1306-03385 Informed Decisions About Lung Cancer Screening
Educational research study where goal is to test educational materials that help people make informed decisions about lung cancer screening.
- Conditions
- Lung Cancer, Smoking Cessation, Tobacco Use Cessation
- Trial name
- NCT02286713
- Testing
- Patient Decision Aid, Standard Educational Information, Follow-Up Assessments: Questionnaires
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cervical Cancer
Increasing Cervical Cancer Screening Uptake Among Emergency Department Patients
Invasive cervical cancer is preventable with adequate screening but screening rates are considerably below national goals. Emergency departments care for a disproportionate number of women who are not up to date with recommended…
- Trial name
- NCT04374760
- Testing
- SMS-intervention
- Where
- 2 sites in United States
- Volunteers
- 1,116 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Virtual Reality
Virtual Reality Compared to Screen Based Engagement on Mood
Depression has a lifetime prevalence rate of 20.6% and has one of the highest prevalence rates of mental health disorders. Major depressive disorder can lead to higher costs of living for individuals as well as a larger economic…
- Trial name
- NCT05249582
- Testing
- Virtual Reality, Television Condition
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Palo Alto University
Trisomy 21 and Other Fetal Aneuploidy
Automated Screen for Fetal Aneuploidy
The purpose of this study is to develop and evaluate a blood test and automated microfluidic test platform for the prenatal screening of fetal aneuploidy.
- Trial name
- FAST1 (NCT03635359)
- Testing
- blood test
- Where
- 6 sites in Australia, Belgium and 4 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- BioCeryx
Childhood Obesity
A School-based to Prevent Obesity Among Children Aged 4-7 Years- A Feasibility Quasi-Experimental Trial in Karachi, Pakistan
Obesity is a chronic, complex disease that can harm one's health; obesity is characterized by excessive fat deposits. In 2022, 37 million children under the age of 5 were overweight.
- Trial name
- NCT07521579
- Testing
- Lifestyle Management
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Smoking, Tobacco
Assessing the Integration of Tobacco Cessation Treatment Into Lung Cancer Screening (LCS)
This randomized controlled trial seeks to evaluate the effectiveness of alternative strategies to integrate smoking cessation interventions into the delivery of low-dose CT (LDCT) lung cancer screening.
- Trial name
- ScreenASSIST (NCT03611881)
- Testing
- Counseling, Nicotine patch, Community Resource
- Where
- 6 sites in United States
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Lung Cancer, Small Cell Lung Cancer
A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in China
The primary objective of this study is to assess the safety and effectiveness of Human Multigene Methylation Detection Kit (Fluorescent PCR Method) for help diagnose lung cancer by comparing with clinical standard method…
- Conditions
- Lung Cancer, Small Cell Lung Cancer, Non-Small Cell Lung Cancer, Squamous Cell Carcinoma
- Trial name
- NCT05337163
- Testing
- Diagnostic Test: Sputum DNA methylation analysis, chest CT or pathological examination
- Where
- China
- Volunteers
- 1,564 people, healthy volunteers welcome
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Lung Cancer
Community Support Program for Lung Cancer Screening Volume II
This is a West Philadelphia based community project to improve adherence to lung cancer screening. The overall objective of this project is to demonstrate the impact of a community support program (CSP) on improve adherence to…
- Trial name
- LCS II (NCT06628167)
- Testing
- Transportation, Scheduling
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Breast Cancer, Bowel Cancer
Improving Muslim Women's Uptake of Cancer Screening (IMCAN)
The goal of this non-randomised trial is to test how a workshop that includes religiously-tailored messages can help increase the uptake of breast, colorectal and cervical cancer screening among Muslim women in North East England…
- Conditions
- Breast Cancer, Bowel Cancer, Cervical Cancer
- Trial name
- IMCAN (NCT06106165)
- Testing
- In-person peer-led faith-based intervention to encourage breast, bowel, and cervical screening uptake among Muslim women, Online In-person peer-led faith-based intervention to encourage breast, bowel, and cervical screening uptake among Muslim women
- Where
- 2 sites in United Kingdom
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Sunderland
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