Clinical trials: Early Cancer Detection
Breast Cancer Screening, Cervical Cancer Screening
Community Gateway to Health Study
The goal of this study is to evaluate the impact of a multi-level intervention on cancer prevention and social determinants of health outcomes.
- Conditions
- Breast Cancer Screening, Cervical Cancer Screening, Colon Cancer Screening, Tobacco Cessation
- Trial name
- NCT07592793
- Testing
- Tools and Training for Cancer Control, Enhancing Social Capital and Civic Engagement
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Breast Cancer
Personalized Breast Cancer Screening
The purpose of the study is to measure short-term safety and efficacy of personalized vs. standard mammography screening among 50-67-year aged women.
- Trial name
- PRSONAL (NCT06060938)
- Testing
- Risk stratified arm, Control arm
- Where
- Denmark
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Colorectal Cancer
Early Detection and Risk Stratification of Colorectal Cancer Based on miRNA Platform
This is a prospective, observational cohort study to establish the minimal residual disease (MRD) model for predicting relapse risk and identifying disease recurrence in patients with colorectal adenocarcinoma based on the miRNA…
- Trial name
- NCT06351384
- Testing
- miRNA detection test
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Pancreatic Ductal Adenocarcinoma
Early Detection of Pancreatic Adenocarcinoma (PDAC) Using a Panel of Biomarkers
Urine and blood samples are being collected from patients with and without diseases of the pancreas. These samples will be tested with the aim of developing an accurate way of diagnosing diseases of the pancreas using the results.
- Trial name
- UroPanc (NCT04449406)
- Where
- 4 sites in United Kingdom
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Cervical Cancer
Using CHWs and HPV Home Tests to Increase Cervical Cancer Screening in Minority Populations
Caribbean immigrants (both Hispanics and Blacks from Haiti) are less likely to be screened for cervical cancer than the general population.
- Trial name
- SUCCESS (NCT02121548)
- Testing
- CHW Outreach and HPV Self-sampling, CHW Outreach
- Where
- United States
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- University of Miami
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Colorectal Cancer, Colorectal Adenoma
Fecal DNA Methylation Test for Colorectal Cancer Screening
This is an observational, prospective study using fecal DNA methylation test to define the risk of suffering from advanced adenoma or colorectal cancer (CRC) compared to colonoscopy and fecal immunochemical test (FIT).
- Trial name
- NCT04823793
- Testing
- Stool DNA methylation detection
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Lung Cancer
Population Health Management -Increase Lung Cancer Screening in Community Health Centers (LungSMART)
The long-term goal of Lung Sequential Multiple Assignment Randomized Trial (LungSMART) Utah is to increase the reach of Low-Dose Computed Tomography (LDCT) screening for lung cancer (hereafter referred to as Lung Cancer Screening…
- Trial name
- LungSMART (NCT07599943)
- Testing
- Text Messages (TM+), Chatbot (CA), Video (VID)
- Where
- United States
- Volunteers
- 18,894 people, healthy volunteers welcome
- Sponsor
- University of Utah
Breast Cancer Detection, Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Validation of the Oncoliq Test for the Early Detection of Breast Cancer.
Cancer continues to be one of the most significant public health issues worldwide. Thanks to early detection, the mortality rate of certain types of cancer has decreased significantly.
- Conditions
- Breast Cancer Detection, Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer Female, Breast Cancer - Ductal Carcinoma in Situ (DCIS)
- Trial name
- NCT07331506
- Testing
- Peripheral blood draw
- Where
- Argentina
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oncoliq US Inc
Colorectal Cancer
PRESEPT Study: Evaluation of SEPT9 Biomarker Performance for Colorectal Cancer Screening
The purpose of this study is to collect blood specimens and clinical data from screening guideline eligible individuals designated by their physician to receive a screening colonoscopy, and to evaluate the performance of a…
- Trial name
- PRESEPT (NCT00855348)
- Testing
- All eligible subjects will provide blood for SEPT9 biomarker testing
- Where
- 23 sites in United States, Germany
- Volunteers
- 7,929 people, healthy volunteers welcome
- Sponsor
- Epigenomics, Inc
Lung Cancer, Chronic Obstructive Airway Disease
Early Detection of Lung Tumors by Sniffer Dogs - Evaluation of Sensitivity and Specificity
Some groups reported that sniffer dogs can be applied to detect lung cancer in the exhaled breath of patients. Therefore, breath samples (BS) of patients are collected.
- Trial name
- NCT01141842
- Testing
- exhalation analysis of breath sample
- Where
- 2 sites in Germany
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Schillerhoehe Hospital
Cervical Cancer Screening
Effectiveness of an eHealth Intervention for Uptake of Cervical Cancer Screening in Hispanic Women
This study will test the effectiveness of an eHealth promotora (lay health advisor) outreach strategy to increase cervical cancer screening in Hispanic women.
- Trial name
- NCT06741241
- Testing
- eHealth Promotora, eHealth Healthy Nutrition
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Florida A&M University
Cervical Cancer, Cervical Intraepithelial Neoplasia
PRIORITY Study in Cervical Cancer
The PRIORITY study is a prospective, multicenter observational study designed to evaluate an integrated diagnostic model combining extended molecular self-sampling and digital colposcopy supported by telemedicine for the…
- Conditions
- Cervical Cancer, Cervical Intraepithelial Neoplasia, HPV Infection
- Trial name
- PRIORITY (NCT07593066)
- Where
- 8 sites in Chile
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Lung Neoplasms
Development and Feasibility Testing of a Lung Cancer Screening Decision Aid
This study evaluates the feasibility and acceptability of LuCaS Choices, a web-based decision aid designed to facilitate informed decision making about participation in lung cancer screening among individuals at high risk of lung…
- Trial name
- LuCaS-DA (NCT02790866)
- Testing
- LuCaS Decision Aid, NCI Website
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jamie Studts
Cervical Carcinoma
A Community Based Intervention to Improve Cervical Cancer Screening Among Women in the Hispanic and East African Immigrant Community
This clinical trial studies whether a community based intervention improves cervical cancer screening (CCS) among women in the Hispanic and East African immigrant community.
- Trial name
- NCT07890402
- Testing
- HPV Self-Collection, Informational Intervention, Interview
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colorectal Cancer Screening
CRC Screening in Unscreened Individuals 45-54
The goal of this observational study is to understand the barriers and facilitators to completing colorectal cancer screening from the patient and community health center staff perspective.
- Trial name
- NCT06757192
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy Lifestyle, Education
Effects of Education After Colorectal Cancer Screening
The aim of this study is to examine the effect of the education given to individuals undergoing colorectal cancer screening on their attitudes, beliefs and healthy lifestyle behaviors.
- Trial name
- NCT06311565
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Cervical Cancer Screening
Community-based Intervention for Cervical Cancer Screening Uptake in Nepal
This study aims to evaluate the effect of a Female Community Health Volunteer (FCHV) led community-based educational intervention through home visits increasing cervical cancer screening uptake.
- Trial name
- COBIN-C (NCT03808064)
- Testing
- FCHV home visit
- Where
- Nepal
- Volunteers
- 690 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cervical Cancer
Acceptability of HPV-self Sampling
This trial aimed at evaluating the acceptability of HPV self-sampling among french women eligible for cervical cancer screening (25 - 65 years old) in the region of Occitanie, in the south of France.
- Trial name
- NCT03137563
- Testing
- questionnaire
- Where
- France
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Breast Neoplasms, Uterine Cervical Neoplasms
Early Detection of Cancers in Low Resource Countries
The purpose of this study is to implement a community-based combined program for early detection of breast, cervical, ovarian and endometrial cancer in low-resource countries delivered through a free standing or a mobile Well…
- Conditions
- Breast Neoplasms, Uterine Cervical Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms
- Trial name
- NCT01178736
- Testing
- Breast Cancer Screening and Diagnosis, Cervical Cancer Screening and Diagnosis, Ovarian Cancer Screening and Diagnosis
- Where
- 3 sites in Brazil, Cambodia and 1 more
- Volunteers
- 36,000 people, healthy volunteers welcome
- Sponsor
- Woman's Cancer Foundation
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