Clinical trials: Early Cancer Detection
Cervical Cancer, Stigma
Effectiveness of a Cervical Cancer Stigma Reduction Intervention Program on Cancer Stigma Score and Cervical Cancer Screening Uptake in Nepal
It is an interventional study to assess the effectiveness of the cervical cancer stigma reduction intervention on cancer stigma score and cervical cancer screening uptake in Nepal
- Conditions
- Cervical Cancer, Stigma, Screening
- Trial name
- NCT05489978
- Testing
- "Cervical Cancer Stigma Reduction Intervention"
- Where
- Nepal
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Kathmandu University School of Medical Sciences
Frailty, Intrinsic Capacity
Implementation of Decade of Healthy Ageing Action Plan to Screen and Prevent Decline in Intrinsic Capacity in Elders (SPICE) Through Multisectoral Collaboration in Singapore
This study evaluates the implementation of a structured community-based pathway to screen, risk stratify, and prevent decline in intrinsic capacity (IC) among adults aged 60 years and above in Singapore.
- Conditions
- Frailty, Intrinsic Capacity, Lifestyle
- Trial name
- SPICE (NCT07525583)
- Testing
- ICOPE-Based Digital Intrinsic Capacity Monitoring and Triggered Follow-up (SPICE Pathway)
- Where
- Singapore
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Non Small Cell Lung Cancer
Blood Testing to Detect Cancer Recurrence in Patients With Early-Stage Non-Small Cell Lung Cancer
This observational study will evaluate whether a blood test can detect the return of non-small cell lung cancer at least three months before it is identified on routine imaging.
- Trial name
- NCT07854769
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Colorectal Cancer
Low-Literacy Physician-Patient Intervention Promoting Colorectal Cancer Screening
The purpose of this study is to evaluate the effectiveness of a low literacy, physician and patient-directed intervention to promote colorectal cancer (CRC) screening among the medically underserved.
- Trial name
- NCT01103479
- Testing
- Physician Intervention, Physician and Patient Intervention
- Where
- 2 sites in United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Northwestern University
CBD, Chronic Pain
Cannabidiol, Morphine, Pain
The purpose of the proposed study is to investigate the interaction of cannabidiol (CBD) and morphine effects on pain sensitivity.
- Trial name
- CMP (NCT04030442)
- Testing
- Immediate-release Oral Morphine Sulfate Tablets, Thermal and Pressure Nociceptive Sensitivity
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Cervix Cancer, Cervical Intraepithelial Neoplasia
Cervical Cancer Screening Based on First-void Urine Self-sampling to Reach un(Der)-Screened Women: ScreenUrSelf Trial
The goal of the ScreenUrSelf trial is to increase cervical cancer screening attendance and compliance to follow-up by offering a first-void urine self-sampling alternative to women who are currently not participating in the…
- Conditions
- Cervix Cancer, Cervical Intraepithelial Neoplasia, Human Papilloma Virus, HPV-Related Cervical Carcinoma
- Trial name
- ScreenUrSelf (NCT05996783)
- Testing
- Colli-Pee Small Volumes, Evalyn Brush
- Where
- Belgium
- Volunteers
- 48,000 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Non-small Cell Lung Cancer, Lung Neoplasms
International Lung Screen Trial (ILST)
People who may be at increased risk of lung cancer due to age and smoking history will be invited to participate in this international study to determine the best way of using computed tomography (CT) of the chest to screen for…
- Conditions
- Non-small Cell Lung Cancer, Lung Neoplasms, Respiratory Tract Neoplasms, Thoracic Neoplasms
- Trial name
- ILST (NCT02871856)
- Testing
- Low dose CT
- Where
- 6 sites in Australia, Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Cervical Cancer Screening
Emergency Room HPV Self-Sampling Study (ACT NOW)
The goal of this study is to develop and evaluate an evidence-based public health intervention using HPV self-sampling approach in an opportunistic setting to increase cervical cancer screening among screening non-attendees…
- Trial name
- ACT NOW (NCT06178549)
- Testing
- HPV Self-Sampling
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Lung Cancer
Population Health Management -Increase Lung Cancer Screening in Community Health Centers (LungSMART)
The long-term goal of Lung Sequential Multiple Assignment Randomized Trial (LungSMART) Utah is to increase the reach of Low-Dose Computed Tomography (LDCT) screening for lung cancer (hereafter referred to as Lung Cancer Screening…
- Trial name
- LungSMART (NCT07599943)
- Testing
- Text Messages (TM+), Chatbot (CA), Video (VID)
- Where
- United States
- Volunteers
- 18,894 people, healthy volunteers welcome
- Sponsor
- University of Utah
Breast Cancer Detection, Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Validation of the Oncoliq Test for the Early Detection of Breast Cancer.
Cancer continues to be one of the most significant public health issues worldwide. Thanks to early detection, the mortality rate of certain types of cancer has decreased significantly.
- Conditions
- Breast Cancer Detection, Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer Female, Breast Cancer - Ductal Carcinoma in Situ (DCIS)
- Trial name
- NCT07331506
- Testing
- Peripheral blood draw
- Where
- Argentina
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oncoliq US Inc
Ovarian Diseases, Ovarian Neoplasms
Cancer Screening Program for Women at High Risk for Developing Ovarian Cancer
The main purpose of this program is to see whether periodically measuring CA-125 (tumor marker) levels in the blood and undergoing transvaginal ultrasounds over time will be effective in the early detection of ovarian cancer.
- Trial name
- OCEDP (NCT01292733)
- Testing
- Laboratory Tumor Marker Analysis, Transvaginal Ultrasound, Health Status Questionnaire
- Where
- United States
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- Swedish Medical Center
Colorectal Cancer
Lifestyle Intervention Among Participants of the French Colorectal Cancer Screening Program
The investigators propose a randomized controlled trial to develop and evaluate the impact of promoting advice on diet and lifestyle recommendations for cancer prevention at colorectal cancer screening among individuals who may…
- Trial name
- LIFE-SCREEN (NCT04257526)
- Testing
- Diet and lifestyle advice following a positive FIT test and diagnostic colonoscopy.
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Colorectal Cancer
The PRIME-CRC Trial to Promote CRC Screening in Rural Communities
The investigators will expand an existing, patient-centered, health literacy strategy to promote longer-term adherence to colorectal cancer (CRC) screening in resource-limited, rural health clinics via colonoscopy or annual fecal…
- Trial name
- NCT04313114
- Testing
- health literacy appropriate education and demonstration, shared decision making, automated call reminders or automated texts
- Where
- 3 sites in United States
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Breast Cancer
Tomosynthesis as Primary Test for Breast Cancer Screening
Randomized trial comparing tomosynthesis plus synthetic 2D Mammography vs Digital Mammography in respect to incidence of advanced cancers (interval and following round) and interval cancers.
- Trial name
- MAITA (NCT04461808)
- Testing
- tomosynthesis + synthetic 2D, digital mammography
- Where
- 4 sites in Italy
- Volunteers
- 10,156 people, healthy volunteers welcome
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Lung Cancer
Centralized Screening Unit (CSU) at Montefiore-Einstein
This study proposes to increase Lung-cancer screening (LCS) in the Bronx, New York. Despite strong evidence that Lung-cancer screening (LCS) can reduce Lung cancer (LCa) deaths, low-dose computed tomography (LDCT) referral rates…
- Trial name
- NCT06284408
- Testing
- Centralized Screening Unit Implementation
- Where
- United States
- Volunteers
- 9,460 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Human Papillomavirus, Uterine Cervical Neoplasms
An HPV Vaccine Provider Intervention in Safety Net Clinics
The purpose of this study is to develop, deliver and evaluate a provider intervention for mothers and their children to encourage receipt of the human papillomavirus (HPV) vaccine in the children and appropriate cervical cancer…
- Trial name
- NCT02808832
- Testing
- Educational materials
- Where
- United States
- Volunteers
- 806 people, healthy volunteers welcome
- Sponsor
- Meharry Medical College
Colorectal Cancer
Using Multimedia Approaches to Communicate Probabilities in Patient Decision Aids for Low-Literacy Populations: Randomized Trial
The goal of this research study is to compare how people who are 45-75 years old respond to 3 different versions of a program about screening tests for colorectal cancer.
- Trial name
- NCT02151032
- Testing
- Booklet, Audio CD, Video with Non-Moving Images
- Where
- 4 sites in United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Endometrial Carcinoma
Development of a New Early Detection Test to Reduce Racial Disparities in Endometrial Cancer (EC) Death Rates
This phase I trial investigates the development of a new early detection test to reduce racial disparities in endometrial cancer death rates.
- Trial name
- NCT04474184
- Testing
- Biospecimen Collection, Focus Group, Survey Administration
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Helicobacter Pylori Infection
A "Screen and Treat" Helicobacter Pylori Eradication Trial in Adolescents in Three Regions of Chile
Gastric cancer remains a global health problem, and Chile has one of the highest GC mortality rates in the region. Helicobacter pylori (H.
- Trial name
- NCT05926804
- Testing
- Lansoprazole, Amoxicillin, Clarithromycin
- Where
- 3 sites in Chile
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Miguel O'Ryan Gallardo
Screen-use Reduction + Sleep Extension, Free-living
Personalising Children's Screen Use Reduction for Better Sleep, Mental, and Brain Health
In Singapore, 64.4% of school-age children sleep less than the minimum recommended duration of 9 hours on school nights, thus risking poor mental, cognitive, and brain health.
- Trial name
- NCT05956392
- Testing
- Screen-use reduction + Sleep extension
- Where
- Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
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