Clinical trials: Early Childhood
Early Childhood Caries
Silver Diamine Fluoride(SDF) Versus SDF Combined With Sodium Fluoride Varnish in the Arrest of Early Childhood Caries
Early childhood caries (ECC) is the most common chronic childhood disease worldwide. Early restorative intervention may treat the disease but this is often difficult especially with uncooperative children so it may be left…
- Trial name
- NCT05642494
- Testing
- SDF, NaF
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Alexandria University
Early Education, Early Childhood Development
Kenya Preschool Study
This research project aims to design and evaluate an innovative model for childcare provision in rural Kenya that emphasizes child development and economic participation for women in a cost-effective manner.
- Trial name
- NCT07506603
- Testing
- PP1
- Where
- Kenya
- Volunteers
- 2,017 people, healthy volunteers welcome
- Sponsor
- Yale University
Dental Caries
Perception of Children With Visible Untreated and Treated Caries
In Germany about 5 to 20% of children suffer from early childhood caries (ECC). Preceding results of eye-tracking-studies on the perception of patients with unilateral cleft and patients with severe orthognathic malocclusion let…
- Trial name
- ECC-ET (NCT02899273)
- Where
- 2 sites in Germany
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Göttingen
Autism Spectrum Disorder, Developmental Disorder
Children's Autism Metabolome Project
Development and Clinical Evaluation of the Stemina Metabolic Biomarker-Based Test to Diagnose Autism Spectrum Disorder in Early Childhood.
- Trial name
- CAMP-01 (NCT02548442)
- Where
- 8 sites in United States
- Volunteers
- 1,102 people, healthy volunteers welcome
- Sponsor
- Stemina Biomarker Discovery, Inc.
Obesity, Growth
Prevention of Overweight in Infancy
Obesity is one of the biggest threats to health in the 21st century. Rapid weight gain in the first year of life tends to lead to overweight in children, which in turn leads to overweight in adults.
- Conditions
- Obesity, Growth, Sleep
- Trial name
- POInz (NCT00892983)
- Testing
- FAB, Sleep
- Where
- New Zealand
- Volunteers
- 802 people, healthy volunteers welcome
- Sponsor
- University of Otago
Solid Tumor, Childhood
Multicenter, Prospective Observational Study for Early Diagnosis, and Development of Follow-up Protocol and Hearing Rehabilitation Program for Ototoxic Hearing Loss After Chemotherapy for Pediatric Solid Cancer
More than half of all pediatric cancer in Korea are solid cancer. For the treatment of solid cancer, multidisciplinary methods such as surgery, chemotherapy, and radiation therapy are applied, and with the development of the…
- Trial name
- NCT05633719
- Testing
- Chemotherapy involving cisplatin or carboplatin
- Volunteers
- 300 people
- Sponsor
- Seoul National University Hospital
Child Development
Caregiver Adverse Childhood Experiences (ACEs) in Pediatric Primary Care
This longitudinal study will evaluate if increased caregiver awareness of their own ACEs through provider-led discussions will lead to improved child health via fewer emergency department, urgent care visits and missed primary…
- Trial name
- NCT05013138
- Testing
- Training for ACEs and study procedures, Training on study procedures
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- Emory University
Maltreatment
Reduce Childhood Maltreatment and Promote Development
Background (brief): 1. Burden: The uniqueness of each child is tremendously influenced by interaction between nature and nurture during critical period of brain development that promotes foundation of brain architecture through…
- Trial name
- NCT03031236
- Testing
- Psychosocial stimulation, Cognitive behavioral therapy and positive parenting practice
- Where
- Bangladesh
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Development, Child, Mindfulness
Social Emotional and Ethical Development (SEED) Video Curriculum
The objectives of the present study are to(1)By implementing the SEED Program and using videos as an intervention, the research aims to enhance these critical skills in young children.(2)The study will be the first of its kind to…
- Trial name
- NCT06210932
- Testing
- Social, Emotional, and Ethical Development (SEED) curriculum videos
- Where
- Hong Kong
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
GDM
Healthy Habits During and After Gestational Diabetes
Gestational diabetes mellitus (GDM) is associated with an increased risk of childhood obesity and other adverse health outcomes.
- Trial name
- VALID III (NCT07717515)
- Testing
- Hybrid intervention, Standard Care with Passive Web Access
- Where
- Vietnam
- Volunteers
- 2,546 people
- Sponsor
- Thai Binh University of Medicine and Pharmacy
Feeding Difficulties, Feeding Problems
Long-Term Effect of Online Occupational Therapy-Based Parent Training on Feeding Problems in Infants
This study type is a clinical trial (randomized controlled longitudinal study). The primary purpose is to determine whether an online occupational therapy-based parent training program can prevent or reduce feeding problems…
- Conditions
- Feeding Difficulties, Feeding Problems, Food Neophobia
- Trial name
- NCT07050927
- Testing
- Online occupational therapy group training
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Disruptive Behavior Disorder
Strongest Families Finland Canada: Family-based Prevention and Treatment Program of Early Childhood Disruptive Behavior
The goal of the Strongest Families Finland Canada project is to help parents develop skills to strengthen their families and reduce disruptive behavior in their 4 year old children.
- Trial name
- Fin-Can (NCT01750996)
- Testing
- Strongest Families
- Where
- Finland
- Volunteers
- 464 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Obesity, Childhood, Cardiovascular Diseases
Paediatric Obesity and Cardiovascular Dysfunction
Background Childhood obesity has been related to an impaired cardiovascular structure and function. Aims of this study will be to evaluate early cardiovascular abnormalities in a large population of obese children and adolescents…
- Trial name
- NCT03169257
- Testing
- diet plus physical activity
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Early Childhood Professional Development
Professional Development Tools to Improve the Quality of Infant and Toddler Care
Mathematica Policy Research, funded by OPRE, ACF, DHHS, will conduct a field test of We Grow Together: The Q-CCIIT Professional Development System.
- Trial name
- Q-CCIIT PD (NCT03433872)
- Testing
- We Grow Together: The Q-CCIIT Professional Development System
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Mathematica Policy Research, Inc.
Bottle Feeding, Dental Caries in Children
Controlling ECC and Terminating Bottle-feeding Habits Among Toddlers Using a Modified Oral Care Package
This study will evaluate the effectiveness of oral health promotion in the prevention of ECC (early childhood caries) in bottle-fed children.
- Trial name
- NCT04440137
- Testing
- Bottle-feeding cessation program
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Behavior Problems in Early Childhood
Pedagogues Promoting Positive Parenting in a Home-visiting Program in At-risk Families: A RCT of VIPP-SD
Supportive parenting is a strong predictor of positive outcomes for children, and harsh parenting is a risk factor for child development, especially for the child developing externalizing problems (overactive, oppositional, and…
- Trial name
- NCT04805918
- Testing
- VIPP-SD
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- University of Copenhagen
Obesity, Infant Obesity
Preventing Early Childhood Obesity, Part 2: Family Spirit Nurture, Prenatal - 18 Months
This study aims to assess the impact of a home-visiting program, called "Family Spirit Nurture" (FSN), on reducing early childhood obesity in American Indian (AI) children.
- Conditions
- Obesity, Infant Obesity, Mother-Child Relations, Dietary Habits
- Trial name
- NCT03334266
- Testing
- Family Spirit Nurture (FSN), Injury Prevention Education (IPE), Optimized Standard Care (OSC)
- Where
- 3 sites in United States
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Early Childhood Caries (ECC)
Zirconia Crowns Versus Extraction of Primary Anterior Teeth
Severely mutilated anterior primary teeth in preschool children are frequently managed by extraction. However, premature loss of anterior primary teeth has been associated with adverse functional, developmental and psychosocial…
- Trial name
- NCT07719478
- Testing
- Zirconia Crown, Extraction
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Passant Nagy
Child Abuse
iLook Out for Child Abuse: An Innovative Learning Module for Childcare Providers
This five-year study aims to improve childcare provider (CCP) reporting of suspected child abuse by means of an online learning module, iLook Out for Child Abuse.
- Trial name
- iLookOut (NCT03185728)
- Testing
- iLook Out for Child Abuse
- Where
- United States
- Volunteers
- 2,059 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Major Depressive Disorder
Depression, Epinephrine, and Platelet Function
Men and women who have suffered sexual and/or physical abuse before the age of 12 are at increased risk for anxiety and mood disorders, other serious psychiatric disorders, and likely medical illnesses.
- Trial name
- NCT00166114
- Testing
- Escitalopram, Desipramine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emory University