Clinical trials: Early Childhood
Fundamental Motor Skills, Physical Activity
A Movement and Music Programme in Early Childhood Education and Care (The MoviMusi Study Protocol)
The early childhood education and care (ECEC) environment is an important setting for providing children with daily opportunities for movement and music, supporting holistic child development in the early years.
- Conditions
- Fundamental Motor Skills, Physical Activity, Music Intervention
- Trial name
- MOVIMUSI (NCT06381687)
- Testing
- A multi-component, multi-level programme (MoviMusi)
- Where
- Spain
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Childhood Cancer Survivors
Pilot Study of Perindopril in Childhood Cancer Survivors
The purpose of this study is to evaluate the feasibility of conducting a medical intervention trial in childhood cancer survivors with early echocardiographic evidence of cardiac remodeling.
- Trial name
- NCT01948232
- Testing
- Perindopril
- Where
- Canada
- Sponsor
- The Hospital for Sick Children
Child Development
External Evaluation of the Neurological and Psycho-affective Early Childhood Development Program of the Mexican NGO Un Kilo de Ayuda
Investing in early childhood development is one of the best cost-effective investments a country can make to boost long term economic growth, promote peaceful and sustainable societies, contribute to tackle poverty traps and…
- Trial name
- NPECDP-UKA (NCT04210362)
- Testing
- Workshops on responsive caregiving
- Where
- Mexico
- Volunteers
- 764 people, healthy volunteers welcome
- Sponsor
- Amado David Quezada Sánchez
Cerebral Palsy Children, Motor Disabilities
Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy
The goal of this clinical trial is to learn if a therapist training program can help providers in Part C Early Childhood Settings use powered mobility (PM) with young children who have cerebral palsy (Gross Motor Function…
- Conditions
- Cerebral Palsy Children, Motor Disabilities, Developmental Disability, Rehabilitation
- Trial name
- NCT07220590
- Testing
- Therapist Training on Powered Mobility Implementation, Powered Mobility Intervention for Child-Caregiver Dyads
- Where
- 3 sites in United States
- Volunteers
- 70 people
- Sponsor
- Oregon Health and Science University
Posttraumatic Stress Disorder (PTSD)
Imagery Rescripting in the Treatment of Post Traumatic Stress Disorder (PTSD) Following Early Chronic Interpersonal Trauma
Imagery Rescripting (IR)is a promising treatment for PTSD in adult survivors of early, chronic, interpersonal trauma (e.g. Smucker \& Dancu, 1999).
- Trial name
- NCT01464892
- Testing
- Imagery Rescripting and Reprocessing Therapy, STAIR + Imagery Rescripting
- Where
- Netherlands
- Volunteers
- 61 people
- Sponsor
- University of Amsterdam
Parenting
ChiPP2: A Trauma-Informed Program for City School Parents
Purpose of this study is to assess the prevalence of adverse childhood experiences (ACEs) and positive childhood experiences (PCEs) among parents enrolled in the Chicago Parent Program (ChiPP) in their child's school and whether…
- Trial name
- ChiPP2 (NCT04968314)
- Testing
- Chicago Parent Program
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Early Childhood Development
Evaluating Effects of Integrating ECD Activities Into Bangladesh Government's Urban Lactating Mothers Allowance Program for the Poor on Children's Cognition and Behavior in Rangpur City Corporation, Bangladesh
Burden: Provision of health care to urban poor population is a great challenge because of supply and demand barriers in the urban health system, which is considered patchy and fragmented.
- Trial name
- NCT03753646
- Testing
- Lactating allowance and psycho social stimulation
- Where
- Bangladesh
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Early Detection of Cancer
National Breast and Thyroid Screening After a Treatment Received Against a Cancer During Childhood
The DENACAPST programme represents an important initiative to provide near nation-wide roll-out of an important cancer surveillance program for childhood cancer survivors.
- Trial name
- DENACAPST (NCT03183401)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Ankyloglossia
Long-term Follow-up of Infant Frenotomy/Frenectomy Through Early Childhood
Ankyloglossia (tongue tie) is an anatomically shortened lingual frenum that impairs appropriate tongue mobility. Initial clinical diagnosis of tongue tie usually begins during infancy with abnormal breastfeeding though not all…
- Trial name
- NCT07110948
- Testing
- Tongue tie release
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University of Alberta
Early Childhood Caries
Effectiveness of SDF in Arresting Dental Caries in Preschool Children
Background: Tooth decay in children (Early childhood caries, or ECC) is a common childhood disease. Poor dentition significantly affects the nutrition, growth, development and general health of children.
- Trial name
- NCT02385474
- Testing
- 12% SDF, 38% SDF
- Where
- China
- Volunteers
- 888 people
- Sponsor
- The University of Hong Kong
Cardiovascular Disease
Nitric Oxide Bioavailability and Early Life Stress (NO-Stress)
Cardiovascular disease is the leading cause of death in the United States. Other studies have shown that stress, early in life, could be a risk factor for cardiovascular disease, later in life.
- Trial name
- NO-Stress (NCT02115724)
- Testing
- Antioxidant cocktail, Biopsy, NMD; 0.4mg sub-lingual nitroglycerin spray
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Augusta University
Teaching Healthy Cooking Skills to Parents and Their Preschool Children
Cooking HEalthy and Facilitating Early Childhood Development: CHEF-ED Study
This study aims to test a new online program we developed for parents and their preschool children, called CHEF-ED. CHEF-ED focuses on healthy cooking, parental feeding practices, and involving children in home food preparation.
- Trial name
- CHEF-ED (NCT06940817)
- Testing
- CHEF-ED + Food Delivery, Food Delivery Only
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Overweight, Childhood, Obesity Prevention
High Five! - School-based Prevention of Overweight and Obesity Among 6 to 9 Year Olds
The goal of this interventional study is to assess the effectiveness of the school-based "High Five!" program in reducing overweight, obesity and high blood pressure in children aged 7-9 years old.
- Conditions
- Overweight, Childhood, Obesity Prevention, Blood Pressure
- Trial name
- DINO-PL (NCT07357857)
- Testing
- High Five
- Where
- Poland
- Volunteers
- 659 people, healthy volunteers welcome
- Sponsor
- Institute of Mother and Child, Warsaw, Poland
Functional Constipation, Emotional Problems
Early Screening of Emotional, Behavioral and Autism Spectrum Disorders in Children With Functional Constipation.
A significant group of children with functional constipation (FC) continues to have symptoms despite recommended standard therapy. Underlying psychiatric problems could explain therapy resistance.
- Conditions
- Functional Constipation, Emotional Problems, Behavioural Problems, Developmental Disorder
- Trial name
- NCT03614000
- Testing
- Screening Questionnaires
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Pulmonary Dysfunction
Early Pulmonary Dysfunction in Childhood Cancer Patients
This longitudinal, prospective, multicentre study is to monitor lung function prospectively in childhood cancer patients after diagnosis.
- Trial name
- SWISS-Pearl (NCT05427136)
- Testing
- Lung function measurements, Breath Analysis, Magnetic resonance imaging (MRI)
- Where
- 5 sites in Switzerland
- Volunteers
- 140 people
- Sponsor
- University Children's Hospital Basel
Early Childhood Development in HIV-Exposed Children
Evaluation of an Early Childhood Development Intervention for HIV-Exposed Children in Cameroon
There is substantial evidence that early childhood development (ECD) programming can improve child health and development outcomes.
- Trial name
- NCT03195036
- Testing
- Home-based ECD services
- Where
- Cameroon
- Volunteers
- 230 people
- Sponsor
- Duke University
Early Childhood Caries
Clinical Efficiency and Child's Behavior of Hall Versus SDF Techniques in the Management of Carious Primary Molar:
This study will compare two non- invasive treatment options: Hall technique and 38% Silver diamine fluoride. Both are methods used to create a more favorable environment without removal of caries leading to the arrest of the…
- Trial name
- NCT04737057
- Testing
- SDF, Hall technique
- Volunteers
- 72 people
- Sponsor
- Cairo University
Early Childhood Caries, Oral Hygiene
Acceptance and Efficacy of a Digital Application Among Parents to Control Early Childhood Caries
Few educational oral health applications, directed to the preschool children under the age of six years are available world-wide.
- Conditions
- Early Childhood Caries, Oral Hygiene, Oral Health
- Trial name
- FU-APP (NCT05515510)
- Testing
- FU-APP, Oral health recommendations
- Where
- Germany
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Dental Caries in Children, Diet Habit
Maternal Control of the Child's Feeding, Child's Eating Behavior and Early Childhood Caries in Preschoolers
Dental caries in children is considered one of the most prevalent oral diseases of this age group, leading to significant manifestations presenting as pain, interference with feeding, higher risk of developing dental caries in…
- Conditions
- Dental Caries in Children, Diet Habit, Dietary Exposure, Eating Behavior
- Trial name
- NCT06898918
- Where
- Egypt
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Childhood Obesity
Coordination of Care Between Pediatricians and Women Infants & Children Nutritionists
WEE Baby Care is a 6 month intervention that coordinates care across multiple settings- health care clinics and WIC clinics on responsive parenting practices to increase parenting competence thereby preventing infant rapid weight…
- Trial name
- WEE (NCT03482908)
- Testing
- Early healthy lifestyles, Responsive parenting curriculum, Data sharing/coordination
- Where
- United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- Penn State University