Clinical trials: Early Childhood
Early Childhood Caries
Clinical Evaluation of High Viscosity Glass Ionomer Strip Crowns in Primary Maxillary Incisors
The aim of this study was to evaluate the clinical success of modified celluloid strip crown restorations applied using interim therapeutic restoration and high-viscosity glass ionomer cement to the maxillary anterior teeth of…
- Trial name
- NCT05838469
- Testing
- Pediatric Strip Crown and High Viscosity Glass Ionomer Cement
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dietary Habits, Physical Inactivity
HEART at Head Start Pilot (Healthy Eating, Activity, Relaxation Trial)
With funding from the United States Department of Agriculture (USDA), the Tufts University's Friedman School of Nutrition Science and Policy will be implementing a new, health and wellbeing program for Head Start educators at…
- Conditions
- Dietary Habits, Physical Inactivity, Sleep Hygiene
- Trial name
- HEART (NCT06346574)
- Testing
- Experimental
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tufts University
Brain and Central Nervous System Tumors, Kidney Cancer
Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid Tumors
RATIONALE: Tubefeeding may help maintain good nutrition and lessen weight loss in younger patients receiving chemotherapy for cancer.
- Conditions
- Brain and Central Nervous System Tumors, Kidney Cancer, Leukemia, Liver Cancer
- Trial name
- NCT00624962
- Testing
- nutritional intervention, therapeutic nutritional supplementation
- Sponsor
- Vanderbilt University
Prenatal Alcohol Exposure, Fetal Alcohol Spectrum Disorders
Families Moving Forward Bridges: An Early Intervention for Infants and Toddlers With PAE With or At-risk for FASD
This is an unblinded, feasibility study of an adapted positive parenting intervention to be carried out in a small sample (n=12 dyads) of young children with FASD and their primary caregiver in King County, WA.
- Trial name
- NCT06935461
- Testing
- Families Moving Forward Bridges
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Washington
Socioemotional Development
Optimizing a School-Based Therapeutic Play Intervention for Preschool Students
The goal of this clinical trial is to optimize a school-based therapeutic play intervention in preschool students with mild to moderate school adjustment difficulties. The aims are: 1.
- Trial name
- NCT07609342
- Testing
- Individual play sessions, Peer play sessions, Classroom push-in sessions
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- The Children's Institute
Pregnancy Related, Vitamin B 12 Deficiency
Vitamin B12 Supplementation During Pregnancy on Cognitive Development
Scientific basis: Globally, vitamin B12 deficiency is one of the most common micronutrient deficiencies. The only relevant source of vitamin B12 is animal-source foods and poor gut function may decrease absorption.
- Conditions
- Pregnancy Related, Vitamin B 12 Deficiency, Anemia
- Trial name
- VitaPreg (NCT03071666)
- Testing
- cobalamin
- Where
- Nepal
- Volunteers
- 800 people
- Sponsor
- Centre For International Health
Pediatric Obesity, Risk Reduction Behavior
FirstStep2Health Intervention
This project will determine the preliminary efficacy of an innovative intergenerational intervention among Head Start preschoolers, aged 3-5 years, and their caregivers.
- Conditions
- Pediatric Obesity, Risk Reduction Behavior, Early Intervention, Intergenerational Relations
- Trial name
- NCT04164277
- Testing
- Caregiver Component., Caregiver-Preschooler Learning., Center-based Preschooler Component.
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Parenting, Child Development
Room to Grow Evaluation for Children
This research project is a small-scale randomized controlled trial (RCT) of an innovative program based in New York City called Room to Grow (RtG).
- Trial name
- RTG (NCT04226053)
- Testing
- Parenting, Child Development
- Where
- United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Columbia University
Leukemia, Childhood, Solid Tumor, Childhood
Observational MyPal-Child Study on the ePRO-based Early Palliative Care Digital System in Paediatric Oncology Patients
The main aim of the study is the evaluation of the feasibility of comprehensive service which has been developed while considering patient-orientated needs.
- Trial name
- MyPal4Kids (NCT04381221)
- Where
- 3 sites in Czechia, Germany
- Volunteers
- 100 people
- Sponsor
- Centre for Research and Technology Hellas
Obesity, Childhood
Deimplementation of Inappropriate Feeding Practices in Early Care and Education Settings
Arkansas and Louisiana have among the highest rates of adult obesity in the United States at 38.7% and 38.6%, respectively. Prevention and intervention efforts are needed to reduce the number of children who will become obese…
- Trial name
- NCT07107321
- Testing
- WISE Words
- Where
- United States
- Volunteers
- 2,640 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Early Childhood Caries (ECC)
Analysis of Salivary Proteins in Young Children as an Device to Improve Caries Risk Assessment
The goal of this observational study is to learn if the composition of salivary proteins in 3-year-old children, from communities with documented varying caries risks, can be used to identify future diagnostic predictors for…
- Trial name
- DecodECC (NCT06957509)
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Parent-Child Relations, Parenting
CenteringParenting Clinical Intervention on Kindergarten Readiness in Early Childhood
Disparities in health begin in early childhood. Early life experiences influence brain development and have significant implications on future health and developmental outcomes.
- Conditions
- Parent-Child Relations, Parenting, Child Development, Child Behavior
- Trial name
- NCT03641092
- Testing
- CenteringParenting Intervention, Routine Well Child Care
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Maternal Behavior, Body Weight
Maternal and Infant Growth Study
Rapid growth early in infancy is a risk factor for obesity and cardiovascular disease later in the lifespan. Evidence is limited, but both pre- and postnatal factors are associated with early rapid growth, and include high…
- Conditions
- Maternal Behavior, Body Weight, Infant Behavior
- Trial name
- RIF (NCT02893319)
- Testing
- Feeding and growth differences, 5oz vs 8oz bottle
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Leann Birch
Extrahepatic Portal Vein Obstruction (EHPVO)
Radiological Intervention for Childhood Extra-Hepatic Portal Vein Obstruction
This study evaluates the safety and effectiveness of percutaneous portal vein recanalization (PVR) with stent placement, with or without transjugular intrahepatic portosystemic shunt (TIPS), in restoring portal flow and improving…
- Trial name
- NCT07867587
- Testing
- Portal Vein Recanalization and Stenting
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Ain Shams University
Lymphoma
Protein Biomarker Levels in Tissue Samples From Young Patients With Low-risk Hodgkin Lymphoma
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01366157
- Testing
- microarray analysis, protein expression analysis, immunohistochemistry staining method
- Volunteers
- 23 people
- Sponsor
- Children's Oncology Group
Childhood Obesity
Early Adiposity Rebound Amongst 4-y.o. Children and Overweight Risk Amongst 11-y.o Children : Third Phase of a Cohort Study in Franche-Comté
This study aims to assess different methods for early adiposity rebound determination at the age of 4/5 years old according to current medical screening criteria in schools, and to assess their prognostic value for obesity…
- Trial name
- CoOP (NCT03342092)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 868 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Early Childhood Caries
Investigation of Supragingival Plaque Microbiome in Early Childhood Caries
The purpose of this study was to characterize the supragingival plaque microbiome in children with early childhood caries and identify potential microorganisms associated with caries.
- Trial name
- NCT04456335
- Testing
- Collection of supragingival plaque from caries free children
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Trakya University
Motor Activity, Parent-Child Relations
The Expansion of a Parent-focused Physical Literacy Intervention for Early Childhood Called PLAYshop
The PLAYshop program is a novel, brief, theory-based, parent-focused physical literacy intervention, that can help mitigate the impacts of the COVID-19 pandemic on physical activity of children from diverse and vulnerable…
- Conditions
- Motor Activity, Parent-Child Relations, Child Development
- Trial name
- NCT05436197
- Testing
- PLAYshop Program
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Infant Sleep Problem
The Role of Circadian Rhythm in the Effect of Sleep Intervention on Obesity Prevention in Early Childhood
Over the last 40 years, obesity has increased dramatically among all age groups, especially in infants and young children, and became an important global public health challenge, thus early prevention is the highest priority.
- Trial name
- NCT05159141
- Testing
- Behavioral sleep intervention
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Healthy
The Early Childhood Friendship Project - Phase 3
The purpose of this study is to assess the impact of the Early Childhood Friendship Project (ECFP) on changes in aggression/peer victimization subtypes, prosocial behavior, and social and academic competence with a…
- Trial name
- ECFP-3 (NCT05908461)
- Testing
- Early Childhood Friendship Project
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo