Clinical trials: Early Childhood Caries, active
Dental Caries, Dental Caries in Children
Technology-enabled Anticipatory Guidance and Peer Support in Empowering Parents to Prevent Early Childhood Caries
Early Childhood Caries (ECC) is a significant clinical and public health challenge that the world and the Singapore population are facing.
- Conditions
- Dental Caries, Dental Caries in Children, Diet Habit
- Trial name
- NCT06558955
- Testing
- Technology-enabled anticipatory guidance and peer support, Conventional health education
- Where
- Singapore
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Candida Infection, Oral Thrush
Oropharyngeal Candidiasis (OPC) and S-ECC
The overall objective of this study is to investigate the association of early Candida infection (known as oral thrush or oropharyngeal candidiasis, OPC) in children during the first year of life with the onset and severity of…
- Conditions
- Candida Infection, Oral Thrush, Early Childhood Caries
- Trial name
- Oral-Thrush (NCT05761197)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Temple University
Pediatric Dental General Anesthesia, Restoration
Clinical Performance and Failure Rates of Restorations Following Pediatric Dental Rehabilitation Under General Anesthesia
Full-mouth dental rehabilitation under general anesthesia (GA) is frequently required for young children with extensive dental caries, behavioral challenges, or special healthcare needs.
- Conditions
- Pediatric Dental General Anesthesia, Restoration, Clinical Performance, Full Mouth Rehabilitation
- Trial name
- NCT07827833
- Testing
- Routine Restorative Materials and Treatment Methods
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Tanta University
Early Childhood Caries (ECC)
Caries Risk in Children Treated Under General Anesthesia for Early Childhood Caries
This observational, cross-sectional study aims to evaluate the current caries risk profiles of children who underwent dental treatment under general anesthesia (GA) for early childhood caries (ECC) between 2015 and 2020 at Aydın…
- Trial name
- NCT07330570
- Testing
- Caries Risk Assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Dental Caries in Children, Diet Habit
Maternal Control of the Child's Feeding, Child's Eating Behavior and Early Childhood Caries in Preschoolers
Dental caries in children is considered one of the most prevalent oral diseases of this age group, leading to significant manifestations presenting as pain, interference with feeding, higher risk of developing dental caries in…
- Conditions
- Dental Caries in Children, Diet Habit, Dietary Exposure, Eating Behavior
- Trial name
- NCT06898918
- Where
- Egypt
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Oral Health in Pregnancy and Early Childhood, Early Childhood Caries (ECC)
Midwives' Perspectives on Oral Health in Pregnancy and Early Childhood: A Cross-Sectional Online Survey
This study aims to explore how midwives in Germany perceive their professional role in the context of oral health of pregnant women and young children.
- Conditions
- Oral Health in Pregnancy and Early Childhood, Early Childhood Caries (ECC), Health Promotion by Midwives
- Trial name
- NCT07572799
- Volunteers
- 200 people
- Sponsor
- University Medical Center Goettingen
Dental Caries, Obesity Risk
Mothers' Action Project for Child Health
This randomized controlled trial will recruit Bangladeshi mothers and their young children into a 12 month intervention that provides child health and oral health education and seeks to build social networks among mothers.
- Trial name
- MAP-CH (NCT06753669)
- Testing
- health education and social network building, dental referral and educational materials
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Dental Caries
Sequential PVP-I and FV
This prospective cohort study in children will determine if: topical povidone iodine 10% followed by topical fluoride varnish is superior to placebo iodine followed two different varnishes alone to prevent tooth decay (dental…
- Trial name
- NCT07683910
- Testing
- fluoride varnish, 2.5%, topical fluoride, 2.1%, Povidone Iodine Topical
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- Advantage Silver Dental Arrest, LLC
Early Childhood Caries (ECC)
Preventing Early Childhood Caries With a Silver Diamine Fluoride Gel
The objective is to compare the efficacy of SDF gel with that of NaF varnish in preventing carious lesions in preschool children when applied at half-yearly intervals over a 24-month period.
- Trial name
- NCT07455604
- Testing
- Silver diamine fluoride gel, Sodium Fluoride varnish
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Healthy Women, Caries of Infancy
The Effectiveness of Motivational Interviewing in Preventing Early Childhood Caries Among Mothers of Infants in Terengganu.
This study will be conducted in Ministry of Health (MOH) Maternal and Child Health Clinics (MCHCs) and MOH dental clinics in Setiu and Hulu Terengganu, selected for their similar sociodemographic characteristics.
- Trial name
- NCT07538219
- Testing
- Anticipatory Guidance Using Motivational Interviewing, Conventional Ministry of Health Anticipatory Guidance
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Early Childhood Caries
Povidone Iodine Efficacy Study
This is a single center, randomized, double-blind, placebo-controlled Phase II clinical trial (RCT) to evaluate the efficacy of topical 10% Polyvinylpyrrolidone-Iodine (PVPI) to prevent new caries lesions when applied to the…
- Trial name
- PIES (NCT05272254)
- Testing
- 10% povidone iodine + FV
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Early Childhood Caries (ECC)
Analysis of Salivary Proteins in Young Children as an Device to Improve Caries Risk Assessment
The goal of this observational study is to learn if the composition of salivary proteins in 3-year-old children, from communities with documented varying caries risks, can be used to identify future diagnostic predictors for…
- Trial name
- DecodECC (NCT06957509)
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Early Childhood Caries, Health Care Acceptability
Effectiveness and Acceptability of SDF Compared to ART for the Management of Early Childhood Caries
The goal of this clinical trial is to assess the acceptability and clinical effectiveness of Silver Diamine Fluoride (SDF) in comparison with Atraumatic Restorative Treatment (ART) in Early Childhood Caries (ECC) management at…
- Trial name
- SDF and ART (NCT06786975)
- Testing
- Silver Diamine Fluoride, Atraumatic Restorative Treatment
- Where
- Chile
- Volunteers
- 156 people
- Sponsor
- Universidad de La Frontera
Oral Health, Dental Caries
WhatsApp Messages to Improve Mothers' Oral Health Knowledge and Children's Toothbrushing
Tooth decay is one of the most common health problems in young children in Saudi Arabia. Brushing twice a day with fluoride toothpaste is one of the most effective ways to prevent it, but preschool children cannot do this…
- Conditions
- Oral Health, Dental Caries, Health Behavior, Oral Hygiene
- Trial name
- NCT07765654
- Testing
- Standardized Face-to-Face Oral Health Education, WhatsApp-Based Oral Health Messages
- Volunteers
- 106 people
- Sponsor
- King Abdulaziz University
Early Childhood Caries
Study of Obstacles and Barriers to Changing Risky Eating Behaviors in Families of Children With Severe Early Childhood Caries (QUALIKIDS).
Dental caries is the most common chronic disease in children, and its early form-Early Childhood Caries (ECC)-which particularly affects children under the age of six, represents a major public health problem worldwide.
- Trial name
- QUALIKIDS (NCT07377240)
- Testing
- Interview
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Early Childhood Caries
Oral Health Intervention for Caregivers of Children Presenting for Dental Surgery
Too many young children, particularly those living in poverty, present for dental surgery under anesthesia - an expensive, potentially dangerous, short-term fix that often results in recurring oral health disease and subsequent…
- Trial name
- PROTECT (NCT07220850)
- Testing
- Behavioral Treatment
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- University of Illinois Chicago
Early Childhood Caries
Salivary Cystatin S Levels in a Group of Egyptian Children
Aim of the study 1. Measuring the levels of salivary cystatin S protein and salivary buffering capacity to determine their relation to early childhood caries. 2.
- Trial name
- NCT05716867
- Testing
- Measurement of salivary cystatin S protein levels in saliva
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Early Childhood Caries (ECC)
Zirconia Crowns Versus Extraction of Primary Anterior Teeth
Severely mutilated anterior primary teeth in preschool children are frequently managed by extraction. However, premature loss of anterior primary teeth has been associated with adverse functional, developmental and psychosocial…
- Trial name
- NCT07719478
- Testing
- Zirconia Crown, Extraction
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Passant Nagy
Severe Early Childhood Caries, Caries
Construction of a Multidimensional Risk Prediction Model for Severe Early Childhood Caries
This study aims to address the high prevalence and recurrence rate of severe early childhood caries (S-ECC) by breaking away from the traditional single biological factor perspective and introducing the theories of "24-hour…
- Trial name
- NCT07335744
- Testing
- questionnaire survey
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Caries,Dental
Evaluation of Different Cementation Materials Used in Prefabricated Pediatric Zirconia Crowns
Today, with increasing aesthetic demands; the need for materials that are both durable and compatible with the appearance of natural teeth is increasing in paediatric dentistry.
- Trial name
- NCT06690229
- Testing
- glass ionomer cement, self-adhesive resin cement, resin modified glass ionomer cement
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Aydin Adnan Menderes University