Clinical trials: Early Interventions
Melanoma
Feasibility of an Enhanced Symptom Monitoring and Expedited Subspecialty Care Referral Intervention to Improve Side Effect Management for Patients With Melanoma Receiving an Immune Checkpoint Inhibitor
This clinical trial tests the feasibility of patient reported outcomes monitoring with early, rapid immunotherapy toxicity subspecialty care to improve side effect management for patients with melanoma receiving an immune…
- Trial name
- NCT07660666
- Testing
- Electronic Health Record Review, Internet-Based Intervention, Patient Navigation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Cardiovascular Diseases
Early Intervention to Promote Cardiovascular Health of Mothers and Children
The goal of this clinical trial is to examine whether a multi-component intervention delivered during pregnancy and after delivery can improve the cardiovascular health of pregnant individuals enrolled in home visiting programs…
- Trial name
- ENRICH (NCT05856162)
- Testing
- ENRICH pilot intervention (full intervention), ENRICH pilot intervention (partial intervention: only diet and physical activity)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Nutritional Deficiencies, Developmental Delay
Project Grow Smart: Intervention Trial of Multiple Micronutrients and Early Learning Among Infants in India
Project Grow Smart evaluates the impact fortification with multiple micronutrient powders (MNP) vs. placebo (one vitamin) on child development (primary outcome) and on micronutrient status, growth, and morbidity (secondary…
- Trial name
- GrowSmart (NCT01660958)
- Testing
- MNP, Early Learning
- Where
- India
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Maternal Dietary Diversity, Iron-Folic Acid Supplementation
A Feasibility Study of Integrating Maternal Nutrition Interventions Into Antenatal Care Services in Ethiopia
Alive \& Thrive (A\&T) is an initiative that supports the scaling up of nutrition interventions to save lives, prevent illnesses, and contribute to healthy growth and development through improved maternal nutrition, breastfeeding…
- Conditions
- Maternal Dietary Diversity, Iron-Folic Acid Supplementation, Early Initiation of Breastfeeding
- Trial name
- NCT04125368
- Testing
- Health Facility Interventions, Community Interventions, Health System Interventions
- Where
- United States
- Volunteers
- 4,256 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Diabetes Mellitus, Type 1
Early Dietary Intervention and Later Signs of Beta-Cell Autoimmunity
The proposed mechanistic formula feeding study sets out to identify the mechanism(s) by which an extensively hydrolyzed casein formula is able to protect children at risk for type 1 diabetes (T1D) from beta-cell autoimmunity.
- Trial name
- EDIA (NCT01735123)
- Testing
- dietary intervention
- Where
- Finland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Hazardous Drinking, Harmful Drinking
Testing the Efficacy of an Online Alcohol Intervention in a Workplace Setting
The purpose of this study is to test - in a workplace setting - if an online multi-session alcohol intervention improves treatment effect over and above a single session screening with feedback.
- Trial name
- NCT01931618
- Testing
- Online screening and feedback, Online booklet., Online multi session follow-up
- Where
- Norway
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Reading Disability
Executive Function in Early Childhood
Despite the fact that a substantial number of school age children struggle with both reading and math acquisition, the brain mechanisms of the overlapping aspects of reading and math skills, thought in part to be linked via…
- Trial name
- NCT03713125
- Testing
- Reading Tutoring
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Developmental Disability
Benefits of Coding Training on Young Adults With Developmental Disabilities
The purpose of the present study is to develop and evaluate the Technology Early Career Preparation Intervention (TECH-Prep) program with African American high school students with developmental disabilities.
- Trial name
- NCT05132491
- Testing
- TECH-Prep Intervention
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Pregnancy
Effectiveness of Online-Based "Pregnant Women Care Cadres" Intervention on Husband Support in Early Detection of High Risk in Medan Maimun Area
The goal of this quasi-experimental study is to evaluate whether an online-based "Caring for Pregnant Women" intervention delivered through community health cadres can improve husband support in the early detection of high-risk…
- Trial name
- NCT07430033
- Testing
- Online-Based "Caring for Pregnant Women" Intervention Through Community Health Cadres to Enhance Husband Support in Early Detection of High-Risk Pregnancy
- Where
- Indonesia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Siti Saidah Nasution
Behavioral Inhibition, Anxiety
A Multi-Method Early Intervention Program for Inhibited and Anxious Preschoolers
This project aims to develop and evaluate a novel early intervention program that targets the specific risk factors implicated in the development and persistence of shyness, social reticence, and withdrawal in children.
- Trial name
- NCT03486860
- Testing
- Parent Psychoeducation, Turtle Program
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Anxiety Symptoms, Depressive Symptoms
Effects of a Single-session Implicit Theories of Personality Intervention on Early Adolescent Psychopathology
The goal of the project is to test whether a single-session intervention teaching incremental theories of personality, or the belief that one's personality is malleable, can strengthen recovery from social stress and reduce the…
- Trial name
- NCT03132298
- Testing
- Implicit Theories of Personality Program, Control Program
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Harvard University
Child Behavior Disorders, Parenting
RCT of Brief Universal Parenting Program to Prevent Child Behavioural and Emotional Difficulties in Greece
This study investigates the impact of a Triple P Seminar Series on positive parenting for universal prevention of behavioural and emotional difficulties in a general Greek sample of parents with children aged 2 to 12.
- Trial name
- NCT02030730
- Testing
- Triple P Seminar Series
- Where
- United Kingdom
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Chronic Illness, Heart Failure - NYHA II - IV
An Optimization Pilot to Optimize An Early Palliative Care Intervention for Advanced Heart Failure
Using a highly innovative methodology, the Multiphase Optimization Strategy (MOST), the purpose of this randomized factorial pilot trial is to identify feasibility, acceptability, and preliminary efficacy of components of an…
- Trial name
- UPHOLDS (NCT05879887)
- Testing
- UPHOLDS (Utilizing Palliative Care for Heart Failure Optimized using Lay Navigators to Decrease Suffering)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Neurodevelopmental Disorders, Autism Spectrum Disorder
Early Recognition and Intervention in Siblings at High-risk for Neurodevelopmental Disorder
H1The primary goal of this intervention study is to learn if very early parent-mediated intervention in children at risk for neurodevelopmental disorders in the first year of life can be implemented in routine care, positively…
- Trial name
- ERI-SIBS (NCT06512649)
- Testing
- Early intervention, Active monitoring
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Math Learning Disability, Learning Disabilities
Intervention on Mathematical Problem-Solving Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing and remediating weaknesses in arithmetic skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Learning Disabilities, Learning Disabilities, Child, Dyscalculia
- Trial name
- NCT07778706
- Testing
- Speeded practice training, Arithmetic strategy training
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Stanford University
Stomach Cancer
Development of Free DNA Multi-target Methylated PCR for Auxiliary Diagnosis of Gastric Cancer
This was a case control, non-intervention study jointly developed by Fudan University Cancer Hospital and Shanghai Singlera Genomics Company.
- Trial name
- NCT05336058
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,140 people, healthy volunteers welcome
- Sponsor
- Singlera Genomics Inc.
Resilience
Comparing a Workplace Resilience and a Physical Activity Intervention on Early Childhood Educators Well-being
The goal of this 15-month cluster clinical trial is to compare a resilience and stress management program to a physical activity program for early childhood education (ECE) staff on change in well-being.
- Trial name
- OnWARD (NCT06919952)
- Testing
- Resilience, Physical Activity
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Malnutrition, Dietary Modification
Basic Care Revisited: Early Nutrition Intervention for Outpatients
Early nursing nutrition intervention for outpatients in need of surgery Objective - To investigate the feasibility and effectiveness of screening and an early nursing intervention on malnutrition in outpatients in need for…
- Trial name
- BCR_N (NCT02440165)
- Testing
- Nursing nutrition intervention
- Where
- 2 sites in Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Vitamin D Deficiency
Nutritional Requirements for Vitamin D in Pregnant Women
Randomised, placebo-controlled dose-response intervention study with vitamin D3 in pregnant women.
- Trial name
- DMAT (NCT02506439)
- Testing
- 10 mcg Vitamin D3, 20 mcg Vitamin D3
- Where
- 2 sites in Ireland
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University College Cork
Premature Birth
Early Behavioral Intervention for Preterm Infants
The purpose of this study is to determine the effects of Family Nurture Intervention in preschool aged children between 2.5 and 4.5 years of age who were born prematurely and exhibit developmental deficits.
- Trial name
- EBI (NCT02379130)
- Testing
- Family Nurture Intervention, Play and Nutrition Intervention
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Columbia University