Clinical trials: Early Interventions
Hearing Impairment
Improving Early Intervention in Hearing Impaired Children Using Functional Near-Infrared Spectroscopy (fNIRS)
The goal of this clinical trial is to find out whether hearing test results using functional near-infrared spectroscopy (fNIRS) will help to fast-track early intervention for infants born with a hearing loss.
- Trial name
- NCT05847426
- Testing
- Provision of standard audiological + fNIRS test results, Provision of standard audiological test results only
- Where
- 5 sites in Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Bionics Institute of Australia
Autism Spectrum Disorders
Improving Services and Outcomes for Children With Autism Spectrum Disorder (ASD)
Based on the need to characterize and improve early intervention services for minority and under-resourced children with ASD, this study translates a manualized and proven training model to examine its impact on the use of…
- Trial name
- NCT01800539
- Testing
- Provider Education Model (PEM)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Social Anxiety Disorder of Childhood
Caregiver Mind-Mindedness Training to Alleviate Social Anxiety in Children
This randomized controlled trial (RCT) aims to investigate the efficacy of Mind-Mindedness (MM) training for caregivers as an early intervention for preschool-aged children (4 to 7 years) exhibiting signs of social anxiety.
- Trial name
- CAMPS (NCT06657014)
- Testing
- mind-mindedness
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Heriot-Watt University
Stress, Psychological, Child Behavior
Tele-Wellness Supported App for Family Child Care Home Providers and Families to Promote Health, Family Engagement, and School Readiness Amid COVID-19
The investigators aim to deliver a tele-wellness supported app to Baltimore City's Family Child Care Home (FCCH) providers who are caring for children of Essential Personnel.
- Conditions
- Stress, Psychological, Child Behavior, Social Competence
- Trial name
- NCT04453657
- Testing
- FamilyChildCare (provisional name of app)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Developmental Disability, Development Delay
Early Detection of Children With Developmental Disabilities in Assiut Governorate
The study aimed to determine the effectiveness of a designed training program for nurses toward early detection of developmental disabilities among children (0-3 years).
- Conditions
- Developmental Disability, Development Delay, Motor Delay, Down Syndrome
- Trial name
- NCT06263777
- Testing
- Nurses training program on early detection of disability
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
ADHD
Identification of Early Biomarkers of Pre-school ADHD
ADHD affects around 5% of children and manifests itself as hyperactivity, attention difficulties and motor control and balance problems.
- Trial name
- Bio-PreTDAH (NCT07440992)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dementia, Mild, Mild Cognitive Impairment
CAPABLE Family Pilot - Adapting CAPABLE for Older Adults With Mild Cognitive Impairment (MCI)/Early Stage Dementia and Their Care Partners
The purpose of this study is to test the adapted protocol, CAPABLE Family which builds upon the evidenced based CAPABLE program to address older adults with co-occurring physical disability and mild cognitive impairment or early…
- Conditions
- Dementia, Mild, Mild Cognitive Impairment, Disability Physical, Impairment, Cognitive
- Trial name
- NCT05187117
- Testing
- CAPABLE Family - Open Label Pilot, CAPABLE Family - Randomized Control Trial
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Nutritional Deficiencies, Developmental Delay
Project Grow Smart: Intervention Trial of Multiple Micronutrients and Early Learning Among Infants in India
Project Grow Smart evaluates the impact fortification with multiple micronutrient powders (MNP) vs. placebo (one vitamin) on child development (primary outcome) and on micronutrient status, growth, and morbidity (secondary…
- Trial name
- GrowSmart (NCT01660958)
- Testing
- MNP, Early Learning
- Where
- India
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Motor Activity, Parent-Child Relations
PLAYshop: A Parent-focused Physical Literacy Intervention for Early Childhood
The PLAYshop program is a novel, brief, theory-based, parent-focused physical literacy intervention designed to address this major public health issue of childhood physical inactivity and to support families.
- Conditions
- Motor Activity, Parent-Child Relations, Child Development
- Trial name
- NCT05255250
- Testing
- PLAYshop
- Where
- Canada
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Child Development, Adaptive Behavior
Effects of Music and Storytelling on Linguistic, Socioemotional, and Adaptive Development in Children Aged 12-36 Months: an Intervention Protocol in Municipal Early Childhood Centers
This randomized clinical trial aims to evaluate the impact of a structured enriched environment on the linguistic, adaptive behavior, and socioemotional development of children aged 12 to 36 months.
- Conditions
- Child Development, Adaptive Behavior, Early Child Development, Music Education
- Trial name
- MUS-STORY (NCT06831851)
- Testing
- Storytelling Sessions, Music Education Sessions, Parental Guidance Sessions
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Child Development, Father-Child Relations
A Quasi-experimental Evaluation of the Malezi Program in Tanzania
The quality of caregiving and the parent-child relationship is critical for early child development (ECD) and has been shown to be modifiable.
- Conditions
- Child Development, Father-Child Relations, Knowledge, Attitudes, Practice, Safety Issues
- Trial name
- Malezi II (NCT05244161)
- Testing
- RMV-ECD
- Where
- Tanzania
- Volunteers
- 1,248 people, healthy volunteers welcome
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
Mental Disorder
VIA Family 4 Year Follow-up of a Family-based Preventive Intervention
This study aims to investigate the long-term effects (2.5 years after post-intervention) of a preventive family-based intervention (VIA Family) compared with treatment as usual (TAU) for children of parents with a severe mental…
- Trial name
- NCT06218693
- Testing
- VIA Family, Treatment As Usual (TAU)
- Where
- Denmark
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Early Intervention, Educational, Health Promotion
Educational Nutritional Intervention for Adolescents
Randomized controlled trial by conglomerates whose objective is to evaluate the effectiveness of an educational nutritional intervention, based on the Social Cognitive Theory, for the increase in the consumption of vegetables and…
- Conditions
- Early Intervention, Educational, Health Promotion, Feeding Behavior, Adolescent Health
- Trial name
- NCT05403060
- Testing
- ALIADA: Alimentación, Adolescencia y Ambiente
- Where
- Mexico
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Centro Universitario de Ciencias de la Salud, Mexico
Infant Growth
Introduction of Fish Early in the Complementary Feeding Period to Improve Infant Growth
The aim of the study is to provide proof that giving fish during early complementary feeding improves infant linear growth outcomes.
- Trial name
- NCT03993860
- Testing
- Fish Powder, Sorghum powder
- Where
- Zambia
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Mukuba University
Parental Language Behaviors
Project ASPIRE Efficacy Pilot: Achieving Superior Parental Involvement for Rehabilitative Excellence
The purpose of the proposed exploratory research protocol is to investigate the feasibility and efficacy of Project ASPIRE, a parent-directed intervention aiming to increase parental skills and enrich children's early language…
- Trial name
- ASPIRE (NCT01753661)
- Testing
- Linguistic Feedback Report, Multimedia Education Sessions, EI-As-Usual
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Preeclampsia (PE) Risk
An Interventional Pilot Study on the Effect of Extra Virgin Olive Oil on Women with Preeclampsia Risk
This study explores the potential benefits of Extra Virgin Olive Oil from early harvested olives (EVOOEH) in reducing the risk of preeclampsia (PE) in high-risk pregnant women.
- Trial name
- NCT06759545
- Testing
- Dietary MOH recommendations and daily addition of 42 ml (three tablespoon) at each morning of EVOOEH, Dietary MOH recommendations
- Where
- Israel
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Yaniv Ovadia
Premature - Weight 1000g-2499g or Gestation of 28-37weeks, Premature Baby 26 to 32 Weeks
Comparison of Two Early Treatments for Premature Babies and Their Effects Over Time
According to the latest World Health Organization report, prematurity is a major health issue, recognized as a significant vulnerability factor contributing to the emergence of neurodevelopmental disorders.
- Conditions
- Premature - Weight 1000g-2499g or Gestation of 28-37weeks, Premature Baby 26 to 32 Weeks, Premature Baby 33 to 36 Weeks, Premature Between 32 and 36 Weeks of Amenorrhoea
- Trial name
- PREMOTSENS (NCT07261046)
- Testing
- ATVV (Auditory, Tactile, Visual and Vestibular stimulation), Singing
- Where
- 2 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Elsan
Effect of Health Education Regarding Screening Tools of Breast Cancer
Effect of Health Education on Female Teachers' Knowledge and Practices Regarding Early Breast Cancer Detection and Screening in the Jazan Area: A Quasi-Experimental Study
The purpose of this study is to assess the effectiveness of health education in improving the knowledge and practices of female teachers regarding screening tools and the early detection of breast cancer.
- Trial name
- NCT03398057
- Testing
- Health education, Control group
- Where
- Saudi Arabia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Anwar Ali Ahmad Alameer
Premature Birth
Effects of Early Intervention for Preterm Children at School Age
Despite the remarkable achievements in neonatal survival of preterm infants with very low birth weight (VLBW, birth weight < 1,500 g) over the past three decades, improvements have produced little change in their prevalence of…
- Trial name
- NCT01952093
- Testing
- Home-based intervention program, Clinic-based intervention program
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Delirium
Haloperidol Prophylaxis in Older Emergency Department Patients
The investigators propose a multicenter, randomized, double-blinded, placebo-controlled trial to study the effect of additive low-dose haloperidol prophylaxis on top of exciting care in a general population of older patients (age…
- Trial name
- HARPOON (NCT01530308)
- Testing
- Haloperidol
- Where
- 6 sites in Netherlands
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc