Clinical trials: Early Osteoarthritis
Treatment Complication
Autologous Bone Marrow Aspirate Concentrate Injection for the Treatment of Early Osteoarthritis:Baghdad 2022
We present a randomized controlled trial (RCT) to assess the efficacy of autologous bone marrow aspirate concentrate BMAC of 1.8x 10 9 median cellular content in the treatment of early symptomatic knee OA.
- Trial name
- NCT05193877
- Testing
- autologous bone marrow aspirate concentrate by centrifugation
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Global Stem Cell Center, Baghdad
Osteoarthritis
A Randomized Control Trial to Assess Early Clinical and Functional Outcome of the ROCC and LCS Total Knee Implant Designs
This is a prospective Randomised Control Trial to compare the Early Clinical and Functional Outcome of the ROCC and LCS total knee arthroplasty implant designs.
- Trial name
- NCT00755144
- Testing
- LCS Knee, ROCC Knee
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Rheumatoid Arthritis
Tritanium® Study in Japan
The purpose of this study is to evaluate early fixation and stability of the Tritanium cup. It is expected that the Tritanium® cup will be equal to or better than conventional cementless cups in early fixation/stability and meet…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Avascular Necrosis of the Femoral Head
- Trial name
- NCT02552069
- Testing
- Tritanium® cup
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Stryker Japan K.K.
Degenerative Osteoarthritis
A Study to Determine the Safety and Efficacy of TG-C in Subjects With Symptomatic Early Hip Osteoarthritis
A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Determine the Efficacy, Safety, and Dosing of TG-C in Adult Subjects with Symptomatic Early Hip Osteoarthritis.
- Trial name
- NCT05276011
- Testing
- TG-C
- Volunteers
- 255 people
- Sponsor
- Kolon TissueGene, Inc.
Avascular Necrosis, Revision Surgery
Anatomical Shoulder Domelock System Study
The objectives of this study are to confirm safety and performance of the Anatomical Shoulder Domelock System when used in hemi or total shoulder arthroplasty by analysis of standard scoring systems, radiographs and adverse event…
- Conditions
- Avascular Necrosis, Revision Surgery, Conditions Consequent to Earlier Operations, Arthritis, Rheumatoid
- Trial name
- NCT03312465
- Testing
- AS Domelock System
- Where
- 6 sites in Belgium, Germany and 2 more
- Volunteers
- 73 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Hip
H-29 DELTA Multihole TT Study.
This study is aimed to provide a clinical and radiographic evaluation of 50 suitable subjects who underwent a complex primary or a revision Total Hip Arthroplasties with DELTA Multihole TT acetabular cup in 2019 onwards.
- Trial name
- NCT05007067
- Testing
- DELTA Multihole TT
- Where
- Poland
- Volunteers
- 7 people
- Sponsor
- Limacorporate S.p.a
Knee Osteoarthritis
Oxford UKA and HTO Post-market Clinical Study
The purpose of this study is to compare the performance and safety of medial UKA and HTO in the treatment of AMOA in term of functional outcome, radiographic assessment, range of motion, postoperative complications, revision rate…
- Trial name
- NCT04518111
- Where
- China
- Volunteers
- 370 people
- Sponsor
- Zimmer Biomet
Osteoarthritis of Knee, Edema
Microcurrent Stimulation Reduces Post-Operative Swelling and Healing Time Following Knee Replacement Surgery
The purpose of this study is to determine if patients undergoing a total knee arthroplasty (TKA) experience a clinically significant reduction in healing time when treated post operatively with a specific form of micro and…
- Conditions
- Osteoarthritis of Knee, Edema, Wounds and Injuries
- Trial name
- NCT02623660
- Testing
- ODIN1, Standard Care, Diagnostic Device Testing
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bioelectric Research Corporation
Osteochondral Lesions of the Knee Joint, Osteochondritis Dissecans (OCD)
MaioRegen Prime Study for the Treatment of Deep Osteochondral Lesion of the Knee
The present study aims to compare the efficacy and the safety of MaioRegen Prime to Debridement (SSOC) in patients with deep osteochondral lesions of the knee joint.
- Conditions
- Osteochondral Lesions of the Knee Joint, Osteochondritis Dissecans (OCD), Early Osteoarthritis
- Trial name
- OSTEOCONFIRM (NCT07332182)
- Testing
- osteochondral scaffold implant, SSOC
- Where
- 10 sites in United States, Italy
- Volunteers
- 400 people
- Sponsor
- Fin-Ceramica Faenza Spa
Osteoarthritis, Knee
Early Effect of Cingal® Compared to Monovisc® in Patients With Osteoarthritis of the Knee
It is a post-license, multicenter, randomized, single blind, controlled study comparing a single injection of Cingal® (study arm) with a single injection of Monovisc® (control arm).
- Trial name
- EEFFEK (NCT03062787)
- Testing
- Cingal® (Hyaluronic Acid plus Triamcinolone Hexacetonide), Monovisc® (Sodium hyaluronate)
- Where
- 5 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Pharmascience Inc.
Early Stage Osteoarthritis of the CMC-1 Joint
Clinical Evaluation of the Articulinx InterCarpoMetacarpal Cushion (ICMC)for Osteoarthritis of the First CarpoMetacarpal Joint
This study is to evaluate the performance of the Articulinx ICMC (InterCarpoMetacarpalCushion)in the carpometacarpal joint (CMC joint) and to describe the clinical results in patients who have been treated with this device.
- Trial name
- NCT01961570
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Articulinx
Osteoarthritis
Hydroxyapatite (HA) Coating Versus Plasma Porous Spray (PPS) in Press-fit Acetabular Components Early Outcomes With DEXA
The study design comprises a randomized trial of patients undergoing primary total hip arthroplasty using the G7 acetabular system and Taperloc Complete stem comparing regular plasma porous spray with HA coating using Bonemaster…
- Trial name
- NCT02447653
- Testing
- G7 HA Acetabular Component, G7 PPS Acetabular Component
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Hip
H-28 DELTA ST-C and Minima Retrospective Study.
The study aims to assess the clinical and radiographic outcomes of DELTA ST-C in combination with MINIMA stem at 3 years after primary THA surgery, and to evaluate the overall survivorship of the implant.
- Trial name
- NCT05014113
- Testing
- DELTA-ST cup in combination with MINIMA stem
- Where
- Greece
- Volunteers
- 95 people
- Sponsor
- Limacorporate S.p.a