Clinical trials: Early Pregnancy Bleeding
Early Pregnancy Bleeding, Recurrent Pregnancy Loss
Maternal and Newborn Safety Profile of Progestogens in EARLY Pregnancy
This multinational, prospective, active surveillance, registry study following two cohorts will include study participants who are pregnant and seeking any type of medical treatment, including dydrogesterone and other…
- Trial name
- PEARLY (NCT05186779)
- Testing
- Progestagen
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Endometrial Cancer
Detection of Endometrial Cancer Through Risk Modelling
The study goal is to investigate a non-invasive approach to predict endometrial cancer (EC) risk, better understand disease progression and identify opportunities for intervention.
- Trial name
- DETECTR (NCT06268626)
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Acute Kidney Injury
Comparison of Early Proton Pump Inhibitor Initiation Versus Usual Care on Acute Kidney Injury in Hemorrhagic Shock Patients
The investigators propose a single-center, randomized, controlled trial to determine whether early initiation of proton pump inhibitor (PPI), pantoprazole, will decrease acute kidney injury (AKI) for trauma patients presenting…
- Trial name
- Trauma AKI PPI (NCT06531642)
- Testing
- Protonix (Pantoprazole) 40 mg q 12 hrs for 2 days, Protonix (pantoprazole) 40 mg q 24 hrs for 2 days
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Post-Partum Haemorrhage
A Clinical Trial to Study the Effectiveness of a Care Bundle to Prevent Bleeding After a Woman Has Given Birth
Every six minutes a mother dies from postpartum haemorrhage (PPH) in low-resource countries, in the prime of her life and often leaving behind a young family.
- Trial name
- E-MOTIVE (NCT04341662)
- Testing
- E-MOTIVE intervention, Usual care
- Where
- 6 sites in Kenya, Nigeria and 3 more
- Volunteers
- 99,659 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Episiotomy Wound, Anemia
Use of Tranexamic Acid After Vaginal Delivery with Episiotomy a RCT Placebo Control Trail
The objective of this study is to assess the effect of TA treatment on decline in Hb levels following vaginal delivery with an episiotomy, compared to a control group not receiving TA.
- Conditions
- Episiotomy Wound, Anemia, Early Postpartum Hemorrhage, Hemoglobin
- Trial name
- NCT05448456
- Testing
- Tranexamic acid
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Delivery Delayed, Mode of Delivery
Early Versus Delayed Oxytocin Infusion Following Amniotomy in Nulliparous Women
In UKM Medical Centre (UKMMC), delayed oxytocin augmentation at two hours following amniotomy is the routine obstetric practice in spontaneous or induced labour with intact membranes.
- Conditions
- Delivery Delayed, Mode of Delivery, Post Partum Hemorrhage, Uterine Hyperstimulation
- Trial name
- NCT04200599
- Testing
- duration of initiation of oxytocin
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Intact Cord Placental Delivery, Delayed Cord Clamping
Intact Cord Placental Delivery vs Delayed Cord Clamping
The management of the third stage of labour plays a critical role in neonatal transition. Uninterrupted Intact Cord Clamping (UICC), is a clinical approach where the umbilical cord remains unclamped until the placenta is…
- Conditions
- Intact Cord Placental Delivery, Delayed Cord Clamping, Standard Delayed Cord Clamping, Timing of Cord Clamping
- Trial name
- TTC (NCT07713277)
- Where
- Italy
- Volunteers
- 1,979 people, healthy volunteers welcome
- Sponsor
- Azienda ULSS 8 Berica
Postpartum Hemorrhage
Double Simultaneous Uterotonic Agents Versus Single Agent Regimen to Prevent Early Postpartum Hemorrhage
To determine the effectiveness of using two medications simultaneously versus one medication, as is standard of care, in preventing early postpartum hemorrhage.
- Trial name
- NCT05245227
- Testing
- Sublingual Misoprostol, IV Oxytocin
- Where
- United States
- Volunteers
- 1,358 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Uterus Involution, Early Postpartum Hemorrhage
Date Consumption and Uterine Involution
There are many studies in the literature examining the effects of dates on pregnancy, birth and postpartum processes. However, no study has been found that examines the effect of women on the involution process in the early…
- Trial name
- NCT05072769
- Testing
- Date Fruit
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Delayed Umbilical Cord Clamping Benefits, Postpartum Haemorrhage
Timing of Umbilical Cord Occlusion in Premature Babies( <33 w). Delayed vs Early.
Early cord clamping after delivery has been common practice for many decades as part of the active management of the third stage of labour.
- Conditions
- Delayed Umbilical Cord Clamping Benefits, Postpartum Haemorrhage, Intraventricular Haemorrhage
- Trial name
- CODE-P (NCT02187874)
- Testing
- delayed umbilical cord occlusion, early umbilical cord occlusion, Oxytocin
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
First Trimester Bleeding, Pregnancy
Early Pregnancy Evaluation by Three-Dimensional Ultrasound
Early pregnancy is associated with numerous physiologic alterations - many of which are required to establish normal pregnancy outcome.
- Trial name
- NCT00342290
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)