Clinical trials: Early Waking
Stroke, Sleep Apnea
Impact of Early Ventilation in Stroke Outcomes in Patients With Sleep Apnea After First Ever Stroke
To evaluate the impact of early ventilation in stroke outcomes in patients with sleep apnea and first ever stroke, 1 month after stroke.
- Trial name
- NCT04903951
- Testing
- Adaptive Servoventilation (ASV) therapy, Best medical treatment
- Where
- Portugal
- Volunteers
- 90 people
- Sponsor
- Philips Portuguesa S.A.
Lung Cancer, Sleep Disturbance
The Associations of Sleep Disturbance With Therapy Efficacy and Prognosis of Lung Cancer
This is the prospective, observational cohort study (Nezha) to explore the associations of sleep disturbance with progression, efficacy of immune checkpoint inhibitors (ICIs) and prognosis of Lung Cancer.
- Conditions
- Lung Cancer, Sleep Disturbance, Immune Checkpoint Inhibitors, Cancer, Treatment-Related
- Trial name
- Nezha (NCT06975384)
- Testing
- Exposure: sleep disturbance status
- Where
- China
- Volunteers
- 1,270 people
- Sponsor
- Second Xiangya Hospital of Central South University
Osteopathy, PreTerm Neonate
The Effect of Cranial Osteopathy Intervention in Preterm Babies
There are planing to have 2 groups of premature born cases. Each group will include 15 cases. Participants are need to be 28-37 weeks born and no older than post term 6 weeks. All cases are going to be evaluated.
- Conditions
- Osteopathy, PreTerm Neonate, Sensory Profiles, Colic
- Trial name
- NCT06967870
- Testing
- Osteopathic intervention, Home based exercise education
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Fatigue, Depression
Adaptive Symptom Care Using Fish-Based Nutritional Directives Post Breast Cancer
Inflammation has been consistently associated with psychoneurological symptoms (PNS) among breast cancer survivors (BCS). Evidence supporting interventional strategies promoting symptom-self management in reducing…
- Conditions
- Fatigue, Depression, Pain, Sleep Disturbance
- Trial name
- NCT04293874
- Testing
- Personalized Meal Plan, Dietary Omega-3LC intervention
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Connecticut
OSA - Obstructive Sleep Apnea
Multidisciplinary Network OSA Code (Obstructive Apnea Syndrome): Digital Operative Model in Public Health for an Early Diagnosis and Therapy Monitoring
Obstructive Sleep Apnea Syndrome (OSAS) is a sleep related breathing disorder with high epidemiological impact (9-38% of general population), more frequently reported in male gender and increasing with the age.
- Trial name
- DOMOSA (NCT06677580)
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- IRCCS San Raffaele
Alpha-Thalassemia, Beta-Thalassemia
FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases
FLOWER is a completely virtual, nationwide, real-world observational study to collect, annotate, standardize, and report clinical data for rare diseases.
- Conditions
- Alpha-Thalassemia, Beta-Thalassemia, Amyloidosis, Amyotrophic Lateral Sclerosis
- Trial name
- NCT06539169
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- xCures
Mothers, Postpartum Depression
Early Half Swaddling and Kangaroo Care Practices on Maternal Sleep Quality and Postpartum Depression in Term Babies
Aim: In this prospective, randomized controlled study, it was aimed to examine the effects of early half-swaddle and kangaroo care practices in term babies on maternal sleep quality and postpartum depression.
- Trial name
- NCT06348316
- Testing
- Half swaddle, Kangaroo care
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Trakya University
Insomnia Due to Mental Disorder
CBT-I as Early Intervention of Mood Disorders
This study aims to investigate the effectiveness of transdiagnostic nurse-administered 4-session group cognitive behavioral therapy for insomnia (CBT-I) plus standard care, compared to standard care alone, for improving sleep and…
- Trial name
- NCT03000894
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I)
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Shift Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder
Recovery and Early Sleep Tracking Using the SuperPatch REM Patch
A Phase 1 Feasibility Study of the SuperPatch REM Patch for Post-Night-Shift Sleep Recovery in NHS Doctors
- Conditions
- Shift Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder, Shift Work Sleep Disorders
- Trial name
- REST (NCT07785960)
- Testing
- SuperPatch REM Patch
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SuperPatch Limited LLC
Respiratory Failure, Neuromuscular Disease
Ventilator Monitoring in Early Exacerbation Detection
The aim of this study is to determine whether respiratory disease exacerbations (a sudden worsening of symptoms) can be predicted by variables that are monitored by non-invasive ventilators (small machines that assist breathing)…
- Conditions
- Respiratory Failure, Neuromuscular Disease, Chest Wall Disorder, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01644162
- Testing
- iVAPS ventilation
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- ResMed
Insomnia
Testing Utility of Commercially Available Sleep Trackers for Physician-Patient Communication
Sleep related disorders are common in primary care practice. Sleep wear related data has not been utilized to improve sleep related communication between patients and providers.
- Trial name
- NCT03795129
- Testing
- SleepLife Application w/FitBit, FitBit w/Minimal to No SleepLife App.
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Regenstrief Institute, Inc.
Endocrine Responsive Early Breast Cancer
Impact of Adjuvant Treatment With Aromatase Inhibitor on Sleep Disturbances in Postmenopausal Women With Endocrine Responsive Early Breast Cancer
Insomnia is common in Breast cancer patients during adjuvant therapy with aromatase inhibitor. However it is difficult to establish whether it is due to the knowledge of the disease or the treatment administred.
- Trial name
- NCT02166281
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Stroke, Ischemic Attack, Transient
Sleep Disorders Managed and Assessed Rapidly in Transient Ischemic Attack (TIA) and In Early Stroke
The aim of the investigators was to determine whether the immediate management of any detected sleep disorders can improve outcomes in patients who have had a transient ischemic attack (TIA) or minor stroke.
- Conditions
- Stroke, Ischemic Attack, Transient, Sleep Disorders, Sleep Apnea Syndromes
- Trial name
- SMARTIES (NCT01528462)
- Testing
- Expedited Treatment of Sleep Disorders
- Where
- Canada
- Volunteers
- 97 people
- Sponsor
- Sunnybrook Health Sciences Centre
Early Waking, Trauma
Effect of Progressive Early Mobilization in Patients With TBI
traumatic brain injury (TBI) is a major public health concern worldwide. Patients with moderate-severe TBI have high rates of disability at the acute phase and frequently require protracted rehabilitation with prolonged periods…
- Conditions
- Early Waking, Trauma, ICU Acquired Weakness
- Trial name
- NCT04810273
- Testing
- Early progressive mobilization
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- National Taiwan University Hospital
Sleep Problem, Neurobehavioral Manifestations
NapBiome: Targeting Gut Microbiota and Sleep Rhythm to Improve Developmental and Behavioral Outcomes in Early Childhood
The gut-brain axis plays a crucial role in the regulation and development of psychological and physical processes. The first year of life is a critical period for the development of the gut microbiome, which parallels important…
- Trial name
- NapBiome (NCT06396689)
- Testing
- Synbiotic
- Where
- 2 sites in Switzerland
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Petra Zimmermann
Attention Deficit Hyperactivity Disorder
A Pivotal Efficacy Trial to Evaluate HLD200 in Children With ADHD in a Naturalistic Setting
This Phase 3 pivotal efficacy trial will examine the effects of HLD200 (methylphenidate) in patients aged 6-12 years with ADHD in a naturalistic setting.
- Trial name
- NCT02520388
- Testing
- HLD200 methylphenidate hydrochloride (MPH) Capsules
- Where
- 21 sites in United States
- Volunteers
- 163 people
- Sponsor
- Ironshore Pharmaceuticals and Development, Inc
Sepsis, Prognosis
Study on the Establishment of a System for Early Warning and Prognostic Evaluation of Patients With Sepsis
Sepsis is a clinical syndrome with high morbidity and high fatality rate in emergency department. Patients with acute liver or kidney injury are more likely to develop Multiple Organ Dysfunction Syndrome(MODS) secondary to the…
- Conditions
- Sepsis, Prognosis, Liver Injury, Kidney Injury
- Trial name
- NCT05229328
- Testing
- Peripheral blood test
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Sleep Initiation and Maintenance Disorders
Mind-Body Interventions to Mitigate Effects of Media Use on Sleep in Early Adolescents
Eliminating media use is neither feasible at a public health level nor perhaps even desirable given the role it plays in the lives of youth and adults, but mind-body interventions have the potential to mitigate state arousal…
- Trial name
- Sleepazoid (NCT04550507)
- Testing
- Mindful sensory awareness intervention, Mindful sensory awareness + mindful body awareness check-ins intervention
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Depression Anxiety Disorder, Demography, Family
The Effect of Mindfulness-based Stress Reduction Programme Given to Infertile Women
Purpose of the Study This study aims to determine the effect of mindfulness-based stress reduction program given to infertile women on perceived stress, anxiety, depression and salivary cortisol.
- Conditions
- Depression Anxiety Disorder, Demography, Family, Awakening Early
- Trial name
- NCT06283693
- Testing
- mindfulness-based stress reduction
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Sleep Apnea, Stroke
Effect Of Early C-PAP Treatment For Sleep Apnea On Rehabilitation Of Stroke Patients
This is a prospective randomized open label trial with control-to-treatment cross-over. The investigators wish to assess the effectiveness and safety of immediate detection and treatment for Sleep Apnea in Stroke patients.
- Trial name
- NCT02426424
- Testing
- Watchpat, CPAP
- Sponsor
- Soroka University Medical Center