Clinical trials: Early-Onset Scoliosis Deformity of Spine
Early Onset Scoliosis, Congenital Spinal Deformities
The Treatment of Progressive Early Onset Spinal Deformities: A Multi-Center Outcome Study
The purpose of this study is to examine the treatment, both surgical and non-surgical, of patients with any form of early onset scoliosis.
- Conditions
- Early Onset Scoliosis, Congenital Spinal Deformities, Infantile Idiopathic Scoliosis, Neuromuscular Spinal Deformity
- Trial name
- GSSG (NCT02299362)
- Where
- 27 sites in United States, Canada and 5 more
- Volunteers
- 2,602 people
- Sponsor
- Growing Spine Study Group
Scoliosis; Idiopathic, Infantile, Scoliosis; Juvenile
Physical Activity, Motor Competence, Pulmonary Function, and Quality of Life in Children With Severe Spinal Disease
Observation study about physical activity, motor competence, pulmonary function, and health related quality of life in children, surgically treated for early onset scoliosis
- Conditions
- Scoliosis; Idiopathic, Infantile, Scoliosis; Juvenile, Scoliosis Neuromuscular, Scoliosis in Neurofibromatosis
- Trial name
- NCT03494829
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Scoliosis
Pulmonary Compliance Changes During Manipulation of Early Onset Scoliosis and Cast Application
No interventions outside the normal course of patient care. The investigators will be collecting data at specified points throughout the casting process.
- Trial name
- NCT02558985
- Testing
- Casting
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Indiana University
Early-Onset Scoliosis Deformity of Spine
Long-Term Follow-Up Of Surgical Management Of Early Onset Scoliosis Using Growing Rods
The aim of this work is to evaluate the long-term outcome of the graduates (those who completed the gradual lengthening procedures), to better understand the full scope and natural course of Growing Rods treatment for EOS and to…
- Trial name
- NCT04945343
- Testing
- Growing Rods
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Scoliosis
Study of the Surgical Treatment of Early Onset Scoliosis Using a Non-invasive Growing Rod
It is current practice for children who have surgery for early onset scoliosis (EOS) to be treated with insertion of extendable implants known as growth rod systems.
- Trial name
- NCT01362881
- Where
- 2 sites in United Kingdom
- Volunteers
- 14 people
- Sponsor
- Ellipse Technologies, Inc.
Early-Onset Scoliosis Deformity of Spine
Serum and Urine Titanium Levels in Children With Early Onset Scoliosis Treated With Growth-Sparing Instrumentation
The investigators are conducting research to compare serum and urine titanium levels in children with early onset scoliosis who are being treated with certain types of metal spinal rods.
- Trial name
- NCT04069637
- Testing
- Growth-sparing instrumentation and titanium levels
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Early-Onset Scoliosis Deformity of Spine
Hospital-Based Cluster Trial: Magnetically Controlled Growing Rods Using Distraction Intervals
A hospital-based cluster stratified randomization control study will be conducted to investigate spinal growth in Early Onset Scoliosis patients between 5 and 9 years of age.
- Trial name
- MCGR (NCT04058561)
- Testing
- MAGEC® Spinal Bracing And Distraction System
- Where
- 20 sites in United States, Canada and 2 more
- Volunteers
- 210 people
- Sponsor
- Pediatric Spine Foundation
Early-Onset Scoliosis Deformity of Spine (Disorder), Idiopathic Scoliosis
Limited-efficacy Testing of Spring Distraction System (SDS) and Unilateral One-way Rod (MID-C) for Early Onset Scoliosis
The primary aim of this study is to investigate the limited efficacy of these innovative surgical solutions in treatment of Early Onset Scoliosis (EOS) in terms of maintaining reduction while maintaining spinal growth.
- Trial name
- UniPOWR (NCT04003233)
- Testing
- SDS, MID-C
- Where
- 2 sites in Netherlands
- Sponsor
- UMC Utrecht
Cases of Early Onset Scoliosis
Management of Early Onset Scoliosis by Active Apex Correction Technique
Early onset scoliosis is challenging cases in management .different techniques used to correct the deformity ranging between fusionlees and fusion surgery.
- Trial name
- NCT07727408
- Testing
- Active Apex correction of scoliotic deformity
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Scoliosis Idiopathic, Early-Onset Scoliosis Deformity of Spine
Casting vs Bracing for Idiopathic Early-Onset Scoliosis
Comparison of casting and bracing for the treatment of idiopathic early onset scoliosis
- Trial name
- CVBT (NCT04500041)
- Testing
- Casting, Bracing
- Where
- 26 sites in United States, Italy and 1 more
- Volunteers
- 71 people
- Sponsor
- University of Iowa
Congenital Progressive Scoliosis, Infantile
VEPTR Implantation to Treat Children With Early Onset Scoliosis Without Rib Abnormalities
Primary Objective: To evaluate the use of unilateral or bilateral VEPTR devices, with or without expansion thoracoplasty, for preventing further progression of the Cobb angle, allowing for spinal growth and improving pulmonary…
- Trial name
- NCT00689533
- Where
- 3 sites in United States
- Volunteers
- 250 people
- Sponsor
- Shriners Hospitals for Children
Adolescent Idiopathic Scoliosis (AIS), Ealy Onset Scoliosis
Development of a Conservative Care and Bracing Registry (CCBR)
Idiopathic scoliosis (IS) is a common problem affecting approximately 3% of the population; its progression can lead to significant health problems.
- Conditions
- Adolescent Idiopathic Scoliosis (AIS), Ealy Onset Scoliosis, Juvenile Idiopathic Scoliosis, Infantile Idiopathic Scoliosis
- Trial name
- CCBR (NCT07527611)
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- National Scoliosis Center
Scoliosis
Curve Correction of Early Onset Scoliosis by Mehta Serial Casts
Assessment of the role of Mehta Serial Casts in Curve Correction of Early Onset Scoliosis
- Trial name
- NCT06277089
- Testing
- Casts
- Volunteers
- 5 people
- Sponsor
- Assiut University
Early Onset Scoliosis (EOS)
Safety and Efficacy Evaluation of Insight GS Growing System
Premarket, interventional, single-arm clinical study, to evaluate the safety and efficacy of Insight GS Growing System in the surgical treatment of Early Onset Scoliosis (EOS).
- Trial name
- NCT06301984
- Testing
- Insight GS
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- EVEREST PESQUISA E DESENVOLVIMENTO LTDA
Scoliosis, Scoliosis Idiopathic
Minimal Invasive Deformity Correction (MID-C) System for Early Onset Scoliosis
Early Onset Scoliosis (EOS) is defined as scoliosis with onset under the age of ten years, regardless of etiology. It is a complex three-dimensional deformity of the spine which can cause significant physical and psychological…
- Conditions
- Scoliosis, Scoliosis Idiopathic, Scoliosis;Congenital
- Trial name
- NCT03519321
- Testing
- MID-C
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Apifix
Early Onset Scoliosis (EOS)
Active Apex Correction (APC) for Early Onset Scoliosis. Early Results of a Pilot Study.
The primary objective of this study is to evaluate the early results of Active Apex Correction (APC) technique for managing early onset scoliosis.
- Trial name
- APC-EOS (NCT07429656)
- Testing
- Active Apex Correction (APC)
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Assiut University
Neuromuscular Scoliosis, Distraction System
Limited-efficacy Testing of SDS and NEMOST for Early Onset Neuromuscular Scoliosis
The primary aim of this study is to investigate and describe the limited efficacy of the Spring Distraction System (SDS) and Bilateral One Way Rod (NEMOST) in maintaining curve reduction without repeat lengthening procedures and…
- Conditions
- Neuromuscular Scoliosis, Distraction System, Growth Friendly System
- Trial name
- BiPOWR (NCT04021784)
- Testing
- SDS, NEMOST
- Where
- 3 sites in Netherlands
- Volunteers
- 28 people
- Sponsor
- UMC Utrecht
Juvenile Idiopathic Arthritis (JIA), Fibromyalgia
Biopsychosocial Risk Influences on the Development and Generation of Early-Onset Chronic Pain
The purpose of the study is to discover the underlying subtypes of chronic musculoskeletal pain (muscle and joint pain) in youth.
- Conditions
- Juvenile Idiopathic Arthritis (JIA), Fibromyalgia, Lupus, Scoliosis
- Trial name
- BRIDGE Pain (NCT07602595)
- Testing
- Not applicable- observational study
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Early Onset Scoliosis
Evaluation of a Modern System to Allow for Growth in Children With Scoliosis Versus a Conventional Treatment
The foremost challenge when managing early onset scoliosis (curve deformity before the age of 10) is to prevent curve progression while maintaining growth of the spine.
- Trial name
- NCT01672749
- Testing
- Growth guiding construct using TROLLEY system, Spine based dual growing rod or rib based VEPTR
- Where
- 3 sites in Switzerland, United Kingdom
- Volunteers
- 18 people
- Sponsor
- AO Innovation Translation Center