Clinical trials: Eating Disorder
Anorexia Nervosa, Anorexia Nervosa Restricting Type
Novel Targetable BIOmarkers in ANorexia NervosA
The overall aim of this present study is to evaluate Growth Differentiation Factor-15 (GDF-15) and inflammatory cytokines as a possible novel and readily treatable target for the successful therapy of Anorexia Nervosa (AN).
- Trial name
- BIOANNA (NCT05885724)
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Obesity, Obesity & Overweight
Interaction of Sleep, Diurnal Eating Pattern, Gut Microbiota, and Obesity
The goals of the proposed study are 1) to provide scientific basis for the relationship between subjective sleep quality, diurnal eating pattern, gut microbiome, and obesity, 2) to develop and test a pragmatic, cost-effective new…
- Trial name
- ObeApp (NCT04850391)
- Testing
- Mobile app
- Where
- Finland
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Sedentary Behavior, Adipose Tissue
Participatory Intervention to Improve Nutrition and Physical Activity in Schoolchildren From Acatlán de Juárez, Jalisco
This is a community project carried out jointly by the Technological Institute of Higher Studies of the West (ITESO), the University Center of Tonalá of the University of Guadalajara (CUTonalá) and the University Center of Health…
- Conditions
- Sedentary Behavior, Adipose Tissue, Child Obesity
- Trial name
- Acatlan (NCT04679246)
- Testing
- Participatory intervention
- Where
- Mexico
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Iberoamerican Institute of Sports Science and Human Movement
Anorexia Nervosa, Cardiac Anomaly
Evaluation of CARdiac Abnormalities by Echocardiography and MRI in Malnourished Patients Suffering From Anorexia Nervosa
Anorexia nervosa is an eating disorder occurring in adolescent females, characterized by voluntary dietary restriction, intense fear of gaining weight, and disturbed body image perception.
- Trial name
- CARERA (NCT03600610)
- Testing
- gadolinium-enhanced cardiac MRI
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Healthy Subjects, Obesity
Glucagon Modulation of Ghrelin Secretion
As a counterregulatory hormone for insulin, glucagon plays a critical role in maintaining glucose homeostasis in vivo. It is well known that intramuscular glucagon administration stimulates growth hormone (GH)…
- Conditions
- Healthy Subjects, Obesity, Diabetes Mellitus, Type 1
- Trial name
- NCT00929812
- Testing
- Glucagon hydrochloride (GlucaGen®), NaCl 0.9%
- Where
- Germany
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Resilience, Practice Readiness
Evaluation of an Interactive Mental Wellness (I-AM-WELL) Program on Final Year Nursing Students
This study aims to address the following research questions: Evaluate the effectiveness of an Interactive Mental Wellness (I-AM-WELL) program on final year nursing students' anxiety, depression, stress, resilience, practice…
- Conditions
- Resilience, Practice Readiness, Depression, Anxiety
- Trial name
- I-AM-WELL (NCT06169293)
- Testing
- I-AM-WELL
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Weight Loss, Obesity
The Effects of Exenatide (Byetta ) on Energy Expenditure and Weight Loss in Nondiabetic Obese Subjects
Exenatide is an incretin-like drug that has been approved for treatment of type 2 diabetes; it improves glycemia by increasing insulin and decreasing glucagon secretion by pancreatic islet cells and delaying gastric emptying.
- Trial name
- NCT00856609
- Testing
- Byetta (exenatide), Weight loss, Metabolic Chamber
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pediatric Obesity, Pediatric Nutrition
Storybook-Based Nutrition Education for Preschoolers
This project aims to design a nutrition-based educational storybook for preschool children and to evaluate its effect on improving general nutrition behaviors and reducing possible picky eating habits.
- Conditions
- Pediatric Obesity, Pediatric Nutrition, Nutrition Education, Nutrition Education Program
- Trial name
- NCT07540234
- Testing
- Behavioral Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Feeding and Eating Disorders of Childhood
Technology-supported Behavioral Feeding Intervention
This investigation proposes to examine the effectiveness of a technology supported treatment manual for pediatric feeding disorders.
- Trial name
- NCT02119910
- Testing
- Technology Supported Manual
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Emory University
Schizophrenia, Bipolar Disorder
Resting State Electroencephalogram for Psychotic Disorders
Electroencephalography (EEG) has been proposed as a neurophysiological biomarker to delineate psychotic disorders. Meanwhile, the increased appetite, which might related to self-control process, has been an increasing concern for…
- Conditions
- Schizophrenia, Bipolar Disorder, Depression
- Trial name
- NCT05065489
- Testing
- No intervention
- Where
- China
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Central South University
Anorexia Nervosa, Bulimia Nervosa
Eating Disorders Genetics Initiative 2
The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes.
- Conditions
- Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder, Avoidant Restrictive Food Intake Disorder
- Trial name
- EDGI2 (NCT06594913)
- Testing
- Eating disorder diagnosis group
- Where
- 5 sites in United States, Australia and 3 more
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity
Healthy Kids & Families: Overcoming Social, Environmental and Family Barriers to Childhood Obesity Prevention
The study will test the impact of a community health worker (CHW)-delivered intervention aimed at helping families overcome barriers to childhood obesity prevention. Barriers include social, environmental, and family issues.
- Trial name
- NCT03028233
- Testing
- Healthy Lifestyle, Positive Parenting
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Major Depressive Disorder (MDD), Rumination
Neurobiological Mechanisms of Pathological Rumination and Effects of Aripiprazole
This randomized, single-blind (assessor-blind) controlled trial aims to investigate the efficacy of aripiprazole as an augmentation strategy for treating pathological rumination in patients with major depressive disorder (MDD).
- Trial name
- NCT06937476
- Testing
- Escitalopram, Aripiprazole 5mg
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Central South University
Obesity
The Impact of Morning or Evening Exercise on Food Intake
The beneficial effects of regular exercise on both physical and mental health are widely known; it is a pivotal component in the treatment and prevention of many metabolic disorders, including obesity.
- Trial name
- TIME-Ex-Ulster (NCT04720950)
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Obesity
High-intensity Intermittent Training for Obese Individuals
The most appropriate and effective exercise interventions for weight loss remain a matter of continued discussion and there is a need to identify sustainable exercise programs which successfully promote weight loss and benefit…
- Trial name
- NCT01143376
- Testing
- High intensity training, short springs, Moderate intensity exercise
- Where
- Norway
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Childhood Obesity, Overweight and Obesity
Childhood Obesity - Prevention of Diabetes Through Changed Eating Patterns
The main purpose of the present study is to perform a 10 weeks dietary intervention study with a follow-up for 52 weeks in children from 7-14 years of age with overweight or obesity.
- Conditions
- Childhood Obesity, Overweight and Obesity, Adolescent Obesity, Adolescent Overweight
- Trial name
- COPE (NCT04522921)
- Testing
- Diet with a higher amount of protein (25E% per day), Increased follow-up contact after the 10-week intervention, Diet with a lower amount of protein (15E% per day)
- Where
- 2 sites in Denmark
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Obesity
Effect of Hydroxychloroquine Sulphate in Healthy Lean Females
The effect of an acute administration of hydroxychloroquine sulphate will be investigated on hedonic food intake, appetite related sensations and gastrointestinal hormone release in healthy female subjects.
- Trial name
- PLAQHV (NCT04005768)
- Testing
- Hydroxychloroquine Sulphate
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pediatric Obesity, Executive Function
Acceptance-based Care for Child Eating and Physical Activity Treatment
The purpose of this study is to develop and pilot test a new type of patient-centered, family-based treatment for children aged 8-12 with obesity and their caregivers.
- Conditions
- Pediatric Obesity, Executive Function, Self-Regulation
- Trial name
- ACCEPT (NCT03368716)
- Testing
- Acceptance-based Behavioral Treatment (ABBT)
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity
Safety and Pharmacokinetic Study of Y242 in Adult Subjects
Obesity causes 600 premature deaths per week in the UK and existing treatments are not effective. When humans eat, the bowels naturally secrete chemicals into the bloodstream which make people feel full and which stop eating.
- Trial name
- Y242-01 (NCT01515319)
- Testing
- Y242, 0.9% saline
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity
The Effect of Fatty Acid Composition on Energy Intake and Satiety
The objective of the study is to investigate the effect of fatty acid composition of a fat supplement: 1. acutely (after single intake) on subjective and objective measurements of hunger, satiety and wellness, on energy intake…
- Trial name
- NCT00242021
- Testing
- Fatty acid composition of a margarine (spread)
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- TNO
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