Clinical trials: Eating Disorder
Anorexia Nervosa, Microbiome Dysbiosis
Feasibility Study of Using Fecal Microbiota Transplants in Anorexia Nervosa
The investigators hypothesize that prolonged undernutrition in anorexia nervosa alters the microbiome to a different steady-state (dysbiotic) composition that sustains the disease, even after returning to normal diet.
- Trial name
- ReBoot (NCT05834010)
- Testing
- Fecal Microbiome Transplant
- Where
- 3 sites in Denmark
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Feasibility Studies, Acceptability
Feasibility and Acceptability of a Single Session of Imagery Rescripting in a Community Sample of Adults
Negative experiences related to eating and appearance (NEREAs), such as critical commentary from parents about food, are common. They are also associated with depression and disordered eating, predictors of early mortality.
- Conditions
- Feasibility Studies, Acceptability, Depressive Symptoms, Disordered Eating Behaviors
- Trial name
- NCT06610318
- Testing
- imagery rescripting, nutrition education
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Healthy Diet, Stress
Happy Family, Healthy Kids Program
Happy Family, Healthy Kids program, funded by the Michigan Health Endowment Fund, is a 14-week healthy eating program aimed to foster "Happy Family \& Healthy Kids." The program will target parental emotional eating through a…
- Conditions
- Healthy Diet, Stress, Pediatric Obesity, Intergenerational Relations
- Trial name
- NCT04183179
- Testing
- Happy Family, Healthy Kids Program
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Obesity, Meal Frequency
Time Restricted Eating and Meal Frequency for Appetite Control
Obesity is one of the largest worldwide health problems. There are increasing rates of overweight and obesity, and in recent years, worldwide the percentage of overweight and obesity among adults now exceeds 1.9 billion and 650…
- Conditions
- Obesity, Meal Frequency, Appetite, Body Composition
- Trial name
- TRE (NCT07805291)
- Testing
- MT1, MT2
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Eating Disorder, Body Image
The Pride Body Project
The purpose of this study is to better investigate the efficacy of the PRIDE Body Project in respect to preventing eating disorders in sexual minority men.
- Trial name
- PBP (NCT03451513)
- Testing
- Pride Body Project, Media Advocacy
- Where
- United States
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Anorexia Nervosa
Metabolic Phenotyping in Anorexia Nervosa
After discharge from inpatient treatment, 30-50% of patients with Anorexia Nervosa require re-hospitalization within 4-12 months.
- Trial name
- NCT02087280
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Vascular Stiffness, Hypertension (HTN)
Low Energy Availability and Hypertension in Division I HBCU Athletes
Low energy availability (LEA) occurs when the body does not get enough calories to support both daily life and exercise. This can happen when athletes train hard but do not eat enough to match their energy needs.
- Conditions
- Vascular Stiffness, Hypertension (HTN), Nutritional Deficiency Related Cardiovascular Risk in Athletes
- Trial name
- CORE-DI (NCT07583940)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- North Carolina Agriculture & Technical State University
Anorexia Nervosa
Estradiol and Fear Extinction in Anorexia Nervosa (AN)
The purpose of this study is to determine whether estrogen may help reduce fear of high calorie-density foods in weight-restored women with Anorexia Nervosa (AN).
- Trial name
- NCT02792153
- Testing
- Estradiol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Anorexia Nervosa
Metabolic Diet for Relapse Prevention in Anorexia Nervosa
This is an interventional study that will test the safety, tolerability, and efficacy of the Metabolic Diet, which was designed as a treatment for women with anorexia nervosa to remain weight-stable after they have been restored…
- Trial name
- NCT05197309
- Testing
- Metabolic Diet
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obesity, Child Obesity
Family COMIDA (Consumo de Opciones Más Ideales De Alimentos) (Eating More Ideal Food Options)
The purpose of this study is to determine the most effective family-centered intervention (FCI) for weight loss and obesity prevention in Hispanic families.
- Conditions
- Obesity, Child Obesity, Weight Loss
- Trial name
- NCT07144800
- Testing
- Parent Weekly Individual Telephone Support, Child Education, Parent Initial Counseling
- Where
- United States
- Volunteers
- 1,319 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Obesity
LEAP2 on Postprandial Glucose Metabolism and Food Intake n Obese Males
The study aims to delineate the effects of the naturally occurring peptide liver-enriched antimicrobial peptide 2 (LEAP-2) on postprandial glucose metabolism and food intake in obese volunteers.
- Trial name
- LEAP2-OBCT (NCT05603598)
- Testing
- LEAP-2 Protein, Human
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Cardiovascular Disease Risk Factors, Overweight and Obesity
Nutritious Eating With Soul (The NEW Soul Study)
This study addresses two challenges seen among African American (AA) participants during previous weight loss and dietary interventions aimed at reducing cardiovascular disease (CVD) risk: poor weight loss results and high…
- Trial name
- NCT03354377
- Testing
- Dietary Intervention Meetings, Physical Activity, Podcasts/Mailings
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Eating Disorder Prevention, Eating Disorders
Early Detection of Patients with Eating Disorders in General Practice
The goal of this observational study is to assess the efficacy of the Eating Disorder Proxy Screening Tool for General Practitioner (ED-PSTGP) as a tool for the early detection of eating disorders (EDs) in General Practice (GP).
- Trial name
- NCT06595381
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Donini Lorenzo M
Anorexia Nervosa, Major Depressive Disorder
Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa
This study aims to identify the brain regions responsible for encoding cardiorespiratory 'interoceptive' sensations and determine whether they are dysfunctional in individuals affected by eating disorders, anxiety, depression, or…
- Conditions
- Anorexia Nervosa, Major Depressive Disorder, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- NCT02615119
- Testing
- Isoproterenol, Normal saline
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Shift Work Type Circadian Rhythm Sleep Disorder, Eating Behavior
Eating Behaviors in Shift Workers
This study will compare eating behaviors and measures of hunger and fullness between day and night workers in order to better understand why night workers are at increased risk for obesity and related diseases.
- Trial name
- NCT04468672
- Testing
- Portion size
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University
Microbial Colonization
Gut Health Enhancement by Eating Favourable Food
Within the GEEF om je buik study the effects of an 8-week intervention with either a diet rich in fiber or fermented food on the gut microbiota will be investigated.
- Trial name
- GEEFomjebuik (NCT05900609)
- Testing
- WholeFiber, Kombucha, Maltodextrin DE19/21
- Where
- Netherlands
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Obesity
Craving and Lifestyle Management Through Mindfulness Study
The purpose of this study is to determine whether a mindfulness-based stress reduction and mindful eating program will lead to reductions in abdominal fat and total weight and improve cell aging in overweight and obese women…
- Trial name
- CALMM (NCT01250509)
- Testing
- Craving and Lifestyle Management through Mindfulness
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anorexia Nervosa, Hypothalamic Amenorrhea
Hormone Dynamics and Bone Mineral Density in Anorexia Nervosa v. Hypothalamic Amenorrhea
The purpose of this study is to determine whether the hormone dynamics in women with anorexia nervosa and hypothalamic amenorrhea is related to bone loss in those populations.
- Conditions
- Anorexia Nervosa, Hypothalamic Amenorrhea, Obesity
- Trial name
- NCT00556036
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pediatric Obesity, Binge-Eating Disorder
Project THINK: Trajectories of Health, Ingestive Behaviors, and Neurocognition in Kids
Overweight/obesity and loss of control eating (characterized by the sense that one cannot control what or how much one is eating) are prevalent among children and adolescents, and both are associated with serious medical and…
- Trial name
- NCT04701671
- Testing
- Observational (not including MRI scanning), Observational (including MRI scanning)
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Hypertension, Obesity
Radio Stories About Children's Healthy Eating and Exercise
The purpose of this study is to use a community based participatory action research (CBPAR) approach to 1) create "radio stories" about Somali, Latino and Hmong families' real success stories with hypertension and obesity in…
- Trial name
- NCT02139787
- Testing
- Radio Story, Control -listened to a brochure
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
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