Clinical trials: Eclampsia
Pre-Eclampsia
Prenatal Yoga as Complementary Therapy of Preeclampsia
Preeclampsia is a specific pregnancy disorder that complicates approximately 3-5% of all pregnancies. The effects on pregnant women vary from mild hypertension, severe hypertension / hypertensive crisis, eclampsia to hemolysis…
- Trial name
- NCT04795154
- Testing
- Yoga excercise
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Preeclampsia, Preeclampsia Postpartum
MR and Inflammation After Preeclampsia
The purpose of this investigation is to examine the role of inappropriate mineralocorticoid receptor activation in endothelial dysfunction and vascular inflammation in otherwise healthy women with a history of preeclampsia.
- Trial name
- NCT07345845
- Testing
- Eplerenone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Pre-Eclampsia
L-Arginine in Pre-Eclampsia
Pre-eclampsia is a disorder unique to pregnancy affecting both the mother and the fetus. Hypertension, proteinuria and edema are the most common and well-known maternal clinical symptoms. The incidence is approximately 6-8%.
- Trial name
- NCT00157521
- Testing
- L-arginine
- Where
- 2 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Pre-Eclampsia
Midkine Role With Deregulated Oxidative and Immune Milieu in Induction of Preeclampsia
Preeclampsia (PE) is a hypertensive pregnancy-related disorder that endangers maternal and fetal outcomes and accounts for 9-10% of maternal mortalities with its early-onset phenotype is the most dangerous, but its etiology is…
- Trial name
- NCT06329284
- Testing
- ELISA
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Benha University
Preeclampsia, Pregnancy Induced Hypertension
Preeclampsia: A Marker for Future Cardiovascular Risk in Women
This study will compare blood vessel and hormone differences between women who have a history of a pregnancy complicated by preeclampsia or high blood pressure, and women who have a history of uncomplicated pregnancy in the last…
- Trial name
- NCT01519297
- Testing
- Irbesartan
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pre-Eclampsia, Pregnancy
Women Specific Cardiac Recovery After Preeclampsia
Pregnancy is considered a cardiovascular (CV) stress test, and complicated pregnancies are associated with an increased risk for cardiovascular disease (CVD) later in life.
- Conditions
- Pre-Eclampsia, Pregnancy, HELLP Syndrome, Intrauterine Growth Restriction
- Trial name
- WeCare (NCT02807324)
- Testing
- Venapunction
- Where
- Netherlands
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Preeclampsia
Family Study on Preeclampsia
This study will examine a possible genetic basis for preeclampsia, a disorder of high blood pressure and protein in the urine during pregnancy. Preeclampsia is a major pregnancy complication affecting both mother and baby.
- Trial name
- NCT00344162
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pre-Eclampsia, HELLP Syndrome
PlacEntal Acute Atherosis RefLecting Subclinical Atherosclerosis
Pregnancy is considered a cardiovascular (CV) stress test, and complicated pregnancies are associated with an increased risk for cardiovascular disease (CVD) later in life.
- Conditions
- Pre-Eclampsia, HELLP Syndrome, Intrauterine Growth Restriction, Pregnancy
- Trial name
- PEARLS (NCT05500989)
- Where
- Netherlands
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Preeclampsia
ToRsemide for pOstpartum HYpertension
Currently there is no intervention to prevent persistent postpartum hypertension in preeclamptic women. Physiologically, the use of a pharmacokinetically predictable loop-diuretic is a reasonable intervention to increase…
- Trial name
- TROPHY (NCT02813551)
- Testing
- Torsemide
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Hypertension With Pregnancy
Evaluation of Psychological Status in Pregnant Women Complaining of Hypertension With Pregnancy
This study is a case controlled study comparing mental health status and some psychological impacts between two groups of patients first group is pregnant women without any other medical disorder during pregnancy,the second group…
- Trial name
- NCT03503383
- Testing
- Patient Health Questionnaire-9, Generalized Anxiety Disorder Scale (GAD-7)
- Where
- 2 sites in Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Preeclampsia
Cornell University-Micronutrient Initiative Calcium Supplementation Study
The World Health Organization (WHO) now recommends prenatal calcium supplementation for prevention of preeclampsia in populations with inadequate dietary intake.
- Trial name
- MICA (NCT02238704)
- Testing
- Regimen A calcium and iron/folic acid, Regimen B calcium and iron/folic acid
- Where
- 16 sites in Kenya
- Volunteers
- 1,032 people, healthy volunteers welcome
- Sponsor
- Cornell University
Pregnancy Complications
Measuring sVAP-1 as a Predictor of Pregnancy Problems
Pre-eclampsia is a common pregnancy disorder defined as high blood pressure and protein in the urine after 20 weeks of pregnancy.
- Trial name
- NCT04891315
- Testing
- Blood test for soluble VAP-1 (sVAP-1).
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Hypertension, Premature Birth
Trial of Exercise to Prevent HypeRtension in Young Adults
TEPHRA investigates the effect of exercise on blood pressure and other cardiovascular factors in young adults with different birth histories.
- Trial name
- TEPHRA (NCT02723552)
- Testing
- Aerobic Exercise
- Where
- United Kingdom
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Pre-Eclampsia
Study for Improving Maternal, Pregnancy and Child Outcomes
The overall aims of this proposal are to improve, facilitate, optimize and equalize the existing screening system for adverse pregnancy outcomes in early pregnancy in order to limit adverse consequences for both the mother and…
- Trial name
- IMPACT (NCT03831490)
- Testing
- history
- Where
- 9 sites in Sweden
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Pre-Eclampsia
CA-125 and Severity of Pre-Eclampsia
The Aim of this study is to determine the relationship between serum concentrations of cancer antigen-125 (CA-125) and pre-eclampsia severity.
- Trial name
- NCT02704676
- Testing
- marker(CA-125)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Hypertension
Nonsteroidal Antiinflammatory Drugs in Women With Postpartum Pre-eclampsia
Hypertensive disorders of pregnancy are a major cause of maternal mortality and morbidity, especially in developing countries. Postpartum hypertension can be related to persistence of gestational hypertension, preeclampsia, or…
- Trial name
- NCT01988298
- Testing
- Ibuprofen, Acetaminophen
- Where
- Panama
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Complejo Hospitalario Dr. Arnulfo Arias Madrid
Preeclampsia
Exercise Induced Improvement of the Venous Reserve Capacity in Formerly Pre-eclamptic Women
Primary objective: To investigate whether physical exercise prior to pregnancy in formerly preeclamptic women results in a comparable improvement of vascular and endothelial functioning as in women who had an uneventful…
- Trial name
- NCT00900458
- Testing
- Aerobic Exercise training
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Gestational Complications, Body Mass Index
Antenatal Body Shape Index and Pregnancy Complications
Background/aim: Gestational diabetes (GDM), gestational hypertension (GHT) and preeclampsia are common complications of pregnancy.
- Conditions
- Gestational Complications, Body Mass Index, Waist Circumference, Gestational Hypertension
- Trial name
- NCT07022158
- Testing
- The patients participating in the study were between 6 and 16 weeks of pregnancy. Height, body weight, and waist circumference were measured at the first antenatal visit at 2 weeks.
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Pregnancy Related, Remote Monitoring
Feasibility of Remote eCTG Monitoring Home@Hospital in Complicated Pregnancies
The objective of this single center, interventional cohort study is to evaluate the feasibility of remote electrophysiological cardiotocography (eCTG) monitoring in complicated pregnancies in a home@hospital setting.
- Conditions
- Pregnancy Related, Remote Monitoring, Feasibility
- Trial name
- HASTA (NCT06859177)
- Testing
- Remote eCTG
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Preeclampsia Postpartum, Adverse Pregnancy Outcomes
A Community Health Worker Intervention to Address Adverse Pregnancy Outcomes
United States maternal mortality and preterm birth rates are among the highest among high-income countries due in part to a combination of racial, regional and socioeconomic disparities in access to care and overall health.
- Trial name
- AW2H (NCT06353256)
- Testing
- usual postpartum care, usual postpartum care + community health worker intervention
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham