Clinical trials: Edentulism, open to volunteers
Atrophic Maxilla, Partial Edentulism
Prospective Study of Bone Augmentation With Lateral Sinus Lift and Osseointegration of Dental Implants
By using a split-mouth model in the maxilla, lateral sinus lift procedures will be performed using xenograft on one side vs autologous bone augmentation and PRF membranes on the other side.
- Trial name
- NCT07014085
- Testing
- "Histomorphometric Evaluation of Bone Augmentation Using Xenografts Versus Autologous Bone Grafts in Dental Implant Patients: A Comparative Clinical Study
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maria H. Pham
Edentulism in Lower Jaw, Edentulism
Evaluation of Different Attachments on Implant-Retained Mandibular Overdenture.
Patients will be selected from the outpatient clinic of Removable Prosthodontic Department. Faculty of Dental Medicine for Girls, Al-Azhar University..
- Trial name
- Overdenture (NCT06721377)
- Testing
- Novaloc attachment, Equator attachment
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Failure, Prosthesis, Dental Prosthesis, Implant-Supported
Clinical Performance of All-on-4 PEEK and Conventional Prostheses
The all-on-4 treatment approach for completely edentulous mandible is a proven concept. However, there are still issues regarding the use of metal substructure to support the prostheses such as allergy, metallic taste, and…
- Conditions
- Failure, Prosthesis, Dental Prosthesis, Implant-Supported, Survival, Prosthesis, Complete Edentulism
- Trial name
- NCT06388395
- Testing
- Accuracy of full-arch surgical guides, Survival and complications of the prostheses, Survival and complications of the implants
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Dental Implants, TNF-alpha Inhibitors
Dental Implant Healing With TNF-Alpha Inhibitors
The goal of this pilot study is to learn about healing after dental implant placement in patients taking a class of biologic drug called Tumor Necrosis Factor or TNF-alpha antagonist or inhibitor.
- Conditions
- Dental Implants, TNF-alpha Inhibitors, Edentulism
- Trial name
- NCT06538870
- Testing
- Placement of dental implants
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Frailty, Malnutrition
Impact of Auditory Stimulation in Eating Pleasure (EDERE 2021)
Background. Decreased taste and smell contribute to loss of appetite (anorexia), and the resulting protein-energy malnutrition increases the frailty of the elderly.
- Conditions
- Frailty, Malnutrition, Anorexia, Presbycusis
- Trial name
- EDERE 2021 (NCT04923087)
- Testing
- Compare the noise and pleasure of crunching between two hyperprotein nutritional supplements
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Edentulism
A Clinical Trial of Dental Device Cemented with Polymethyl Methacrylate (PMMA) Bone Cement
Conventional bridge and dental implants have been playing a significant role in replacing missing tooth/teeth. But they come with shortcomings.
- Trial name
- NCT06018701
- Testing
- A dental device made of zirconia. This is a new invention and does not exist generically. The given generic name of the invention (dental device) is "Dantya Nikhan".
- Where
- Nepal
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bluebird International Clinic
Complete Edentulism, Maxillary Complete Denture Rehabilitation
3D Printing Orientation and Film Thickness for Maxillary Complete Dentures
This randomized crossover clinical trial aims to evaluate the effect of different three-dimensional (3D) printing orientations and layer thicknesses on the trueness, dimensional accuracy, and patient satisfaction of maxillary…
- Conditions
- Complete Edentulism, Maxillary Complete Denture Rehabilitation, Prosthodontics, 3d Printing
- Trial name
- NCT07740278
- Testing
- 0° 3D-Printed Maxillary Complete Denture, 45° 3D-Printed Maxillary Complete Denture, 90° 3D-Printed Maxillary Complete Denture
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tanta University
Subtotal Edentulism
Polyoxymethylene (POM) in the Production of Telescopic Denture in Older Adults With Subtotal Edentulism
The mail goal of this study is to evaluate the success of the prosthetic treatment with telescopic removable partial denture with framework made of polyoxymethylene (POM).
- Trial name
- NCT06593925
- Testing
- Production of polyoxymethylene telescopic denture, Production of conventional complex partial denture with clasps
- Where
- Serbia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Edentulous Alveolar Ridge In Mandible, Complete Edentulism
Evaluation of Bone Changes Around Implants in Patients Treated With All on Four
The Goal of the clinical trail is to evaluate the Bone height changes around two axially placed anterior implants and two distally inclined 30-degree angle posterior implants in comparison to two axially placed anterior implants…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Complete Edentulism, All on Four Technique, Dental Implant
- Trial name
- NCT06723678
- Testing
- Two distally inclined 45-degree angle posterior implants, Two distally inclined 30-degree angle posterior implants
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Edentulism in Lower Jaw
Accuracy of Immediate Implant Placement
This randomized clinical study will compare the accuracy of immediate implant placement performed using three different surgical approaches: freehand surgery, conventional tooth-supported static computer-guided surgery, and a…
- Trial name
- NCT07863700
- Testing
- Freehand Immediate Implant Placement, Tooth-Supported Static Computer-Guided Implant Placement, Tooth- and Socket-Supported Static Guided Implant Placement
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Partial Edentulism, Tooth Loss / Rehabilitation
In Vivo Evaluation of the Accuracy of Immediate Screw-Retained Provisional Crowns Fabricated Using Digital Planning and Guided Surgery
This clinical trial aims to evaluate the in vivo accuracy of a fully digital workflow for the immediate placement of a previously fabricated screw-retained provisional crown using digital planning and guided implant surgery.
- Trial name
- NCT07315607
- Testing
- Fully Guided Implant Placement and Immediate Provisionalization
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Complete Edentulism
Implementation of Digital Workflow for Complete Dentures - A Crossover Study
With a demographically ageing population and increasing patients with missing teeth, the demands on the healthcare system are set to further increase.
- Trial name
- NCT06457321
- Testing
- Sequence in receiving the fabricated dentures made using the conventional and partial digital method
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Dental Centre, Singapore
Edentulism, Malocclusion; Displaced Teeth
Augmented Reality Dentistry
This study aims to evaluate the accuracy of augmented reality (AR)-assisted dental procedures. Patient-specific anatomical data will be acquired using cone-beam computed tomography (CBCT) and intraoral scanning and integrated to…
- Conditions
- Edentulism, Malocclusion; Displaced Teeth, TEETH EXTRACTION
- Trial name
- AugRealDent (NCT07814794)
- Testing
- Surgery, Patients requiring orthodontic treatment.
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Edentulism Complete
3D Metrology-Based Comparison of Functional Casts Made With Conventional and 3D-Printed Custom Trays
This study will compare the dimensional discrepancies of functional casts obtained using conventional custom trays and 3D-printed custom trays made from PET-G (Polyethylene Terephthalate Glycol) filament.
- Trial name
- NCT07787715
- Testing
- Conventional PMMA Custom Tray, 3D-Printed Custom Tray
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Implant Healing, Partial Edentulism Class 1
Internal Irrigation Surgery
Heat generated during osteotomy and implant placement may cause thermal injury to bone and adversely affect healing and osseointegration.
- Conditions
- Dental Implant Healing, Partial Edentulism Class 1, Partial Edentulism Class II, Partial Edentulism Class 3
- Trial name
- NCT07715825
- Testing
- Irrigation-Integrated Surgical Guide, Conventional Surgical Guide
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Edentulism
3D-Printed Implant Overdentures: Comparing Impression Techniques
This randomized crossover clinical trial aims to compare three different impression techniques for the construction of 3d-printed mandibular implant overdentures in completely edentulous patients.
- Trial name
- NCT07208812
- Testing
- Conventional open -tray impression, Functionally generated reline impression, Mucostatic base with functional borders impression
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Edentulism
The Impact of Palatal Rugae Addition to Complete Dentures on Patients' Satisfaction and Oral Health Related Quality of Life
In conventional maxillary complete dentures, the palatal surface is typically smooth and polished, lacking the natural anatomy of the palatal rugae.
- Trial name
- Palatal rugae (NCT07034079)
- Testing
- complete dentures
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Edentulism, Complete Dentures
The Effect of Palatal Rugae Design in Complete Denture on Patient Satisfaction and Quality of Life
The goal of this clinical trial is to learn whether different palatal rugae designs in complete dentures can improve comfort, function, and overall oral health-related quality of life in edentulous adults aged 40 to 80 years.
- Trial name
- NCT07579377
- Testing
- Polished Palatal Surface Denture, Roughened Palatal Rugae Design, Vacuum-Formed Thermoplastic Sheet Rugae Denture
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences